Philip H. Howe - Publications, H-index & Citations

Philip H. Howe

medical university of south carolina

50H指数

153论文数

6.4K被引数

收录论文 62

发表时间

PCBP1 binding to single-stranded poly-cytosine motifs enhances cGAS sensing and impairs breast cancer development PCBP1与单链多聚胞嘧啶基序的结合增强了cGAS传感并抑制了乳腺癌发展

Communications Biology

IF5.1

2026-01-07

OAAI

Cécile Fréreux; Joseph A. Q. Karam; Breege V. Howley; Bryan Granger; Paramita Chakraborty; Silvia Vaena; Martin Romeo; Annamarie C. Dalton; Bidyut K. Mohanty; Shikhar Mehrotra; Philip H. Howe

The RNA-binding protein PCBP1 modulates transcription by recruiting the G-quadruplex-specific helicase DHX9

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-11-01

OAAI

Karam, Joseph A. Q.; Frereux, Cecile; Mohanty, Bidyut K.; Dalton, Annamarie C.; Dincman, Toros A.; Palanisamy, Viswanathan; V. Howley, Breege; Howe, Philip H.

Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response

CELL REPORTS

IF6.9

2024-08-01

OAAI

Wofford, Wyatt; Kim, Jisun; Kim, Dosung; Janneh, Alhaji H.; Lee, Han Gyul; Atilgan, Cansu; Oleinik, Natalia; Kassir, Mohamed Faisal; Saatci, Ozge; Chakraborty, Paramita; Tokat, Unal Metin; Gencer, Salih; Howley, Breege; Howe, Philip; Mehrotra, Shikhar; Sahin, Ozgur; Ogretmen, Besim

PRMT5-mediated arginine methylation of FXR1 is essential for RNA binding in cancer cells

NUCLEIC ACIDS RESEARCH

IF13.1

2024-05-06

OAAI

Vijayakumar, Anitha; Majumder, Mrinmoyee; Yin, Shasha; Brobbey, Charles; Karam, Joseph; Howley, Breege; Howe, Philip H.; Berto, Stefano; Madan, Lalima K.; Gan, Wenjian; Palanisamy, Viswanathan

Characterizing the role of PCBP1 in the activation of the cGAS-STING/type I Interferon axis to promote anti-tumor immunity

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Frereux, Cecile; Chakraborty, Paramita; Dalton, Annamarie C.; Howley, Breege V.; Granger, Bryan; Karam, Joseph A.; Vaena, Silvia G.; Romeo, Martin J.; Howe, Philip H.

Genomic amplifications identified by circulating tumor DNA analysis guide prognosis in metastatic castration-resistant prostate cancer

FRONTIERS IN ONCOLOGY

IF3.3

2024-02-21

OAAI

Dincman, Toros A.; Karam, Joseph A. Q.; Giordano, Antonio; Li, Hong; Drusbosky, Leylah M.; Gourdin, Theodore S.; Howe, Philip H.; Lilly, Michael B.

PCBP1 regulates LIFR through FAM3C to maintain breast cancer stem cell self-renewal and invasiveness

CANCER BIOLOGY & THERAPY

IF4.6

2023-11-06

OAAI

Streitfeld, William S.; Dalton, Annamarie C.; Howley, Breege V.; Howe, Philip H.

Autophagy dictates sensitivity to PRMT5 inhibitor in breast cancer

SCIENTIFIC REPORTS

IF3.9

2023-07-03

OAAI

Brobbey, Charles; Yin, Shasha; Liu, Liu; Ball, Lauren E.; Howe, Philip H.; Delaney, Joe R.; Gan, Wenjian

HOXA9 participates in the transcriptional activation of E-selectin in endothelial cells

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Bandyopadhyay, Smarajit; Ashraf, Mohammad Z.; Daher, Pamela; Howe, Philip H.; DiCorleto, Paul E.

A046: Heterogenous nuclear ribonucleoprotein E1 regulates leukemia inhibitory factor receptor (LIFR) expression through FAM3C in mammary epithelial cells

CANCER RESEARCH

IF16.6

2023-01-15

PREAI

Streitfeld, William S.; Dalton, Annamarie C.; Howe, Philip H.

