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收藏分享 收藏 分享 收藏 分享 收藏 分享 收藏 2MW4691, a novel CCR8/CTLA-4 bispecific antibody, displays potent anti-tumor efficacy by specifically depeleting tumor-infiltrating Tregs and blocking CTLA-4 signaling on CD8+T cells
Guo, Cuicui; Dai, Xiaodong; Xiong, Xiumei; Liu, Hongqin; Cen, Xiaowei; Wu, Hai; Zhang, Jinchao; Gui, Xun 分享 收藏 Disrupting IL-11/IL-11R signaling by an efficacious anti-IL-11 antibody 9MW3811 enhances T cell tumor infiltration and synergizes with anti-PD-1 therapies in vivoWang, Shuang; Zhang, Chang; Jiao, Shasha; Zeng, Dadi; Wang, Rongjuan; Wang, Min; Lu, Weining; Zheng, Bin; Gui, Xun; Zhang, Jinchao 分享 收藏 Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment用CD47/PD-L1双特异性抗体阻断双重免疫检查点抑制信号用于癌症治疗Wang, Rongjuan; Zhang, Chang; Cao, Yuting; Wang, Junchao; Jiao, Shasha; Zhang, Jiao; Wang, Min; Tang, Peipei; Ouyang, Zijun; Liang, Wenlu; Mao, Yu; Wang, An; Li, Gang; Zhang, Jinchao; Wang, Mingzhu; Wang, Shuang; Gui, Xun 分享 收藏 Blocking LAIR1 signaling in immune cells inhibits tumor development阻断免疫细胞中的LAIR1信号抑制肿瘤发展Xie, Jingjing; Gui, Xun; Deng, Mi; Chen, Heyu; Chen, Yuanzhi; Liu, Xiaoye; Ku, Zhiqiang; Tan, Lingxiao; Huang, Ryan; He, Yubo; Zhang, Bruce; Lewis, Cheryl; Chen, Kenian; Xu, Lin; Xu, Jian; Huang, Tao; Liao, X. Charlene; Zhang, Ningyan; An, Zhiqiang; Zhang, Cheng Cheng 分享 收藏 Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires FcγRIIB and virus-antibody complex with bivalent interactionWang, Shuang; Wang, Junchao; Yu, Xiaojuan; Jiang, Wen; Chen, Shuo; Wang, Rongjuan; Wang, Mingzhu; Jiao, Shasha; Yang, Yingying; Wang, Wenbo; Chen, Huilin; Chen, Ben; Gu, Chunying; Liu, Chuang; Wang, An; Wang, Min; Li, Gang; Guo, Cuicui; Liu, Datao; Zhang, Jinchao; Zhang, Min; Wang, Lan; Gui, Xun 分享 收藏 LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2-cFLIP-NF-κB signaling axisLILRB3通过TRAF2-cFLIP-NF-κB信号轴支持急性髓细胞白血病的发展并调节T细胞抗肿瘤免疫反应Wu, Guojin; Xu, Yixiang; Schultz, Robbie D.; Chen, Heyu; Xie, Jingjing; Deng, Mi; Liu, Xiaoye; Gui, Xun; John, Samuel; Lu, Zhigang; Arase, Hisashi; Zhang, Ningyan; An, Zhiqiang; Zhang, Cheng Cheng 分享 收藏 ANTAGONISTIC ANTIBODIES TARGETING LAIR1 ENHANCE T LYMPHOCYTE ACTIVATION AND PROMOTE INFLAMMATORY PHENOTYPES IN MYELOID CELLSHuang, Tao; Bonnans, Caroline; Costa, Maria Jose; Tabrizi, Azita; Ma, Jing-Tyan; Xie, Jingjing; Chen, Heyu; Hong, Kyu; McCutcheon, Krista; Stafford, Ryan; Tian, Hongyu; Zhang, Cheng Cheng; Gui, Xun; Zhang, Ningyan; An, Zhiqiang; Liao, X. Charlene; Song, An 分享 收藏 Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV对SARS-CoV-2和传染性非典型肺炎具有交叉中和活性的人单克隆抗体MW06的表征Jiang, Wen; Wang, Junchao; Jiao, Shasha; Gu, Chenjian; Xu, Wei; Chen, Ben; Wang, Rongjuan; Chen, Huilin; Xie, Youhua; Wang, An; Li, Gang; Zeng, Dadi; Zhang, Jinchao; Zhang, Min; Wang, Shuang; Wang, Mingzhu; Gui, Xun 分享 收藏 Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitmentShan, Zhao; Li, Leike; Atkins, Constance Lynn; Wang, Meng; Wen, Yankai; Jeong, Jongmin; Moreno, Nicolas F.; Feng, Dechun; Gui, Xun; Zhang, Ningyan; Lee, Chun Geun; Elias, Jack A.; Lee, William M.; Gao, Bin; Lam, Fong Wilson; An, Zhiqiang; Ju, Cynthia 分享 收藏 Characterization of neutralizing antibody with prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus monkeysWang, Shuang; Peng, Yun; Wang, Rongjuan; Jiao, Shasha; Wang, Min; Huang, Weijin; Shan, Chao; Jiang, Wen; Li, Zepeng; Gu, Chunying; Chen, Ben; Hu, Xue; Yao, Yanfeng; Min, Juan; Zhang, Huajun; Chen, Ying; Gao, Ge; Tang, Peipei; Li, Gang; Wang, An; Wang, Lan; Zhang, Jinchao; Chen, Shuo; Gui, Xun; Yuan, Zhiming; Liu, Datao 分享 收藏 分享 收藏 Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells拮抗anti-LILRB1单克隆抗体调节自然杀伤细胞的抗肿瘤功能Chen, Heyu; Chen, Yuanzhi; Deng, Mi; John, Samuel; Gui, Xun; Kansagra, Ankit; Chen, Weina; Kim, Jaehyup; Lewis, Cheryl; Wu, Guojin; Xie, Jingjing; Zhang, Lingbo; Huang, Ryan; Liu, Xiaoye; Arase, Hisashi; Huang, Yang; Yu, Hai; Luo, Wenxin; Xia, Ningshao; Zhang, Ningyan; An, Zhiqiang; Zhang, Cheng Cheng 分享 收藏 Identification of adipocyte plasma membrane-associated protein as a novel modulator of human cytomegalovirus infectionYe, Xiaohua; Gui, Xun; Freed, Daniel C.; Ku, Zhiqiang; Li, Leike; Chen, Yuanzhi; Xiong, Wei; Fan, Xuejun; Su, Hang; He, Xi; Rustandi, Richard R.; Loughney, John W.; Ma, Ningning; Espeseth, Amy S.; Liu, Jian; Zhu, Hua; Wang, Dai; Zhang, Ningyan; Fu, Tong-Ming; An, Zhiqiang 分享 收藏 分享 收藏 A Novel Anti-LILRB4 CAR-T Cell for the Treatment of Monocytic AML用于治疗单核细胞AML的新型Anti-LILRB4 car-t细胞John, Samuel; Chen, Heyu; Deng, Mi; Gui, Xun; Wu, Guojin; Chen, Weina; Li, Zunling; Zhang, Ningyan; An, Zhiqiang; Zhang, Cheng Cheng 分享 收藏 
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