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H

Hyun‐Shik Lee

Kyungpook National University

34H指数
211论文数
4.1K被引数
收录论文 76
发表时间
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Cathepsin L deletion enhances sensitivity to anticancer drugs through Parkin-mediated ubiquitination of Bcl-xL and USP53-induced Survivin destabilization通过Parkin介导的Bcl-xL泛素化和USP53诱导的Survivin失稳，Cathepsin L缺失增强了对抗癌药物的敏感性
errcell death & differentiation
IF0
err2026-06-15
err0
errOAAI
errSeung Un Seo; Seon Min Woo; Yongsoo Kwon; Shin Kim; Hyun-Shik Lee; Sang Hyun Kim; Kyoung-jin Min; Simmyung Yook; Taeg Kyu Kwon
err分享
err收藏
ROS–SUMO Crosstalk in Oxidative Stress: Disease Mechanisms and Reproductive HealthROS–SUMO串扰在氧化应激中的作用：疾病机制与生殖健康
errAntioxidants
IF6.6
err2026-04-04
err0
errOAAI
errAnn-Yae Na; Hyun-Shik Lee; Hong-Yeoul Ryu
err分享
err收藏
Symmetric Dimeric Structure and Ligand Recognition of CutR, a LysR-Type Transcriptional Regulator from Mycobacterium sp. Strain JC1CutR的对称二聚体结构与配体识别，CutR是一种来自Mycobacterium sp. Strain JC1的LysR型转录调控因子
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2025-10-29
err0
errOAAI
errCho, Hyo Je; Lee, Ka Young; Lee, Hyun-Shik; Kang, Beom Sik
err分享
err收藏
Down-regulation of HSPA9 reduces tyrosine hydroxylase-positive neurons in mouse substantia nigra and induces Parkinson’s disease-like motor impairmentsHSPA9的下调减少了小鼠黑质中酪氨酸羟化酶阳性神经元，并诱导帕金森病样运动障碍
errAnimal Cells and Systems
IF3.2
err2025-10-14
err0
errOAAI
errHyejin Hyung; Soyoung Jang; Si-Yong Kim; Ji-Eun Bae; Ji Yeong Park; Su-Geun Lim; Jiwon Ko; Soyeon Jang; Joon Bum Kim; Hee Young Chae; Song Park; Junkoo Yi; Dong Kyu Choi; Myoung Ok Kim; Hyun-Shik Lee; Dong-Hyung Cho; Zae Young Ryoo
err分享
err收藏
Mtx2 requirement for craniofacial morphogenesis with implications for mandibuloacral dysplasiaMtx2 对颅面形态发生的作用及其对颏-肢发育不良的启示
errBiochemical and Biophysical Research Communications
IF2.2
err2025-09-15
err0
PREAI
errBaeyoung Yang; Hyun-Kyung Lee; Hongchan Lee; Hong-Yeoul Ryu; Hyun Tae Kim; Hyun-Shik Lee
err分享
err收藏
Structural comparison of three MoaE proteins in Mycobacterium tuberculosis: Insights into molybdopterin synthase assembly and specificity分枝杆菌中三种MoaE蛋白的结构比较：对钼蝶呤合成酶组装和特异性的见解
errBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
IF2.2
err2025-07-01
err0
PREAI
errCho, Hyo Je; Yang, Seung Hyeon; Lee, Hyun-Shik; Kang, Beom Sik
err分享
err收藏
Auto-sumoylation of the yeast Ubc9 E2 SUMO-conjugating enzyme extends cellular lifespan酵母Ubc9 E2 SUMO连接酶的自身SUMO化延长细胞寿命
errNATURE COMMUNICATIONS
IF15.7
err2025-04-20
err0
errOAAI
errJeong, Dong-Won; Lee, Do Yoon; Kim, Seung Yeon; Jeoung, Seok-Won; Zhao, Dejian; Knight, James; Lam, TuKiet T.; Jin, Jong Hwa; Lee, Hyun-Shik; Ryu, Hong-Yeoul
err分享
err收藏
HSD17B4 deficiency causes dysregulation of primary cilia and is alleviated by acetyl-CoAHSD17B4缺乏导致主鞭毛失调，并被乙酰辅酶A缓解
errNATURE COMMUNICATIONS
IF15.7
err2025-03-18
err0
errOAAI
errBae, Ji-Eun; Jang, Soyoung; Kim, Joon Bum; Park, Na Yeon; Jo, Doo Sin; Hyung, Hyejin; Kim, Pansoo; Kim, Min-Seon; Ryu, Hong-Yeoul; Lee, Hyun-Shik; Lee, Dong-Seok; Baes, Myriam; Ryoo, Zae Young
err分享
err收藏
Non-canonical deubiquitination of OTUB1 induces IFNγ-mediated cell cycle arrest via regulation of p27 stability
errONCOGENE
IF7.3
err2024-04-25
err1
errOAAI
errLee, Seul Gi; Woo, Seon Min; Seo, Seung Un; Lee, Hyun Shik; Kim, Sang Hyun; Chang, Young-Chae; Cho, Hyo Je; Yook, Simmyung; Nam, Ju-Ock; Kwon, Taeg Kyu
err分享
err收藏
Enhanced primary ciliogenesis via mitochondrial oxidative stress activates AKT to prevent neurotoxicity in HSPA9/mortalin-depleted SH-SY5Y cells
errMOLECULAR BRAIN
IF2.9
err2023-05-11
err4
errOAAI