Staphylococcus aureus peptidoglycan (PGN) induces pathogenic autoantibody production via autoreactive B cell receptor clonal selection, implications in systemic lupus erythematosus

JOURNAL OF AUTOIMMUNITY

IF7

2022-07-01

OAAI

Ning, Wangbin; Cheng, Da; Howe, Philip H.; Bian, Chuanxiu; Kamen, Diane L.; Luo, Zhenwu; Fu, Xiaoyu; Ogunrinde, Elizabeth; Yang, Liuqing; Wang, Xu; Li, Quan-Zhen; Oates, Jim; Zhang, Weiru; White, David; Wan, Zhuang; Gilkeson, Gary S.; Jiang, Wei

Direct NP- A cost-effective extraction-free RT-qPCR based test for SARS-CoV-2

HELIYON

IF3.6

2022-06-01

OAAI

Parikh, Rasesh Y.; Nadig, Satish N.; Mehrotra, Shikhar; Howe, Philip H.; Gangaraju, Vamsi K.

The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression

ONCOGENE

IF7.3

2022-01-31

OAAI

Howley, Breege, V; Mohanty, Bidyut; Dalton, Annamarie; Grelet, Simon; Karam, Joseph; Dincman, Toros; Howe, Philip H.

TGFβ-induced expression of long noncoding lincRNA Platr18 controls breast cancer axonogenesis

LIFE SCIENCE ALLIANCE

IF2.9

2021-11-22

OAAI

Grelet, Simon; Frereux, Cecile; Obellianne, Clemence; Noguchi, Ken; Howley, Breege, V; Dalton, Annamarie C.; Howe, Philip H.

Heterogeneous nuclear ribonucleoprotein E1 binds polycytosine DNA and monitors genome integrity

LIFE SCIENCE ALLIANCE

IF2.9

2021-07-16

OAAI

Mohanty, Bidyut K.; Karam, Joseph A. Q.; Howley, Breege, V; Dalton, Annamarie C.; Grelet, Simon; Dincman, Toros; Streitfeld, William S.; Yoon, Je-Hyun; Balakrishnan, Lata; Chazin, Walter J.; Long, David T.; Howe, Philip H.

RNA binding protein PCBP1 is an intracellular immune checkpoint for shaping T cell responses in cancer immunity

SCIENCE ADVANCES

IF12.5

2020-05-29

OAAI

Ansa-Addo, Ephraim A.; Huang, Huai-Cheng; Riesenberg, Brian; Iamaswat, Supinya; Borucki, Davis; Nelson, Michelle H.; Nam, Jin Hyun; Chung, Dongjun; Paulos, Chrystal M.; Liu, Bei; Yu, Xue-Zhong; Philpott, Caroline; Howe, Philip H.; Li, Zihai

TGF-beta signaling in cancer: post-transcriptional regulation of EMT via hnRNP E1

CYTOKINE

IF3.7

2019-06-01

OAAI

Howley, Breege V.; Howe, Philip H.

TGFβ promotes breast cancer stem cell self-renewal through an ILEI/LIFR signaling axis

ONCOGENE

IF7.3

2019-01-28

OAAI

Woosley, Alec N.; Dalton, Annamarie C.; Hussey, George S.; Howley, Breege V.; Mohanty, Bidyut K.; Grelet, Simon; Dincman, Toros; Bloos, Sean; Olsen, Shaun K.; Howe, Philip H.

Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-07-01

OAAI

Noguchi, Ken; Dincman, Toros A.; Dalton, Annamarie C.; Howley, Breege V.; McCall, Buckley J.; Mohanty, Bidyut K.; Howe, Philip H.

The Long (lncRNA) and Short (miRNA) of It: TGFβ-Mediated Control of RNA-Binding Proteins and Noncoding RNAs

MOLECULAR CANCER RESEARCH

IF4.7

2018-04-01

OAAI

Janakiraman, Harinarayanan; House, Reniqua P.; Gangaraju, Vamsi K.; Diehl, J. Alan; Howe, Philip H.; Palanisamy, Viswanathan

研究方向