管政兵 (Zheng-Bing Guan)

Jiangnan University江苏省第十一批科技镇长团成员

H指数:1

被引数:6

个人简介

"1981年出生，2009.6~2013.10 校聘副教授，2013.11~至今副教授，2018.8~2019.8任江苏省第十一批科技镇长团成员（挂职扬州仪征市）。从事发酵食品、药食同源、食品酶、益生菌、产香微生物、食品加工副产物发酵资源化、生物保鲜剂等方面研究工作，以第一/通讯作者发表SCI论文30多篇，授权国家发明专利15项，主持各类科研项目20余项，取得科技成果奖励3项，曾获江南大学优秀班主任、优秀毕业论文指导教师、教学成果奖等。\n学习工作经历点击展开\n.\n主要成果点击展开\n【代表性论著】 [1] Zhang ZH, Liao YX, Deng XT, Guan ZB*. Semi-rational engineering of glucosamine-6-phosphate deaminase for catalytic synthesis of glucosamine from D-fructose. Enzyme and Microbial Technology, 2025, 183:110552. [2] Guan ZB*, Deng XT, Zhang ZH, Xu GC, Cheng WL, Liao XR, Cai YJ. Engineering Glucosamine-6-Phosphate Synthase to Achieve Efficient One-Step Biosynthesis of Glucosamine. ACS Chemical Biology, 2024, 19:1237-1242. [3] Yang CX, Zhang D, Ma H, Guo XM, Yan N, Deng XT, Liao XR, Guan ZB*. Screening of Strain from Reconstituted Sheet Tobacco Making High‑Yield Enzyme and Aroma. Proc. Natl. Acad. Sci., India, Sect. B Biol. Sci. 2024, 94:641-651. [4] Yan N, Ma H, Yang CX, Liao XR, Guan ZB*. Improving the decolorization activity of Bacillus pumilus W3 CotA-laccase to Congo Red by rational modification. Enzyme and Microbial Technology, 2022, 155:109977. [5] Ma H, Xu KZ, Wang YJ, Yan N, Liao XR, Guan ZB*. Enhancing the decolorization activity of Bacillus pumilus W3 CotA-laccase to Reactive Black 5 by site-saturation mutagenesis. Applied Microbiology and Biotechnology, 2020, 104:9193-9204. [6] Wang YJ, Xu KZ, Ma H, Liao XR, Guo G, Tian F, Guan ZB*. Recombinant horseradish peroxidase C1A immobilized on hydrogel matrix for dye decolorization and its mechanism on acid blue 129 degradation. Applied Biochemistry and Biotechnology, 2020, 192:861-880. [7] Xu KZ, Wang HR, Wang YJ, Xia J, Ma H, Cai YJ, Liao XR, Guan ZB*. Enhancement in catalytic activity of CotA-laccase from Bacillus pumilus W3 via site-directed mutagenesis. Journal of Bioscience and Bioengineering, 2020, 129:405-411. [8] Xu KZ, Ma H, Wang YJ, Cai YJ, Liao XR, Guan ZB*. Extracellular expression of mutant CotA-laccase SF in Escherichia coli and its degradation of malachite green. Ecotoxicology and Environmental Safety, 2020, 193:110335. [9] Xia J, Wang Q, Luo Q, Chen Y, Liao XR, Guan ZB*. Secretory expression and optimization of Bacillus pumilus CotA-laccase mutant GWLF in Pichia pastoris and its mechanism on evans blue degradation. Process Biochemistry, 2019, 78:33-41. [10] Guan ZB*, Luo Q, Wang HR, Chen Y, Liao XR. Bacterial laccases: promising biological green tools for industrial applications. Cellular and Molecular Life Sciences, 2018, 75:3569-3592. [11] Luo Q, Chen Y, Xia J, Wang KQ, Cai YJ, Liao XR, Guan ZB*. Functional expression enhancement of Bacillus pumilus W3 CotA-laccase mutant WLF through site-directed mutagenesis. Enzyme and Microbial Technology, 2018, 109:11-19. [12] Chen Y, Luo Q, Zhou W, Xie Z, Cai YJ, Liao XR, Guan ZB*. Improving the catalytic efficiency of Bacillus pumilus W3 CotA-laccase by site-directed mutagenesis. Applied Microbiology and Biotechnology, 2017, 101:1935-1944. [13] Zhou