Alan J. Knox - Publications, H-index & Citations

Alan J. Knox

University of Nottingham

66H指数

379论文数

1.5W被引数

收录论文 139

发表时间

Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1β in human airway smooth muscle cells:: Involvement of different promoter elements, transcription factors, and histone H4 acetylation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

111

OAAI

Nie, M; Pang, LH; Inoue, H; Knox, AJ

Defective Histone Acetylation Is Responsible for the Diminished Expression of Cyclooxygenase 2 in Idiopathic Pulmonary Fibrosis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

164

OAAI

Coward, William R.; Watts, Keiria; Feghali-Bostwick, Carol A.; Knox, Alan; Pang, Linhua

Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis

JOURNAL OF CYSTIC FIBROSIS

IF6

2022-07-01

PREAI

Webb, Karmel; Camara, Miguel; Zain, Nur Masirah M.; Halliday, Nigel; Bruce, Kenneth D.; Nash, Edward F.; Whitehouse, Joanna L.; Knox, Alan; Forrester, Douglas; Smyth, Alan R.; Williams, Paul; Fogarty, Andrew; Barr, Helen L.

TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma

CLINICAL EPIGENETICS

IF4.4

2020-10-02

OAAI

Clifford, Rachel L.; Yang, Chen Xi; Fishbane, Nick; Patel, Jamie; MacIsaac, Julia L.; McEwen, Lisa M.; May, Sean T.; Castellanos-Uribe, Marcos; Nair, Parameswaran; Obeidat, Ma'en; Kobor, Michael S.; Knox, Alan J.; Hackett, Tillie-Louise

Airway epithelial cell isolation techniques affect DNA methylation profiles with consequences for analysis of asthma related perturbations to DNA methylation

SCIENTIFIC REPORTS

IF3.9

2019-10-08

OAAI

Clifford, Rachel L.; Patel, Jamie; MacIsaac, Julia L.; McEwen, Lisa M.; Johnson, Simon R.; Shaw, Dominick; Knox, Alan J.; Hackett, Tillie-Louise; Kobor, Michael S.

Epigenetic Changes in Airway Smooth Muscle as a Driver of Airway Inflammation and Remodeling in Asthma 气道平滑肌的表观遗传变化是哮喘气道炎症和重塑的驱动因素

CHEST

IF8.6

2019-04-01

PREAI

Kaczmarek, Klaudia A.; Clifford, Rachel L.; Knox, Alan J.

Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IF5.3

2018-04-01

OAAI

Coward, William R.; Brand, Oliver J.; Pasini, Alice; Jenkins, Gisli; Knox, Alan J.; Pang, Linhua

Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

CLINICAL EPIGENETICS

IF4.4

2018-03-05

OAAI

Clifford, Rachel L.; Fishbane, Nick; Patel, Jamie; MacIsaac, Julia L.; McEwen, Lisa M.; Fisher, Andrew J.; Brandsma, Corry-Anke; Nair, Parameswaran; Kobor, Michael S.; Hackett, Tillie-Louise; Knox, Alan J.

PINX1 and TERT Are Required for TNF-α-Induced Airway Smooth Muscle Chemokine Gene Expression

JOURNAL OF IMMUNOLOGY

IF3.4

2018-02-15

OAAI

Deacon, Karl; Knox, Alan J.

Role of Rho-Associated Coiled-Coil Forming Kinase Isoforms in Regulation of Stiffness-Induced Myofibroblast Differentiation in Lung Fibrosis

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IF5.3

2017-06-01

OAAI

Htwe, Su S.; Cha, Byung H.; Yue, Kan; Khademhosseini, Ali; Knox, Alan J.; Ghaemmaghami, Amir M.

Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: A longitudinal study 系统性烷基喹诺酮类药物对囊性纤维化铜绿假单胞菌的诊断和预后意义: 一项纵向研究

JOURNAL OF CYSTIC FIBROSIS

IF6

2017-03-01

OAAI

Barr, Helen L.; Halliday, Nigel; Barrett, David A.; Williams, Paul; Forrester, Douglas L.; Peckham, Daniel; Williams, Kate; Smyth, Alan R.; Honeybourne, David; Whitehouse, Joanna L.; Nash, Edward F.; Dewar, Jane; Clayton, Andrew; Knox, Alan J.; Camara, Miguel; Fogarty, Andrew W.

