孙付保 (Fubao Sun)

Jiangnan University教授，博士生导师

H指数:35

被引数:4,476

个人简介

"江南大学至善岗位教授，江苏省“333高层次人才”和 “六大人才高峰” 等政府荣誉，以及“桑麻”学者、“杜邦”学者、“蔚蓝生物”学者等社会荣誉获得者。作为项目首席，承担国家重点研发计划国合专项和国家自然科学基金（联合）重点；作为生物资源与生物炼制研究团队负责人，带领团队长期从事生物炼制、发酵工程、酶工程、代谢工程和合成生物学等方面的科研教学工作；团队成员包括：孙驰贺副研究员、Meysam Madadi副研究员和胡芸实验师。团队近5年承担国家重点研发计划重点专项课题、国家重点研发计划国际合作专项、国家自然科学基金重点（联合）/国际合作/面上/青年等省部级以上科研项目20余项，以及企业委托项目10余项；授权国家发明专利20余件（含美国专利2件）、发表高水平论文120余篇；获得广西壮族自治区技术发明一等奖等省部级奖励6项；团队负责人为国际杂志J Chem Technol Biotechnol编委（2013-）、Advances in Environmental Technology编委（2023-）、Current Nutrition& Food Science 编委(2025-)、中国生物工程学会会员和生物质能专委会委员。团队研究方向 1）酶工程、代谢工程和合成生物学大健康功能性配料的绿色生物制造，具体包括：饲用抗生素、萜烯类化合物和高附加值氨基酸等生产菌种选育、微生物酶改造、代谢合成途径分析、发酵过程优化与控制等。 2）生物炼制围绕国家“双碳”战略，开展生物基化学品/能源/材料先进生物制造的理论创新和技术升级，具体包括：农林生物质原料组成结构的绿色高效拆解；微生物酶挖掘和迭代进化改造；多碳源抗逆性共发酵工程菌的合成生物学改造；酶解糖化 / 发酵过程的AI辅助优化与智能性控制。\n学习工作经历点击展开\n2001.9-2004.4：大连工业大学，发酵工程，硕士 2004.9-2008.9：中国科学院过程工程研究所，生物化工，博士 2009.1-2012.9：江南大学生物工程学院，讲师 2012.5-2019.5：江南大学生物工程学院，副教授，硕士生导师 2019.6-现在：江南大学生物工程学院教授，博士生导师其中： 2012.5-2013.5：加拿大不列颠哥伦比亚大学(UBC)，博士后 2016.7-2016.9：明尼苏达大学(UMN)，访问学者\n主要成果点击展开\n一、论文（论著）发表情况团队近5年以通讯或一作在Nature foods, Adv. Sci., Biotechnol. Adv., Chem. Eng. J., Green Chem.等发表SCI研究论文100余篇，代表性文章如下： 2026年 1）酶工程、代谢工程部分 [1]Haobo Xing, Qingming Hou, Zhenhua Wang, Shanfei Zhang*, Shangxia Song, Lulu Du, Chenghua Gao, Yunfei Li, Fubao Sun*. Overexpression of new genes in Streptomyces cinnamonensis for efficient monensin biosynthesis with a multi-module collaborative strategy. Biochemical Engineering Journal 230 (2026) 110118 [2] Xiaotong Kang, Hang Yuan, Weimeng Li, Yun Hu *, Fubao Sun *. Enhanced activity and stability of thermostable endoglucanase Dictyoglomus turgidum DtCelA with multiple strategies. Enzyme and Microbial Technology 195 (2026) 110809 2）生物炼制部分 [3] Salauddin Al Azad, Ehsan Kargaran, Maryam Saleknezhad, Yuanchao Cheng, Conghui Quan, Junyao Chen, Chihe Sun, Meysam Madadi *, Fubao Sun *. Choline chloride enables low-severity NaOH/Triton-X 100pretreatment and lignin upgradingto enriched aromatic bio-oil andporous biochar. Chemical Engineering Journal, DOI: 10.1016/j.cej.2026.176853 (2026) [4] Meysam Madadi *, Zicheng Liu, Salauddin Al Azad, Ehsan Kargaran, Chihe Sun, Vijai Kumar Gupta & Fubao Sun *. Amino-acid interface engineering of lignin for functional carbon production and reinforced 3D‑printed PLA composites. Advanced Composites and Hybrid Materials‌, DOI: 10.1007/s42114-026-01796-6 (2026) 2025年 1）微生物酶工程、代谢工程部分 [1] Zhang, Shanfei, Qingming Hou, Zhenhua Wang, Xianyuan Zhang, Dandan Tian, Yan Zhang, Dandan Wang, Ning Chen, Fubao Sun*. Enhanced monensin production via co-fermentation of lignocellulosic hydrolysate using mutated streptomyces cinnamonensis. Industrial Crops and Products, 2025, 230: 121119. [2] Weimeng Li, Hang Yuan, Yun Hu*, Shaohua Dou, Ezhen Zhang*, QunWu, Fubao Sun*. Construction of new thermostable MtLPMO9V in synergism with cellulases for efficient lignocellulosic hydrolysis. Bioresource Technology, (2025): 132594. [3] Hang Yuan, Samaila Boyi Ajeje, Yunzhe Wen, Chonlong Chio, Yun