David E. MacHugh - Publications, H-index & Citations

David E. MacHugh

UCD

53H指数

256论文数

1.1W被引数

收录论文 64

发表时间

Genetic control of the transcriptional response to active tuberculosis disease and treatment 活动性结核病及治疗对转录反应的遗传调控

Communications Medicine

IF6.3

2026-07-29

OAAI

John F. O’Grady; Alexander S. Leonard; Houcheng Li; Lingzhao Fang; Hubert Pausch; Isobel C. Gormley; Stephen. V. Gordon; David E. MacHugh

Integrative genome-wide association study and transcriptomic analysis to identify candidate genes and pathways for heterophil and lymphocyte traits in white-feathered broilers

Poultry Science

IF4.2

2026-01-08

OAAI

Jumei Zheng; Qiao Wang; John F. O’Grady; Zixuan Wang; Man Deng; Jin Zhang; Xiang Li; Yuqing Zhu; David E. MacHugh; Guiping Zhao

Age-induced gene expression in Thoroughbred horse skeletal muscle highlights genes that enhance muscle architecture and function 年龄诱导的纯种马骨骼肌基因表达突出了增强肌肉结构和功能的基因

Gene

IF2.4

2025-12-15

PREAI

Mian Feng; Thomas J. Hall; David E. MacHugh; Lisa M. Katz; Emmeline W. Hill

Epigenetic regulation of the immune response to Mycobacterium bovis infection in cattle: potential implications for diagnostic test sensitivity 牛分枝杆菌(Mycobacterium bovis)感染后，牛体内免疫反应的表观遗传调控：对诊断试验敏感性的潜在影响

Tuberculosis

IF2.9

2025-10-10

OAAI

Eamonn Gormley; David E. MacHugh; Kieran G. Meade

A multi-tissue single-cell expression atlas in cattle 牛的多组织单细胞表达图谱

Nature Genetics

IF0

2025-09-05

OAAI

Bo Han; Houcheng Li; Weijie Zheng; Qi Zhang; Ao Chen; Senlin Zhu; Tao Shi; Fei Wang; Dong Zou; Yu Song; Wen Ye; Aixia Du; Yihan Fu; Minghui Jia; Zhonghao Bai; Zhixiang Yuan; Wansheng Liu; Wenbin Tuo; Jayne C. Hope; David E. MacHugh; John F. O’Grady; Ole Madsen; Goutam Sahana; Yonglun Luo; Lin Lin; Congjun Li; Zexi Cai; Bingjie Li; Jinming Huang; Lin Liu; Zhang Zhang; Zhu Ma; Yali Hou; George E. Liu; Yu Jiang; Hui-zeng Sun; Lingzhao Fang; Dongxiao Sun

Single-cell multiomics reveals multiple adipogenic pathways and diverse multilineage specializations during embryonic fat tail morphogenesis 单细胞多组学揭示了胚胎脂肪尾形态发生过程中多条脂肪生成通路和多样的多谱系分化特化现象。

iScience

IF4.1

2025-09-03

OAAI

Jiangang Han; Sijia Ma; Qiuxia Wei; Zhengwei Zhao; Yuhetian Zhao; Yabin Pu; Qianjun Zhao; Xiaohong He; Yuehui Ma; David E. MacHugh; Lin Jiang

Transcriptomics analysis of the bovine endometrium during the perioestrus period (vol 20, e0324686, 2025)牛子宫内膜围发情期转录组学分析（vol 20, e0324686, 2025）

PLOS ONE

IF2.6

2025-05-20

OAAI

Alfattah, Mohammed A.; Correia, Carolina N.; Browne, John A.; McGettigan, Paul A.; Pluta, Katarzyna; Carrington, Stephen D.; MacHugh, David E.; Irwin, Jane A.

Integrative genomics sheds light on the immunogenetics of tuberculosis in cattle 整合基因组学为牛结核病的免疫遗传学提供了见解。

COMMUNICATIONS BIOLOGY

IF5.1

2025-03-24

OAAI

O'Grady, John F.; Mchugo, Gillian P.; Ward, James A.; Hall, Thomas J.; O'Donnell, Sarah L. Faherty; Correia, Carolina N.; Browne, John A.; Mcdonald, Michael; Gormley, Eamonn; Riggio, Valentina; Prendergast, James G. D.; Clark, Emily L.; Pausch, Hubert; Meade, Kieran G.; Gormley, Isobel C.; Gordon, Stephen V.; Machugh, David E.

Functional validation to explore the protective role of miR-223 in Staphylococcus aureus-induced bovine mastitis

JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY

IF6.5

2025-03-04

OAAI

Liu, Xueqin; Mi, Siyuan; Dari, Gerile; Chen, Siqian; Song, Jiuzhou; Machugh, David E.; Yu, Ying

Short communication: Genomic prediction based on unbiased estimation of the genomic relationship matrix in pigs 短通信: 基于猪基因组关系矩阵无偏估计的基因组预测

ANIMAL

IF4.2

2025-02-01

OAAI

Li, M. Y.; Shi, L. Y.; Machugh, D. E.; Wang, X. Q.; Tian, J. J.; Wang, L. G.; Deng, Y. J.; Wang, L. X.; Zhao, F. P.

