Jacques P. Tremblay - Publications, H-index & Citations

Jacques P. Tremblay

département de médecine moléculaire

57H指数

416论文数

1.3W被引数

收录论文 23

发表时间

Molecular characterization of a new R1925X point mutation mouse model for dysferlinopathy 一个新的肌芬林蛋白病R1925X点突变小鼠模型的分子特征分析

Genes & Diseases

IF9.4

2025-10-20

OAAI

Camille Bouchard; Louis Despax; Joël Rousseau; Jacques P. Tremblay

Correction: Harnessing the promises of cell therapy; gene therapy; and regenerative medicine in Québec; Canada 更正：利用细胞疗法、基因疗法和再生医学在魁北克省加拿大的潜力。

Frontiers in Medicine

IF3

2025-10-17

OAAI

Jean-Sébastien Delisle; Diane Fournier; Kim Santerre; Samuel Rochette; Ma'n H. Zawati; Maude Dumont-Lagacé; Simon Turcotte; Jason Robert Guertin; Patrick Vermette; Jacques P. Tremblay; Maxime Parisotto; Christian Beauséjour; Jean-François Gélinas; Louisa Petropoulos; Natasha Kekre; Stéphanie Michaud; Mélanie Dieudé

Universal Prime Editing Therapeutic Strategy for RyR1-Related Myopathies: A Protective Mutation Rescues Leaky RyR1 Channel RyR1相关肌病的高通量质粒编辑治疗策略：一种保护性突变可修复泄漏的RyR1通道

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-03-21

OAAI

Godbout, Kelly; Dugas, Mathieu; Reiken, Steven R.; Ramezani, Sina; Falle, Alexia; Rousseau, Joel; Wronska, Anetta E.; Lamothe, Gabriel; Canet, Geoffrey; Lu, Yaoyao; Planel, Emmanuel; Marks, Andrew R.; Tremblay, Jacques P.

Emerging Perspectives on Prime Editor Delivery to the Brain 关于Prime编辑器传递到大脑的新兴观点

PHARMACEUTICALS

IF4.8

2024-06-11

OAAI

Bendavid, Eli; Ramezanian, Sina; Lu, Yaoyao; Rousseau, Joel; Schroeder, Avi; Lavertu, Marc; Tremblay, Jacques P.

Human MuStem cells are competent to fuse with nonhuman primate myofibers in a clinically relevant transplantation context: A proof-of-concept study

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

IF3

2024-05-16

PREAI

Charrier, Marine; Leroux, Isabelle; Pichon, Julien; Schleder, Cindy; Larcher, Thibaut; Hamel, Antoine; Magot, Armelle; Pereon, Yann; Lamirault, Guillaume; Tremblay, Jacques P.; Skuk, Daniel; Rouger, Karl

Successful Correction by Prime Editing of a Mutation in the RYR1 Gene Responsible for a Myopathy 通过对负责肌病的RYR1基因突变进行初步编辑，成功进行了校正

CELLS

IF5.2

2023-12-22

OAAI

Godbout, Kelly; Rousseau, Joel; Tremblay, Jacques P.

CRISPR-Cas9 delivery strategies with engineered extracellular vesicles 工程细胞外囊泡的CRISPR-Cas9递送策略

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2023-12-01

OAAI

Lu, Yaoyao; Godbout, Kelly; Lamothe, Gabriel; Tremblay, Jacques P.

Development of a gene therapy treatment for RYR1-related diseases using prime editing

JOURNAL OF THE NEUROLOGICAL SCIENCES

IF3.2

2023-12-01

PREAI

Godbout, Kelly; Rousseau, Joel; Tremblay, Jacques

Portrait of Dysferlinopathy: Diagnosis and Development of Therapy Dysferlinopathy的肖像: 治疗的诊断和发展

JOURNAL OF CLINICAL MEDICINE

IF2.9

2023-09-16

OAAI

Bouchard, Camille; Tremblay, Jacques P.

Rapid and Technically Simple Detection of SARS-CoV-2 Variants Using CRISPR Cas12 and Cas13

CRISPR JOURNAL

IF4

2023-08-01

PREAI

Lamothe, Gabriel; Carbonneau, Julie; Beauparlant, Charles Joly; Vincent, Thierry; Quessy, Patrik; Guedon, Anthony; Kobinger, Gary; Lemay, Jean-Francois; Boivin, Guy; Droit, Arnaud; Turgeon, Nathalie; Tremblay, Jacques P.

