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M

María García-Alai

european molecular biology laboratory hamburg

25H指数
97论文数
2.8K被引数
收录论文 32
发表时间
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Global analysis of thermal and chemical denaturation using CheMelt: Thermodynamic dissection of highly thermostable de novo designed proteins利用CheMelt进行热和化学变性的全球分析：对高度热稳定从头设计蛋白质的热力学解析
errProtein Science
IF5.2
err2026-10-01
err0
errOAAI
errVili Lampinen; Osvaldo Burastero; Iara Plácido Guazzelli; Florian Vögele; Francisca Pinheiro; Jan S. Nowak; Maria M. Garcia Alai; Magnus Kjaergaard
err分享
err收藏
Clathrin adaptors drive phase separation in endocytosis and trafficking笼蛋白接头驱动内吞作用和转运过程中的相分离
errCommunications Biology
IF5.1
err2026-09-26
err0
errOAAI
errGeorge Draper-Barr; Janina Schiller; Katharina Veith; Stephan Niebling; David Ruiz-Carrillo; Ziqiang Huang; Christian Tischer; Roland Thuenauer; Lucas A. Defelipe; Maria García-Alai
err分享
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Publisher Correction: Design, structure-based optimization and antiviral evaluation of potent inhibitors for the macrodomain Mac1 of SARS-CoV-2出版者更正：SARS-CoV-2巨域Mac1的高效抑制剂的设计、基于结构的优化和抗病毒评价
errNature Communications
IF15.7
err2026-09-25
err0
errOAAI
errMaximilian Sandmann; Sahra Tajdar; Simon Sander; David Ruiz Carrillo; Benedikt Ganter; Celine Fischer; Marina Ocenas; Stefanie Etzold; Neele Pekarek; Julia Berger; Toni Luise Meister; Barbara Selisko; Bruno Canard; Joanna M. Watt; Ondřej Baszczyňski; Barry VL Potter; Maria Garcia Alai; Henning Tidow; Susanne Pfefferle; Chris Meier; Ralf Fliegert
err分享
err收藏
Publisher Correction: Design, structure-based optimization and antiviral evaluation of potent inhibitors for the macrodomain Mac1 of SARS-CoV-2出版商更正：SARS-CoV-2巨域Mac1的高效抑制剂的设计、结构导向优化及抗病毒评价
errNature Communications
IF15.7
err2026-09-15
err0
errOAAI
errMaximilian Sandmann; Sahra Tajdar; Simon Sander; David Ruiz Carrillo; Benedikt Ganter; Celine Fischer; Marina Ocenas; Stefanie Etzold; Neele Pekarek; Julia Berger; Toni Luise Meister; Barbara Selisko; Bruno Canard; Joanna M. Watt; Ondřej Baszczyňski; Barry VL Potter; Maria Garcia Alai; Tidow Henning; Pfefferle Susanne; Chris Meier; Ralf Fliegert
err分享
err收藏
Design, structure-based optimization and antiviral evaluation of potent inhibitors for the macrodomain Mac1 of SARS-CoV-2针对SARS-CoV-2巨域Mac1的强效抑制剂的设计、基于结构的优化及抗病毒评价
errNature Communications
IF15.7
err2026-07-27
err0
errOAAI
errMaximilian Sandmann; Sahra Tajdar; Simon Sander; David Ruiz Carrillo; Benedikt Ganter; Celine Fischer; Marina Ocenas; Stefanie Etzold; Neele Pekarek; Julia Berger; Toni Luise Meister; Barbara Selisko; Bruno Canard; Joanna M. Watt; Ondřej Baszczyňski; Barry VL Potter; Maria Garcia Alai; Tidow Henning; Pfefferle Susanne; Chris Meier; Ralf Fliegert
err分享
err收藏
A bottom-up approach to find lead compounds in expansive chemical spaces一种自下而上的方法，用于在广阔的化学空间中寻找先导化合物
errCommunications Chemistry
IF6.2
err2025-08-01
err0
errOAAI
errÁlvaro Serrano-Morrás; Andrea Bertran-Mostazo; Marina Miñarro-Lleonar; Arnau Comajuncosa-Creus; Adrià Cabello; Carme Labranya; Carmen Escudero; Tian V. Tian; Inna Khutorianska; Dmytro S. Radchenko; Yurii S. Moroz; Lucas Defelipe; David Ruiz-Carrillo; Maria Garcia-Alai; Robert Schmidt; Matthias Rarey; Patrick Aloy; Carles Galdeano; Jordi Juárez-Jiménez; Xavier Barril