Genome-wide local ancestry and the functional consequences of admixture in African and European cattle populations

HEREDITY

IF3.9

2024-11-08

PREAI

McHugo, Gillian P.; Ward, James A.; Ng'ang'a, Said Ismael; Frantz, Laurent A. F.; Salter-Townshend, Michael; Hill, Emmeline W.; O'Gorman, Grace M.; Meade, Kieran G.; Hall, Thomas J.; MacHugh, David E.

Recent selection and introgression facilitated high-altitude adaptation in cattle 最近的选择和渗入促进了牛的高海拔适应

SCIENCE BULLETIN

IF21.1

2024-11-01

PREAI

Lyu, Yang; Wang, Fuwen; Cheng, Haijian; Han, Jing; Dang, Ruihua; Xia, Xiaoting; Wang, Hui; Zhong, Jincheng; Lenstra, Johannes A.; Zhang, Hucai; Han, Jianlin; Machugh, David E.; Medugorac, Ivica; Upadhyay, Maulik; Leonard, Alexander S.; Ding, He; Yang, Xiaorui; Wang, Ming-Shan; Quji, Suolang; Zhuzha, Basang; Quzhen, Pubu; Wangmu, Silang; Cangjue, Nima; Wa, Da; Ma, Weidong; Liu, Jianyong; Zhang, Jicai; Huang, Bizhi; Qi, Xingshan; Li, Fuqiang; Huang, Yongzhen; Ma, Yun; Wang, Yu; Gao, Yuanpeng; Lu, Wenfa; Lei, Chuzhao; Chen, Ningbo

Preferential differential gene expression within the WC1.1+ γδ T cell compartment in cattle naturally infected with Mycobacterium bovis

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-10-24

OAAI

Bhat, Sajad A.; Elnaggar, Mahmoud; Hall, Thomas J.; McHugo, Gillian P.; Reid, Cian; MacHugh, David E.; Meade, Kieran G.

Transcriptome profiling of differentiating adipose-derived stem cells across species reveals new genes regulating adipogenesis

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

IF3.3

2023-10-01

PREAI

Han, Jiangang; Li, Xiaojie; Liang, Benmeng; Ma, Sijia; Pu, Yabin; Yu, Fuqing; Lu, Jian; Ma, Yuehui; Machugh, David E.; Jiang, Lin

Selection signatures for local and regional adaptation in Chinese Mongolian horse breeds reveal candidate genes for hoof health 中国蒙古马品种的局部和区域适应性选择特征揭示了蹄健康的候选基因

BMC GENOMICS

IF3.7

2023-01-19

OAAI

Han, Haige; Randhawa, Imtiaz A. S.; MacHugh, David E.; McGivney, Beatrice A.; Katz, Lisa M.; Dugarjaviin, Manglai; Hill, Emmeline W.

Common protein-coding variants influence the racing phenotype in galloping racehorse breeds 常见的蛋白质编码变体会影响奔腾的赛马品种的赛车表型

COMMUNICATIONS BIOLOGY

IF5.1

2022-12-13

OAAI

Han, Haige; McGivney, Beatrice A.; Allen, Lucy; Bai, Dongyi; Corduff, Leanne R.; Davaakhuu, Gantulga; Davaasambuu, Jargalsaikhan; Dorjgotov, Dulguun; Hall, Thomas J.; Hemmings, Andrew J.; Holtby, Amy R.; Jambal, Tuyatsetseg; Jargalsaikhan, Badarch; Jargalsaikhan, Uyasakh; Kadri, Naveen K.; MacHugh, David E.; Pausch, Hubert; Readhead, Carol; Warburton, David; Dugarjaviin, Manglai; Hill, Emmeline W.

Inbreeding depression and the probability of racing in the Thoroughbred horse 近亲繁殖的萧条和纯种马比赛的可能性

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF3.5

2022-06-29

OAAI

Hill, Emmeline W.; Stoffel, Martin A.; McGivney, Beatrice A.; MacHugh, David E.; Pemberton, Josephine M.

Timing of Transcriptomic Peripheral Blood Mononuclear Cell Responses of Sheep to Fasciola hepatica Infection Differs From Those of Cattle, Reflecting Different Disease Phenotypes

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-09-20

OAAI

Niedziela, Dagmara A.; Naranjo-Lucena, Amalia; Molina-Hernandez, Veronica; Browne, John A.; Martinez-Moreno, Alvaro; Perez, Jose; MacHugh, David E.; Mulcahy, Grace

Transcriptomic Analysis of Ovine Hepatic Lymph Node Following Fasciola hepatica Infection - Inhibition of NK Cell and IgE-Mediated Signaling

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-05-28

OAAI

Naranjo-Lucena, Amalia; Correia, Carolina N.; Molina-Hernandez, Veronica; Martinez-Moreno, Alvaro; Browne, John A.; Perez, Jose; MacHugh, David E.; Mulcahy, Grace

Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria

BMC GENOMICS

IF3.7

2021-05-12

OAAI

Hall, Thomas J.; Mullen, Michael P.; McHugo, Gillian P.; Killick, Kate E.; Ring, Siobhan C.; Berry, Donagh P.; Correia, Carolina N.; Browne, John A.; Gordon, Stephen, V; MacHugh, David E.

研究方向