未登录 Sugar Acetonides are a Superior Motif for Addressing the Large, Solvent-Exposed Ribose-33 Pocket of tRNA-Guanine Transglycosylase Movsisyan, Levon D.; Schafer, Elisabeth; Andreas Nguyen; Ehrmann, Frederik R.; Schwab, Anatol; Rossolini, Thomas; Zimmerli, Daniel; Wagner, Bjorn; Daff, Hamina; Heine, Andreas; Klebe, Gerhard; Diederich, Francois 分享 收藏
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Replacement of Water Molecules in a Phosphate Binding Site by Furanoside-Appended lin-Benzoguanine Ligands of tRNA-Guanine Transglycosylase (TGT) Barandun, Luzi J.; Ehrmann, Frederik R.; Zimmerli, Daniel; Immekus, Florian; Giroud, Maude; Gruenenfelder, Claudio; Schweizer, W. Bernd; Bernet, Bruno; Betz, Michael; Heine, Andreas; Klebe, Gerhard; Diederich, Francois 分享 收藏
Selective GlyT1 Inhibitors: Discovery of [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl]-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a Promising Novel Medicine To Treat Schizophrenia Pinard, Emmanuel; Alanine, Alexander; Alberati, Daniela; Bender, Markus; Borroni, Edilio; Bourdeaux, Patrick; Brom, Virginie; Burner, Serge; Fischer, Holger; Hainzl, Dominik; Halm, Remy; Hauser, Nicole; Jolidon, Synese; Lengyel, Judith; Marty, Hans-Peter; Meyer, Thierry; Moreau, Jean-Luc; Mory, Roland; Narquizian, Robert; Nettekoven, Mathias; Norcross, Roger D.; Puellmann, Bernd; Schmid, Philipp; Schmitt, Sebastien; Stalder, Henri; Wermuth, Roger; Wettstein, Joseph G.; Zimmerli, Daniel 分享 收藏
Predicting properties and tuning physicochemical in lead optimization:: Amine basicities Morgenthaler, Martin; Schweizer, Eliane; Hoffmann-Roeder, Ania; Benini, Fausta; Martin, Rainer E.; Jaeschke, Georg; Wagner, Bjoern; Fischer, Holger; Bendels, Stefanie; Zimmerli, Daniel; Schneider, Josef; Diederich, Francois; Kansy, Manfred; Mueller, Klaus 分享 收藏
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