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The AI-powered KisoSeek™ platform identifies functional anti-TROP2 heavy-chain antibodies with potent anti-cancer activity Cousineau, Sophie E.; Subedi, Amit; Wargachuk, Richard; The, Juliana; Wang, Xiaowei; Hou, Wenyang; Nair, Amogh; Qiu, Wansu; Zhou, Alex; Cheng, Tiffany; Babaie, Morteza; Gojogh, Benyamin; Montero, Marinieve; Zahreddine, Hiba; Undzys, Elijus; Lai, Lucy; Ngan, Gordon; Da Cruz, Luis; Young, David 分享 收藏
Pre-clinical development of a dopamine receptor 2, PD-1, and CD47 trispecific antibody for the treatment of solid tumors Yao, Shugang; Zahreddine, Hiba; Hou, Dominic; Undzys, Elijus; Gong, Liying; Wargachuk, Richard; Wang, Xiaowei; Zhou, Alex; Lai, Lucy; Da Cruz, Luis A.; Young, David 分享 收藏
Functional characterization of KJ-103, a novel therapeutic anti-TROP2 heavy chain- only antibody Yao, Shugang; Zahreddine, Hiba; Subedi, Amit; Gong, Liying; Nair, Amogh; Zhou, Alex; Cheng, Tiffany; Undzys, Elijus; Hou, Dominic; Lai, Lucy; Da Cruz, Luis A.; Young, David 分享 收藏
Programmed Cell Death-1 (PD-1) anchoring to the GPI-linked co-receptor CD48 reveals a novel mechanism to modulate PD-1-dependent inhibition of human T cells 程序性细胞死亡-1 (PD-1) 锚定到GPI连接的共受体CD48揭示了一种调节人类T细胞PD-1-dependent抑制的新机制 White, Della; Cote-Martin, Alexandra; Bleck, Marina; Garaffa, Nicole; Shaaban, Abdulsalam; Wu, Helen; Liu, Dongmei; Young, David; Scheer, Justin; Lorenz, Ivo C.; Nixon, Andrew; Fine, Jay S.; Byrne, Fergus R.; Mbow, M. Lamine; Moreno-Garcia, Miguel E. 分享 收藏
Discovery of novel functional TROP2 antibodies for treatment of epithelial cancers Matos, Israel; Zahreddine, Hiba; Ashraf, Yahya; Pandey, Aditya; Chen, Emily; Gong, Liying; Zhou, Alex; Bonfils, Claire; Moya, Aniel; Cui, Yun; Wang, Xiaowei; Undzyz, Elijus; Yao, Shugang; Toulouse, Jacynthe; Hou, Dominic; Ngan, Gordon; da Cruz, Luis; Young, David 分享 收藏
Intranasal Administration of a Monoclonal Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection Halwe, Sandro; Kupke, Alexandra; Vanshylla, Kanika; Liberta, Falk; Gruell, Henning; Zehner, Matthias; Rohde, Cornelius; Kraehling, Verena; Gellhorn Serra, Michelle; Kreer, Christoph; Kluever, Michael; Sauerhering, Lucie; Schmidt, Jorg; Cai, Zheng; Han, Fei; Young, David; Yang, Guangwei; Widera, Marek; Koch, Manuel; Werner, Anke; Kaemper, Lennart; Becker, Nico; Marlow, Michael S.; Eickmann, Markus; Ciesek, Sandra; Schiele, Felix; Klein, Florian; Becker, Stephan 分享 收藏
Older age, chronic medical conditions and polypharmacy in Himalayan trekkers in Nepal: an epidemiologic survey and case series 尼泊尔喜马拉雅徒步旅行者的年龄较大，慢性病和多重用药: 流行病学调查和病例系列 Keyes, Linda E.; Mather, Luke; Duke, Charles; Regmi, Nirajan; Phelan, Benoit; Pant, Sushil; Starling, Jennifer; McElwee, Matthew; Cole, Devlin; McConnell, Theodore; Paudel, Purshotam; Sallade, T. Douglas; Sheets, Alison; Twillman, David; Young, David S.; Basnyat, Buddha 分享 收藏
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AR36A36.11.1, a monoclonal antibody targeting CD59, enhances complement activity and exhibits potent in vivo efficacy in multiple human cancer models Mak, Baldwin C.; McConkey, Fortunata; Feng, Ningping; O'Reilly, Kevin; Rubinstein, Daniel; Kasprzyk, Philip G.; Hahn, Susan E.; Pereira, Daniel S.; Findlay, Helen; Young, David S. 分享 收藏
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