未登录 Short-term disruption of TGF-β signaling in adult mice renders the aorta vulnerable to hypertension-induced dissection 短期阻断成年小鼠中的TGF-β信号通路会使主动脉对高血压诱导的夹层更加易感。 Jiang, Bo; Ren, Pengwei; He, Changshun; Wang, Mo; Murtada, Sae-Il; Ruiz-Rodriguez, Maria Jesus; Chen, Yu; Ramachandra, Abhay B.; Li, Guangxin; Qin, Lingfeng; Assi, Roland; Schwartz, Martin A.; Humphrey, Jay D.; Tellides, George 分享 收藏
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Lonafarnib improves cardiovascular function and survival in a mouse model of Hutchinson-Gilford progeria syndrome Murtada, Sae-Il; Mikush, Nicole; Wang, Mo; Ren, Pengwei; Kawamura, Yuki; Ramachandra, Abhay B.; Li, David S.; Braddock, Demetrios T.; Tellides, George; Gordon, Leslie B.; Humphrey, Jay D. 分享 收藏
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Fibronectin-Integrin α5 Signaling in Vascular Complications of Type 1 Diabetes Chen, Minghao; Hu, Rui; Cavinato, Cristina; Zhuang, Zhenwu W.; Zhang, Jiasheng; Yun, Sanguk; Fernandez Tussy, Pablo; Singh, Abhishek; Murtada, Sae-Il; Tanaka, Keiichiro; Liu, Min; Fernandez-Hernando, Carlos; Humphrey, Jay D.; Schwartz, Martin A. 分享 收藏
Response of enthesopathy in ENPP1 deficiency to enzyme replacement therapy in murine models and enthesopathy comorbidities and quality of life in ENPP1-deficient adults Ansh, Anenya J.; Nester, Catherine; O'Brien, Christine; Stabach, Paul R.; Murtada, Sae-Il; Lester, Ethan R.; Khursigara, Gus; Molloy, Liz; Carpenter, Thomas O.; Ferreira, Carlos R.; Braddock, Demetrios T. 分享 收藏
mTOR inhibition prevents angiotensin II-induced aortic rupture and pseudoaneurysm but promotes dissection in mice mTOR抑制可预防血管紧张素II诱导的主动脉破裂和假性动脉瘤,但可促进小鼠夹层 He, Changshun; Jiang, Bo; Wang, Mo; Ren, Pengwei; Murtada, Sae-Il; Caulk, Alexander W.; Li, Guangxin; Qin, Lingfeng; Assi, Roland; Lovoulos, Constantinos J.; Schwartz, Martin A.; Humphrey, Jay D.; Tellides, George 分享 收藏
Musculoskeletal Comorbidities and Quality of Life in ENPP1-Deficient Adults and the Response of Enthesopathy to Enzyme Replacement Therapy in Murine Models Ferreira, Carlos R.; Ansh, Anenya Jai; Nester, Catherine; O'Brien, Christine; Stabach, Paul R.; Murtada, Sae-Il; Lester, Ethan R.; Khursigara, Gus; Molloy, Liz; Carpenter, Thomas O.; Braddock, Demetrios T. 分享 收藏
Inhibition of HIPK2 Alleviates Thoracic Aortic Disease in Mice With Progressively Severe Marfan Syndrome Caescu, Cristina, I; Hansen, Jens; Crockett, Brittany; Xiao, Wenzhen; Arnaud, Pauline; Spronck, Bart; Weinberg, Alan; Hashimoto, Takeshi; Murtada, Sae-Il; Borkar, Roshan; Gallo, James M.; Jondeau, Guillaume; Boileau, Catherine; Humphrey, Jay D.; He, John Cijiang; Iyengar, Ravi; Ramirez, Francesco 分享 收藏
Excessive adventitial stress drives inflammation-mediated fibrosis in hypertensive aortic remodelling in mice Spronck, Bart; Latorre, Marcos; Wang, Mo; Mehta, Sameet; Caulk, Alexander W.; Ren, Pengwei; Ramachandra, Abhay B.; Murtada, Sae-Il; Rojas, Alexia; He, Chang-Shun; Jiang, Bo; Bersi, Matthew R.; Tellides, George; Humphrey, Jay D. 分享 收藏
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Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth Nandadasa, Sumeda; Szafron, Jason M.; Pathak, Vai; Murtada, Sae-Il; Kraft, Caroline M.; O'Donnell, Anna; Norvik, Christian; Hughes, Clare; Caterson, Bruce; Domowicz, Miriam S.; Schwartz, Nancy B.; Tran-Lundmark, Karin; Veigl, Martina; Sedwick, David; Philipson, Elliot H.; Humphrey, Jay D.; Apte, Suneel S. 分享 收藏
Paradoxical aortic stiffening and subsequent cardiac dysfunction in Hutchinson-Gilford progeria syndrome Murtada, S-, I; Kawamura, Y.; Caulk, A. W.; Ahmadzadeh, H.; Mikush, N.; Zimmerman, K.; Kavanagh, D.; Weiss, D.; Latorre, M.; Zhuang, Z. W.; Shadel, G. S.; Braddock, D. T.; Humphrey, J. D. 分享 收藏
Smooth Muscle Cell Reprogramming in Aortic Aneurysms Chen, Pei-Yu; Qin, Lingfeng; Li, Guangxin; Malagon-Lopez, Jose; Wang, Zheng; Bergaya, Sonia; Gujja, Sharvari; Caulk, Alexander W.; Murtada, Sae-Il; Zhang, Xinbo; Zhuang, Zhen W.; Rao, Deepak A.; Wang, Guilin; Tobiasova, Zuzana; Jiang, Bo; Montgomery, Ruth R.; Sun, Lele; Sun, Hongye; Fisher, Edward A.; Gulcher, Jeffrey R.; Fernandez-Hernando, Carlos; Humphrey, Jay D.; Tellides, George; Chittenden, Thomas W.; Simons, Michael 分享 收藏
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Systems pharmacology-based integration of human and mouse data for drug repurposing to treat thoracic aneurysms Hansen, Jens; Galatioto, Josephine; Caescu, Cristina, I; Arnaud, Pauline; Calizo, Rhodora C.; Spronck, Bart; Murtada, Sae-Il; Borkar, Roshan; Weinberg, Alan; Azeloglu, Evren U.; Bintanel-Morcillo, Maria; Gallo, James M.; Humphrey, Jay D.; Jondeau, Guillaume; Boileau, Catherine; Ramirez, Francesco; Iyengar, Ravi 分享 收藏
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