Hu, Shaohua Dou, Wensheng Qin, Ezhen Zhang, Qun Wu, Fubao Sun*. Enhancement of the catalytic activity of thermostable Endo-1, 4-β-glucanase B (TnCelB) from Thermotoga neapolitana by error-prone PCR. International Journal of Biological Macromolecules, 2025, 308: 142310. [4] Qiangqiang Liu, Meysam Madadi, Salauddin Al Azad, Xingmei Lu, Hong Yan, Qing Zhou, Chihe Sun*, Fubao Sun*. Unveiling the mechanisms of mixed surfactant synergy in passivating lignin-cellulase interactions during lignocellulosic saccharification. Journal of Colloid and Interface Science, 2025, 681: 404-415. [5] Qiangqiang Liu, Chihe Sun, Meysam Madadi*, Ezhen Zhang, Ao Xia, Abdolreza Samimi, Fubao Sun*. Elucidation of mixed surfactants reducing mass transfer resistance during high-solids enzymatic hydrolysis from lignocellulosic biomass. Chemical Engineering Journal, 2025, 507: 160332. [6] Shanfei Zhang, Zhenhua Wang, Dandan Tian, Yan Zhang, Chihe Sun, Qingming Hou, Jingle Liang *, Qun Wu, Fubao Sun *. Effect of exogenous addition of fatty acids on the production of monensin from Streptomyces cinnamonensis fermentation. Process Biochemistry, 2025, 156: 350-358 [7] Zhang, Shanfei, Qingming Hou, Zhenhua Wang, Xianyuan Zhang, Dandan Tian, Yan Zhang, Dandan Wang, Ning Chen, Fubao Sun*. Enhanced monensin production via co-fermentation of lignocellulosic hydrolysate using mutated streptomyces cinnamonensis. Industrial Crops and Products, 2025, 230: 121119. [8] Shanfei Zhang, Zhenhua Wang, Qingming Hou, Xianyuan Zhang, Dandan Tian, Yan Zhang, Qun Wu, Fubao Sun*. Identification of specific genes related to efficient Monensin biosynthesis in Streptomyces cinnamonensis with genomic analysis. Systems Microbiology and Biomanufacturing, 2025: 1-11. [9] Shanfei Zhang, Qingming Hou, Zhenhua Wang, Dandan Tian, Xianyuan Zhang, Yan Zhang, Qun Wu, Fubao Sun*. Fatty acid addition strategy redirected the metabolic flux towards an ultra-high monensin productivity of Streptomyces cinnamonensis. Synthetic and Systems Biotechnology, 2025, 10(2): 532-542. 2）生物炼制部分 [10] Meysam Madadi*, Hamid Amiri, Junting Pan, Guojie Song, Dan Liu, Vijai Kumar Gupta*, Mortaza Aghbashlo, Meisam Tabatabaei. \"Food loss and waste valorization offers a sustainable source of biopolymers in bioinks for 3D printing.\" Nature Food, 2025: 1-8. [11] Guojie Song, Peng Teng, Meysam Madadi*, Hadiyanto Hadiyanto, Chihe Sun*, Jinguang Hu, Fubao Sun*. \"Fabrication of lignin-containing cellulose nanofibrils with unique properties via a simple PEG-assisted strategy.\" Carbohydrate Polymers, 2025, 370, 124363. [12] Guojie Song, Salauddin Al Azad, Wenhao Hu, Meysam Madadi, Ashfaque Rahman, Chihe Sun, Fubao Sun. \"Comparison study and mechanisms insight of AlCl3-catalyzed different organosolv pretreatment of lignocellulose: Enhancing enzymatic hydrolysis, lignin fractionation, and furfural production.\" Bioresource Technology, 2026, 439, 133308. [13] Meysam Madadi, Mahdy Elsayed, Guojie Song, Razieh Shafiei-Alavijeh, Joeri F. Denayer, Ehsan Kargaran, Salauddin Al Azad, Keikhosr"