Jürgen Wess - Publications, H-index & Citations

Jürgen Wess

National Institute of Diabetes and Digestive and Kidney Diseases

91H指数

424论文数

2.8W被引数

收录论文 222

发表时间

G proteins of the G12 family expressed by POMC neurons regulate key metabolic functions G12家族的G蛋白由POMC神经元表达，调节关键代谢功能

Science Advances

IF12.5

2025-07-11

OAAI

Dhanush Haspula; Zhenzhong Cui; Srinivas Pittala; Yinghong Cui; Huiyan Lu; Yan Xiong; Jian Jin; Oksana Gavrilova; Eunsang Hwang; Jason Ajwani; Bryan Portillo; Kevin W. Williams; Asuka Inoue; Jürgen Wess

Regulation of GLP-1 and Glucagon Receptor Function by β-Arrestins in Metabolically Important Cell Types β-Arrestins对代谢相关重要细胞类型中GLP-1和胰高血糖素受体功能的调节

BIOCHEMISTRY

IF3

2025-02-21

PREAI

Liu, Liu; Rashid, Misbah; Wess, Jurgen

G12/13-mediated signaling stimulates hepatic glucose production and has a major impact on whole body glucose homeostasis

NATURE COMMUNICATIONS

IF15.7

2024-11-19

OAAI

Pittala, Srinivas; Haspula, Dhanush; Cui, Yinghong; Yang, Won-Mo; Kim, Young-Bum; Davis, Roger J.; Wing, Allison; Rotman, Yaron; McGuinness, Owen P.; Inoue, Asuka; Wess, Jurgen

Author Correction: Intra-islet α-cell Gs signaling promotes glucagon release( vol 15, 5129, 2024)

NATURE COMMUNICATIONS

IF15.7

2024-07-29

OAAI

Liu, Liu; Ei, Kimberley; Dattaroy, Diptadip; Barella, Luiz F.; Cui, Yinghong; Gray, Sarah M.; Guedikian, Carla; Chen, Min; Weinstein, Lee S.; Knuth, Emily; Jin, Erli; Merrins, Matthew J.; Roman, Jeffrey; Kaestner, Klaus H.; Doliba, Nicolai; Campbell, Jonathan E.; Wess, Jurgen

Temporal Resolution of Single-Cell Transcriptomics and Epigenomics of Murine Pancreatic Islet in Diet-Induced Obesity

DIABETES

IF7.5

2024-06-14

PREAI

Singh, Simran; Musale, Krushna Pavan; Barella, Luiz F.; Shree, Ajita; Zafar, Hamim; Wess, Jurgen; Pydi, Sai Prasad

Receptor-Mediated G12 Signaling Strongly Promotes Insulin Secretion from Pancreatic Beta Cells

DIABETES

IF7.5

2024-06-14

PREAI

Pittala, Srinivas; Haspula, Dhanush; Liu, Liu; Cui, Yinghong; Wess, Jurgen

Hepatic GRK2 is dispensable for glucose homeostasis and other key metabolic parameters in mice

MOLECULAR METABOLISM

IF6.6

2024-01-01

OAAI

Oteng, Antwi-Boasiako; Pittala, Srinivas; Kliewer, Andrea; Qiu, Yishu; Wess, Juergen

An Intraislet Paracrine Signaling Pathway That Enables Glucagon to Stimulate Pancreatic β-Cells

DIABETES

IF7.5

2023-11-20

OAAI

Caicedo, Alejandro; Huising, Mark O.; Wess, Juergen

Intracellular signaling pathways of muscarinic acetylcholine receptor-mediated detrusor muscle contractions 毒蕈碱型乙酰胆碱受体介导逼尿肌收缩的细胞内信号通路

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY

IF3.4

2023-11-01

PREAI

Balla, Helga; Borsodi, Kinga; Orsy, Petra; Horvath, Bela; Molnar, Peter Jozsef; Lenart, Adam; Kosztelnik, Monika; Ruisanchez, Eva; Wess, Juergen; Offermanns, Stefan; Nyirady, Peter; Benyo, Zoltan

b-Arrestins: Structure, Function, Physiology, and Pharmacological Perspectives

PHARMACOLOGICAL REVIEWS

IF17.3

2023-09-01

OAAI

Wess, Jurgen; Oteng, Antwi-Boasiako; Rivera-Gonzalez, Osvaldo; V. Gurevich, Eugenia; V. Gurevich, Vsevolod

