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T

Toshitha Kannan

The Wistar Institute
H指数:12
被引数:760

个人简介

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教育背景

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工作经历

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荣誉奖项

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Personalized targeting of BCL2 family proteins overcomes acquired resistance to BRAF-MEK inhibitors in preclinical melanoma

针对BCL2家族蛋白的个性化靶向策略可克服BRAF-MEK抑制剂在黑色素瘤模型中的获得性耐药

Nature Communications
IF15.7
2026-06-260
OAAI
Vashisht Gopal Y.N.; Evelyn de Groot; Kaley Loftin; Barbara Knighton; Debora Ledesma; Courtney Hudgens; Diana Shamsutdinova; Mehboob Ali; Zhenlin Ju; Min Xiao; Toshitha Kannan; Gregory Fontenot; Michael S. Nakazawa; Monzy Thomas; Khalida Wani; Clifford Stephan; Phyu P. Aung; Lawrence N. Kwong; Janos Roszik; Rehan Akbani; Andrew Kossenkov; Vito W. Rebecca; Ryan J. Sullivan; Meenhard Herlyn; Michael A. Davies
Myeloid activation clears ascites and reveals IL27-dependent regression of metastatic ovarian cancer (vol 221, e20231967, 2024)

髓系细胞活化清除腹水并揭示IL27依赖性的转移性卵巢癌消退（vol 221, e20231967, 2024）

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2025-03-110
OA
Murphy, Brennah; Miyamoto, Taito; Manning, Bryan S.; Mirji, Gauri; Ugolini, Alessio; Kannan, Toshitha; Hamada, Kohei; Zhu, Yanfang P.; Claiborne, Daniel T.; Huang, Lu; Zhang, Rugang; Nefedova, Yulia; Kossenkov, Andrew; Veglia, Filippo; Shinde, Rahul; Zhang, Nan
Multiple sclerosis patient-derived spontaneous B cells have distinct EBV and host gene expression profiles in active disease
Nature Microbiology
IF19.4
2024-05-280
PRE
Samantha S. Soldan; Chenhe Su; Maria Chiara Monaco; Leena Yoon; Toshitha Kannan; Urvi Zankharia; Rishi J. Patel; Jayaraju Dheekollu; Olga Vladimirova; Jack W. Dowling; Simon Thebault; Natalie Brown; Annaliese Clauze; Frances Andrada; Andries Feder; Paul J. Planet; Andrew Kossenkov; Daniel E. Schäffer; Joan Ohayon; Noam Auslander; Steven Jacobson; Paul M. Lieberman
Immunoglobulin G N-glycan markers of accelerated biological aging during chronic HIV infection
NATURE COMMUNICATIONS
IF15.7
2024-04-102
OAAI
Giron, Leila B.; Liu, Qin; Adeniji, Opeyemi S.; Yin, Xiangfan; Kannan, Toshitha; Ding, Jianyi; Lu, David Y.; Langan, Susan; Zhang, Jinbing; Azevedo, Joao L. L. C.; Li, Shuk Hang; Shalygin, Sergei; Azadi, Parastoo; Hanna, David B.; Ofotokun, Igho; Lazar, Jason; Fischl, Margaret A.; Haberlen, Sabina; Macatangay, Bernard; Adimora, Adaora A.; Jamieson, Beth D.; Rinaldo, Charles; Merenstein, Daniel; Roan, Nadia R.; Kutsch, Olaf; Gange, Stephen; Wolinsky, Steven M.; Witt, Mallory D.; Post, Wendy S.; Kossenkov, Andrew; Landay, Alan L.; Frank, Ian; Tien, Phyllis C.; Gross, Robert; Brown, Todd T.; Abdel-Mohsen, Mohamed
Distinct intestinal microbial signatures linked to accelerated systemic and intestinal biological aging

与加速全身和肠道生物衰老相关的独特肠道微生物特征

MICROBIOME
IF12.7
2024-02-224
OAAI
Singh, Shalini; Giron, Leila B.; Shaikh, Maliha W.; Shankaran, Shivanjali; Engen, Phillip A.; Bogin, Zlata R.; Bambi, Simona A.; Goldman, Aaron R.; Azevedo, Joao L. L. C.; Orgaz, Lorena; de Pedro, Nuria; Gonzalez, Patricia; Giera, Martin; Verhoeven, Aswin; Sanchez-Lopez, Elena; Pandrea, Ivona; Kannan, Toshitha; Tanes, Ceylan E.; Bittinger, Kyle; Landay, Alan L.; Corley, Michael J.; Keshavarzian, Ali; Abdel-Mohsen, Mohamed
Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer

