Darren L. Poole - Publications, H-index & Citations

Darren L. Poole

gsk

26H指数

76论文数

2.3K被引数

收录论文 39

发表时间

Chemist-aligned retrosynthesis by ensembling diverse inductive bias models 通过集成多样化的归纳偏置模型实现化学家对齐的逆向合成

Nature

IF48.5

2026-09-21

PREAI

Krzysztof Maziarz; Guoqing Liu; Felix Pultar; John Gardner; Tobias Gensch; Jean Helie; Hubert Misztela; Austin Tripp; Junren Li; Aleksei Kornev; Piotr Gaiński; Holger Hoefling; Mike Fortunato; Rishi Gupta; Andrew Baxter; Darren L. Poole; Jennifer M. Elward; Adrian Krzyzanowski; Peter Pogány; Stephen D. Pickett; Ian D. Wall; Christopher M. Bishop; Philip G. Humphreys; James A. Lumley; Mario P. Wiesenfeldt; Marwin H. S. Segler

Heterobenzyl Chlorides as Linchpins for C–H Arylation via Sequential C–H Chlorination/Cross-Electrophile Coupling

ACS Catalysis

IF13.1

2026-02-03

OAAI

Jack T. Floreancig; Marco A. Lopez; Allison R. Dick; Luana Cardinale; Nicole C. Goodwin; Darren L. Poole; Shannon S. Stahl

Selective Ni-Catalyzed Cross-Electrophile Coupling of Heteroaryl Chlorides and Aryl Bromides at 1:1 Substrate Ratio

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-12-23

PREAI

Su, Zhi-Ming; Zhu, Jieru; Poole, Darren L.; Rafiee, Mohammad; Paton, Robert S.; Weix, Daniel J.; Stahl, Shannon S.

eEtherification: An Electrochemical Strategy toward the Synthesis of Sterically Hindered Dialkyl Ethers from Activated Alcohols

ORGANIC LETTERS

IF5

2024-12-17

PREAI

Kiaku, Cyrille; Kaltenberger, Simon; Raydan, Daniel; Morlacci, Valerio; Claringbold, Bini; Goodall, Charles A. I.; Palombi, Laura; Poole, Darren L.; Lam, Kevin

Enantioselective [2π+2σ] Photocycloaddition Enabled by Brønsted Acid Catalyzed Chromophore Activation

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-11-07

PREAI

Plachinski, Ellie F.; Qian, Ruoyu Zoe; Villanueva, Rodrigo; Poole, Darren L.; Rosenthal, Tay; Yoon, Tehshik P.

Oxidative Rearomatization of Tetrahydroisoquinolines Promoted by Pyridine-N-oxide

ORGANIC LETTERS

IF5

2024-09-23

OAAI

Jenkins, Timothy C.; Poole, Darren L.; Donohoe, Timothy J.

Exploiting trans-Sulfinylation for the Synthesis of Diverse N-Alkyl Sulfinamides via Decarboxylative Sulfinamidation 利用反式亚磺酰化通过脱羧亚磺酰化合成多种N-烷基亚磺酰胺

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-08-22

OAAI

Andrews, Jonathan A.; Woodger, Russell G.; Palmer, Christopher F.; Poole, Darren L.; Willis, Michael C.

Manganese-Mediated Electrochemical Oxidation of Thioethers to Sulfoxides Using Water as the Source of Oxygen Atoms 使用水作为氧原子的锰介导的硫醚电化学氧化为亚砜

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-07-23

OAAI

Hoque, Md Asmaul; Jiang, Tianxiao; Poole, Darren L.; Stahl, Shannon S.

Diastereodivergent nucleophile-nucleophile alkene chlorofluorination

NATURE CHEMISTRY

IF20.2

2024-07-01

OAAI

Doobary, Sayad; Lacey, Andrew J. D.; Sweeting, Stephen G.; Coppock, Sarah B.; Caldora, Henry P.; Poole, Darren L.; Lennox, Alastair J. J.

Structure- and Property-Based Optimization of Efficient Pan-Bromodomain and Extra Terminal Inhibitors to Identify Oral and Intravenous Candidate I-BET787

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-06-12

PREAI

Hirst, David J.; Bamborough, Paul; Al-Mahdi, Niam; Angell, Davina C.; Barnett, Heather A.; Baxter, Andrew; Bit, Rino A.; Brown, Jack A.; Chung, Chun-wa; Craggs, Peter D.; Davis, Robert P.; Demont, Emmanuel H.; Ferrie, Alan; Gordon, Laurie J.; Harada, Isobel; Ho, Tim C. T.; Holyer, Ian D.; Hooper-Greenhill, Edward; Jones, Katherine L.; Lindon, Matthew J.; Lovatt, Cerys; Lugo, David; Maller, Claire; Mcgonagle, Grant; Messenger, Cassie; Mitchell, Darren J.; Pascoe, David D.; Patel, Vipulkumar K.; Patten, Christopher; Poole, Darren L.; Shah, Rishi R.; Rioja, Inmaculada; Stafford, Kayleigh A. J.; Tape, Daniel; Taylor, Simon; Theodoulou, Natalie H.; Tomlinson, Laura; Wall, Ian D.; Wellaway, Christopher R.; White, Gemma; Prinjha, Rab K.; Humphreys, Philip G.