The third intracellular loop of GPCRs: size matters

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2023-08-01

PREAI

Wess, Jurgen

Long-Term-But Not Short-Term-Plasticity at the Mossy Fiber-CA3 Pyramidal Cell Synapse in Hippocampus Is Altered in M1/M3 Muscarinic Acetylcholine Receptor Double Knockout Mice 在M1/M3毒蕈碱型乙酰胆碱受体双敲除小鼠中，海马中苔藓Fiber-CA3锥体细胞突触的长期而非短期可塑性发生改变

CELLS

IF5.2

2023-07-19

OAAI

Zheng, Fang; Wess, Jurgen; Alzheimer, Christian

Adipocyte G Protein-Coupled Receptors as Potential Targets for Novel Antidiabetic Drugs

DIABETES

IF7.5

2023-06-20

PREAI

Liu, Liu; Wess, Jurgen

Gs-DREADD Knock-In Mice for Tissue-Specific, Temporal Stimulation of Cyclic AMP Signaling

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-17

OAAI

Akhmedov, Dmitry; Mendoza-Rodriguez, Maria G.; Rajendran, Kavitha; Rossi, Mario; Wess, Juergen; Berdeaux, Rebecca

Enhancer looping protein LDB1 regulates hepatocyte gene expression by cooperating with liver transcription factors

NUCLEIC ACIDS RESEARCH

IF13.1

2022-08-26

OAAI

Liu, Guoyou; Wang, Lei; Wess, Jurgen; Dean, Ann

Adipocyte Gq signaling is a regulator of glucose and lipid homeostasis in mice 脂肪细胞Gq信号是小鼠葡萄糖和脂质稳态的调节剂

NATURE COMMUNICATIONS

IF15.7

2022-03-29

OAAI

Kimura, Takefumi; Pydi, Sai P.; Wang, Lei; Haspula, Dhanush; Cui, Yinghong; Lu, Huiyan; Koenig, Gabriele M.; Kostenis, Evi; Steinberg, Gregory R.; Gavrilova, Oksana; Wess, Juergen

β-Arrestins as Important Regulators of Glucose and Energy Homeostasis

ANNUAL REVIEW OF PHYSIOLOGY

IF19.1

2022-02-10

OAAI

Pydi, Sai P.; Barella, Luiz E.; Zhu, Lu; Meister, Jaroslawna; Rossi, Mario; Wess, Jurgen

Clenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells 克伦特罗通过骨骼肌细胞的代谢重编程发挥抗糖尿病活性

NATURE COMMUNICATIONS

IF15.7

2022-01-10

OAAI

Meister, Jaroslawna; Bone, Derek B. J.; Knudsen, Jonas R.; Barella, Luiz F.; Velenosi, Thomas J.; Akhmedov, Dmitry; Lee, Regina J.; Cohen, Amanda H.; Gavrilova, Oksana; Cui, Yinghong; Karsenty, Gerard; Chen, Min; Weinstein, Lee S.; Kleinert, Maximilian; Berdeaux, Rebecca; Jensen, Thomas E.; Richter, Erik A.; Wess, Jurgen

In vivo metabolic effects after acute activation of skeletal muscle Gs signaling

MOLECULAR METABOLISM

IF6.6

2022-01-01

OAAI

Meister, Jaroslawna; Bone, Derek B. J.; Knudsen, Jonas R.; Barella, Luiz F.; Liu, Liu; Lee, Regina; Gavrilova, Oksana; Chen, Min; Weinstein, Lee S.; Kleinert, Maximilian; Jensen, Thomas E.; Wess, Juergen

Gq signaling in α cells is critical for q maintaining euglycemia

JCI INSIGHT

IF6.1

2021-12-22

OAAI

Liu, Liu; Dattaroy, Diptadip; Simpson, Katherine F.; Barella, Luiz F.; Cui, Yinghong; Xiong, Yan; Jin, Jian; Konig, Gabriele M.; Kostenis, Evi; Roman, Jefferey C.; Kaestner, Klaus H.; Doliba, Nicolai M.; Wess, Jurgen

研究方向