乙酸盐通过增强T细胞效应子功能和增强乳腺癌的抗肿瘤免疫力而充当代谢免疫调节剂

NATURE CANCER
IF28.5
2023-09-1825
OA
Miller, Katelyn D.; O'Connor, Seamus; Pniewski, Katherine A.; Kannan, Toshitha; Acosta, Reyes; Mirji, Gauri; Papp, Sara; Hulse, Michael; Mukha, Dzmitry; Hlavaty, Sabina I.; Salcido, Kelsey N.; Bertolazzi, Fabrizio; Srikanth, Yellamelli V. V.; Zhao, Steven; Wellen, Kathryn E.; Shinde, Rahul S.; Claiborne, Daniel T.; Kossenkov, Andrew; Salvino, Joseph M.; Schug, Zachary T.
An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression
CANCER DISCOVERY
IF33.3
2023-05-049
OAAI
Indeglia, Alexandra; Leung, Jessica C.; Miller, Sven A.; Leu, Julia I-Ju; Dougherty, James F.; Clarke, Nicole L.; Kirven, Nicole A.; Shao, Chunlei; Ke, Lei; Lovell, Scott; Barnoud, Thibaut; Lu, David Y.; Lin, Cindy; Kannan, Toshitha; Battaile, Kevin P.; Yang, Tyler Hong Loong; Batista Oliva, Isabela; Claiborne, Daniel T.; Vogel, Peter; Liu, Lijun; Liu, Qin; Nefedova, Yulia; Cassel, Joel; Auslander, Noam; Kossenkov, Andrew V.; Karanicolas, John; Murphy, Maureen E.
Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge
FRONTIERS IN IMMUNOLOGY
IF5.9
2023-03-144
OAAI
Gary, Ebony N.; Tursi, Nicholas J.; Warner, Bryce M.; Cuismano, Gina; Connors, Jennifer; Parzych, Elizabeth M.; Griffin, Bryan D.; Bell, Matthew R.; Ali, Ali R.; Frase, Drew; Hojecki, Casey E.; Canziani, Gabriela A.; Chaiken, Irwin; Kannan, Toshitha; Moffat, Estella; Embury-Hyatt, Carissa; Wooton, Sarah K.; Kossenkov, Andrew; Patel, Ami; Kobasa, Darwyn; Kutzler, Michele A.; Haddad, Elias K.; Weiner, David B.
The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer

微生物组衍生的代谢物TMAO驱动免疫激活并增强对胰腺癌免疫检查点阻断的反应

SCIENCE IMMUNOLOGY
IF16.3
2022-09-30134
OA
Mirji, Gauri; Worth, Alison; Bhat, Sajad Ahmad; El Sayed, Mohamed; Kannan, Toshitha; Goldman, Aaron R.; Tang, Hsin-Yao; Liu, Qin; Auslander, Noam; Dang, Chi, V; Abdel-Mohsen, Mohamed; Kossenkov, Andrew; Stanger, Ben Z.; Shinde, Rahul S.

研究方向

暂未获取到该数据
A
Andrew V. Kossenkov
H 指数:72论文数:804被引数:1.8万
D
Daniel T. Claiborne
H 指数:17论文数:147被引数:1,314
M
Mohamed Abdel‐Mohsen
H 指数:41论文数:174被引数:6,222
Y
Yulia Nefedova
H 指数:36论文数:207被引数:1.0万
Rugang Zhang 封面图
Rugang Zhang
H 指数:61论文数:501被引数:1.3万
R
Rahul Shinde
H 指数:18论文数:82被引数:2,862
G
Gauri Mirji
H 指数:5论文数:57被引数:497
T
Taito Miyamoto
H 指数:17论文数:116被引数:1,195
L
Leila B. Giron
H 指数:26论文数:92被引数:1,957
Q
Qin Liu
H 指数:72论文数:976被引数:2.1万