Maria Regina D’Império Lima

instituto de imunologia

36H指数

151论文数

3.9K被引数

收录论文 47

发表时间

CD39 regulates P2RX7-mediated lung necrotic lesions in severe experimental tuberculosis CD39调控P2RX7介导的严重实验性结核病中的肺坏死病灶

Mucosal Immunology

IF7.6

2026-03-14

OAAI

Gislane Almeida-Santos; Igor Santiago-Carvalho; Fabrício Moreira Almeida; Caio César Barbosa Bomfim; Juan Carlo Santos e Silva; Deborah Giovanna Cantarini; Camila Ramos Silva; Martha Simões Ribeiro; Rogério Silva do Nascimento; Bruna de Gois Macedo; Paulo Henrique Lisboa Raeder; Joaquim Teixeira-Xavier Junior; José Maria Alvarez; Mario Hiroyuki Hirata; Robson Coutinho-Silva; Simon C. Robson; Eduardo Pinheiro Amaral; Elena Lasunskaia; Maria Regina D’Império Lima

P2RX7 regulates lung immune responses to allergens in a sensitization route-dependent way

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

de Gois Macedo, Bruna; Santiago-Carvalho, Igor; Salgado, Caio Loureiro; D'imperio Lima, Maria Regina; Borges da Silva, Henrique

Enhancing lung immunity against COVID-19: the role of ATP in TRM cell generation

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Pinheiro Cione, Marcos Vinicios; Santiago-Carvalho, Igor; Barros Manhaes, Luciana dos Santos; Xavier Freitas, Rodrigo Jose Rocha; Silva do Nascimento, Rogerio; Fongaro Botosso, Viviane; Sa Guimaraes, Ana Marcia; Borges da Silva, Henrique; Maria Alvarez Mosig, Jose; D'Imperio Lima, Maria Regina

Increased macrophages contribute to thyroid hormone-induced cardiac alterations in mice 巨噬细胞增多有助于甲状腺激素诱导的小鼠心脏改变

ACTA PHYSIOLOGICA

IF5.6

2025-02-07

PREAI

Senger, N; de Almeida-Santos, G; Cerri, GC; Mota, JS; Parletta, AC; Vieira-Junior, DN; Xavier, JT Jr; do Nascimento, RS; de Souza, DCDR; Irigoyen, MCC; Diniz, GP; Mosig, JMA; Kuhn, TC; Leuschner, F; Lima, MRD; Barreto-Chaves, MLM

T cell-specific P2RX7 favors lung parenchymal CD4+T cell accumulation in response to severe lung infections

JOURNAL OF IMMUNOLOGY

IF3.4

2024-05-01

OAAI

Santiago-Carvalho, Igor; Almeida-Santos, Gislane; Macedo, Bruna De Gois; Barbosa-Bomfim, Caio Cesar; Almeida, Fabricio Moreira; Cione, Marcos Vinicius; Lassounskaia, Elena; D'Imperio-Lima, Maria Regina; da Silva, Henrique Borges

T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections

CELL REPORTS

IF6.9

2023-11-01

OAAI

Santiago-Carvalho, Igor; Almeida-Santos, Gislane; Macedo, Bruna Gois; Barbosa-Bomfim, Caio Cesar; Almeida, Fabricio Moreira; Cione, Marcos Vinicios Pinheiro; Vardam-Kaur, Trupti; Masuda, Mia; Van Dijk, Sarah; Melo, Bruno Marcel; do Nascimento, Rogerio Silva; Souza, Rebeka da Conceicao; Peixoto-Rangel, Alba Lucinia; Coutinho-Silva, Robson; Hirata, Mario Hiroyuki; Alves-Filho, Jose Carlos; Alvarez, Jose Maria; Lassounskaia, Elena; da Silva, Henrique Borges; D'Imperio-Lima, Maria Regina

Oral exposure to Escherichia coli toxin protects against lung allergen-induced inflammation