err分享
err收藏
Sla2 is a core interaction hub for clathrin light chain and the Pan1/End3/Sla1 complexSla2是网格蛋白轻链（clathrin light chain）和Pan1/End3/Sla1复合物的核心互作中心。
errStructure
IF4.3
err2025-05-09
err0
errOAAI
errGeorge Draper-Barr; Lucas A. Defelipe; David Ruiz-Carrillo; Emil Gustavsson; Meytal Landau; Maria García-Alai
err分享
err收藏
The Supramolecular Architecture of Mitochondrial Complex I in the Rat Brain Is Altered by Alzheimer's-Like Cerebral Amyloidosis大鼠脑中线粒体复合物I的超分子结构被阿尔茨海默病样脑淀粉样变性所改变
errJOURNAL OF NEUROCHEMISTRY
IF4
err2025-02-13
err0
PREAI
errNovack, Gisela V.; Galeano, Pablo; Defelipe, Lucas A.; Campanelli, Lorenzo; Campuzano, Karen S.; Rotondaro, Cecilia; Castano, Eduardo M.; Do Carmo, Sonia; Cuello, A. Claudio; Garcia-Alai, Maria M.; Morelli, Laura
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Structural and biophysical characterization of the cytoplasmic domains of HprS kinase and its interactions with the cognate regulator HprR
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2025-02-01
err0
PREAI
errKoczurowska, Anna; Carrillo, David Ruiz; Alai, Maria Garcia; Zaklos-Szyda, Malgorzata; Bujacz, Grzegorz; Pietrzyk-Brzezinska, Agnieszka J.
err分享
err收藏
SARS-CoV-2 M pro oligomerization as a potential target for therapy(vol 267, 131392, 2024)
errINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
IF8.5
err2024-09-01
err0
PREAI
errLis, Kinga; Plewka, Jacek; Menezes, Filipe; Bielecka, Ewa; Chykunova, Yuliya; Pustelny, Katarzyna; Niebling, Stephan; Garcia, Angelica Struve; -Alai, Maria Garcia; Popowicz, Grzegorz M.; Nowak, Jakub S.; Czarna, Anna; Kantyka, Tomasz; Pyrc, Krzysztof
err分享
err收藏
SARS-CoV-2 Mpro oligomerization as a potential target for therapy
errINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
IF8.5
err2024-05-01
err2
errOAAI
errLis, Kinga; Plewka, Jacek; Menezes, Filipe; Bielecka, Ewa; Chykunova, Yuliya; Pustelny, Katarzyna; Niebling, Stephan; Garcia, Angelica Struve; Garcia-Alai, Maria; Popowicz, Grzegorz M.; Czarna, Anna; Kantyka, Tomasz; Pyrc, Krzysztof
err分享
err收藏
Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans
errMOLECULAR PSYCHIATRY
IF10.1
err2022-11-30
err6
errOAAI
errNia, Fatemeh Hassani; Woike, Daniel; Bento, Isabel; Niebling, Stephan; Tibbe, Debora; Schulz, Kristina; Hirnet, Daniela; Skiba, Matilda; Hoenck, Hans-Hinrich; Veith, Katharina; Guenther, Christian; Scholz, Tasja; Bierhals, Tatjana; Driemeyer, Joenna; Bend, Renee; Failla, Antonio Virgilio; Lohr, Christian; Alai, Maria Garcia; Kreienkamp, Hans-Juergen
err分享
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New insights into P2X7 receptor regulation: Ca2+-calmodulin and GDP bind to the soluble P2X7 ballast domain
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-10-01
err4
errOAAI
errSander, Simon; Mueller, Isabel; Garcia-Alai, Maria M.; Nicke, Annette; Tidow, Henning
err分享
err收藏
Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease
errCOMMUNICATIONS BIOLOGY
IF5.1
err2022-08-11
err29
errOAAI
