Wolfgang Löscher - Publications, H-index & Citations

The Discovery of Cenobamate: A Drug with High Efficacy in Drug-Resistant Epilepsy Cenobamate的发现：一种在药物难治性癫痫中具有高效力的药物

IF7.4

2026-06-18

OAAI

Wolfgang Löscher; Chris Rundfeldt; Eugen Trinka; Matthias Koepp; Pavel Klein

A consensus roadmap for post-traumatic epilepsy: Clinical biomarkers, research priorities, policy barriers, and pathways to interventional trials 创伤后癫痫的共识路线图：临床生物标志物、研究重点、政策障碍和干预试验路径

IF7.4

2026-04-08

OAAI

Yong Moon Choi; H. Steve White; Pavel Klein; Wolfgang Löscher

The Complexity and Challenges of Developing Effective Epilepsy Therapies: Lessons to be Learned from Comparing Cenobamate, Carisbamate, and Padsevonil 开发有效癫痫疗法复杂性与挑战：从比较Cenobamate、Carisbamate和Padsevonil中汲取的教训

IF6.6

2026-04-01

OAAI

Zanier, Elisa R.; Lisi, Ilaria; O'Loughlin, Elaine K.; Moro, Federico; Amorim, Edilberto; Brody, David L.; Correa, Daniel J.; Duncan, Dominique; Klein, Pavel; Kobeissy, Firas H.; Loescher, Wolfgang; Needham, Edward J.; Pitkanen, Asla; Pugh, Mary Jo; Somers, Jack; Vezzani, Annamaria; Wagner, Amy K.; Lubbers, Laura S.

Ranking of antiseizure medications in a panel of focal seizure models predicts their comparative efficacy in clinical add-on trials in drug-resistant focal epilepsy 抗癫痫药物在一系列局灶性癫痫模型中的排名预测其在药物难治性局灶性癫痫临床加用试验中的比较疗效

IF7.4

2026-03-31

OAAI

Wolfgang Löscher; H. Steve White; Pavel Klein

Seletracetam Revisited: A Missed Opportunity for Effective Epilepsy Therapy 塞来拉西坦再探：错失的有效癫痫治疗良机

IF6.6

2026-03-28

OAAI

Wolfgang Löscher; Pavel Klein

Academia, industry and the slow adoption of new treatments 学术界、工业界以及新疗法的缓慢采用

IF7.4

2026-03-03

OAAI

Wolfgang Löscher; Chris Rundfeldt; Eugen Trinka; Matthias Koepp; Pavel Klein

BRAIN

IF11.7

2025-11-01

PREAI

Klein, Pavel; Pong, Amanda; Koepp, Matthias; Loscher, Wolfgang; Sander, Josemir W.; Faught, Edward

Breaking optical barriers: Transparent polymeric hollow fibers for biomedical applications 突破光学屏障：用于生物医学应用的透明聚合物中空纤维

VIEW

IF8.5

2025-09-24

OAAI

Marián Mantecón-Oria; María J. Rivero; Wolfgang Löscher; Andreas Brachner; Winfried Neuhaus; Ane Urtiaga; Nazely Diban

Topiramate for the treatment of neonatal seizures and beyond 托吡酯在新生儿惊厥治疗中的应用及更广阔的应用

The human photosensitive epilepsy model for clinical proof-of-principle trials of novel antiseizure medications. 1. Use of the EEG in drug development and characteristics of the model 人类光敏性癫痫模型用于新型抗癫痫药物的临床原理验证试验。1. 药物开发中的EEG应用及模型特征

IF6.6

2025-07-31

OAAI

Wolfgang Löscher; Janet S. Soul

The human photosensitive epilepsy model for clinical proof-of-principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model 人光敏性癫痫模型用于新型抗惊厥药物的临床原理验证试验：2. 药物试验分析及模型预测价值

IF6.6

2025-05-24

OAAI

Dorothée Kasteleijn-Nolst Trenité; Wolfgang Löscher

Pharmacodynamic interactions between seletracetam and antiseizure comedications in the human photosensitivity model 塞来拉西坦与抗癫痫辅助药物在人类光敏性模型中的药效动力学相互作用

IF6.6

2025-05-10

OAAI

Wolfgang Löscher; Dorothée Kasteleijn-Nolst Trenité

Clinical trials of prevention of acquired epilepsy: New proof-of-concept approach to restart trials 获得性癫痫预防的临床试验：重启试验的新概念验证方法

IF6.6

2025-04-22

OAAI

Wolfgang Löscher; Armel Stockis; Pavel Klein; Dorothee Kasteleijn-Nolst Trenité

New epilepsy therapies in development 新型癫痫治疗药物正在研发中

IF6.6

2025-04-04

PREAI

Pavel Klein; Matthias Koepp; Alexander Rotenberg; Mustafa Q. Hameed; Wolfgang Löscher

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2024-07-22

PREAI

Klein, Pavel; Kaminski, Rafal M.; Koepp, Matthias; Loescher, Wolfgang

The impact of ATP-binding cassette transporters in the diseased brain: Context matters ATP结合盒转运蛋白在患病大脑中的影响: 背景很重要

CELL REPORTS MEDICINE

IF10.6

2024-06-01

OAAI

Baltira, Chrysiida; Aronica, Eleonora; Elmquist, William F.; Langer, Oliver; Loescher, Wolfgang; Sarkaria, Jann N.; Wesseling, Pieter; de Gooijer, Mark C.; van Tellingen, Olaf

Epilepsy and epileptiform activity in late-onset Alzheimer disease: clinical and pathophysiological advances, gaps and conundrums

NATURE REVIEWS NEUROLOGY

IF33.1

2024-02-14

PREAI

Kamondi, Anita; Grigg-Damberger, Madeleine; Loescher, Wolfgang; Tanila, Heikki; Horvath, Andras Attila

On hidden factors and design-associated errors that may lead to data misinterpretation: An example from preclinical research on the potential seasonality of neonatal seizures

Human brain microvascular endothelial cells release different types of P-glycoprotein-containing extracellular vesicles upon exposure to doxorubicin

IF6.6

2023-12-11

OAAI

Loescher, Wolfgang

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2023-11-01

PREAI

Osten, Felix; Loescher, Wolfgang; Gericke, Birthe

Animal Models of Drug-Resistant Epilepsy as Tools for Deciphering the Cellular and Molecular Mechanisms of Pharmacoresistance and Discovering More Effective Treatments

CELLS

IF5.2

2023-04-24

OAAI

Loescher, Wolfgang; White, H. Steve

Preclinical pharmacokinetics and tolerability of a novel meglumine-based parenteral solution of topiramate and topiramate combinations for treatment of status epilepticus