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Synthetic lethality in the context of STAG2-mutant Ewing sarcoma Mous, Lieke; Hofer, Michelle; Zabele, Dorita; Bechtold, Ingrid; Zaidi, Sakina; Fouassier, Camille; Gestraud, Pierre; Bore, Aurelien; Margueron, Raphael; Wachtel, Marco; Schafer, Beat; Delattre, Olivier; Surdez, Didier 分享 收藏
The gray area of RQ-PCR-based measurable residual disease: subdividing the positive, below quantitative range category Kotrova, Michaela; Fronkova, Eva; Svaton, Michael; Drandi, Daniela; Schoen, Felix; Hoogeveen, Patricia; Hancock, Jeremy; Skotnicova, Aneta; Schilhabel, Anke; Eckert, Cornelia; Clappier, Emmanuelle; Cazzaniga, Gianni; Schaefer, Beat W.; van Dongen, Jacques J. M.; Ritgen, Matthias; Pott, Christiane; van der Velden, Vincent H. J.; Trka, Jan; Brueggemann, Monika 分享 收藏
Analysis of measurable residual disease by IG/TR gene rearrangements: quality assurance and updated EuroMRD guidelines van der Velden, Vincent H. J.; Dombrink, Isabel; Alten, Julia; Cazzaniga, Giovanni; Clappier, Emmanuelle; Drandi, Daniela; Eckert, Cornelia; Fronkova, Eva; Hancock, Jeremy; Kotrova, Michaela; Kraemer, Rebekka; Montonen, Mirkka; Pfeifer, Heike; Pott, Christiane; Raff, Thorsten; Trautmann, Heiko; Cave, Helene; Schaefer, Beat W.; van Dongen, Jacques J. M.; Trka, Jan; Brueggemann, Monika; van der Velden, Vincent H. J.; Raff, Thorsten; van Dongen, Jacques J. M. 分享 收藏
ITCC-P4, a preclinical proof-of-concept drug testing platform as a tool for pharmacological screening in pediatric tumor models ITCC-P4，一个临床前概念验证药物测试平台，作为儿科肿瘤模型药理筛选的工具 Indersie, Emilie; Branchereau, Sophie; Fresneau, Brice; Chardot, Christophe; Surdez, Didier; Saint-Charles, Alexandra; da Costa, Maria Eugenia Marques; Carcaboso, Angel M.; Scotlandi, Katia; Moro, Massimo; Kovar, Heinrich; Klusmann, Jan-Henning; Debatin, Klaus-Michael; Bomken, Simon; Chesler, Louis; Jones, Chris; Schafer, Beat; Wachtel, Marco; Gojo, Johannes; Berger, Walter; Guttke, Christina; Hattersley, Maureen; Colland, Frederic; Strougo, Ashley; Gurgen, Dennis; Hoffmann, Jens; Schueler, Julia; Aviles, Pablo M.; Guillen, Maria Jose; Federico, Aniello; Gopisetty, Apurva; Wierzbinska, Justyna Anna; Schlicker, Andreas; Colombetti, Sara; Heidenreich, Olaf; Iradier, Fatima; Huebener, Nicole; Jager, Natalie; Koster, Jan; Kool, Marcel; Schleiermacher, Gudrun; Molenaar, Jan J.; Geoerger, Birgit; Shields, David J.; Caron, Hubert N.; Stancato, Louis F.; Pfister, Stefan M.; Vassal, Gilles; Rief, Eva-Maria; Deas, Olivier 分享 收藏
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Elimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models Elimusertib在临床前患者衍生的儿科实体瘤模型中具有抗肿瘤活性 Pusch, Fabian F.; Garcia, Heathcliff Dorado; Xu, Robin; Guergen, Dennis; Bei, Yi; Brueckner, Lotte; Roeefzaad, Claudia; von Stebut, Jennifer; Bardinet, Victor; Gonzalez, Rocio Chamorro; Eggert, Angelika; Schulte, Johannes H.; Hundsdoerfer, Patrick; Seifert, Georg; Haase, Kerstin; Schaefer, Beat W.; Wachtel, Marco; Kuehl, Anja A.; Ortiz, Michael V.; Wengner, Antje M.; Scheer, Monika; Henssen, Anton G. 分享 收藏
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting Pomella, Silvia; Cassandri, Matteo; D'Archivio, Lucrezia; Porrazzo, Antonella; Cossetti, Cristina; Phelps, Doris; Perrone, Clara; Pezzella, Michele; Cardinale, Antonella; Wachtel, Marco; Aloisi, Sara; Milewski, David; Colletti, Marta; Sreenivas, Prethish; Walters, Zoe S.; Barillari, Giovanni; Di Giannatale, Angela; Milano, Giuseppe Maria; De Stefanis, Cristiano; Alaggio, Rita; Rodriguez-Rodriguez, Sonia; Carlesso, Nadia; Vakoc, Christopher R.; Velardi, Enrico; Schafer, Beat W.; Guccione, Ernesto; Gatz, Susanne A.; Wasti, Ajla; Yohe, Marielle; Ignatius, Myron; Quintarelli, Concetta; Shipley, Janet; Miele, Lucio; Khan, Javed; Houghton, Peter J.; Marampon, Francesco; Gryder, Berkley E.; De Angelis, Biagio; Locatelli, Franco; Rota, Rossella 分享 收藏
PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution Asante, Yaw; Benischke, Katharina; Osman, Issra; Ngo, Quy A.; Wurth, Jakob; Laubscher, Dominik; Kim, Hyunmin; Udhayakumar, Bhavatharini; Khan, Md Imdadul H.; Chin, Diana H.; Porch, Jadon; Chakraborty, Maharshi; Sallari, Richard; Delattre, Olivier; Zaidi, Sakina; Morice, Sarah; Surdez, Didier; Danielli, Sara G.; Schaefer, Beat W.; Gryder, Berkley E.; Wachtel, Marco 分享 收藏
The Chromatin Remodeler CHD4 Sustains Ewing Sarcoma Cell Survival by Controlling Global Chromatin Architecture Marques, Joana Graca; Pavlovic, Blaz; Ngo, Quy A.; Pedot, Gloria; Roemmele, Michaela; Volken, Larissa; Kisele, Samanta; Perbet, Romain; Wachtel, Marco; Schafer, Beat W. 分享 收藏
RETRACTION: Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization (vol 27, 100784, 2022) (Retraction of Vol 27, art no 100784, 2022) Pedot, Gloria; Marques, Joana Graca; Ambuhl, Philip P.; Wachtel, Marco; Kasper, Stephanie; Ngo, Quy A.; Niggli, Felix K.; Schafer, Beat W. 分享 收藏
RETRACTION: Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization (Retraction of Vol 31, art no 100805, 2022) Pedot, Gloria; Marques, Joana Graca; Ambuehl, Philip P.; Wachtel, Marco; Kasper, Stephanie; Ngo, Quy A.; Niggli, Felix K.; Schaefer, Beat W. 分享 收藏
The ITCC-P4 sustainable platform of fully characterized PDXs supports the preclinical proof-of-concept drug testing of high-risk pediatric tumor models 完全表征的PDXs的ITCC-P4可持续平台支持高风险儿科肿瘤模型的临床前概念验证药物测试 Federico, Aniello; Gopisetty, Apurva; Surdez, Didier; Iddir, Yasmine; Saint-Charles, Alexandra; Wierzbinska, Justyna; Schlicker, Andreas; Volckmann, Richard; Zwijnenburg, Danny; Colombetti, Sara; Heidenreich, Olaf; Iradier, Fatima; Kovar, Heinrich; Klusmann, Jan-Henning; Debatin, Klaus-Michael; Bomken, Simon; Guttke, Christina; Hattersley, Maureen M.; Colland, Frederic; Strougo, Ashley; Guillen, Maria Jose; Chesler, Louis; Jones, Chris; da Costa, Maria Eugenia Marques; Scotlandi, Katia; Moro, Massimo; Schafer, Beat; Wachtel, Marco; Gojo, Johannes; Berger, Walter; Carcaboso, Angel Montero; Gurgen, Dennis; Hoffmann, Jens; Indersie, Emilie; Cairo, Stefano; Schueler, Julia; Huebener, Nicole; Schulte, Johannes H.; Molenaar, Jan J.; Geoerger, Birgit; Shields, David J.; Caron, Hubert N.; Vassal, Gilles; Stancato, Lou F.; Pfister, Stefan M.; Jager, Natalie; Koster, Jan; Kool, Marcel; Schleiermacher, Gudrun 分享 收藏
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Adult Low-Hypodiploid Acute Lymphoblastic Leukemia Emerges from Preleukemic TP53-Mutant Clonal Hematopoiesis Kim, Rathana; Bergugnat, Hugo; Larcher, Lise; Duchmann, Matthieu; Passet, Marie; Gachet, Stephanie; Cuccuini, Wendy; Lafage-Pochitaloff, Marina; Pastoret, Cedric; Grardel, Nathalie; Asnafi, Vahid; Schaefer, Beat W.; Delabesse, Eric; Itzykson, Raphael; Ades, Lionel; Hicheri, Yosr; Chalandon, Yves; Graux, Carlos; Chevallier, Patrice; Hunault, Mathilde; Leguay, Thibaut; Huguet, Francoise; Lheritier, Veronique; Dombret, Herve; Soulier, Jean; Rousselot, Philippe; Boissel, Nicolas; Clappier, Emmanuelle 分享 收藏
Molecular testing of rhabdomyosarcoma in clinical trials to improve risk stratification and outcome: A consensus view from European paediatric Soft tissue sarcoma Study Group, Children's Oncology Group and Cooperative Weichteilsarkom-Studiengruppe Hettmer, Simone; Linardic, Corinne M.; Kelsey, Anna; Rudzinski, Erin R.; Vokuhl, Christian; Selfe, Joanna; Ruhen, Olivia; Shern, Jack F.; Khan, Javed; Kovach, Alexander R.; Lupo, Philip J.; Gatz, Susanne A.; Schaefer, Beat W.; Volchenboum, Samuel; Minard-Colin, Veronique; Koscielniak, Ewa; Hawkins, Douglas S.; Bisogno, Gianni; Sparber-Sauer, Monika; Venkatramani, Rajkumar; Merks, Johannes H. M.; Shipley, Janet 分享 收藏
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