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Konstantin Leskov

University System of Ohio

H指数:22

被引数:2,730

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Reduction of the HIV-1 reservoir in T cells from people with HIV-1 on suppressive antiretroviral therapy using expanded natural killer cells

使用扩增的自然杀伤细胞减少接受抑制性抗逆转录病毒疗法的人的HIV-1感染者T细胞中的HIV-1储存库

IF4.7

2026-02-010

PRE

Interleukin-2 is a potent latency reversal agent in people with treated HIV-1

SCIENCE ADVANCES

IF12.5

2025-12-190

PRE

HIV infection reprogrammes CD4+ T cells for quiescence and entry into proviral latency

HIV感染使CD4+ T细胞重编程为静息状态并进入前病毒潜伏期

Nature Microbiology

IF19.4

2025-09-260

OAAI

Structural rearrangements in the nucleus localize latent HIV proviruses to a perinucleolar compartment supportive of reactivation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-04-261

OAAI

Single cell multiomic analysis reveals diabetes-associated β-cell heterogeneity driven by HNF1A

单细胞组学分析揭示由HNF1A驱动的糖尿病相关 β 细胞异质性

NATURE COMMUNICATIONS

IF15.7

2023-09-057

OAAI

Genomic profiling of HIV-1 integration in microglia cells links viral integration to the topologically associated domains

IF6.9

2023-02-0112

OA

The potential role of HIV-1 latency in promoting neuroinflammation and HIV-1-associated neurocognitive disorder

TRENDS IN IMMUNOLOGY

IF13.9

2022-08-0135

OA

Recruitment of the CoREST transcription repressor complexes by Nerve Growth factor IB-like receptor (Nurr1/NR4A2) mediates silencing of HIV in microglial cells

IF4.9

2022-07-0718

OAAI

Biogenesis of P-TEFb in CD4+ T cells to reverse HIV latency is mediated by protein kinase C (PKC)-independent signaling pathways

IF4.9

2021-09-1617

OAAI

Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress

EMBO MOLECULAR MEDICINE

IF8.3

2021-07-2031

OAAI

Single-cell lineage analysis reveals extensive multimodal transcriptional control during directed beta-cell differentiation

NATURE METABOLISM

IF20.8

2020-11-3043

OAAI

Human neuroblastoma cells rapidly enter cell cycle arrest and apoptosis following exposure to C-28 derivatives of the synthetic triterpenoid CDDO

CANCER BIOLOGY & THERAPY

IF4.6

2014-10-2747

OAAI

Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair

NUCLEIC ACIDS RESEARCH

IF13.1

2014-03-0341

OAAI

Low dose IR-induced IGF-1-sCLU expression: a p53-repressed expression cascade that interferes with TGFβ1 signaling to confer a pro-survival bystander effect

IF7.3

2012-03-0527

OAAI

CRM1 Protein-mediated Regulation of Nuclear Clusterin (nCLU), an Ionizing Radiation-stimulated, Bax-dependent Pro-death Factor

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-11-0138

OAAI

Efficient suppression of secretory clusterin levels by polymer-siRNA nanocomplexes enhances ionizing radiation lethality in human MCF-7 breast cancer cells in vitro

INTERNATIONAL JOURNAL OF NANOMEDICINE

IF6.5

2006-01-0148

OAAI

Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer

挑战与前景: clusterin在癌症发病机制、进展和治疗中的作用

CELL DEATH AND DIFFERENTIATION

IF15.4

2005-09-23324

OAAI

Delayed activation of insulin-like growth factor-1 receptor/Src/MAPK/Egr-1 signaling regulates clusterin expression, a pro-survival factor

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2005-04-01143

OAAI

Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation

IF7.3

2003-08-28242

OAAI

RETRACTED: Ku70 suppresses the apoptotic translocation of Bax to mitochondria (Retracted article. See vol 9, pg 480, 2007)

NATURE CELL BIOLOGY

IF19.1

2003-03-24354

PREAI