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H

Hasier Eraña

cic biogune and brta
H指数:19
被引数:1,171

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The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

小鼠朊病毒蛋白中的L108I多态性驱动自发性疾病，并增强非典型和典型朊病毒株的传播。

Brain Pathology
IF6.2
2026-02-090
OAAI
Hasier Eraña; Enric Vidal; Natalia Fernández-Borges; Jorge M. Charco; Carlos M. Díaz-Domínguez; Cristina Sampedro-Torres-Quevedo; Josu Galarza-Ahumada; Eva Fernández-Muñoz; Maitena San-Juan-Ansoleaga; Miguel Ángel Pérez-Castro; Nuno Gonçalves-Anjo; Patricia Piñeiro; Samanta Giler; Nora González-Martín; Nuria L. Lorenzo; Africa Manero-Azua; Guiomar Perez de Nanclares; Mariví Geijo; Manuel A. Sánchez-Martín; Jesús R. Requena; Joaquín Castilla
Overexpression of bank vole PrP(I109) in mice induces a spontaneous atypical prion disease with sex-dependent onset, early NfL elevation, and universal prion strain permissiveness

小鼠中银行田鼠PrP(I109) 的过表达会诱发自发性非典型朊病毒病，具有性别依赖性发作，早期NfL升高和普遍的朊病毒菌株允许性。

Acta Neuropathologica Communications
IF5.7
2026-01-200
OAAI
Hasier Eraña; Enric Vidal; Natalia Fernández-Borges; Jorge M. Charco; Carlos M. Díaz‑Domínguez; Cristina Sampedro-Torres-Quevedo; Maitena San-Juan-Ansoleaga; Eva Fernández-Muñoz; Josu Galarza-Ahumada; Miguel Ángel Pérez-Castro; Nuno Gonçalves-Anjo; Patricia Piñeiro; Laura Pirisinu; Michele Angelo Di Bari; Samanta Giler; Ilaria Raimondi; Juan Carlos Espinosa; Ilaria Vanni; Claudia D’Agostino; Juan Rodríguez-Cuesta; Laura Pasetto; Valentina Bonetto; Nora González-Martín; Susana Teijeira; Wen-Quan Zou; Mariví Geijo; Juan María Torres; Roberto Chiesa; Manuel A. Sánchez‑Martín; Romolo Nonno; Jesús R. Requena; Joaquín Castilla
Effect of primary structural variation on cervid prion protein in flexibility, stability, and spontaneous misfolding propensity

初级结构变异对鹿科动物朊蛋白在柔韧性、稳定性及自发错误折叠倾向的影响

Neurobiology of Disease
IF5.6
2025-06-130
OA
Carlos M. Díaz-Domínguez; Hasier Eraña; Francesca Peccati; Enric Vidal; Jorge M. Charco; Cristina Sampedro-Torres-Quevedo; Miguel A. Pérez-Castro; Nuria L. Lorenzo; Samanta Giler; Glenn C. Telling; Mariví Geijo; Jesús R. Requena; Gonzalo Jiménez-Osés; Joaquín Castilla
Conservation of strain properties of bank vole-adapted chronic wasting disease in the absence of glycosylation and membrane anchoring

