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J

James D. Phelan

national institutes of health
H指数:29
被引数:6,059

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荣誉奖项

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Axes of biological variation in diffuse large B cell lymphoma

弥漫大B细胞淋巴瘤的生物变异轴

Cancer Cell
IF44.5
2026-01-150
PRE
Boya Wang; George Wright; Julius C. Enssle; Xin Yu; James D. Phelan; Yandan Yang; Arthur Shaffer; Arvin E. Ruiz; Da Wei Huang; Zana Coulibaly; Michael Kelly; Bao Tran; Stefania Pittaluga; Mark Roschewski; Wyndham H. Wilson; Thomas Oellerich; Giorgio Inghirami; Louis M. Staudt
An Assessment of Kinase Selectivity; Enzyme Inhibition Kinetics and in Vitro Activity for Several Bruton Tyrosine Kinase (BTK) Inhibitors

对激酶选择性的评估；几种布鲁顿酪氨酸激酶（BTK）抑制剂的酶抑制动力学及体外活性

ACS Pharmacology & Translational Science
IF3.7
2025-11-180
OAAI
Ana Corrionero; Xiaohu Zhang; Patricia Alfonso; Patrick J. Morris; Carleen Klumpp-Thomas; Christopher Melani; Crystal McKnight; James D. Phelan; David Holland; Kelli Wilson; Scott B. Hoyt; Mark Roschewski; Peter J. Tonge; Wyndham Wilson; Michele Ceribelli; Louis M. Staudt; Craig J. Thomas
BLIMP1 negatively regulates IL-2 signaling in T cells

BLIMP1负向调控T细胞中的IL-2信号通路。

Science Advances
IF12.5
2025-07-180
OA
Suyasha Roy; Min Ren; Peng Li; Kairong Cui; Yaqiang Cao; Bryan Fisk; Tovah E. Markowitz; Neelam Redekar; Keiko Sakamoto; Keisuke Nagao; Jangsuk Oh; Rosanne Spolski; Wei Liao; Sigrid P. Dubois; Brian L. Kelsall; Keji Zhao; James D. Phelan; Warren J. Leonard
Phase lb/2 Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Lenalidomide (ViPOR) in Relapsed/Refractory and Treatment-Naive Mantle Cell Lymphoma: Preliminary Analysis of Safety, Efficacy, and Minimal Residual Disease

