未登录 Discovery of 9-Cyclopropylethynyl-2-((S)-1-[1,4]dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one (GLPG1205), a Unique GPR84 Negative Allosteric Modulator Undergoing Evaluation in a Phase II Clinical Trial Labeguere, Frederic; Dupont, Sonia; Alvey, Luke; Soulas, Florilene; Newsome, Gregory; Tirera, Amynata; Quenehen, Vanessa; Thi Thu Trang Mai; Deprez, Pierre; Blanque, Roland; Oste, Line; Le Tallec, Sandrine; De Vos, Steve; Hagers, Annick; Vandevelde, Ann; Nelles, Luc; Vandervoort, Nele; Conrath, Katja; Christophe, Thierry; van der Aar, Ellen; Wakselman, Emanuelle; Merciris, Didier; Cottereaux, Celine; da Costa, Cecile; Saniere, Laurent; Clement-Lacroix, Philippe; Jenkins, Laura; Milligan, Graeme; Fletcher, Stephen; Brys, Reginald; Gosmini, Romain 分享 收藏
Discovery and Optimization of an Azetidine Chemical Series As a Free Fatty Acid Receptor 2 (FFA2) Antagonist: From Hit to Clinic Pizzonero, Mathieu; Dupont, Sonia; Babel, Marielle; Beaumont, Stephane; Bienvenu, Natacha; Blanque, Roland; Cherel, Laetitia; Christophe, Thierry; Crescenzi, Benedetta; De Lemos, Elsa; Delerive, Philippe; Deprez, Pierre; De Vos, Steve; Djata, Fatoumata; Fletcher, Stephen; Kopiejewski, Sabrina; L'Ebraly, Christelle; Lefrancois, Jean-Michel; Lavazais, Stephanie; Manioc, Murielle; Nelles, Luc; Oste, Line; Polancec, Denis; Quenehen, Vanessa; Soulas, Florilene; Triballeau, Nicolas; van der Aar, Ellen M.; Vandeghinste, Nick; Wakselman, Emanuelle; Brys, Reginald; Saniere, Laurent 分享 收藏
Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634 Menet, Christel J.; Fletcher, Stephen R.; Van Lommen, Guy; Geney, Raphael; Blanc, Javier; Smits, Koen; Jouannigot, Nolwenn; Deprez, Pierre; van der Aar, Ellen M.; Clement-Lacroix, Philippe; Lepescheux, Lien; Galien, Rene; Vayssiere, Beatrice; Nelles, Luc; Christophe, Thierry; Brys, Reginald; Uhring, Muriel; Ciesieski, Fabrice; Van Rompaey, Luc 分享 收藏
Preclinical Characterization of GLPG0634, a Selective Inhibitor of JAK1, for the Treatment of Inflammatory Diseases Van Rompaey, Luc; Galien, Rene; van der Aar, Ellen M.; Clement-Lacroix, Philippe; Nelles, Luc; Smets, Bart; Lepescheux, Lien; Christophe, Thierry; Conrath, Katja; Vandeghinste, Nick; Vayssiere, Beatrice; De Vos, Steve; Fletcher, Stephen; Brys, Reginald; van 't Klooster, Gerben; Feyen, Jean H. M.; Menet, Christel 分享 收藏
Identification of a 4-(Hydroxymethyl)diarylhydantoin as a Selective Androgen Receptor Modulator Nique, Francois; Hebbe, Severine; Triballeau, Nicolas; Peixoto, Christophe; Lefrancois, Jean-Michel; Jary, Helene; Alvey, Luke; Manioc, Murielle; Housseman, Christopher; Klaassen, Hugo; Van Beeck, Kris; Guedin, Denis; Namour, Florence; Minet, Dominque; Van der Aar, Ellen; Feyen, Jean; Fletcher, Stephen; Blanque, Roland; Robin-Jagerschmidt, Catherine; Deprez, Pierre 分享 收藏
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A new pyridazine series of GABAA α5 ligands van Niel, MB; Wilson, K; Adkins, CH; Atack, JR; Castro, JL; Clarke, DE; Fletcher, S; Gerhard, U; Mackey, MM; Malpas, S; Maubach, K; Newman, R; O'Connor, D; Pillai, GV; Simpson, PB; Thomas, SR; MacLeod, AM 分享 收藏
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