Jay T. Groves - Publications, H-index & Citations

Jay T. Groves

University of California

69H指数

376论文数

1.6W被引数

收录论文 205

发表时间

Disordered protein LAT encodes relative levels of signaling pathways in T cell activation LAT无序蛋白编码T细胞活化中信号通路的相对水平

Science

IF45.8

2026-04-30

PREAI

Adam J. Rubin; Tyler T. Dao; Amelia V. Schueppert; Saehyun Choi; Jay T. Groves; Aviv Regev; Alex K. Shalek

Single-molecule biophysics in signaling: Functionality from stochastic effects 信号传导中的单分子生物物理学：功能源于随机效应

Current Opinion in Cell Biology

IF4.3

2025-11-08

OAAI

Jay T. Groves

Autophosphorylation of oncoprotein TEL-ABL in myeloid and lymphoid cells confers resistance to the allosteric ABL inhibitor asciminib 髓系和淋巴系细胞中癌蛋白TEL-ABL的自磷酸化赋予其对异位性ABL抑制剂的抗性asciminib

Science Signaling

IF6.6

2025-07-15

PREAI

Serena Muratcioglu; Christopher A. Eide; Chien-Lun Hung; Kent Gorday; Emily Sumpena; Wenqi Zuo; Jay T. Groves; Brian J. Druker; John Kuriyan

Bacterial XopR subverts RIN4 complex-mediated plant immunity via plasma membrane-associated percolation 细菌XopR通过质膜相关渗透作用破坏RIN4复合物介导的植物免疫。

Developmental Cell

IF8.7

2025-03-25

PREAI

Xinlu Zhu; Weibing Wang; Simou Sun; Choon-Peng Chng; Yi Xie; Kexin Zhu; Danxia He; Qiyu Liang; Zhiming Ma; Xi Wu; Xuanang Zheng; Weibo Gao; Ali Miserez; Caiji Gao; Jing Yu; Changjin Huang; Jay T. Groves; Yansong Miao

Direct imaging with multidimensional labelling and high-content analysis allows quantitative categorization and characterizations of individual small extracellular vesicles and nanoparticles (sEVPs)通过多维标记和高内涵分析进行直接成像，可以对单个小细胞外囊泡和纳米颗粒 (sevp) 进行定量分类和表征

JOURNAL OF EXTRACELLULAR VESICLES

IF14.5

2024-12-12

OAAI

Sun, Simou; Cox-Vazquez, Sarah J.; Cho, Nam-Joon; Bazan, Guillermo C.; Groves, Jay T.

Positive feedback in Ras activation by full-length SOS arises from autoinhibition release mechanism

BIOPHYSICAL JOURNAL

IF3.1

2024-10-01

OAAI

Ren, He; Lee, Albert A.; Lew, L. J. Nugent; Degrandchamp, Joseph B.; Groves, Jay T.

Differential roles of kinetic on- and off- rates in T- cell receptor signal integration revealed with a modified Fab'- DNA ligand 修饰的Fab'- DNA配体揭示了T细胞受体信号整合中动力学速率和速率的差异作用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-09-19

OAAI

Wilhelm, Kiera B.; Vissa, Anand; Groves, Jay T.

Bimodality in Ras signaling originates from processivity of the Ras activator SOS without deterministic bistability

SCIENCE ADVANCES

IF12.5

2024-06-21

OAAI

Lee, Albert A.; Kim, Neil H.; Alvarez, Steven; Ren, He; DeGrandchamp, Joseph B.; Lew, L. J. Nugent; Groves, Jay T.

Allosteric inhibition of the T cell receptor by a designed membrane ligand

ELIFE

IF0

2023-10-05

OAAI

Ye, Yujie; Morita, Shumpei; Chang, Justin J.; Buckley, Patrick M.; Wilhelm, Kiera B.; DiMaio, Daniel; Groves, Jay T.; Barrera, Francisco N.

