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收藏Predicting hERG repolarization power at 37°C from recordings at room temperature
Oliveira-Mendes, Barbara B. R.; Alameh, Malak; Montnach, Jerome; Ollivier, Beatrice; Gibaud, Solene; Feliciangeli, Sylvain; Lesage, Florian; Charpentier, Flavien; Loussouarn, Gildas; De Waard, Michel; Baro, Isabelle
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收藏A photoswitchable inhibitor of TREK channels controls pain in wild-type intact freely moving animals
Landra-Willm, Arnaud; Karapurkar, Ameya; Duveau, Alexia; Chassot, Anne Amandine; Esnault, Lucille; Callejo, Gerard; Bied, Marion; Hafner, Stephanie; Lesage, Florian; Wdziekonski, Brigitte; Baron, Anne; Fossat, Pascal; Marsollier, Laurent; Gasull, Xavier; Boue-Grabot, Eric; Kienzler, Michael A.; Sandoz, Guillaume
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收藏A standardised hERG phenotyping pipeline to evaluate KCNH2 genetic variant pathogenicity
Oliveira-Mendes, Barbara; Feliciangeli, Sylvain; Menard, Melissa; Chatelain, Frank; Alameh, Malak; Montnach, Jerome; Nicolas, Sebastien; Ollivier, Beatrice; Barc, Julien; Baro, Isabelle; Schott, Jean-Jacques; Probst, Vincent; Kyndt, Florence; Denjoy, Isabelle; Lesage, Florian; Loussouarn, Gildas; De Waard, Michel
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收藏TREK1 channel activation as a new analgesic strategy devoid of opioid adverse effects (vol 177, pg 4782, 2020)
Busserolles, Jerome; Ben Soussia, Ismail; Poucho, Laetitia; Marie, Nicolas; Melein, Mathieu; Devilliers, Maily; Judon, Celine; Schopp, Julien; Clemenceau, Loic; Poupon, Laura; Chapuy, Eric; Richard, Serge; Noble, Florence; Lesage, Florian; Sylvie, Ducki; Eschalier, Alain; Lolignier, Stephane
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收藏TREK1 channel activation as a new analgesic strategy devoid of opioid adverse effects
Busserolles, Jerome; Ben Soussia, Ismail; Pouchol, Laetitia; Marie, Nicolas; Meleine, Mathieu; Devilliers, Maily; Judon, Celine; Schopp, Julien; Clemenceau, Loic; Poupon, Laura; Chapuy, Eric; Richard, Serge; Noble, Florence; Lesage, Florian; Ducki, Sylvie; Eschalier, Alain; Lolignier, Stephane
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收藏Inhibition of histone deacetylation rescues phenotype in a mouse model of Birk-Barel intellectual disability syndrome抑制组蛋白去乙酰化可挽救birk-barel智力障碍综合征小鼠模型的表型
Cooper, Alexis; Butto, Tamer; Hammer, Niklas; Jagannath, Somanath; Fend-Guella, Desiree Lucia; Akhtar, Junaid; Radyushkin, Konstantin; Lesage, Florian; Winter, Jennifer; Strand, Susanne; Roeper, Jochen; Zechner, Ulrich; Schweiger, Susann
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收藏Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels
Ben Soussia, Ismail; El Mouridi, Sonia; Kang, Dawon; Leclercq-Blondel, Alice; Khoubza, Lamyaa; Tardy, Philippe; Zariohi, Nora; Gendrel, Marie; Lesage, Florian; Kim, Eun-Jin; Bichet, Delphine; Andrini, Olga; Boulin, Thomas
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收藏Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK
Royal, Perrine; Andres-Bilbe, Alba; Prado, Pablo Avalos; Verkest, Clement; Wdziekonski, Brigitte; Schaub, Sebastien; Baron, Anne; Lesage, Florian; Gasull, Xavier; Levitz, Joshua; Sandoz, Guillaume
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收藏Recombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels
Bobak, Nicole; Feliciangeli, Sylvain; Chen, Cheng-Chang; Ben Soussia, Ismail; Bittner, Stefan; Pagnotta, Sophie; Ruck, Tobias; Biel, Martin; Wahl-Schott, Christian; Grimm, Christian; Meuth, Sven G.; Lesage, Florian
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收藏Development of the First Two-Pore Domain Potassium Channel TWIK-Related K+ Channel 1-Selective Agonist Possessing in Vivo Antinociceptive Activity
Vivier, Delphine; Ben Soussia, Ismail; Rodrigues, Nuno; Lolignier, Stephane; Devilliers, Maily; Chatelain, Franck C.; Prival, Laetitia; Chapuy, Eric; Bourdier, Geoffrey; Bennis, Khalil; Lesage, Florian; Eschalier, Alain; Busserolles, Jerome; Ducki, Sylvie
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收藏The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size
Christensen, Alex Horby; Chatelain, Franck C.; Huttner, Inken G.; Olesen, Morten Sailing; Soka, Magdalena; Feliciangeli, Sylvain; Horvat, Claire; Santiago, Celine F.; Vandenberg, Jamie I.; Schmitt, Nicole; Olesen, Soren-Peter; Lesage, Florian; Fatkin, Diane
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收藏In cellulo phosphorylation induces pharmacological reprogramming of maurocalcin, a cell-penetrating venom peptide
Ronjat, Michel; Feng, Wei; Dardevet, Lucie; Dong, Yao; Al Khoury, Sawsan; Chatelain, Franck C.; Vialla, Virginie; Chahboun, Samir; Lesage, Florian; Darbon, Herve; Pessah, Isaac N.; De Waard, Michel
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