Organometallic Bridge Diversification of Bicyclo[1.1.1]pentanes

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2024-01-10

PREAI

Anderson, Joseph M.; Poole, Darren L.; Cook, Gemma C.; Murphy, John A.; Measom, Nicholas D.

Photocatalytic Carboxylate to Sulfinamide Switching Delivers a Divergent Synthesis of Sulfonamides and Sulfonimidamides

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-09-22

OAAI

Andrews, Jonathan A.; Kalepu, Jagadeesh; Palmer, Christopher F.; Poole, Darren L.; Christensen, Kirsten E.; Willis, Michael C.

eHydrogenation: Hydrogen-free Electrochemical Hydrogenation

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2023-08-16

OAAI

Russo, Camilla; Leech, Matthew C.; Walsh, Jamie M.; Higham, Joe I.; Giannessi, Lisa; Lambert, Emmanuelle; Kiaku, Cyrille; Poole, Darren L.; Mason, Joseph; Goodall, Charles A. I.; Devo, Perry; Giustiniano, Mariateresa; Radi, Marco; Lam, Kevin

eFluorination of Activated Alcohols Using Collidinium Tetrafluoroborate

ORGANIC LETTERS

IF5

2023-05-19

PREAI

Kiaku, Cyrille; Martinage, Dorian; Sicim, Yasemin; Leech, Matthew C.; Walsh, Jamie M.; Poole, Darren L.; Mason, Joseph; Goodall, Iain C. A.; Devo, Perry; Lam, Kevin

Bridge Heteroarylation of Bicyclo[1.1.1]pentane Derivatives

ORGANIC LETTERS

IF5

2023-03-17

OAAI

Anderson, Joseph M.; Measom, Nicholas D.; Murphy, John A. .; Poole, Darren L.

eFluorination Using Cheap and Readily Available Tetrafluoroborate Salts

ORGANIC LETTERS

IF5

2023-03-01

OAAI

Leech, Matthew C.; Nagornii, Dmitrii; Walsh, Jamie M.; Kiaku, Cyrille; Poole, Darren L.; Mason, Joseph; Goodall, Iain C. A.; Devo, Perry; Lam, Kevin

Electronically Ambivalent Hydrodefluorination of Aryl-CF3 groups enabled by Electrochemical Deep-Reduction on a Ni Cathode

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2023-02-10

OAAI

Box, John R.; Avanthay, Mickael E.; Poole, Darren L.; Lennox, Alastair J.

Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-11-15

OAAI

Humphreys, Philip G.; Anderson, Niall A.; Bamborough, Paul; Baxter, Andrew; Chung, Chun-wa; Cookson, Rosa; Craggs, Peter D.; Dalton, Toryn; Fournier, Julie C. L.; Gordon, Laurie J.; Gray, Heather F.; Gray, Matthew W.; Gregory, Richard; Hirst, David J.; Jamieson, Craig; Jones, Katherine L.; Kessedjian, Hripsimee; Lugo, David; McGonagle, Grant; Patel, Vipulkumar K.; Patten, Christopher; Poole, Darren L.; Prinjha, Rab K.; Ramirez-Molina, Cesar; Rioja, Inmaculada; Seal, Gail; Stafford, Kayleigh A. J.; Shah, Rishi R.; Tape, Daniel; Theodoulou, Natalie H.; Tomlinson, Laura; Ukuser, Sabri; Wall, Ian D.; Wellaway, Natalie; White, Gemma

The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway

SCIENTIFIC REPORTS

IF3.9

2022-03-17

OAAI

Carlile, Graeme W.; Yang, Qi; Matthes, Elizabeth; Liao, Jie; Birault, Veronique; Sneddon, Helen F.; Poole, Darren L.; Hall, Callum J.; Hanrahan, John W.; Thomas, David Y.

Electrochemical Synthesis of Isoxazolines: Method and Mechanism

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2022-02-10

OAAI

Holman, Samuel D. L.; Wills, Alfie G.; Fazakerley, Neal J.; Poole, Darren L.; Coe, Diane M.; Berlouis, Leonard A.; Reid, Marc

研究方向