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Thomas Klose

pennsylvania commonwealth system of higher education (pcshe)

45H指数
170论文数
6.5K被引数
收录论文 66
发表时间
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Asymmetric structural transitions in the icosahedral organization of Eastern equine encephalitis virus东方马脑炎病毒二十面体结构中的非对称结构转换
errNature Communications
IF15.7
err2026-05-15
err0
errOAAI
errAbhishek Bandyopadhyay; Lauren E. Williamson; Cameron D. Buchman; Thomas Klose; James E. Crowe; Richard J. Kuhn
err分享
err收藏
Analysis of the heterogenous structural states of the hexameric ATPase PilU of the type IV pili from Vibrio cholerae解析霍乱弧菌四型菌毛六聚体ATP酶PilU的异质性结构状态
errProtein Science
IF5.2
err2026-05-05
err0
errOAAI
errYirui Guo; Shantanu Shukla; George Minasov; Nicole L. Inniss; Thomas Klose; Valerie L. Tokars; Alfonso Mondragón; Zbyszek Otwinowski; Dominika Borek; Karla J. F. Satchell
err分享
err收藏
An RNA-to-RNA Pipeline for Rapid Antiviral Antibody DevelopmentRNA到RNA管线用于快速抗病毒抗体开发
errMolecular Therapy
IF12
err2026-04-09
err0
PREAI
errEdgar A. Hodge; Jacob Archer; Jacqueline S. Anderson; Nikole L. Warner; Jacque Tremblay; Thomas Klose; Stephanie Park; Troy Hinkley; Amit P. Khandhar; Richard Kuhn; Charles Shoemaker; Jesse H. Erasmus
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In situ structures of the portal-neck-tail complex of bacteriophage T4 inform a viral genome positioning mechanism噬菌体T4的门-颈-尾复合物的原位结构为病毒基因组定位机制提供了信息
errNature Communications
IF15.7
err2026-02-20
err0
errOAAI
errAndrei Fokine; Jingen Zhu; Thomas Klose; Frank Vago; Charles-Adrien Arnaud; Zhiqing Wang; Baldeep Khare; Michael G. Rossmann; Zhenguo Chen; Lei Sun; Qianglin Fang; Richard J. Kuhn; Venigalla B. Rao
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Rational design and in vivo validation of capsid inhibitors for enterovirus D68D68肠道病毒衣壳抑制剂的理性设计与体内验证
errNature Communications
IF15.7
err2026-02-10
err0
errOAAI
errKan Li; Michael J. Rudy; Thomas Klose; Haozhou Tan; Xiangmeng Wu; Hiwot A. Demssie; Jacqueline S. Anderson; Prakash Jadhav; Qing-Yu Zhang; Penny Clarke; Richard J. Kuhn; Kenneth L. Tyler; Jun Wang
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Informed mutation of western equine encephalitis virus to heparan sulfate binding: Implications for rational design of alphavirus live attenuated vaccines基于肝素硫酸盐结合的西方马脑炎病毒定向突变：对 alphavirus 减毒活疫苗理性设计的启示
errPLoS Pathogens
IF4.9
err2026-02-06
err0
PREAI
errLukash, Tetyana; Poudyal, Shishir; Gilliland Jr, Theron C.; Klose, Thomas; Sun, Chengqun; Vasilatos, Shauna N.; Farren, Jessica L.; Lam, Long Kwan Metthew; Kuhn, Richard J.; Klimstra, William B.
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Structural elucidation of a unique binding mode by an intact alphavirus human IgG molecule to a quaternary epitope独特结合模式的结构阐明：完整阿尔法病毒人IgG分子与四级表位的结合
errNature Communications
IF15.7
err2025-08-19
err0
errOAAI
errAbhishek Bandyopadhyay; Lauren E. Williamson; Devika Sirohi; Kevin Bailey; Theron Gilliland; Thomas Klose; Geeta Buda; Andrew Trivette; Chengqun Sun; Justin G. Julander; William B. Klimstra; James E. Crowe; Richard J. Kuhn
err分享
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Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-04-08
err1
PREAI
errYen, Yu-Chen; Li, Yong; Chen, Chun-Liang; Klose, Thomas; Watts, Val J.; Dessauer, Carmen W.; Tesmer, John J. G.
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Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-04-02
err0
errOAAI
errChen, Chun-Liang; Syahirah, Ramizah; Ravala, Sandeep K.; Yen, Yu-Chen; Klose, Thomas; Deng, Qing; Tesmer, John J. G.
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Structure Determination of MO14 Enterovirus D68 Mutation
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errJohnson, Alejandra; Anderson, Jacqueline; Klose, Thomas; Kuhn, Richard; Wang, Jun