JOURNAL OF IMMUNOLOGY

IF3.4

2023-05-01

OAAI

Salgado, Caio Loureiro; Ayupe, Marina Cacador; Rodrigues, Juliana Falcao; Silva, Luisa Menezes; Oliveira, Bernardo De Castro; Moreira, Francielly; Goncalves, Leonardo Mandu; da Silva, Guilherme William; Zamame Ramirez, Jofer Andree; De Souza Ferreira, Luis Carlos; D'imperio-Lima, Maria Regina; da Silva, Henrique Borges; da Fonseca, Denise Morais

P2RX7 signaling drives the differentiation of Th1 cells through metabolic reprogramming for aerobic glycolysis P2RX7信号通过代谢重编程促进有氧糖酵解驱动Th1细胞分化

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-03-13

OAAI

Salles, Erika Machado de; Raeder, Paulo Lisboa; Angeli, Claudia Blanes; Santiago, Veronica Feijoli; de Souza, Cristiane Naffah; Ramalho, Theresa; Camara, Niels Olsen Saraiva; Palmisano, Giuseppe; alvarez, Jose Maria; D'Imperio Lima, Maria Regina

LAMP-1 Chimeric to HIV-1 p55Gag in the Immunization of Neonate Mice Induces an Early Germinal Center Formation and AID Expression

VACCINES

IF3.4

2022-08-03

OAAI

Teixeira, Franciane Mouradian Emidio; Oliveira, Luana de Mendonca; Pietrobon, Anna Julia; de Salles, Erika Machado; D'Imperio Lima, Maria Regina; Viana, Isabelle Freire Tabosa; Lins, Roberto Dias; Rigato, Paula Ordonhez; Marques, Ernesto Torres de Azevedo; da Silva Duarte, Alberto Jose; Sato, Maria Notomi

Blockade of caspase cascade overcomes malaria-associated acute respiratory distress syndrome in mice

CELL DEATH & DISEASE

IF9.6

2022-02-10

OAAI

Sercundes, Michelle K.; Ortolan, Luana S.; Julio, Viviane da Silva; Bella, Leonardo M.; Quirino, Thatyane de Castro; Debone, Daniela; Carneiro-Ramos, Marcela S.; Christoffolete, Marcelo A.; Martins, Joilson O.; D'Imperio Lima, Maria Regina; Alvarez, Jose M.; Amarante-Mendes, Gustavo P.; Goncalves, Ligia Antunes; Marinho, Claudio R. F.; Epiphanio, Sabrina

Absence of Bim sensitizes mice to experimental Trypanosoma cruzi infection (vol 12, 817, 2021)

CELL DEATH & DISEASE

IF9.6

2021-08-30

OAAI

Hernandez-Torres, Marcela; do Nascimento, Silva Rogerio; Reboucas, Monica Cardozo; Cassado, Alexandra; Matteucci, Kely Catarine; D'Imperio-Lima, Maria Regina; Vasconcelos, Jose Ronnie C.; Bortoluci, Karina R.; Alvarez, Jose Maria; Amarante-Mendes, Gustavo P.

Absence of Bim sensitizes mice to experimental Trypanosoma cruzi infection

CELL DEATH & DISEASE

IF9.6

2021-07-10

OAAI

Hernandez-Torres, Marcela; do Nascimento, Rogerio Silva; Reboucas, Monica Cardozo; Cassado, Alexandra; Matteucci, Kely Catarine; D'Imperio-Lima, Maria Regina; Vasconcelos, Jose Ronnie C.; Bortoluci, Karina R.; Alvarez, Jose Maria; Amarante-Mendes, Gustavo P.

Harmful Effects of Granulocytic Myeloid-Derived Suppressor Cells on Tuberculosis Caused by Hypervirulent Mycobacteria

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2020-11-18

OAAI

Barbosa Bomfim, Caio Cesar; Amaral, Eduardo Pinheiro; Santiago-Carvalho, Igor; Santos, Gislane Almeida; Salles, Erika Machado; Hastreiter, Araceli Aparecida; do Nascimento, Rogerio Silva; Almeida, Fabricio M.; Bia Ventura Simao, Thatiana Lopes; Rezende, Andreza Linhares; Hirata, Mario Hiroyuki; Fock, Ricardo Ambrosio; Alvarez, Jose Maria; Lasunskaia, Elena B.; D'Imperio Lima, Maria Regina

