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P

Prem Khanal

H指数:15

被引数:872

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Kinome-Wide Screening Identifies FAK as a Novel Post-Translational Regulator of PD-L1 Stability and Immune Evasion in Triple-Negative Breast Cancer

激酶组学筛选鉴定FAK为三阴性乳腺癌中PD-L1稳定性和免疫逃逸的新型翻译后调控因子

International Journal of Molecular Sciences 2025, Vol. 26, Page 10108

IF0

2025-10-170

OAAI

Nizubaglustat, a novel GCS and NLGase inhibitor significantly increases survival in a mouse model of GM1 gangliosidosis

MOLECULAR GENETICS AND METABOLISM

IF3.5

2025-02-010

PRE

Characterization of a phenotypically severe animal model for human AB-Variant GM2 gangliosidosis

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2023-11-302

OAAI

A one-step tRNA-CRISPR system for genome-wide genetic interaction mapping in mammalian cells (vol 9, 14499, 2019)

用于哺乳动物细胞全基因组遗传相互作用作图的一步trna-crispr系统 (第9卷，14499，2019)

SCIENTIFIC REPORTS

IF3.9

2021-07-080

OAAI

A one-step tRNA-CRISPR system for genome-wide genetic interaction mapping in mammalian cells

SCIENTIFIC REPORTS

IF3.9

2019-10-108

OAAI

A gain-of-functional screen identifies the Hippo pathway as a central mediator of receptor tyrosine kinases during tumorigenesis

IF7.3

2019-09-0255

PREAI

A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion

IF4.2

2019-08-2037

OAAI

Identification of Prolyl isomerase Pin1 as a novel positive regulator of YAP/TAZ in breast cancer cells

SCIENTIFIC REPORTS

IF3.9

2019-04-2319

OAAI

Screen for immune-related transcriptional targets of the Hippo pathway in human breast cancer cells

CANCER RESEARCH

IF16.6

2018-07-010

PRE

Identification of Cdk1-LATS-Pin1 as a Novel Signaling Axis in Anti-tubulin Drug Response of Cancer Cells

MOLECULAR CANCER RESEARCH

IF4.7

2018-05-3120

OAAI

The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1

CANCER RESEARCH

IF16.6

2018-03-14220

OAAI

Cysteine residues are essential for dimerization of Hippo pathway components YAP2L and TAZ

SCIENTIFIC REPORTS

IF3.9

2018-02-2213

OAAI

A Hippo-independent pathway modulates YAP-induced resistance of cancer cells to antitubulin drugs

CANCER RESEARCH

IF16.6

2014-10-010

PRE

YAP-Induced Resistance of Cancer Cells to Antitubulin Drugs Is Modulated by a Hippo-Independent Pathway

CANCER RESEARCH

IF16.6

2014-08-1386

OAAI

COT Phosphorylates Prolyl-Isomerase Pin1 to Promote Tumorigenesis in Breast Cancer

MOLECULAR CARCINOGENESIS

IF3.2

2013-11-2229

PREAI

Prolyl isomerase Pin1 negatively regulates the stability of SUV39H1 to promote tumorigenesis in breast cancer

脯氨酰异构酶Pin1负调控SUV39H1的稳定性促进乳腺癌的发生

IF4.2

2013-08-0932

OA

The Prolyl Isomerase Pin1 Interacts With and Downregulates the Activity of AMPK Leading to Induction of Tumorigenicity of Hepatocarcinoma Cells

MOLECULAR CARCINOGENESIS

IF3.2

2012-04-3015

PREAI

Proyl isomerase Pin1 facilitates ubiquitin-mediated degradation of cyclin-dependent kinase 10 to induce tamoxifen resistance in breast cancer cells

IF7.3

2011-12-1246

OAAI

5′-Nitro-Indirubinoxime Inhibits Epidermal Growth Factor- and Phorbol Ester-Induced AP-1 Activity and Cell Transformation Through Inhibition of Phosphorylation of Pin1

MOLECULAR CARCINOGENESIS

IF3.2

2011-03-1113

PREAI

The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer (vol 285, pg 23829, 2010)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-03-010

OAAI