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Phenotypic rescue via mTOR inhibition in neuron-specific Pten knockout mice reveals AKT and mTORC1-site specific changes 通过抑制mTOR实现的表型拯救在神经元特异性Pten基因敲除小鼠中揭示了AKT和mTORC1位点特异性变化 D'Amore, Angelica; Sundberg, Maria; Lin, Rui; Lubbers, Ella T.; Winden, Kellen D.; Yu, Lucy; Gawlinska, Kinga; Gawlinski, Dawid; Lopez, Sam G.; Choe, Yongho; Wightman, Emma V.; Liang, Yini; Modi, Meera; Yuskaitis, Christopher J.; Lee, Henry Hing Cheong; Rotenberg, Alexander; Sahin, Mustafa 分享 收藏
Neurodevelopmental copy-number variants: A roadmap to improving outcomes by uniting patient advocates, researchers, and clinicians for collective impact Buttermore, Elizabeth; Chamberlain, Stormy; Cody, Jannine; Costain, Gregory; Dang, Louis; DeWoody, Andrew; DeWoody, Yssa; Dies, Kira; Eichler, Evan; Girirajan, Santhosh; Gramm, Marie; Halladay, Alycia; Lal, Dennis; Lalli, Matthew; Levy, Tess; Logsdon, Glennis; Lowenstein, Daniel; Mefford, Heather; Mulle, Jennifer; Muotri, Alysson; Murphy, Melissa; Palma, Eduardo Perez; Pinter, Stefan; Pollak, Rebecca; Purcell, Ryan; Samaco, Rodney; Shah, Bina; Singh, Karun; So, Joyce; Sundberg, Maria; Veeraragavan, Surabi; Vogel-Farley, Vanessa; Wynshaw-Boris, Anthony 分享 收藏
A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo Hernandez, J. O. R.; Wang, X.; Vazquez-Segoviano, M.; Lopez-Marfil, M.; Sobral-Reyes, M. F.; Moran-Horowich, A.; Sundberg, M.; Lopez-Cantu, D. O.; Probst, C. K.; Ruiz-Esparza, G. U.; Giannikou, K.; Abdi, R.; Henske, E. P.; Kwiatkowski, D. J.; Sahin, M.; Lemos, D. R. 分享 收藏
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16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro Sundberg, Maria; Pinson, Hannah; Smith, Richard S.; Winden, Kellen D.; Venugopal, Pooja; Tai, Derek J. C.; Gusella, James F.; Talkowski, Michael E.; Walsh, Christopher A.; Tegmark, Max; Sahin, Mustafa 分享 收藏
Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin Sundberg, Maria; Tochitsky, Ivan; Buchholz, David E.; Winden, Kellen; Kujala, Ville; Kapur, Kush; Cataltepe, Deniz; Turner, Daria; Han, Min-Joon; Woolf, Clifford J.; Hatten, Mary E.; Sahin, Mustafa 分享 收藏
Successful Function of Autologous iPSC-Derived Dopamine Neurons following Transplantation in a Non-Human Primate Model of Parkinson's Disease Hallett, Penelope J.; Deleidi, Michela; Astradsson, Arnar; Smith, Gaynor A.; Cooper, Oliver; Osborn, Teresia M.; Sundberg, Maria; Moore, Michele A.; Perez-Torres, Eduardo; Brownell, Anna-Liisa; Schumacher, James M.; Spealman, Roger D.; Isacson, Ole 分享 收藏
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Improved Cell Therapy Protocols for Parkinson's Disease Based on Differentiation Efficiency and Safety of hESC-, hiPSC-, and Non-Human Primate iPSC-Derived Dopaminergic Neurons 基于hESC-，hiPSC-和非人灵长类动物iPSC衍生的多巴胺能神经元的分化效率和安全性，改善了帕金森氏病的细胞治疗方案 Sundberg, Maria; Bogetofte, Helle; Lawson, Tristan; Jansson, Johan; Smith, Gaynor; Astradsson, Arnar; Moore, Michele; Osborn, Teresia; Cooper, Oliver; Spealman, Roger; Hallett, Penelope; Isacson, Ole 分享 收藏
Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease Cooper, Oliver; Seo, Hyemyung; Andrabi, Shaida; Guardia-Laguarta, Cristina; Graziotto, John; Sundberg, Maria; McLean, Jesse R.; Carrillo-Reid, Luis; Xie, Zhong; Osborn, Teresia; Hargus, Gunnar; Deleidi, Michela; Lawson, Tristan; Bogetofte, Helle; Perez-Torres, Eduardo; Clark, Lorraine; Moskowitz, Carol; Mazzulli, Joseph; Chen, Li; Volpicelli-Daley, Laura; Romero, Norma; Jiang, Houbo; Uitti, Ryan J.; Huang, Zhigao; Opala, Grzegorz; Scarffe, Leslie A.; Dawson, Valina L.; Klein, Christine; Feng, Jian; Ross, Owen A.; Trojanowski, John Q.; Lee, Virginia M. -Y.; Marder, Karen; Surmeier, D. James; Wszolek, Zbigniew K.; Przedborski, Serge; Krainc, Dimitri; Dawson, Ted M.; Isacson, Ole 分享 收藏
Markers of Pluripotency and Differentiation in Human Neural Precursor Cells Derived From Embryonic Stem Cells and CNS Tissue Sundberg, M.; Andersson, P. -H.; Akesson, E.; Odeberg, J.; Holmberg, L.; Inzunza, J.; Falci, S.; Ohman, J.; Suuronen, R.; Skottman, H.; Lehtimaki, K.; Hovatta, O.; Narkilahti, S.; Sundstrom, E. 分享 收藏
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