errSrinivasan, Vasundara; Brognaro, Hevila; Prabhu, Prince R.; de Souza, Edmarcia Elisa; Guenther, Sebastian; Reinke, Patrick Y. A.; Lane, Thomas J.; Ginn, Helen; Han, Huijong; Ewert, Wiebke; Sprenger, Janina; Koua, Faisal H. M.; Falke, Sven; Werner, Nadine; Andaleeb, Hina; Ullah, Najeeb; Franca, Bruno Alves; Wang, Mengying; Barra, Angelica Luana C.; Perbandt, Markus; Schwinzer, Martin; Schmidt, Christina; Brings, Lea; Lorenzen, Kristina; Schubert, Robin; Guaragna Machado, Rafael Rahal; Candido, Erika Donizette; Leal Oliveira, Danielle Bruna; Durigon, Edison Luiz; Niebling, Stephan; Garcia, Angelica Struve; Yefanov, Oleksandr; Lieske, Julia; Gelisio, Luca; Domaracky, Martin; Middendorf, Philipp; Groessler, Michael; Trost, Fabian; Galchenkova, Marina; Mashhour, Aida Rahmani; Saouane, Sofiane; Hakanpaeae, Johanna; Wolf, Markus; Alai, Maria Garcia; Turk, Dusan; Pearson, Arwen R.; Chapman, Henry N.; Hinrichs, Winfried; Wrenger, Carsten; Meents, Alke; Betzel, Christian
err分享
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The Cryo-EM structures of two amphibian antimicrobial cross-β amyloid fibrils
errNATURE COMMUNICATIONS
IF15.7
err2022-07-27
err18
errOAAI
errBucker, Robert; Seuring, Carolin; Cazey, Cornelia; Veith, Katharina; Garcia-Alai, Maria; Gruenewald, Kay; Landau, Meytal
err分享
err收藏
Cosolvent Sites-Based Discovery of Mycobacterium Tuberculosis Protein Kinase G Inhibitors
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-06-23
err4
errOAAI
errBurastero, Osvaldo; Defelipe, Lucas A.; Gola, Gabriel; Tateosian, Nancy L.; Lopez, Elias D.; Martinena, Camila Belen; Arcon, Juan Pablo; Traian, Martin Dodes; Wetzler, Diana E.; Bento, Isabel; Barril, Xavier; Ramirez, Javier; Marti, Marcelo A.; Garcia-Alai, Maria M.; Turjanski, Adrian G.
err分享
err收藏
Biophysical Screening Pipeline for Cryo-EM Grid Preparation of Membrane Proteins用于cryo-em网格制备膜蛋白的生物物理筛选管道
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2022-06-23
err11
errOAAI
errNiebling, Stephan; Veith, Katharina; Vollmer, Benjamin; Lizarrondo, Javier; Burastero, Osvaldo; Schiller, Janina; Garcia, Angelica Struve; Lewe, Philipp; Seuring, Carolin; Witt, Susanne; Garcia-Alai, Maria
err分享
err收藏
Opening opportunities for Kd determination and screening of MHC peptide complexes
errCOMMUNICATIONS BIOLOGY
IF5.1
err2022-05-23
err6
errOAAI
errKopicki, Janine-Denise; Saikia, Ankur; Niebling, Stephan; Guenther, Christian; Anjanappa, Raghavendra; Garcia-Alai, Maria; Springer, Sebastian; Uetrecht, Charlotte
err分享
err收藏
Dissociation of β2m from MHC class I triggers formation of noncovalent transient heavy chain dimers
errJOURNAL OF CELL SCIENCE
IF3.6
err2022-05-13
err10
errOAAI
errDirscherl, Cindy; Loechte, Sara; Hein, Zeynep; Kopicki, Janine-Denise; Harders, Antonia Regina; Linden, Noemi; Karner, Andreas; Preiner, Johannes; Weghuber, Julian; Garcia-Alai, Maria; Uetrecht, Charlotte; Zacharias, Martin; Piehler, Jacob; Lanzerstorfer, Peter; Springer, Sebastian
err分享
err收藏
Hydrazones and Thiosemicarbazones Targeting Protein-Protein-Interactions of SARS-CoV-2 Papain-like Protease
errFRONTIERS IN CHEMISTRY
IF4.2
err2022-04-11
err12
errOAAI
errEwert, Wiebke; Guenther, Sebastian; Miglioli, Francesca; Falke, Sven; Reinke, Patrick Y. A.; Niebling, Stephan; Guenther, Christian; Han, Huijong; Srinivasan, Vasundara; Brognaro, Hevila; Lieske, Julia; Lorenzen, Kristina; Garcia-Alai, Maria M.; Betzel, Christian; Carcelli, Mauro; Hinrichs, Winfried; Rogolino, Dominga; Meents, Alke
err分享
err收藏

研究方向

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