Combining Host Genetics and Functional Analysis to Depict Inflammasome Contribution in Tuberculosis Susceptibility and Outcome in Endemic Areas

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-10-21

OAAI

De Lima, Dhemerson Souza; Bomfim, Caio C. B.; Leal, Vinicius N. C.; Reis, Edione C.; Soares, Jaine L. S.; Fernandes, Fernanda P.; Amaral, Eduardo P.; Loures, Flavio, V; Ogusku, Mauricio M.; D'Imperio Lima, Maria R.; Sadahiro, Aya; Pontillo, Alessandra

IL-1α, promotes liver inflammation and necrosis during blood-stage Plasmodium chabaudi malaria

SCIENTIFIC REPORTS

IF3.9

2019-05-20

OAAI

de Menezes, Maria Nogueira; Salles, Erika Machado; Vieira, Flavia; Amaral, Eduardo Pinheiro; Zuzarte-Luis, Vanessa; Cassado, Alexandra; Epiphanio, Sabrina; Alvarez, Jose Maria; Alves-Filho, Jose Carlos; Mota, Maria Manuel; D'Imperio-Lima, Maria Regina

Inhibiting Adenosine Receptor Signaling Promotes Accumulation of Effector CD4+ T Cells in the Lung Parenchyma During Severe Tuberculosis

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2018-10-11

OAAI

Amaral, Eduardo P.; de Salles, Erika Machado; Barbosa Bomfim, Caio Cesar; Salgado, Rafael Moyses; Almeida, Fabricio M.; de Souza, Paula Carolina; Alvarez, Jose Maria; Hirata, Mario H.; Lasunskaia, Elena B.; D'Imperio-Lima, Maria Regina

MyD88 activation in cardiomyocytes contributes to the heart immune response to acute Trypanosoma cruzi infection with no effect on local parasite control

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2018-08-01

OAAI

Santana, Danni Yohani; Salgado, Rafael Moyses; Fevereiro, Marina; do Nascimento, Rogerio Silva; Fonseca, Raissa; Saraiva Camara, Niels Olsen; Epiphanio, Sabrina; Farias Marinho, Claudio Romero; Barreto-Chaves, Maria Luiza; D' Imperio-Lima, Maria Regina; Alvarez, Jose M.

Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by Mycobacterium tuberculosis in Infected Macrophages

FRONTIERS IN IMMUNOLOGY

IF5.9

2018-06-21

OAAI

Amaral, Eduardo P.; Riteau, Nicolas; Moayeri, Mahtab; Maier, Nolan; Mayer-Barber, Katrin D.; Pereira, Rosana M.; Lage, Silvia L.; Kubler, Andre; Bishai, William R.; D'Imperio-Lima, Maria R.; Sher, Alan; Andrade, Bruno B.

Programmed Cell Death Protein 1-PDL1 Interaction Prevents Heart Damage in Chronic Trypanosoma cruzi Infection

FRONTIERS IN IMMUNOLOGY

IF5.9

2018-05-07

OAAI

Fonseca, Raissa; Salgado, Rafael Moyses; da Silva, Henrique Borges; do Nascimento, Rogerio Silva; D'Imperio-Lima, Maria Regina; Alvarez, Jose Maria

TLR4-Mediated Placental Pathology and Pregnancy Outcome in Experimental Malaria (vol 7, 2017)

SCIENTIFIC REPORTS

IF3.9

2018-03-06

OAAI

Barboza, Renato; Lima, Flavia Afonso; Reis, Aramys Silva; Murillo, Oscar Javier; Machado Peixoto, Erika Paula; Bandeira, Carla Leticia; Fotoran, Wesley Luzetti; Sardinha, Luis Roberto; Wunderlich, Gerhard; Bevilacqua, Estela; D'Imperio Lima, Maria Regina; Alvarez, Jose Maria; Maranhao Costa, Fabio Trindade; Goncalves, Ligia Antunes; Epiphanio, Sabrina; Farias Marinho, Claudio Romero

研究方向