缺乏糖基化和膜锚定的条件下，适应田鼠的慢性消耗性疾病的毒株特性得以保持

NEUROBIOLOGY OF DISEASE
IF5.6
2025-06-010
OAAI
Vidal, Enric; Erana, Hasier; Charco, Jorge M.; Lorenzo, Nuria L.; Giler, Samanta; Ordonez, Montserrat; Fernandez-Munoz, Eva; San-Juan-Ansoleaga, Maitena; Telling, Glenn C.; Sanchez-Martin, Manuel A.; Geijo, Marivi; Requena, Jesus R.; Castilla, Joaquin
Cofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions
PLOS PATHOGENS
IF4.9
2025-01-220
OAAI
Perez-Castro, Miguel A.; Erana, Hasier; Vidal, Enric; Charco, Jorge M.; Lorenzo, Nuria L.; Goncalves-Anjo, Nuno; Galarza-Ahumada, Josu; Diaz-Dominguez, Carlos M.; Pineiro, Patricia; Gonzalez-Miranda, Ezequiel; Giler, Samanta; Telling, Glenn; Sanchez-Martin, Manuel A.; Garrido, Joseba; Geijo, Marivi; Requena, Jesus R.; Castilla, Joaquin
Classical BSE dismissed as the cause of CWD in Norwegian red deer despite strain similarities between both prion agents
VETERINARY RESEARCH
IF3.5
2024-05-151
OAAI
Marin-Moreno, Alba; Benestad, Sylvie L.; Barrio, Tomas; Pirisinu, Laura; Espinosa, Juan Carlos; Tran, Linh; Huor, Alvina; Di Bari, Michele Angelo; Erana, Hasier; Maddison, Ben C.; D'Agostino, Claudia; Fernandez-Borges, Natalia; Canoyra, Sara; Jerez-Garrido, Nuria; Castilla, Joaquin; Spiropoulos, John; Bishop, Keith; Gough, Kevin C.; Nonno, Romolo; Vage, Jorn; Andreoletti, Olivier; Torres, Juan Maria
A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions
NATURE COMMUNICATIONS
IF15.7
2024-03-082
OAAI
Erana, Hasier; Sampedro-Torres-Quevedo, Cristina; Charco, Jorge M.; Diaz-Dominguez, Carlos M.; Peccati, Francesca; San-Juan-Ansoleaga, Maitena; Vidal, Enric; Goncalves-Anjo, Nuno; Perez-Castro, Miguel A.; Gonzalez-Miranda, Ezequiel; Pineiro, Patricia; Fernandez-Veiga, Leire; Galarza-Ahumada, Josu; Fernandez-Munoz, Eva; Perez de Nanclares, Guiomar; Telling, Glenn; Geijo, Marivi; Jimenez-Oses, Gonzalo; Castilla, Joaquin
Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation
ACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
2023-09-079
OA
Erana, Hasier; Diaz-Dominguez, Carlos M.; Charco, Jorge M.; Vidal, Enric; Gonzalez-Miranda, Ezequiel; Perez-Castro, Miguel A.; Pineiro, Patricia; Lopez-Moreno, Rafael; Sampedro-Torres-Quevedo, Cristina; Fernandez-Veiga, Leire; Tasis-Galarza, Juan; Lorenzo, Nuria L.; Santini-Santiago, Aileen; Lazaro, Melisa; Garcia-Martinez, Sandra; Goncalves-Anjo, Nuno; San-Juan-Ansoleaga, Maitena; Galarza-Ahumada, Josu; Fernandez-Munoz, Eva; Giler, Samanta; Valle, Mikel; Telling, Glenn C.; Geijo, Marivi; Requena, Jesus R.; Castilla, Joaquin
Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model
ACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
2022-12-134
OA
Vidal, Enric; Sanchez-Martin, Manuel A.; Erana, Hasier; Perez Lazaro, Sonia; Perez-Castro, Miguel A.; Otero, Alicia; Charco, Jorge M.; Marin, Belen; Lopez-Moreno, Rafael; Diaz-Dominguez, Carlos M.; Geijo, Marivi; Ordonez, Montserrat; Cantero, Guillermo; di Bari, Michele; Lorenzo, Nuria L.; Pirisinu, Laura; d'Agostino, Claudia; Maria Torres, Juan; Beringue, Vincent; Telling, Glenn; Badiola, Juan J.; Pumarola, Marti; Bolea, Rosa; Nonno, Romolo; Requena, Jesus R.; Castilla, Joaquin
Homozygous R136S mutation in PRNP gene causes inherited early onset prion disease

PRNP基因纯合R136S突变导致遗传性早发型朊病毒病

ALZHEIMERS RESEARCH & THERAPY
IF7.6
2021-10-188
OAAI
Ximelis, Teresa; Marin-Moreno, Alba; Carlos Espinosa, Juan; Erana, Hasier; Charco, Jorge M.; Hernandez, Isabel; Riveira, Carmen; Alcolea, Daniel; Gonzalez-Roca, Eva; Aldecoa, Iban; Molina-Porcel, Laura; Parchi, Piero; Rossi, Marcello; Castilla, Joaquin; Ruiz-Garcia, Raquel; Gelpi, Ellen; Maria Torres, Juan; Sanchez-Valle, Raquel
Dogs are resistant to prion infection, due to the presence of asparagine at position 163 of their prion protein

由于在其病毒蛋白的163位存在天冬酰胺，因此狗对病毒感染具有抵抗力

FASEB JOURNAL
IF4.2
2020-01-1525
OAAI
Vidal, Enric; Fernandez-Borges, Natalia; Erana, Hasier; Parra, Beatriz; Pintado, Belen; Sanchez-Martin, Manuel A.; Charco, Jorge M.; Ordonez, Montserrat; Perez-Castro, Miguel A.; Pumarola, Marti; Mathiason, Candace K.; Mayoral, Tomas; Castilla, Joaquin

研究方向

暂未获取到该数据
J
Joaquı́n Castilla
H 指数:46论文数:161被引数:8,186
J
Jorge M. Charco
H 指数:15论文数:76被引数:644
E
Enríc Vidal
H 指数:29论文数:143被引数:2,905
N
Natalia Fernández‐Borges
H 指数:28论文数:67被引数:2,116
M
Miguel A. Pérez‐Castro
H 指数:9论文数:25被引数:212
J
Jesús R. Requena
H 指数:29论文数:101被引数:3,712
C
Carlos M. Díaz‐Domínguez
H 指数:8论文数:20被引数:159
M
Manuel Sánchez‐Martín
H 指数:28论文数:142被引数:3,385
M
Mariví Geijó
H 指数:21论文数:49被引数:1,414
G
Glenn C. Telling
H 指数:52论文数:169被引数:1.0万