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L

L. Govindasamy

State University System of Florida

39H指数
173论文数
5.3K被引数
收录论文 30
发表时间
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Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function
errMOLECULAR THERAPY
IF12
err2018-12-01
err91
errOAAI
errGiles, April R.; Sims, Joshua J.; Turner, Kevin B.; Govindasamy, Lakshmanan; Alvira, Mauricio R.; Lock, Martin; Wilson, James M.
err分享
err收藏
Mapping an Adeno-associated Virus 9-Specific Neutralizing Epitope To Develop Next-Generation Gene Delivery Vectors
errJOURNAL OF VIROLOGY
IF3.8
err2018-10-15
err43
errOAAI
errGiles, April R.; Govindasamy, Lakshmanan; Somanathan, Suryanarayan; Wilson, James M.
err分享
err收藏
Mapping the Humoral Immune Response to AAV by Molecular Docking and Cryo-Electron Microscopy for the Design of Next-Generation AAV Vectors
errMOLECULAR THERAPY
IF12
err2016-05-01
err0
errOAAI
errGiles, April R.; Govindasamy, Lakshmanan; Calcedo, Roberto; Tretiakova, Anna; Boyd, Surina; Qin, Qiuyue; Schneider, Mark; Wilson, James M.
err分享
err收藏
Vector Design Tour de Force: Integrating Combinatorial and Rational Approaches to Derive Novel Adeno-associated Virus Variants
errMOLECULAR THERAPY
IF12
err2014-11-01
err88
errOAAI
errMarsic, Damien; Govindasamy, Lakshmanan; Currlin, Seth; Markusic, David M.; Tseng, Yu-Shan; Herzog, Roland W.; Agbandje-McKenna, Mavis; Zolotukhin, Sergei
err分享
err收藏
Structural Insights into Adeno-Associated Virus Serotype 5
errJOURNAL OF VIROLOGY
IF3.8
err2013-10-15
err102
errOAAI
errGovindasamy, Lakshmanan; DiMattia, Michael A.; Gurda, Brittney L.; Halder, Sujata; McKenna, Robert; Chiorini, John A.; Muzyczka, Nicholas; Zolotukhin, Sergei; Agbandje-McKenna, Mavis
err分享
err收藏
Structural Characterization of H-1 Parvovirus: Comparison of Infectious Virions to Empty Capsids
errJOURNAL OF VIROLOGY
IF3.8
err2013-05-01
err31
errOAAI
errHalder, Sujata; Nam, Hyun-Joo; Govindasamy, Lakshmanan; Vogel, Michele; Dinsart, Christiane; Salome, Nathalie; McKenna, Robert; Agbandje-McKenna, Mavis
err分享
err收藏
Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector使用翻译优化的AAV载体对杜氏肌营养不良症进行1期基因治疗
errMOLECULAR THERAPY
IF12
err2012-02-01
err400
errOAAI
errBowles, Dawn E.; McPhee, Scott W. J.; Li, Chengwen; Gray, Steven J.; Samulski, Jade J.; Camp, Angelique S.; Li, Juan; Wang, Bing; Monahan, Paul E.; Rabinowitz, Joseph E.; Grieger, Joshua C.; Govindasamy, Lakshmanan; Agbandje-McKenna, Mavis; Xiao, Xiao; Samulski, R. Jude
err分享
err收藏
Characterization of novel canine bocaviruses and their association with respiratory disease
errJOURNAL OF GENERAL VIROLOGY
IF4.3
err2012-02-01
err78
errOAAI
errKapoor, Amit; Mehta, Natasha; Dubovi, Edward J.; Simmonds, Peter; Govindasamy, Lakshmanan; Medina, Jan L.; Street, Craig; Shields, Shelly; Lipkin, W. Ian
err分享
err收藏
Engineering Liver-detargeted AAV9 Vectors for Cardiac and Musculoskeletal Gene Transfer
errMOLECULAR THERAPY
IF12
err2011-06-01
err250
errOAAI
errPulicherla, Nagesh; Shen, Shen; Yadav, Swati; Debbink, Kari; Govindasamy, Lakshmanan; Agbandje-McKenna, Mavis; Asokan, Aravind
err分享
err收藏
Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina
errMOLECULAR THERAPY
IF12
err2011-02-01
err257
errOAAI
errPetrs-Silva, Hilda; Dinculescu, Astra; Li, Qiuhong; Deng, Wen-Tao; Pang, Ji-jing; Min, Seok-Hong; Chiodo, Vince; Neeley, Andy W.; Govindasamy, Lakshmanan; Bennett, Antonette; Agbandje-McKenna, Mavis; Zhong, Li; Li, Baozheng; Jayandharan, Giridhara R.; Srivastava, Arun; Lewin, Alfred S.; Hauswirth, William W.
