Michele Tinti - Publications, H-index & Citations

Michele Tinti

university of dundee

23H指数

81论文数

2.3K被引数

收录论文 38

发表时间

Zinc-dependent turnover of ZIP3 transporter mRNA by trypanosome ZNK1 锌依赖的ZIP3转运蛋白mRNA由锥虫ZNK1介导的周转

Nucleic Acids Research

IF13.1

2026-09-12

OAAI

Teresa Leão; Anna Trenaman; Michele Tinti; Gustavo Bravo Ruiz; Idálio J Viegas; Luisa M Figueiredo; Margarida Duarte; Ana Maria Tomás; David Horn

Spliceosome induction is a druggable dependency of RAS-driven senescence and cancer 剪接体诱导是RAS驱动的衰老和癌症的药物依赖性

Nature Communications

IF15.7

2026-04-15

OAAI

Verena Wagner; Laura Bousset; Mariana Ascensão-Ferreira; Bin Sun; José Efren Barragan Avila; Alexandre Kaizeler; Rita Martins-Silva; Mohammad Rahbari; Mirian Fernández-Vaquero; Scott Haston; Michele Tinti; Joaquim Pombo; Sanjay Khadayate; Susanne Roth; Christian M. Schürch; Juan Pedro Martínez-Barbera; Anat Bahat; Keng Boon Wee; Jennifer P. Morton; Nisar Malek; Andrew J. Innes; Santiago Vernia; Nuno L. Barbosa-Morais; Suchira Gallage; Mathias Heikenwalder; Jesús Gil

A non-coding role for trypanosome VSG transcripts in allelic exclusion 锥虫VSG转录本在等位排斥中的非编码作用

NUCLEIC ACIDS RESEARCH

IF13.1

2025-10-28

PREAI

Escrivani, Douglas O.; Hutchinson, Sebastian; Tinti, Michele; Wright, Jane E.; Marques, Catarina A.; Faria, Joana R. C.; Trenaman, Anna; Horn, David

Cryptosporidium oocyst wall proteins are true components of the oocyst wall and COWP8 is not required for parasite transmission 隐孢子虫卵囊壁蛋白是卵囊壁的真实组成部分，而COWP8并非寄生虫传播所必需。

PLOS PATHOGENS

IF4.9

2025-10-01

PREAI

Bacchetti, Ross; Stevens, Sarah; Lemgruber, Leandro; Oliva, Mariana Azevedo Gonzalez; Sands, Emma M.; Alexandrou, Konstantinos; Tinti, Michele; Robinson, Lee; Hanna, Jack C.; Seizova, Simona; Goddard, Peyton; Vassalli, Massimo; Pawlowic, Mattie Christine

Antitrypanosomal quinazolines targeting lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease 抗锥虫噻唑啉酮类化合物靶向赖氨酰-tRNA合成酶，在急性恰加斯病小鼠模型中显示出部分疗效。

Science Translational Medicine

IF14.6

2025-07-09

PREAI

Lindsay B. Tulloch; Hugh Tawell; Annie E. Taylor; Marta Lopes Lima; Alice Dawson; Sandra Carvalho; Richard J. Wall; Victoriano Corpas-Lopez; Gourav Dey; Jack Duggan; Luma Godoy Magalhaes; Leah S. Torrie; Laura Frame; David Robinson; Stephen Patterson; Michele Tinti; George W. Weaver; William J. Robinson; Monica Cal; Marcel Kaiser; Pascal Mäser; Peter Sjö; Benjamin Perry; John M. Kelly; Amanda Fortes Francisco; Avninder S. Bhambra; Susan Wyllie

A high-throughput protein tagging toolkit that retains endogenous untranslated regions for studying gene regulation in kinetoplastids 一种保留内源非翻译区的高通量蛋白质标记工具包，用于研究动基体目生物的基因调控

OPEN BIOLOGY

IF3.6

2025-02-26

OAAI

Carbajo, Carla Gilabert; Han, Xiaoyang; Savur, Bhairavi; Upadhyaya, Arushi; Taha, Fatima; Tinti, Michele; Wheeler, Richard J.; Yates, Phillip A.; Tiengwe, Calvin

Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-10-23

PREAI

Caldwell, Nicola; Peet, Caroline; Miller, Peter; Colon, Beatrice L.; Taylor, Malcolm G.; Cocco, Mattia; Dawson, Alice; Lukac, Iva; Teixeira, Jose E.; Robinson, Lee; Frame, Laura; Seizova, Simona; Damerow, Sebastian; Tamaki, Fabio; Post, John; Riley, Jennifer; Mutter, Nicole; Hanna, Jack C.; Ferguson, Liam; Hu, Xiao; Tinti, Michele; Forte, Barbara; Norcross, Neil R.; Campbell, Peter S.; Svensen, Nina; Caldwell, Flora C.; Jansen, Chimed; Postis, Vincent; Read, Kevin D.; Huston, Christopher D.; Gilbert, Ian H.; Baragana, Beatriz; Pawlowic, Mattie C.