err分享
err收藏
Structure of Vibrio Phage XM1, a Simple Contractile DNA Injection Machine
errVIRUSES-BASEL
IF3.5
err2023-07-31
err12
errOAAI
errWang, Zhiqing; Fokine, Andrei; Guo, Xinwu; Jiang, Wen; Rossmann, Michael G.; Kuhn, Richard J.; Luo, Zhu-Hua; Klose, Thomas
err分享
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Structural and Mechanistic Basis for Gbetagamma-mediated Activation of Phosphoinositide 3-kinase-gamma
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-06-01
err0
errOAAI
errChen, Chun-Liang; Ravala, Sandeep; Yen, Yu-Chen; Klose, Thomas; Syahirah, Ramizah; Tesmer, John J. G.; Deng, Qing
err分享
err收藏
Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-03-24
err2
errOAAI
errWilliamson, Lauren E.; Bandyopadhyay, Abhishek; Bailey, Kevin; Sirohi, Devika; Klose, Thomas; Julander, Justin G.; Kuhn, Richard J.; Crowe, James E.
err分享
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prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-01-13
err4
errOAAI
errDowd, Kimberly A.; Sirohi, Devika; Speer, Scott D.; VanBlargan, Laura A.; Chen, Rita E.; Mukherjee, Swati; Whitener, Bradley M.; Govero, Jennifer; Aleshnick, Maya; Larman, Bridget; Sukupolvi-Petty, Soila; Sevvana, Madhumati; Miller, Andrew S.; Klose, Thomas; Zheng, Aihua; Koenig, Scott; Kielian, Margaret; Kubn, Richard J.; Diamond, Michael S.; Pierson, Theodore C.
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Near-atomic, non-icosahedrally averaged structure of giant virus Paramecium bursaria chlorella virus 1
errNATURE COMMUNICATIONS
IF15.7
err2022-10-29
err24
errOAAI
errShao, Qianqian; Agarkova, Irina, V; Noel, Eric A.; Dunigan, David D.; Liu, Yunshu; Wang, Aohan; Guo, Mingcheng; Xie, Linlin; Zhao, Xinyue; Rossmann, Michael G.; Van Etten, James L.; Klose, Thomas; Fang, Qianglin
err分享
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Cryo-EM structures of alphavirus conformational intermediates in low pH-triggered prefusion states低pH触发的融合前状态下甲病毒构象中间体的cryo-em结构
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-07-22
err6
errOAAI
errChen, Chun-Liang; Klose, Thomas; Sun, Chengqun; Kim, Arthur S.; Buda, Geeta; Rossmann, Michael G.; Diamond, Michael S.; Klimstra, William B.; Kuhn, Richard J.
err分享
err收藏
Plasticity within the barrel domain of BamA mediates a hybrid-barrel mechanism by BAM
errNATURE COMMUNICATIONS
IF15.7
err2021-12-08
err33
errOAAI
errWu, Runrun; Bakelar, Jeremy W.; Lundquist, Karl; Zhang, Zijian; Kuo, Katie M.; Ryoo, David; Pang, Yui Tik; Sun, Chen; White, Tommi; Klose, Thomas; Jiang, Wen; Gumbart, James C.; Noinaj, Nicholas
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Cryo-EM reveals local and global structural rearrangements in RYR mutants: Calcium Signaling and Excitation-Contraction in Cardiac, Skeletal and Smooth Muscle
errJOURNAL OF GENERAL PHYSIOLOGY
IF2.9
err2021-11-12
err1
errOAAI
errIyer, Kavita A.; Hu, Yifan; Klose, Thomas; Murayama, Takashi; Samso, Montserrat
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Structure of Usutu virus SAAR-1776 displays fusion loop asymmetry
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2021-08-20
err9
errOAAI
errKhare, Baldeep; Klose, Thomas; Fang, Qianglin; Rossmann, Michael G.; Kuhn, Richard J.
err分享
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Structure of the rhodopsin-rhodopsin kinase complex defines the rules of engagement between G protein-coupled receptors (GPCRs) and GPCR kinases
errFASEB JOURNAL
IF4.2
err2021-05-14
err1
errOAAI
errChen, Qiuyan; Plasencia, Manolo; Li, Zhuang; Mukherjee, Somnath; Patra, Dhableswar; Chen, Chun-Liang; Klose, Thomas; Yao, Xin-Qiu; Kossiakoff, Anthony; Chang, Leifu; Andrews, Philip; Tesmer, John
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研究方向

暂无研究方向
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