Demet Araç - Publications, H-index & Citations

Demet Araç

the university of chicago

32H指数

97论文数

5.3K被引数

收录论文 36

发表时间

The teneurin TEN-1 and its ligand LRON-11 support microbiota-induced neuroprotection and mechanosensory function in C. elegansteneurin TEN-1及其配体LRON-11支持微生物组诱导的神经保护和机械感觉功能在C. elegans中

Current Biology

IF7.5

2026-09-21

OAAI

Jingxian Li; Juan Pablo Castillo; Shouqiang Cheng; Indya Weathers; Wioletta I. Nawrocka; Jorge Alvarado; Minglei Zhao; Andrea Calixto; Engin Özkan; Demet Araç

Structural basis and functional roles for Toll-like receptor binding to Latrophilin in C. elegans development 秀丽隐杆线虫发育中Toll样受体与Latrophilin结合的结构基础和功能作用

Nature Structural & Molecular Biology

IF10.1

2025-06-30

PREAI

Gabriel Carmona-Rosas; Jingxian Li; Jayson J. Smith; Wioletta I. Nawrocka; Shouqiang Cheng; Elana E. Baltrusaitis; Minglei Zhao; Demet Araç; Paschalis Kratsios; Engin Özkan

Structural basis for regulation of CELSR1 by a compact module in its extracellular region CELSR1受其胞外区紧凑模块调控的结构基础

NATURE COMMUNICATIONS

IF15.7

2025-04-28

OAAI

Bandekar, Sumit J.; Garbett, Krassimira; Kordon, Szymon P.; Dintzner, Ethan E.; Li, Jingxian; Shearer, Tanner; Sando, Richard C.; Arac, Demet

Structural Basis for Regulation of CELSR1 by a Compact Module in Its Extracellular Region CELSR1被其胞外区一个紧凑模块调控的结构基础

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2025-03-01

PREAI

Bandekar, Sumit; Garbett, Krassimira; Kordon, Szymon P.; Dintzner, Ethan; Li, Jingxian; Shearer, Tanner; Sando, Richard; Arac, Demet

Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function

NATURE COMMUNICATIONS

IF15.7

2024-12-04

OAAI

Kordon, Szymon P.; Cechova, Kristina; Bandekar, Sumit J.; Leon, Katherine; Dutka, Przemyslaw; Siffer, Gracie; Kossiakoff, Anthony A.; Vafabakhsh, Reza; Arac, Demet

The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms

CELL REPORTS

IF6.9

2023-06-01

OAAI

Bui, Duy Lan Huong; Roach, Andrew; Li, Jingxian; Bandekar, Sumit J.; Orput, Elizabeth; Raghavan, Ritika; Arac, Demet; Sando, Richard C.

The structure of fly Teneurin-m reveals an asymmetric self-assembly that allows expansion into zippers 苍蝇Teneurin-m的结构揭示了一个不对称的自组装，允许扩展成拉链

EMBO REPORTS

IF6.2

2023-05-11

OAAI

Li, Jingxian; Bandekar, Sumit J. J.; Arac, Demet

Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder 合成粘合剂对粘附GPCR ADGRL3/Latrophilin3的同工型和配体特异性调节

NATURE COMMUNICATIONS

IF15.7

2023-02-06

OAAI

Kordon, Szymon P.; Dutka, Przemyslaw; Adamska, Justyna M.; Bandekar, Sumit J.; Leon, Katherine; Erramilli, Satchal K.; Adams, Brock; Li, Jingxian; Kossiakoff, Anthony A.; Arac, Demet

Cellular Communication via Adhesion

FASEB JOURNAL

IF4.2

2021-05-14

PREAI

Arac, Demet

Specific and direct modulation of the interaction between adhesion GPCR GPR56/ADGRG1 and tissue transglutaminase 2 using synthetic ligands 使用合成配体特异性和直接调节粘附GPCR GPR56/ADGRG1和组织转谷氨酰胺酶2之间的相互作用

SCIENTIFIC REPORTS

IF3.9

2020-10-09

OAAI

Salzman, Gabriel S.; Zhang, Shu; Fernandez, Celia G.; Ara, Demet; Koide, Shohei

Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism

NATURE COMMUNICATIONS

IF15.7

2020-05-01

OAAI

Li, Jingxian; Xie, Yuan; Cornelius, Shaleeka; Jiang, Xian; Sando, Richard; Kordon, Szymon P.; Pan, Man; Leon, Katherine; Sudhof, Thomas C.; Zhao, Minglei; Arac, Demet