维奈克拉、依鲁替尼、泼尼松、奥滨尤妥珠单抗和来那度胺（ViPOR）在复发/难治性及初治套细胞淋巴瘤中的lb/2期研究：安全性、有效性和微小残留病初步分析

BLOOD
IF23.1
2024-11-050
PRE
Melani, Christopher; Lakhotia, Rahul; Pittaluga, Stefania; Phelan, James D.; Muppidi, Jagan R.; Gordon, Max J.; Yang, Yandan; Xu, Weihong; Davies-Hill, Theresa; Huang, Da Wei; Thomas, Craig J.; Ceribelli, Michele; Tosto, Frances A.; Juanitez, Anna M.; Pradhan, Amynah; Morrison, Candis; Tadese, Atekelt; Ramsower, Colleen; Rimsza, Lisa M.; Jacob, Allison P.; Simmons, Heidi; Steinberg, Seth M.; Jaffe, Elaine S.; Roschewski, Mark; Staudt, Louis M.; Wilson, Wyndham H.
Gα13 restricts nutrient driven proliferation in mucosal germinal centers
NATURE IMMUNOLOGY
IF27.6
2024-07-180
OAAI
Nguyen, Hang T.; Li, Moyi; Vadakath, Rahul; Henke, Keirstin A.; Tran, Tam C.; Li, Huifang; Yamadi, Maryam; Darbha, Sriranjani; Yang, Yandan; Kabat, Juraj; Albright, Anne R.; Centeno, Enoc Granados; Phelan, James D.; Roulland, Sandrine; Huang, Da Wei; Kelly, Michael C.; Young, Ryan M.; Pittaluga, Stefania; Difilippantonio, Simone; Muppidi, Jagan R.
Combination Targeted Therapy in Relapsed Diffuse Large B-Cell Lymphoma
NEW ENGLAND JOURNAL OF MEDICINE
IF78.5
2024-06-205
OAAI
Melani, Christopher; Lakhotia, Rahul; Pittaluga, Stefania; Phelan, James D.; Huang, Da Wei; Wright, George; Simard, Jillian; Muppidi, Jagan; Thomas, Craig J.; Ceribelli, Michele; Tosto, Frances A.; Yang, Yandan; Xu, Weihong; Davies-Hill, Theresa; Pack, Svetlana D.; Peer, Cody J.; Arisa, Oluwatobi; Mena, Esther; Lindenberg, Liza; Bergvall, Ethan; Portell, Craig A.; Farah, Rafic J.; Lee, Seung Tae; Pradhan, Amynah; Morrison, Candis; Tadese, Atekelt; Juanitez, Anna Marie; Lu, Crystal; Jacob, Allison; Simmons, Heidi; Figg, William D.; Steinberg, Seth M.; Jaffe, Elaine S.; Roschewski, Mark; Staudt, Louis M.; Wilson, Wyndham H.
Molecular Determinants of Sensitivity to Polatuzumab Vedotin in Diffuse Large B-Cell Lymphoma
CANCER DISCOVERY
IF33.3
2024-04-251
OA
Corcoran, Sean R.; Phelan, James D.; Choi, Jaewoo; Shevchenko, Galina; Fenner, Rachel E.; Yu, Xin; Scheich, Sebastian; Hsiao, Tony; Morris, Vivian M.; Papachristou, Evangelia K.; Kishore, Kamal; D'Santos, Clive S.; Ji, Yanlong; Pittaluga, Stefania; Wright, George W.; Urlaub, Henning; Pan, Kuan-Ting; Oellerich, Thomas; Muppidi, Jagan; Hodson, Daniel J.; Staudt, Louis M.
Molecular mechanism of action and targets of glucocorticoids in lymphoma therapy
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Choi, Jaewoo; Ceribelli, Michele; Phelan, James D.; Haupl, Bjorn; Huang, Da Wei; Wright, George W.; Hsiao, Tony; Morris, Vivian; Ciccarese, Francesco; Wang, Boya; Corcoran, Sean; Scheich, Sebastian; Yu, Xin; Xu, Weihong; Yang, Yandan; Zhao, Hong; Zhou, Joyce; Zhang, Grace; Muppidi, Jagan; Inghirami, Giorgio Ga; Oellerich, Thomas; Thomas, Craig J.; Wilson, Wyndham H.; Staudt, Louis M.
Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
CANCER DISCOVERY
IF33.3
2023-05-0412
OA
Scheich, Sebastian; Chen, Jiji; Liu, Jiamin; Schnutgen, Frank; Enssle, Julius C.; Ceribelli, Michele; Thomas, Craig J.; Choi, Jaewoo; Morris, Vivian; Hsiao, Tony; Nguyen, Hang; Wang, Boya; Bolomsky, Arnold; Phelan, James D.; Corcoran, Sean; Urlaub, Henning; Young, Ryan M.; Haupl, Bjorn; Wright, George W.; Huang, Da Wei; Ji, Yanlong; Yu, Xin; Xu, Weihong; Yang, Yandan; Zhao, Hong; Muppidi, Jagan; Pan, Kuan-Ting; Oellerich, Thomas; Staudt, Louis M.
Oncogenic RAS commandeers amino acid sensing machinery to aberrantly activate mTORC1 in multiple myeloma (vol 13, 5469, 2022)
NATURE COMMUNICATIONS
IF15.7
2022-10-030
OAAI
Yang, Yandan; Bolomsky, Arnold; Oellerich, Thomas; Chen, Ping; Ceribelli, Michele; Haupl, Bjorn; Wright, George W.; Phelan, James D.; Huang, Da Wei; Lord, James W.; Van Winkle, Callie K.; Yu, Xin; Wisniewski, Jan; Wang, James Q.; Tosto, Frances A.; Beck, Erin; Wilson, Kelli; McKnight, Crystal; Travers, Jameson; Klumpp-Thomas, Carleen; Smith, Grace A.; Pittaluga, Stefania; Maric, Irina; Kazandjian, Dickran; Thomas, Craig J.; Young, Ryan M.
Oncogenic RAS commandeers amino acid sensing machinery to aberrantly activate mTORC1 in multiple myeloma
NATURE COMMUNICATIONS
IF15.7
2022-09-1710
OAAI
Yang, Yandan; Bolomsky, Arnold; Oellerich, Thomas; Chen, Ping; Ceribelli, Michele; Haupl, Bjorn; Wright, George W.; Phelan, James D.; Huang, Da Wei; Lord, James W.; Van Winkle, Callie K.; Yu, Xin; Wisniewski, Jan; Wang, James Q.; Tosto, Frances A.; Beck, Erin; Wilson, Kelli; McKnight, Crystal; Travers, Jameson; Klumpp-Thomas, Carleen; Smith, Grace A.; Pittaluga, Stefania; Maric, Irina; Kazandjian, Dickran; Thomas, Craig J.; Young, Ryan M.
A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1-mediated adhesion in T cells

