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PI3Kγ inhibition drives M1 macrophage differentiation and synergizes with PD-L1 blockade to improve survival in poorly immunogenic head and neck squamous cell carcinoma Jordanides, Pete P.; Jagadeesha, Sushmitha; Upadhaya, Puja; Ryan, Nathan M.; Anderson, Kelvin; Lamenza, Felipe F.; Shrestha, Suvekshya; Siddiqui, Arham; Bopp, Anna R.; Pracha, Sherefuddin H.; Roth, Peyton; Kehres, Reegan; Mo, Xiaokui; Oghumu, Steve 分享 收藏
SREBP-1 upregulates SOAT1 to promote tumor growth by preventing lipotoxicity SREBP-1通过阻止脂otoxicity而上调SOAT1以促进肿瘤生长。 Zhong, Yaogang; Mazik, Logan; Su, Huali; Chiang, Cheng-Yao; Geng, Feng; Mo, Xiaokui; Wang, Qiang; Kou, Yongjun; Chakravarti, Arnab; Wang, Qi-En; Guo, Deliang 分享 收藏
Epigenetic Modulation, Intratumoral Microbiome, and Immunity in Early-Onset Colorectal Cancer Jin, Ning; Hoyd, Rebecca; Yilmaz, Ayse S.; Zhu, Jiangjiang; Liu, Yunzhou; Jagjit Singh, Malvenderjit S.; Grencewicz, Dennis J.; Mo, Xiaokui; Kalady, Matthew F.; Rosenberg, Daniel W.; Dravillas, Caroline E.; Singer, Eric A.; Carpten, John D.; Chan, Carlos H. F.; Churchman, Michelle L.; Denko, Nicholas; Di Clemente, Frances; Dodd, Rebecca D.; Eljilany, Islam; Fei, Naomi; Hardikar, Sheetal; Ikeguchi, Alexandra P.; Ma, Anjun; Ma, Qin; Mccarter, Martin D.; Osman, Afaf E. G.; Riedlinger, Gregory; Robinson, Lary A.; Schneider, Bryan P.; Tarhini, Ahmad A.; Tinoco, Gabriel; Figueiredo, Jane C.; Zakharia, Yousef; Ulrich, Cornelia M.; Tan, Aik Choon; Spakowicz, Daniel 分享 收藏
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Extracellular Vesicular Delta-Like Ligand 3 and Subtype Transcription Factors for Small Cell Lung Cancer Diagnosis 细胞外囊泡 Delta-Like 配体 3 及小细胞肺癌诊断的亚型转录因子 Li, H; Chiang, CL; Kwak, KJ; Lee, HL; Wang, XY; Romano, G; Saviana, M; Toft, R; Cheng, TS; Chang, YH; Hsiang, BD; Liu, GW; Mo, XK; Ma, YF; Pan, JJ; Rima, XY; Kim, TN; Reategui, E; Shen, CN; Chu, YS; Croce, C; Chang, PMH; Yeh, YC; Carbone, DP; Huang, CYF; Chiang, CL; Nana-Sinkam, P; Lee, LJ 分享 收藏
Targeting PGM3 abolishes SREBP-1 activation-hexosamine synthesis feedback regulation to effectively suppress brain tumor growth 靶向PGM3消除了SREBP-1激活-己糖胺合成反馈调控，从而有效抑制脑肿瘤生长。 Su, Huali; Zhong, Yaogang; He, Liqing; Geng, Feng; Yin, Xinmin; Kou, Yongjun; Chiang, Cheng-Yao; Mo, Xiaokui; Fan, Yunzhou; Liu, Yanwei; Wang, Qiang; Magaki, Shino; Cloughesy, Timothy F.; Lefai, Etienne; Yong, William H.; Chakravarti, Arnab; Zhang, Xiang; Guo, Deliang 分享 收藏
TARGETING PGM3 TO INHIBIT HEXOSAMINE PRODUCTION IS AN EFFECTIVE APPROACH TO TREAT GLIOBLASTOMA Su, Huali; Zhong, Yaogang; Geng, Feng; Fan, Yunzhou; Kou, Yongjun; Chiang, Cheng-yao; Mo, Xiaokui; Magaki, Shino; Cloughesy, Timothy F.; Lefai, Etienne; Yong, William H.; Chakravarti, Arnab; Guo, Deliang 分享 收藏
INCREASING GLUTAMINE UPTAKE-LIPOGENESIS AXIS PROMOTES TUMOR RESISTANCE TO LYSOSOME INHIBITION Zhong, Yaogang; Geng, Feng; Mazik, Logan; Yin, Xinmin; Becker, Aline Paixao; Mohammed, Shabber; Su, Huali; Xing, Enming; Kou, Yongjun; Chiang, Chengyao; Fan, Yunzhou; Li, Pui-Kai; Mo, Xiaokui; Lefai, Etienne; He, Liqing; Cheng, Xiaolin; Zhang, Xiang; Chakravarti, Arnab; Guo, Deliang 分享 收藏
ONCOGENIC STAT3 PROMOTES TUMOR GROWTH VIA STIMULATION THE SCAP- AND SREBP-1-REGULATED LIPOGENIC PATHWAY 致癌性STAT3通过刺激SCAP和SREBP-1-REGULATED脂肪生成途径促进肿瘤生长 Fan, Yunzhou; Zhang, Rui; Wang, Chao; Pan, Meixia; Geng, Feng; Zhong, Yaogang; Su, Huali; Kou, Yongjun; Mrinalini, Rajeev; Mo, Xiaokui; Han, Xianlin; Lefai, Etienne; Guo, Deliang 分享 收藏