Cellular Communication via Adhesion

FASEB JOURNAL

IF4.2

2020-04-15

OAAI

Arac, Demet

Structural basis for adhesion G protein-coupled receptor Gpr126 function

NATURE COMMUNICATIONS

IF15.7

2020-01-10

OAAI

Leon, Katherine; Cunningham, Rebecca L.; Riback, Joshua A.; Feldman, Ezra; Li, Jingxian; Sosnick, Tobin R.; Zhao, Minglei; Monk, Kelly R.; Arac, Demet

Teneurin Structure: Splice Variants of a Bacterial Toxin Homolog Specifies Synaptic Connections

FRONTIERS IN NEUROSCIENCE

IF3.2

2019-08-07

OAAI

Arac, Demet; Li, Jingxian

The expanding functional roles and signaling mechanisms of adhesion G protein-coupled receptors 粘附g蛋白偶联受体功能的扩展和信号机制

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

IF4.8

2019-06-06

OAAI

Morgan, Rory K.; Anderson, Garret R.; Arac, Demet; Aust, Gabriela; Balenga, Nariman; Boucard, Antony; Bridges, James P.; Engel, Felix B.; Formstone, Caroline J.; Glitsch, Maike D.; Gray, Ryan S.; Hall, Randy A.; Hsiao, Cheng-Chih; Kim, Hee-Yong; Knierim, Alexander B.; Kusuluri, Deva Krupakar; Leon, Katherine; Liebscher, Ines; Piao, Xianhua; Proemel, Simone; Scholz, Nicole; Srivastava, Swati; Thor, Doreen; Tolias, Kimberley F.; Ushkaryov, Yuri A.; Vallon, Mario; Van Meir, Erwin G.; Vanhollebeke, Benoit; Wolfrum, Uwe; Wright, Kevin M.; Monk, Kelly R.; Mogha, Amit

Teneurins and latrophilins: two giants meet at the synapse Teneurins和latrophilins: 两个巨人在突触相遇

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2019-02-01

OAAI

Arac, Demet; Li, Jingxian

Stachel-independent modulation of GPR56/ADGRG1 signaling by synthetic ligands directed to its extracellular region

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-09-05

OAAI

Salzman, Gabriel S.; Zhang, Shu; Gupta, Ankit; Koide, Akiko; Koide, Shohei; Arac, Demet

Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains GPR56/ADGRG1通过其选择性剪接的胞外结构域进行调控的结构基础

NEURON

IF15

2016-09-01

OAAI

Salzman, Gabriel S.; Ackerman, Sarah D.; Ding, Chen; Koide, Akiko; Leon, Katherine; Luo, Rong; Stoveken, Hannah M.; Fernandez, Celia G.; Tall, Gregory G.; Piao, Xianhua; Monk, Kelly R.; Koide, Shohei; Arac, Demet

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors 国际基础与临床药理学联合会。XCIV。粘附g蛋白偶联受体

PHARMACOLOGICAL REVIEWS

IF17.3

2015-04-01

414

OAAI

Hamann, Joerg; Aust, Gabriela; Arac, Demet; Engel, Felix B.; Formstone, Caroline; Fredriksson, Robert; Hall, Randy A.; Harty, Breanne L.; Kirchhoff, Christiane; Knapp, Barbara; Krishnan, Arunkumar; Liebscher, Ines; Lin, Hsi-Hsien; Martinelli, David C.; Monk, Kelly R.; Peeters, Miriam C.; Piao, Xianhua; Proemel, Simone; Schoeneberg, Torsten; Schwartz, Thue W.; Singer, Kathleen; Stacey, Martin; Ushkaryov, Yuri A.; Vallon, Mario; Wolfrum, Uwe; Wright, Mathew W.; Xu, Lei; Langenhan, Tobias; Schoeith, Helgi B.

New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors 一类粘附g蛋白偶联受体的新功能和信号机制

ANNALS REPORTS

IF0

2014-11-25

OAAI

Liebscher, Ines; Ackley, Brian; Arac, Demet; Ariestanti, Donna M.; Aust, Gabriela; Bae, Byoung-il; Bista, Bigyan R.; Bridges, James P.; Duman, Joseph G.; Engel, Felix B.; Giera, Stefanie; Goffinet, Andre M.; Hall, Randy A.; Hamann, Jorg; Hartmann, Nicole; Lin, Hsi-Hsien; Liu, Mingyao; Luo, Rong; Mogha, Amit; Monk, Kelly R.; Peeters, Miriam C.; Proemel, Simone; Ressl, Susanne; Schioth, Helgi B.; Sigoillot, Severine M.; Song, Helen; Talbot, William S.; Tall, Gregory G.; White, James P.; Wolfrum, Uwe; Xu, Lei; Piao, Xianhua

研究方向