Post-transcriptional reprogramming by thousands of mRNA untranslated regions in trypanosomes

NATURE COMMUNICATIONS

IF15.7

2024-09-16

OAAI

Trenaman, Anna; Tinti, Michele; Wall, Richard J.; Horn, David

Sterol 14-alpha demethylase (CYP51) activity in Leishmania donovani is likely dependent upon cytochrome P450 reductase 1

PLOS PATHOGENS

IF4.9

2024-07-11

OAAI

Tulloch, Lindsay B.; Tinti, Michele; Wall, Richard J.; Weidt, Stefan K.; Corpas- Lopez, Victoriano; Dey, Gourav; Smith, Terry K.; Fairlamb, Alan H.; Barrett, Michael P.; Wyllie, Susan

Genome-wide screens connect HD82 loss-of-function to purine analog resistance in African trypanosomes

MSPHERE

IF3.1

2024-01-30

OAAI

Trenaman, Anna; Tinti, Michele; Atrih, Abdelmadjid; Horn, David

RES-Seq-a barcoded library of drug-resistant Leishmania donovani allowing rapid assessment of cross-resistance and relative fitness

MBIO

IF4.7

2023-12-19

OAAI

Tulloch, Lindsay B.; Carvalho, Sandra; Lima, Marta; Wall, Richard J.; Tinti, Michele; Pinto, Erika G.; MacLean, Lorna; Wyllie, Susan

An allele-selective inter-chromosomal protein bridge supports monogenic antigen expression in the African trypanosome

NATURE COMMUNICATIONS

IF15.7

2023-12-11

OAAI

Faria, Joana R. C.; Tinti, Michele; Marques, Catarina A.; Zoltner, Martin; Yoshikawa, Harunori; Field, Mark C.; Horn, David

Competition among variants is predictable and contributes to the antigenic variation dynamics of African trypanosomes

PLOS PATHOGENS

IF4.9

2023-07-17

OAAI

Escrivani, Douglas; Scheidt, Viktor; Tinti, Michele; Faria, Joana; Horn, David

Deep learning models for predicting RNA degradation via dual crowdsourcing

NATURE MACHINE INTELLIGENCE

IF23.9

2022-12-14

OAAI

Wayment-Steele, Hannah K.; Kladwang, Wipapat; Watkins, Andrew M.; Kim, Do Soon; Tunguz, Bojan; Reade, Walter; Demkin, Maggie; Romano, Jonathan; Wellington-Oguri, Roger; Nicol, John J.; Gao, Jiayang; Onodera, Kazuki; Fujikawa, Kazuki; Mao, Hanfei; Vandewiele, Gilles; Tinti, Michele; Steenwinckel, Bram; Ito, Takuya; Noumi, Taiga; He, Shujun; Ishi, Keiichiro; Lee, Youhan; Ozturk, Fatih; Chiu, King Yuen; Ozturk, Emin; Amer, Karim; Fares, Mohamed; Participants, Eterna; Das, Rhiju

Genome-scale RNA interference profiling of Trypanosoma brucei cell cycle progression defects

NATURE COMMUNICATIONS

IF15.7

2022-09-10

OAAI

Marques, Catarina A.; Ridgway, Melanie; Tinti, Michele; Cassidy, Andrew; Horn, David

Oligo targeting for profiling drug resistance mutations in the parasitic trypanosomatids

NUCLEIC ACIDS RESEARCH

IF13.1

2022-05-07

OAAI

Altmann, Simone; Rico, Eva; Carvalho, Sandra; Ridgway, Melanie; Trenaman, Anna; Donnelly, Hannah; Tinti, Michele; Wyllie, Susan; Horn, David

Control of Variant Surface Glycoprotein Expression by CFB2 in Trypanosoma brucei and Quantitative Proteomic Connections to Translation and Cytokinesis

MSPHERE

IF3.1

2022-04-27

OAAI

Bravo Ruiz, Gustavo; Tinti, Michele; Ridgway, Melanie; Horn, David

Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei 核苷酸糖的生物合成发生在循环和血液形式的布氏锥虫的糖基中

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2021-02-16

OAAI

Guther, Maria Lucia Sampaio; Prescott, Alan R.; Kuettel, Sabine; Tinti, Michele; Ferguson, Michael A. J.

Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani

ACS INFECTIOUS DISEASES

IF3.8

2018-11-01

OAAI

Corpas-Lopez, Victoriano; Moniz, Sonia; Thomas, Michael; Wall, Richard J.; Torrie, Leah S.; Zander-Dinse, Dorothea; Tinti, Michele; Brand, Stephen; Stojanovski, Laste; Manthri, Sujatha; Hallyburton, Irene; Zuccotto, Fabio; Wyatt, Paul G.; De Rycker, Manu; Horn, David; Ferguson, Michael A. J.; Clos, Joachim; Read, Kevin D.; Fairlamb, Alan H.; Gilbert, Ian H.; Wyllie, Susan

Development of Chemical Proteomics for the Folateome and Analysis of the Kinetoplastid Folateome

ACS INFECTIOUS DISEASES

IF3.8

2018-09-28

OAAI

Webster, Lauren A.; Thomas, Michael; Urbaniak, Michael; Wyllie, Susan; Ong, Han; Tinti, Michele; Fairlamb, Alan H.; Boesche, Markus; Ghidelli-Disse, Sonja; Drewes, Gerard; Gilbert, Ian H.

研究方向