Intestinal-level anti-inflammatory bioactivities of whole wheat: Rationale, design, and methods of a randomized, controlled, crossover dietary trial in adults with prediabetes Cao, Sisi; Pierson, Jillian T.; Bond, Ariana H.; Zhang, Shiqi; Gold, Andrew; Zhang, Huan; Zamary, Kaitlyn M.; Moats, Palmer; Teegarden, Matthew D.; Peterson, Devin G.; Mo, Xiaokui; Zhu, Jiangjiang; Bruno, Richard S. 分享 收藏
A Phase 2 Trial of Primary Tumor Stereotactic Body Radiation Therapy Boost Before Concurrent Chemoradiation for Locally Advanced Non-Small Cell Lung Cancer Williams, Terence M.; Miller, Eric; Welliver, Meng; Brownstein, Jeremy; Otterson, Gregory; Owen, Dwight; Haglund, Karl; Shields, Peter; Bertino, Erin; Presley, Carolyn; He, Kai; Jacob, Naduparambil K.; Walston, Steve; Pan, Jeff; Yang, Xiangyu; Knopp, Michael; Essan, Jean Koutou; McElroy, Joseph; Mo, Xiaokui; McElroy, Sohyun; Carbone, David; Bazan, Jose 分享 收藏
Circumventing resistance within the Ewing sarcoma microenvironment by combinatorial innate immunotherapy 通过组合先天免疫疗法规避尤文肉瘤微环境中的耐药性 Luo, Wen; Hoang, Hai; Zhu, Hongwen; Miller, Katherine; Mo, Xiaokui; Eguchi, Shiori; Tian, Meijuan; Liao, Yanling; Ayello, Janet; Rosenblum, Jeremy M.; Marcondes, Mario; Currier, Mark; Mardis, Elaine; Cripe, Timothy; Lee, Dean; Cairo, Mitchell S. 分享 收藏
Combinatorial targeting of glutamine metabolism and lysosomal-based lipid metabolism effectively suppresses glioblastoma Zhong, Yaogang; Geng, Feng; Mazik, Logan; Yin, Xinmin; Becker, Aline Paixao; Mohammed, Shabber; Su, Huali; Xing, Enming; Kou, Yongjun; Chiang, Cheng-Yao; Fan, Yunzhou; Guo, Yongchen; Wang, Qiang; Li, Pui-Kai; Mo, Xiaokui; Lefai, Etienne; He, Liqing; Cheng, Xiaolin; Zhang, Xiang; Chakravarti, Arnab; Guo, Deliang 分享 收藏
LP-118 is a novel B-cell lymphoma 2 / extra-large inhibitor that demonstrates efficacy in models of venetoclax-resistant chronic lymphocytic leukemia Ravikrishnan, Janani; Diaz-Rohena, Daisy Y.; Muhowski, Elizabeth; Mo, Xiaokui; Lai, Tzung-Huei; Misra, Shrilekha; Williams, Charmelle D.; Sanchez II, John R.; Mitchell, Andrew; Satpati, Suresh; Perry, Elizabeth; Kaufman, Tierney; Liu, Chaomei; Lozanski, Arletta; Lozanski, Gerard; Rogers, Kerry A.; Kittai, Adam S.; Bhat, Seema A.; Collins, Mary C.; Davids, Matthew S.; Jain, Nitin; Wierda, William G.; Lapalombella, Rosa; Byrd, John C.; Tan, Fenlai; Chen, Yi; Chen, Yu; Shen, Yue; Anthony, Stephen P.; Woyach, Jennifer A.; Sampath, Deepa 分享 收藏
Combinatorial macrophage induced innate immunotherapy against Ewing sarcoma: Turning Two Keys simultaneously Luo, Wen; Hoang, Hai; Miller, Katherine E.; Zhu, Hongwen; Xu, Serena; Mo, Xiaokui; Garfinkle, Elizabeth A. R.; Costello, Heather; Wijeratne, Saranga; Chemnitz, Wiebke; Gandhi, Ronan; Liao, Yanling; Ayello, Janet; Gardenswartz, Aliza; Rosenblum, Jeremy M.; Cassady, Kevin A.; Mardis, Elaine R.; Lee, Dean A.; Cripe, Timothy P.; Cairo, Mitchell S. 分享 收藏
Siglec-6 as a therapeutic target for cell migration and adhesion in chronic lymphocytic leukemia Nunes, Jessica; Tafesse, Rakeb; Mao, Charlene; Purcell, Matthew; Mo, Xiaokui; Zhang, Liwen; Long, Meixiao; Cyr, Matthew G.; Rader, Christoph; Muthusamy, Natarajan 分享 收藏
Enhanced IL-12 transgene expression improves oncolytic viroimmunotherapy Kim, Yeaseul; Saini, Uksha; Kim, Doyeon; Hernandez-Aguirre, Ilse; Hedberg, Jack; Martin, Alexia; Mo, Xiaokui; Cripe, Timothy P.; Markert, James; Cassady, Kevin A.; Dhital, Ravi 分享 收藏
STAT3 activation of SCAP-SREBP-1 signaling upregulates fatty acid synthesis to promote tumor growth STAT3激活SCAP-SREBP-1信号上调脂肪酸合成促进肿瘤生长 Fan, Yunzhou; Zhang, Rui; Wang, Chao; Pan, Meixia; Geng, Feng; Zhong, Yaogang; Su, Huali; Kou, Yongjun; Mo, Xiaokui; Lefai, Etienne; Han, Xianlin; Chakravarti, Arnab; Guo, Deliang 分享 收藏
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