王立宾 (Libin Wang)

lanzhou university of technology副研究员，助理教授

H指数:25

被引数:1,626

个人简介

"王立宾，细胞生物学系课题组组长，女性生育力促进全国重点实验室、干细胞再生医学北京市重点实验室PI，博士生导师，入选国家高层次人才计划。于中国科学院动物研究所进行博士和博士后训练，师从干细胞发育生物学家周琪院士。2023年入职基础医学院，长期从事创新型干细胞驱动的复杂遗传病机制解析。相关研究成果以第一作者（含共同）发表于 Science (2022), Cell Stem Cell (2025, 2020, 2018)等期刊，其中首次实现哺乳动物完整染色体精确融合的研究工作( Science , 2022)入选中国生命科学十大进展；在哺乳动物中首次实现同性生殖的研究工作( Cell Stem Cell , 2018)入选世界七项顶级技术突破。承担国自然面上项目、国家重点研发计划项目等。现任中国医药生物技术协会基因工程与细胞工程制药专业委员， Cell Proliferation 及 Life Medicine 等期刊编委。\n学习及工作经历\n2006.09-2011.06：吉林大学白求恩医学部生物工程专业，获医学和理学双学士学位\n2011.09-2018.06：中国科学院动物研究所，获再生医学博士学位\n2018.06-2023.05：中国科学院动物研究所，博士后\n2023.06-至今：北京大学基础医学院细胞生物学系副研究员，助理教授\n代表性工作\n1. Wang Li-Bin, Li Zhi-Kun, Wang Le-Yun, Xu Kai, Ji Tian-Tian, Mao Yi-Huan, Ma Si-Nan, Liu Tao, Tu Cheng-Fang, Zhao Qian, Fan Xu-Ning, Liu Chao, Wang Li-Ying, Shu You-Jia, Yang Ning, Zhou Qi*, Li Wei* ; A sustainable mouse karyotype created by programmed chromosome fusion; Science; 2022, 377 :967-975.\n2. Zhi-Kun Li, Li-Bin Wang, Le-Yun Wang , Xue-Han Sun, Ze-Hui Ren, Si-Nan Ma, Yu-Long Zhao, Chao Liu, Gui-Hai Feng, Tao Liu, Tian-Shi Pan, Qing-Tong Shan, Kai Xu, Guan-Zheng Luo*, Qi Zhou*, Wei Li*. Adult bi-paternal offspring generated through direct modification of imprinted genes in mammals; Cell Stem Cell;2025, 32; 361-374.\n3. Wang Le-Yun, Li Zhi-Kun, Wang Li-Bin, Liu Chao, Sun Xue-Han, Feng Gui-Hai, Wang Jia-Qiang, Li Yu-Fei, Qiao Lian-Yong, Nie Hu, Jiang Li-Yuan, Sun Hao, Xie Ya-Li, Ma Si-Nan, Wan Hai-Feng, Lu Fa-Long*, Li Wei*, Zhou Qi*; Overcoming Intrinsic H3K27me3 Imprinting Barriers Improves Postimplantation Development after Somatic Cell Nuclear Transfer; Cell Stem Cell; 2020, 27 :315-325 e315.\n4. Li Zhi-Kun, Wang Le-Yun, Wang Li-Bin, Feng Gui-Hai, Yuan Xue-Wei, Liu Chao, Xu Kai, Li Yu-Huan, Wan Hai-Feng, Zhang Ying, Li Yu-Fei, Li Xin, Li Wei*, Zhou Qi*, Hu Bao-Yang*; Generation of Bimaternal and Bipaternal Mice from Hypomethylated Haploid ESCs with Imprinting Region Deletions; Cell Stem Cell; 2018, 23 :665-676 e664.\n5. Libin Wang, Jiani Cao, Yukai Wang, Tianshu Lan, Lei Liu, Weixu Wang, Ning Jin, Jiaqi Gong, Chao Zhang, Fei Teng, Guoliang Yan, Chun Li, Jiali Li, Haifeng Wan, Baoyang Hu, Wei Li, Xiaoyang Zhao, Zhongquan Qi*, Tongbiao Zhao*, Qi Zhou*. Immunogenicity and functional evaluation of iPSC-derived organs for transplantation. Cell Discovery; 2015, 1, 15015.\n王立宾副研究员1954Peking University School of Basic Medical Sciences王立宾副研究员1细胞生物学系"