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L

Leslie Naesens

Ghent University
H指数:15
被引数:3,275

个人简介

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教育背景

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工作经历

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荣誉奖项

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A Novel Heterozygous Variant in AICDA Impairs Ig Class Switching and Somatic Hypermutation in Human B Cells and is Associated with Autosomal Dominant HIGM2 Syndrome

AICDA中的一种新的杂合变体会损害人b细胞中的Ig类别转换和体细胞超突变，并与常染色体显性HIGM2综合征相关

JOURNAL OF CLINICAL IMMUNOLOGY
IF5.7
2024-02-160
OAAI
Della Mina, Erika; Jackson, Katherine J. L.; Crawford, Alexander J. I.; Faulks, Megan L.; Pathmanandavel, Karrnan; Acquarola, Nicolino; O'Sullivan, Michael; Kerre, Tessa; Naesens, Leslie; Claes, Karlien; Goodnow, Christopher C.; Haerynck, Filomeen; Kracker, Sven; Meyts, Isabelle; D'Orsogna, Lloyd J.; Ma, Cindy S.; Tangye, Stuart G.
Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment
CELL REPORTS MEDICINE
IF10.6
2022-12-0123
OAAI
Bosteels, Cedric; Van Damme, Karel F. A.; De Leeuw, Elisabeth; Declercq, Jozefien; Maes, Bastiaan; Bosteels, Victor; Hoste, Levi; Naesens, Leslie; Debeuf, Nincy; Deckers, Julie; Cole, Basiel; Pardons, Marion; Weiskopf, Daniela; Sette, Alessandro; Vande Weygaerde, Yannick; Malfait, Thomas; Vandecasteele, Stefaan J.; Demedts, Ingel K.; Slabbynck, Hans; Allard, Sabine; Depuydt, Pieter; Van Braeckel, Eva; De Clercq, Jozefien; Martens, Liesbet; Dupont, Sam; Seurinck, Ruth; Vandamme, Niels; Haerynck, Filomeen; Roychowdhury, Debasish F.; Vandekerckhove, Linos; Guilliams, Martin; Tavernier, Simon J.; Lambrecht, Bart N.
GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the hostderived RIG-I ligand RNA5SP141