W, Guan ZB*, Chen Y, Zhang F, Cai YJ, Xu CW, Chen XS, Liao XR. Production of spore laccase from Bacillus pumilus W3 and its application in dye decolorization after immobilization. Water Science and Technology, 2017, 76:147-154. [14] Guan ZB*, Wang KQ, Shui Y, Liao XR. Establishment of a markerless multiple-gene deletion method based on Cre/loxP mutant system for Bacillus pumilus. Journal of Basic Microbiology, 2017, 57:1065-1068. [15] Guan ZB, Yi HX, Zhao H, Shui Y, Cai YJ, Liao XR. Cell division cycle 2 participates in eyestalk ablation-induced ovarian maturation of Procambarus clarkii. Aquaculture, 2017, 468:115-119. [16] Guan ZB, Yin J, Chen K, Shui Y, Cai YJ, Liao XR. The hepatopancreas and ovary are the sites of vitellogenin synthesis in female red swamp crayfish (Procambarus clarkii). Journal of Crustacean Biology, 2016, 36:637-641. [17] Guan ZB, Cai YJ, Zhang YZ, Zhao H, Liao XR. Complete genome sequence of Bacillus pumilus W3: A strain exhibiting high laccase activity. Journal of Biotechnology, 2015, 207:8-9. [18] Guan ZB, Shui Y, Song CM, Zhang N, Cai YJ, Liao XR. Efficient secretory production of CotA-laccase and its application in the decolorization and detoxification of industrial textile wastewater. Environmental Science and Pollution Research, 2015, 22:9515-9523. [19] Guan ZB, Song CM, Zhang N, Zhou W, Xu CW, Zhou LX, Zhao H, Cai YJ, Liao XR. Overexpression, characterization, and dye-decolorizing ability of a thermostable, pH-stable, and organic solvent-tolerant laccase from Bacillus pumilus W3. Journal of Molecular Catalysis B, Enzymatic, 2014, 101:1-6. [20] Guan ZB, Zhang N, Song CM, Zhou W, Zhou LX, Zhao H, Xu CW, Cai YJ, Liao XR. Molecular Cloning, Characterization, and Dye-Decolorizing Ability of a Temperature- and pH-Stable Laccase from Bacillus subtilis X1. Applied Biochemistry and Biotechnology, 2014, 172:1147-1157. [21] Guan ZB, Shui Y, Liao XR, Xu ZH, Zhou X. Primary structure of a novel gonadotropin-releasing hormone (GnRH) in the ovary of red swamp crayfish Procambarus clarkii. Aquaculture, 2014, 418-419:67-71. [22] Guan ZB, Shui Y, Zhou X, Xu ZH, Zhao CY, Song CM, Liao XR. Participation of calmodulin (CaM) in ovarian maturation induced by eyestalk ablation in red swamp crayfish Procambarus clarkii. Aquaculture Research, 2013, 44:1625-1631. [23] Guan ZB, Zhang ZZ, Cao Y, Chen LL, Xie GF, Lu J. Analysis and comparison of bacterial communities in two types of “wheat Qu”, the starter culture of Shaoxing rice wine, using nested PCR-DGGE. Journal of Institute Brewing, 2012, 118:127-132. [24] Guan ZB, Shui Y, Lu J. Molecular identification of the gene encoding porcine tristetraprolin (TTP). Molecular and Cellular Biochemistry, 2010, 345:145-151. [25] Guan ZB, Cai GL, Sun JY, Lu J. Identification and expression analysis of bovine ANGPTL gene family. Current Zoology, 2010, 56:444-452. [26] Guan ZB, Shui Y, Zhang JX, Zhang SQ. Molecular cloning, genomic organization and expression analysis of the gene encoding bovine (Bos taurus) B-cell activating factor belonging to "