SUBERANILOHYDROXAMIC ACID (SAHA) INHIBITS COLLAGEN DEPOSITION IN A TRANSFORMING GROWTH FACTOR β1-DRIVEN PRECISION CUT LUNG SLICE (PCLS) MODEL OF PULMONARY FIBROSIS

THORAX

IF7.7

2016-11-15

OAAI

Brand, O. J.; Pasini, A.; Habgood, A.; Knox, A. J.; Jenkins, G.; Pang, L.

INVESTIGATING GENOME WIDE DNA METHYLATION IN AIRWAY SMOOTH MUSCLE CELLS FROM ASTHMATIC AND NON-ASTHMATIC DONORS

THORAX

IF7.7

2016-11-15

OAAI

Clifford, R. L.; Patel, J. K.; Shaw, D. E.; Knox, A. J.; Kobor, M. S.

EFFECT OF EPIGENETIC INHIBITORS ON LUNG FIBROBLAST PHENOTYPE CHANGE IN IDIOPATHIC PULMONARY FIBROSIS

THORAX

IF7.7

2016-11-15

OAAI

Pasini, A.; Brand, O. J.; Jenkins, G.; Knox, A. J.; Pang, L.

THE ROLE OF HISTONE ARGININE METHYLATION IN GENE EXPRESSION OF AIRWAY SMOOTH MUSCLE CELLS IN ASTHMA

THORAX

IF7.7

2016-11-15

OAAI

Kaczmarek, K. A.; Clifford, R. L.; Patel, J. K.; Shaw, D. E.; Dowden, J.; Knox, A. J.

INVESTIGATING GENOME WIDE DNA METHYLATION IN AIRWAY AND PARENCHYMAL FIBROBLASTS FROM HEALTHY INDIVIDUALS AND INDIVIDUALS WITH COPD

THORAX

IF7.7

2016-11-15

OAAI

Clifford, R. L.; Fishbane, N.; Rajasekar, P.; Fisher, A. J.; Kobor, M. S.; Knox, A. J.; Hackett, T. L.

SYSTEMIC ALKYL QUINOLONES AS NOVEL BIOMARKERS FOR PULMONARY EXACERBATIONS IN CYSTIC FIBROSIS: A VALIDATION STUDY

THORAX

IF7.7

2016-11-15

OAAI

Barr, H.; Fogarty, A.; Halliday, N.; Knox, A.; Quon, B.; Forrester, D.; Williams, P.; Barrett, D.; Camara, M.

Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33-mediated macrophage polarization and emphysema

SCIENCE SIGNALING

IF6.6

2016-10-25

OAAI

John, Alison E.; Wilson, Michael R.; Habgood, Anthony; Porte, Joanne; Tatler, Amanda L.; Stavrou, Anastasios; Miele, Gino; Jolly, Lisa; Knox, Alan J.; Takata, Masao; Offermanns, Stefan; Jenkins, R. Gisli

The pharmacokinetics and toxicity of morning vs. evening tobramycin dosing for pulmonary exacerbations of cystic fibrosis: A randomised comparison

JOURNAL OF CYSTIC FIBROSIS

IF6

2016-07-01

OAAI

Prayle, A. P.; Jain, K.; Touw, D. J.; Koch, B. C. P.; Knox, A. J.; Watson, A.; Smyth, A. R.

Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-04-01

OAAI

Tatler, Amanda L.; Habgood, Anthony; Porte, Joanne; John, Alison E.; Stavrou, Anastasios; Hodge, Emily; Kerama-Likoko, Cheryl; Violette, Shelia M.; Weinreb, Paul H.; Knox, Alan J.; Laurent, Geoffrey; Parfrey, Helen; Wolters, Paul John; Wallace, William; Alberti, Siegfried; Nordheim, Alfred; Jenkins, Gisli

研究方向