靶向PI3K效应物的CRISPR筛选将RASA3鉴定为T细胞中LFA-1-mediated粘附的负调节因子

SCIENCE SIGNALING
IF6.6
2022-07-1916
OA
Johansen, Kristoffer H.; Golec, Dominic P.; Huang, Bonnie; Park, Chung; Thomsen, Julie H.; Preite, Silvia; Cannons, Jennifer L.; Garcon, Fabien; Schrom, Edward C.; Courreges, Christina J. F.; Veres, Tibor Z.; Harrison, James; Nus, Meritxell; Phelan, James D.; Bergmeier, Wolfgang; Kehrl, John H.; Okkenhaug, Klaus; Schwartzberg, Pamela L.
Overcoming Acquired Epigenetic Resistance to BTK Inhibitors
BLOOD CANCER DISCOVERY
IF11.5
2021-09-1437
OA
Shaffer, Arthur L., III; Phelan, James D.; Wang, James Q.; Huang, DaWei; Wright, George W.; Kasbekar, Monica; Choi, Jaewoo; Young, Ryan M.; Webster, Daniel E.; Yang, Yandan; Zhao, Hong; Yu, Xin; Xu, Weihong; Roulland, Sandrine; Ceribelli, Michele; Zhang, Xiaohu; Wilson, Kelli M.; Chen, Lu; McKnight, Crystal; Klumpp-Thomas, Carleen; Thomas, Craig J.; Haupl, Bjoern; Oellerich, Thomas; Rae, Zachary; Kelly, Michael C.; Ahn, Inhye E.; Sun, Clare; Gaglione, Erika M.; Wilson, Wyndham H.; Wiestner, Adrian; Staudt, Louis M.
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas
IMMUNITY
IF26.3
2021-01-0192
OAAI
Dersh, Devin; Phelan, James D.; Gumina, Megan E.; Wang, Boya; Arbuckle, Jesse H.; Holly, Jaroslav; Kishton, Rigel J.; Markowitz, Tovah E.; Seedhom, Mina O.; Fridlyand, Nathan; Wright, George W.; Huang, Da Wei; Ceribelli, Michele; Thomas, Craig J.; Lack, Justin B.; Restifo, Nicholas P.; Kristie, Thomas M.; Staudt, Louis M.; Yewdell, Jonathan W.

研究方向

暂未获取到该数据
L
Louis M. Staudt
H 指数:145论文数:802被引数:9.7万
G
George W. Wright
H 指数:71论文数:346被引数:3.7万
D
Da Wei Huang
H 指数:36论文数:158被引数:6.3万
Y
Yandan Yang
H 指数:35论文数:188被引数:1.2万
R
Ryan M. Young
H 指数:28论文数:103被引数:1.2万
S
Stefania Pittaluga
H 指数:116论文数:785被引数:4.5万
C
Craig J. Thomas
H 指数:79论文数:993被引数:2.8万
M
Michele Ceribelli
H 指数:33论文数:345被引数:5,611
T
Thomas Oellerich
H 指数:44论文数:343被引数:5,837
J
Jagan Muppidi
H 指数:22论文数:139被引数:2,263