Limb-Girdle Muscular Dystrophies Classification and Therapies 肢带型肌营养不良的分类与治疗

JOURNAL OF CLINICAL MEDICINE

IF2.9

2023-07-19

OAAI

Bouchard, Camille; Tremblay, Jacques P.

Prime Editing for Human Gene Therapy: Where Are We Now?人类基因治疗的主要编辑: 我们现在在哪里？

CELLS

IF5.2

2023-02-07

OAAI

Godbout, Kelly; Tremblay, Jacques P.

Prime editing optimized RTT permits the correction of the c.8713C>T mutation in DMD gene Prime编辑优化的RTT允许校正DMD基因中的c.8713C>T突变

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2022-12-01

OAAI

Mbakam, Cedric Happi; Rousseau, Joel; Lu, Yaoyao; Bigot, Anne; Mamchaoui, Kamel; Mouly, Vincent; Tremblay, Jacques P.

Delivery of RNAs to Specific Organs by Lipid Nanoparticles for Gene Therapy 通过脂质纳米颗粒将rna递送至特定器官用于基因治疗

PHARMACEUTICS

IF5.5

2022-10-07

OAAI

Godbout, Kelly; Tremblay, Jacques P.

Allele-Specific Inactivation of an Autosomal Dominant Epidermolysis Bullosa Simplex Mutation Using CRISPR-Cas9

CRISPR JOURNAL

IF4

2022-08-01

PREAI

Bchetnia, Mbarka; Dionne Gagne, Rebecca; Powell, Julie; Morin, Charles; McCuaig, Catherine; Duperee, Audrey; Germain, Lucie; Tremblay, Jacques P.; Laprise, Catherine

Serum extracellular vesicles for delivery of CRISPR-CAS9 ribonucleoproteins to modify the dystrophin gene 用于递送CRISPR-CAS9核糖核蛋白以修饰肌营养不良蛋白基因的血清细胞外囊泡

MOLECULAR THERAPY

IF12

2022-07-01

OAAI

Majeau, Nathalie; Fortin-Archambault, Annabelle; Gerard, Catherine; Rousseau, Joel; Yameogo, Pouire; Tremblay, Jacques P.

CRISPR-Cas9 Gene Therapy for Duchenne Muscular Dystrophy 杜氏肌营养不良症的CRISPR-Cas9基因治疗

NEUROTHERAPEUTICS

IF6.9

2022-04-01

OAAI

Mbakam, Cedric Happi; Lamothe, Gabriel; Tremblay, Guillaume; Tremblay, Jacques P.

Insertion of the Icelandic Mutation (A673T) by Prime Editing: A Potential Preventive Treatment for Familial and Sporadic Alzheimer's Disease 通过Prime编辑插入冰岛突变 (A673T): 家族性和散发性阿尔茨海默氏病的潜在预防性治疗

CRISPR JOURNAL

IF4

2022-02-01

OAAI

Tremblay, Guillaume; Rousseau, Joel; Mbakam, Cedric Happi; Tremblay, Jacques P.

Base editing strategy for insertion of the A673T mutation in the APP gene to prevent the development of AD in vitro 在APP基因中插入A673T突变的碱基编辑策略，以防止体外AD的发展

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2021-06-01

OAAI

Guyon, Antoine; Rousseau, Joel; Begin, Francis-Gabriel; Bertin, Tom; Lamothe, Gabriel; Tremblay, Jacques P.

Current Clinical Applications of In Vivo Gene Therapy with AAVs AAVs体内基因治疗的临床应用现状

MOLECULAR THERAPY

IF12

2021-02-01

452

OAAI

Mendell, Jerry R.; Al-Zaidy, Samiah A.; Rodino-Klapac, Louise R.; Goodspeed, Kimberly; Gray, Steven J.; Kay, Christine N.; Boye, Sanford L.; Boye, Shannon E.; George, Lindsey A.; Salabarria, Stephanie; Corti, Manuela; Byrne, Barry J.; Tremblay, Jacques P.

研究方向