err分享
err收藏
Structural Characterization of the Dual Glycan Binding Adeno-Associated Virus Serotype 6双聚糖结合腺相关病毒血清型6的结构表征
errJOURNAL OF VIROLOGY
IF3.8
err2010-12-15
err165
errOAAI
errNg, Robert; Govindasamy, Lakshmanan; Gurda, Brittney L.; McKenna, Robert; Kozyreva, Olga G.; Samulski, R. Jude; Parent, Kristin N.; Baker, Timothy S.; Agbandje-McKenna, Mavis
err分享
err收藏
Structure-Function Correlation of G6, a Novel Small Molecule Inhibitor of Jak2 INDISPENSABILITY OF THE STILBENOID CORE
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2010-10-01
err18
errOAAI
errMajumder, Anurima; Govindasamy, Lakshmanan; Magis, Andrew; Kiss, Robert; Polgar, Timea; Baskin, Rebekah; Allan, Robert W.; Agbandje-McKenna, Mavis; Reuther, Gary W.; Keseru, Gyoergy M.; Bisht, Kirpal S.; Sayeski, Peter P.
err分享
err收藏
Heparin binding induces conformational changes in Adeno-associated virus serotype 2
errJOURNAL OF STRUCTURAL BIOLOGY
IF5.1
err2009-03-01
err131
errOAAI
errLevy, Hazel C.; Bowman, Valorie D.; Govindasamy, Lakshmanan; McKenna, Robert; Nash, Kevin; Warrington, Kenneth; Chen, Weijun; Muzyczka, Nicholas; Yan, Xiaodong; Baker, Timothy S.; Agbandje-McKenna, Mavis
err分享
err收藏
Molecular characterization of the heparin-dependent transduction domain on the capsid of a novel adeno-associated virus isolate, AAV(VR-942)
errJOURNAL OF VIROLOGY
IF3.8
err2008-09-01
err67
errOAAI
errSchmidt, Michael; Govindasamy, Lakshmanan; Afione, Sandra; Kaludov, Nick; Agbandje-McKenna, Mavis; Chiorini, John A.
err分享
err收藏
Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2008-06-03
err604
errOAAI
errZhong, Li; Li, Baozheng; Mah, Cathryn S.; Govindasamy, Lakshmanan; Agbandje-McKenna, Mavis; Cooper, Mario; Herzog, Roland W.; Zolotukhin, Irene; Warrington, Kenneth H., Jr.; Aken, Kirsten A. Weigel-Van; Hobbs, Jacqueline A.; Zolotukhin, Sergei; Muzyczka, Nicholas; Srivastava, Arun
err分享
err收藏
Surface loop dynamics in adeno-associated virus capsid assembly
errJOURNAL OF VIROLOGY
IF3.8
err2008-06-01
err74
errOAAI
errDiPritmio, Nina; Asokan, Aravind; Govindasamy, Lakshmanan; Agbandje-McKenna, Mavis; Samulski, R. Jude
err分享
err收藏
Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2008-01-24
err14
PREAI
errClemente, Jose C.; Robbins, Arthur; Grana, Paula; Paleo, M. Rita; Correa, Juan F.; Villaverde, M. Carmen; Sardina, F. Javier; Govindasamy, Lakshmanan; Agbandje-McKenna, Mavis; McKenna, Robert; Dunn, Ben M.; Sussman, Fredy
err分享
err收藏
A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis
errMOLECULAR THERAPY
IF12
err2007-07-01
err171
errOAAI
errZhong, Li; Zhao, Weihong; Wu, Jianqing; Li, Baozheng; Zolotukhin, Sergei; Govindasamy, Lakshmanan; Agbandje-McKenna, Mavis; Srivastava, Arun
err分享
err收藏
Structurally mapping the diverse phenotype of adeno-associated virus serotype 4
errJOURNAL OF VIROLOGY
IF3.8
err2006-12-01
err244
errOAAI
errGovindasamy, Lakshmanan; Padron, Eric; McKenna, Robert; Muzyczka, Nicholas; Kaludov, Nikola; Chiorini, John A.; Agbandje-McKenna, Mavis
err分享
err收藏
Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes
errJOURNAL OF VIROLOGY
IF3.8
err2006-11-01
err271
errOAAI
errWu, Zhijian; Asokan, Aravind; Grieger, Joshua C.; Govindasamy, Lakshmanan; Agbandje-McKenna, Mavis; Samulski, R. Jude
err分享
err收藏

研究方向

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