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收藏分享 收藏 分享 收藏 Safety, reactogenicity, and immunogenicity of MTBVAC in infants: a phase 2a randomised, double-blind, dose-defining trial in a TB endemic settingMTBVAC在婴儿中的安全性、反应原性和免疫原性：一项在结核病流行地区进行的2a期随机、双盲、剂量定义试验
Tameris, Michele; Rozot, Virginie; Imbratta, Claire; Geldenhuys, Hennie; Mendelsohn, Simon C.; Luabeya, Angelique Kany Kany; Shenje, Justin; Tredoux, Nicolette; Fisher, Michelle; Mulenga, Humphrey; Bilek, Nicole; Young, Carly; Veldsman, Ashley; Botes, Natasja; Thole, Jelle; Fritzell, Bernard; Mukherjee, Rajat; Jelsbak, Ingrid Murillo; Rodriguez, Esteban; Puentes, Eugenia; Doce, Juana; Marinova, Dessislava; Gonzalo-Asensio, Jesus; Aguilo, Nacho; Martin, Carlos; Scriba, Thomas J.; Hatherill, Mark 分享 收藏 Cytolytic γδ T-cells and IFNγ-producing CD4-lymphocytes characterise the early response to MTBVAC tuberculosis vaccine细胞毒性γδ T细胞和产生IFNγ的CD4淋巴细胞是MTBVAC结核疫苗早期反应的特征。Felgueres, Maria-Jose; Esteso, Gloria; Garcia-Jimenez, alvaro F.; Benguria, Alberto; Vazquez, Enrique; Aguilo, Nacho; Puentes, Eugenia; Dopazo, Ana; Murillo, Ingrid; Martin, Carlos; Rodriguez, Esteban; Reyburn, Hugh T.; Vales-Gomez, Mar 分享 收藏 分享 收藏 MTBVAC induces superior antibody titers and IgG avidity compared to BCG vaccination in non-human primatesPeralta-Alvarez, Marco Polo; Downward, Keya; White, Andrew; Redondo Azema, Hugo; Sibley, Laura; Sarfas, Charlotte; Morrison, Alexandra; Dennis, Mike; Diaz-Santana, Delia; Harris, Stephanie A.; Li, Shuailin; Puentes, Eugenia; Aguilo, Nacho; Martin, Carlos; Sharpe, Sally; McShane, Helen; Tanner, Rachel 分享 收藏 分享 收藏 分享 收藏 Low-dose M.tb infection but not BCG or MTBVAC vaccination enhances heterologous antibody titres in non-human primatesAlvarez, Marco Polo Peralta; Jones, Holly; Azema, Hugo Redondo; Davis, Chloe; White, Andrew D.; Sarfas, Charlotte; Dennis, Mike; Li, Shuailin; Wright, Daniel; Puentes, Eugenia; Kimuda, Simon; Belij-Rammerstorfer, Sandra; Aguilo, Nacho; Martin, Carlos; Sharpe, Sally; Mcshane, Helen; Tanner, Rachel 分享 收藏 Safety, reactogenicity and immunogenicity of MTBVAC in newborns in a TB endemic area: a phase 2a randomized, double-blind, dose-defining trialTameris, Michele; Barja, Sara; Rozot, Virginie; Imbratta, Claire; Musvosvi, Munyaradzi; Jelsbak, Ingrid Murillo; Geldenhuys, Hennie; Shenje, Justin; Luabeya, Angelique; Mendelsohn, Simon; Tredoux, Nicolette; Fisher, Michelle; Bilek, Nicole; Asma, Toefy; Mabwe, Simbarashe; Doce, Juana; Aguilo, Nacho; Marinova, Dessislava; Puentes, Eugenia; Martin, Carlos; Mukherjee, Rajat; Scriba, Thomas; Hatherill, Mark 分享 收藏 分享 收藏 分享 收藏 Intravenous administration of BCG in mice promotes natural killer and T cell-mediated antitumor immunity in the lungMoreo, Eduardo; Jarit-Cabanillas, Aitor; Robles-Vera, Inaki; Uranga, Santiago; Guerrero, Claudia; Gomez, Ana Belen; Mata-Martinez, Pablo; Minute, Luna; Araujo-Voces, Miguel; Felgueres, Maria Jose; Esteso, Gloria; Uranga-Murillo, Iratxe; Arias, Maykel; Pardo, Julian; Martin, Carlos; Vales-Gomez, Mar; del Fresno, Carlos; Sancho, David; Aguilo, Nacho 分享 收藏 分享 收藏 Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilliPhoPR双组分调节系统的传感器激酶中的自然突变调节祖先样结核杆菌的毒力Malaga, Wladimir; Payros, Delphine; Meunier, Eva; Frigui, Wafa; Sayes, Fadel; Pawlik, Alexandre; Orgeur, Mickael; Berrone, Celine; Moreau, Flavie; Mazeres, Serge; Gonzalo-Asensio, Jesus; Rengel, David; Martin, Carlos; Astarie-Dequeker, Catherine; Mourey, Lionel; Brosch, Roland; Guilhot, Christophe 分享 收藏 BCG-activation of leukocytes is sufficient for the generation of donor-independent innate anti-tumor NK and γδ T-cells that can be further expanded in vitroEsteso, Gloria; Felgueres, Maria Jose; Garcia-Jimenez, Alvaro F.; Reyburn-Vales, Christina; Benguria, Alberto; Vazquez, Enrique; Reyburn, Hugh T.; Aguilo, Nacho; Martin, Carlos; Puentes, Eugenia; Murillo, Ingrid; Rodriguez, Esteban; Vales-Gomez, Mar 分享 收藏 Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37RvAsai, Masanori; Li, Yanwen; Spiropoulos, John; Cooley, William; Everest, David J.; Kendall, Sharon L.; Martin, Carlos; Robertson, Brian D.; Langford, Paul R.; Newton, Sandra M. 分享 收藏 Novel intravesical bacterial immunotherapy induces rejection of BCG-unresponsive established bladder tumorsMoreo, Eduardo; Uranga, Santiago; Pico, Ana; Gomez, Ana Belen; Nardelli-Haefliger, Denise; del Fresno, Carlos; Murillo, Ingrid; Puentes, Eugenia; Rodriguez, Esteban; Vales-Gomez, Mar; Pardo, Julian; Sancho, David; Martin, Carlos; Aguilo, Nacho 分享 收藏 The Mycobacterium tuberculosis PhoPR virulence system regulates expression of the universal second messenger c-di-AMP and impacts vaccine safety and efficacy结核分枝杆菌PhoPR毒力系统调节通用第二信使c-di-amp的表达并影响疫苗的安全性和有效性Perez, Irene; Campos-Pardos, Elena; Diaz, Caridad; Uranga, Santiago; Sayes, Fadel; Vicente, Francisca; Aguilo, Nacho; Brosch, Roland; Martin, Carlos; Gonzalo-Asensio, Jesus 分享 收藏 
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