Stimulation of the catalytic activity of the tyrosine kinase Btk by the adaptor protein Grb2 衔接蛋白Grb2刺激酪氨酸激酶Btk的催化活性

ELIFE

IF0

2023-04-26

OAAI

Nocka, Laura M.; Eisen, Timothy J.; Iavarone, Anthony T.; Groves, Jay T.; Kuriyan, John; Murphy, James M.

A Membrane-Associated Light-Harvesting Model is Enabled by Functionalized Assemblies of Gene-Doubled TMV Proteins 通过基因倍增的TMV蛋白的功能化组装实现了膜相关的光捕获模型

SMALL

IF12.1

2023-02-21

OAAI

Dai, Jing; Wilhelm, Kiera B.; Bischoff, Amanda J.; Pereira, Jose H.; Dedeo, Michel T.; Garcia-Almedina, Derek M.; Adams, Paul D.; Groves, Jay T.; Francis, Matthew B.

Discrete LAT condensates encode antigen information from single pMHC:TCR binding events

NATURE COMMUNICATIONS

IF15.7

2022-12-02

OAAI

McAffee, Darren B.; O'Dair, Mark K.; Lin, Jenny J.; Low-Nam, Shalini T.; Wilhelm, Kiera B.; Kim, Sungi; Morita, Shumpei; Groves, Jay T.

Kinetic frustration by limited bond availability controls the LAT protein condensation phase transition on membranes

SCIENCE ADVANCES

IF12.5

2022-11-04

OAAI

Sun, Simou; GrandPre, Trevor; Limmer, David T.; Groves, Jay T.

Membrane-mediated dimerization potentiates PIP5K lipid kinase activity 膜介导的二聚化增强PIP5K脂质激酶活性

ELIFE

IF0

2022-08-17

OAAI

Hansen, Scott D.; Lee, Albert A.; Duewell, Benjamin R.; Groves, Jay T.

A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane EGFR胞质尾和Grb2的两组分蛋白缩合物通过膜上的SOS调节Ras激活

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-05-04

OAAI

Lin, Chun-Wei; Nocka, Laura M.; Stinger, Brittany L.; DeGrandchamp, Joseph B.; Lew, L. J. Nugent; Alvarez, Steven; Phan, Henry T.; Kondo, Yasushi; Kuriyan, John; Groves, Jay T.

Competition for shared downstream signaling molecules establishes indirect negative feedback between EGFR and EphA2

BIOPHYSICAL JOURNAL

IF3.1

2022-05-01

OAAI

Oh, Dongmyung; Chen, Zhongwen; Biswas, Kabir H.; Bai, Funing; Ong, Hui Ting; Sheetz, Michael P.; Groves, Jay T.

Stochasticity and positive feedback enable enzyme kinetics at the membrane to sense reaction size

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-11-17

OAAI

Lee, Albert A.; Huang, William Y. C.; Hansen, Scott D.; Kim, Neil H.; Alvarez, Steven; Groves, Jay T.

Relating cellular signaling timescales to single-molecule kinetics: A first-passage time analysis of Ras activation by SOS

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-11-05

OAAI

Huang, William Y. C.; Alvarez, Steven; Kondo, Yasushi; Kuriyan, John; Groves, Jay T.

Height, but not binding epitope, affects the potency of synthetic TCR agonists (vol 120, pg 3869, 2021)

BIOPHYSICAL JOURNAL

IF3.1

2021-11-01

OAAI

Wilhelm, Kiera B.; Morita, Shumpei; McAffee, Darren B.; Kim, Sungi; O'Dair, Mark K.; Groves, Jay T.

Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems

COMMUNICATIONS BIOLOGY

IF5.1

2021-09-09

OAAI

Laursen, Tomas; Lam, Hiu Yue Monatrice; Sorensen, Kasper Kildegaard; Tian, Pengfei; Hansen, Cecilie Cetti; Groves, Jay T.; Jensen, Knud Jorgen; Christensen, Sune M.

研究方向