GTF3A突变通过破坏宿主衍生的rig-i配体RNA5SP141的生物发生而易患单纯疱疹病毒性脑炎

SCIENCE IMMUNOLOGY
IF16.3
2022-11-2518
OA
Naesens, Leslie; Muppala, Santoshi; Acharya, Dhiraj; Nemegeer, Josephine; Bogaert, Delfien; Lee, Jung-Hyun; Staes, Katrien; Debacker, Veronique; De Bruyne, Marieke; De Bleser, Pieter; De Baere, Elfride; van Gent, Michiel; Liu, GuanQun; Lambrecht, Bart N.; Staal, Jens; Kerre, Tessa; Beyaert, Rudi; Maelfait, Jonathan; Tavernier, Simon J.; Gack, Michaela U.; Haerynck, Filomeen
Shortcutting the diagnostic odyssey: the multidisciplinary Program for Undiagnosed Rare Diseases in adults (UD-PrOZA)
ORPHANET JOURNAL OF RARE DISEASES
IF3.5
2022-05-2320
OAAI
Schuermans, Nika; Hemelsoet, Dimitri; Terryn, Wim; Steyaert, Sanne; Van Coster, Rudy; Coucke, Paul J.; Steyaert, Wouter; Callewaert, Bert; Bogaert, Elke; Verloo, Patrick; Vanlander, Arnaud V.; Debackere, Elke; Ghijsels, Jody; LeBlanc, Pontus; Verdin, Hannah; Naesens, Leslie; Haerynck, Filomeen; Callens, Steven; Dermaut, Bart; Poppe, Bruce
Mutations in RNU7-1 Weaken Secondary RNA Structure, Induce MCP-1 and CXCL10 in CSF, and Result in Aicardi-Goutieres Syndrome with Severe End-Organ Involvement
JOURNAL OF CLINICAL IMMUNOLOGY
IF5.7
2022-03-2314
OAAI
Naesens, Leslie; Nemegeer, Josephine; Roelens, Filip; Vallaeys, Lore; Meuwissen, Marije; Janssens, Katrien; Verloo, Patrick; Ogunjimi, Benson; Hemelsoet, Dimitri; Hoste, Levi; Roels, Lisa; De Bruyne, Marieke; De Baere, Elfride; Van Dorpe, Jo; Dendooven, Amelie; Sieben, Anne; Rice, Gillian, I; Kerre, Tessa; Beyaert, Rudi; Uggenti, Carolina; Crow, Yanick J.; Tavernier, Simon J.; Maelfait, Jonathan; Haerynck, Filomeen
TIM3+TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2021-12-1654
OAAI
Hoste, Levi; Roels, Lisa; Naesens, Leslie; Bosteels, Victor; Vanhee, Stijn; Dupont, Sam; Bosteels, Cedric; Browaeys, Robin; Vandamme, Niels; Verstaen, Kevin; Roels, Jana; Van Damme, Karel F. A.; Maes, Bastiaan; De Leeuw, Elisabeth; Declercq, Jozefien; Aegerter, Helena; Seys, Leen; Smole, Ursula; De Prijck, Sofie; Vanheerswynghels, Manon; Claes, Karlien; Debacker, Veronique; Van Isterdael, Gert; Backers, Lynn; Claes, Kathleen B. M.; Bastard, Paul; Jouanguy, Emmanuelle; Zhang, Shen-Ying; Mets, Gilles; Dehoorne, Joke; Vandekerckhove, Kristof; Schelstraete, Petra; Willems, Jef; Willekens, Julie; Stordeur, Patrick; Janssens, Sophie; Beyaert, Rudi; Saeys, Yvan; Casanova, Jean-Laurent; Lambrecht, Bart N.; Haerynck, Filomeen; Tavernier, Simon J.
Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial
LANCET RESPIRATORY MEDICINE
IF32.8
2021-12-0195
OAAI
Declercq, Jozefien; Van Damme, Karel F. A.; De Leeuw, Elisabeth; Maes, Bastiaan; Bosteels, Cedric; Tavernier, Simon J.; De Buyser, Stefanie; Colman, Roos; Hites, Maya; Verschelden, Gil; Fivez, Tom; Moerman, Filip; Demedts, Ingel K.; Dauby, Nicolas; De Schryver, Nicolas; Govaerts, Elke; Vandecasteele, Stefaan J.; Van Laethem, Johan; Anguille, Sebastien; van Der Hilst, Jeroen; Misset, Benoit; Slabbynck, Hans; Wittebole, Xavier; Lienart, Fabienne; Legrand, Catherine; Buyse, Marc; Stevens, Dieter; Bauters, Fre; Seys, Leen J. M.; Aegerter, Helena; Smole, Ursula; Bosteels, Victor; Hoste, Levi; Naesens, Leslie; Haerynck, Filomeen; Vandekerckhove, Linos; Depuydt, Pieter; van Braeckel, Eva; Rottey, Sylvie; Peene, Isabelle; Van Der Straeten, Catherine; Hulstaert, Frank; Lambrecht, Bart N.
Case Report: Convalescent Plasma, a Targeted Therapy for Patients with CVID and Severe COVID-19
FRONTIERS IN IMMUNOLOGY
IF5.9
2020-11-2045
OAAI
Van Damme, Karel F. A.; Tavernier, Simon; Van Roy, Nele; De Leeuw, Elisabeth; Declercq, Jozefien; Bosteels, Cedric; Maes, Bastiaan; De Bruyne, Marieke; Bogaert, Delfien; Bosteels, Victor; Hoste, Levi; Naesens, Leslie; Maes, Piet; Grifoni, Alba; Weiskopf, Daniela; Sette, Alessandro; Depuydt, Pieter; Van Braeckel, Eva; Haerynck, Filomeen; Lambrecht, Bart N.
A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation (vol 10, 4779 , 2019)
NATURE COMMUNICATIONS
IF15.7
2019-11-201
OAAI
Tavernier, S. J.; Athanasopoulos, V.; Verloo, P.; Behrens, G.; Staal, J.; Bogaert, D. J.; Naesens, L.; De Bruyne, M.; Van Gassen, S.; Parthoens, E.; Ellyard, J.; Cappello, J.; Morris, L. X.; Van Gorp, H.; Van Isterdael, G.; Saeys, Y.; Lamkanfi, M.; Schelstraete, P.; Dehoorne, J.; Bordon, V.; Van Coster, R.; Lambrecht, B. N.; Menten, B.; Beyaert, R.; Vinuesa, C. G.; Heissmeyer, V.; Dullaers, M.; Haerynck, F.
A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation

人类免疫失调综合征，其特征是具有纯合无义Roquin-1突变的严重过度炎症

NATURE COMMUNICATIONS
IF15.7
2019-10-2142
OAAI
Tavernier, S. J.; Athanasopoulos, V.; Verloo, P.; Behrens, G.; Staal, J.; Bogaert, D. J.; Naesens, L.; De Bruyne, M.; Van Gassen, S.; Parthoens, E.; Ellyard, J.; Cappello, J.; Morris, L. X.; Van Gorp, H.; Van Isterdael, G.; Saeys, Y.; Lamkanfi, M.; Schelstraete, P.; Dehoorne, J.; Bordon, V.; Van Coster, R.; Lambrecht, B. N.; Menten, B.; Beyaert, R.; Vinuesa, C. G.; Heissmeyer, V.; Dullaers, M.; Haerynck, F.

研究方向

暂未获取到该数据
F
Filomeen Haerynck
H 指数:48论文数:258被引数:1.9万
L
Levi Hoste
H 指数:17论文数:61被引数:4,050
S
Simon J. Tavernier
H 指数:24论文数:88被引数:8,157
B
Bart N. Lambrecht
H 指数:123论文数:763被引数:6.3万
B
Beyaert, Rudi
H 指数:0论文数:1被引数:214
T
Tessa Kerre
H 指数:33论文数:281被引数:3,659
P
Petra Schelstraete
H 指数:25论文数:129被引数:3,073
V
Victor Bosteels
H 指数:12论文数:54被引数:915
C
Cédric Bosteels
H 指数:19论文数:58被引数:5,318
E
Elisabeth De Leeuw
H 指数:10论文数:24被引数:1,125