errBae, Ji-Eun; Jang, Soyoung; Kim, Joon Bum; Hyung, Hyejin; Park, Na Yeon; Kim, Yong Hwan; Kim, So Hyun; Kim, Seong Hyun; Ha, Jin Min; Oh, Gyeong Seok; Park, Kyuhee; Jeong, Kwiwan; Jang, Jae Seon; Jo, Doo Sin; Kim, Pansoo; Lee, Hyun-Shik; Ryoo, Zae Young; Cho, Dong-Hyung
err分享
err收藏
A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development
errSCIENCE ADVANCES
IF12.5
err2023-04-07
err4
errOAAI
errLee, Julie; Moller, Andreas Fonss; Chae, Shinhyeok; Bussek, Alexandra; Park, Tae Joo; Kim, Youni; Lee, Hyun-Shik; Pers, Tune H.; Kwon, Taejoon; Sedzinski, Jakub; Natarajan, Kedar Nath
err分享
err收藏
Peroxiredoxin 5 Inhibits Glutamate-Induced Neuronal Cell Death through the Regulation of Calcineurin-Dependent Mitochondrial Dynamics in HT22 Cells
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-03
err20
errOAAI
errKim, Mi Hye; Lee, Hong Jun; Lee, Sang-Rae; Lee, Hyun-Shik; Huh, Jae-Won; Bae, Yong Chul; Lee, Dong-Seok
err分享
err收藏
Carnitine Protects against MPP+-Induced Neurotoxicity and Inflammation by Promoting Primary Ciliogenesis in SH-SY5Y Cells
errCELLS
IF5.2
err2022-09-01
err11
errOAAI
errBae, Ji-Eun; Kim, Joon Bum; Jo, Doo Sin; Park, Na Yeon; Kim, Yong Hwan; Lee, Ha Jung; Kim, Seong Hyun; Kim, So Hyun; Son, Mikyung; Kim, Pansoo; Ryu, Hong-Yeoul; Lee, Won Ha; Ryoo, Zae Young; Lee, Hyun-Shik; Jung, Yong-Keun; Cho, Dong-Hyung
err分享
err收藏
GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base
errELIFE
IF0
err2022-08-25
err3
errOAAI
errJang, Dong Gil; Kwon, Keun Yeong; Kweon, Yeong Cheon; Kim, Byung-gyu; Myung, Kyungjae; Lee, Hyun-Shik; Park, Chan Young; Kwon, Taejoon; Park, Tae Joo
err分享
err收藏
Cathepsin D as a potential therapeutic target to enhance anticancer drug-induced apoptosis via RNF183-mediated destabilization of Bcl-xL in cancer cells
errCELL DEATH & DISEASE
IF9.6
err2022-02-04
err25
errOAAI
errSeo, Seung Un; Woo, Seon Min; Im, Seung-Soon; Jang, Younghoon; Han, Eugene; Kim, Sang Hyun; Lee, Hongchan; Lee, Hyun-Shik; Nam, Ju-Ock; Gabrielson, Edward; Min, Kyoung-Jin; Kwon, Taeg Kyu
err分享
err收藏
Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance
errSCIENCE ADVANCES
IF12.5
err2022-01-21
err16
errOAAI
errSim, Hyo Jung; Cho, Chanmi; Kim, Ha Eun; Hong, Ju Yeon; Song, Eun Kyung; Kwon, Keun Yeong; Jang, Dong Gil; Kim, Seok-Jung; Lee, Hyun-Shik; Lee, Changwook; Kwon, Taejoon; Yang, Siyoung; Park, Tae Joo
err分享
err收藏
Protective Effect of GIP against Monosodium Glutamate-Induced Ferroptosis in Mouse Hippocampal HT-22 Cells through the MAPK Signaling Pathway
errANTIOXIDANTS
IF6.6
err2022-01-19
err19
errOAAI
errKo, Jiwon; Jang, Soyoung; Kwon, Wookbong; Kim, Si-Yong; Jang, Soyeon; Kim, Eungyung; Ji, Young-Rae; Park, Sijun; Kim, Myoung-Ok; Choi, Seong-Kyoon; Cho, Dong-Hyung; Lee, Hyun-Shik; Lim, Su-Geun; Ryoo, Zae-Young
err分享
err收藏
Trans-tail regulation-mediated suppression of cryptic transcription
errEXPERIMENTAL AND MOLECULAR MEDICINE
IF12.9
err2021-11-29
err7
errOAAI
errChoi, Jungmin; Ryoo, Zae Young; Cho, Dong-Hyung; Lee, Hyun-Shik; Ryu, Hong-Yeoul
err分享
err收藏
Inhibition of cathepsin K sensitizes oxaliplatin-induced apoptotic cell death by Bax upregulation through OTUB1-mediated p53 stabilization in vitro and in vivo
errONCOGENE
IF7.3
err2021-11-16
err11
errOAAI
errSeo, Seung Un; Woo, Seon Min; Kim, Shin; Park, Jong-Wook; Lee, Hyun-Shik; Bae, Young-Seuk; Kim, Sang Hyun; Im, Seung-Soon; Seo, Ji Hae; Min, Kyoung-Jin; Kwon, Taeg Kyu
err分享
err收藏
Overexpression of Lin28a Aggravates Psoriasis-Like Phenotype by Regulating the Proliferation and Differentiation of Keratinocytes (vol 14, pg 4299, 2021)
errinflammation research
IF4.1
err2021-10-01
err0
errOAAI
errJang, Soyeon; Jang, Soyoung; Kim, Si-Yong; Ko, Jiwon; Kim, Eungyung; Park, Ji Yeong; Hyung, Hyejin; Lee, Jin Hong; Lim, Su-Geun; Park, Sijun; Yi, Junkoo; Lee, Heon-Jin; Kim, Myoung Ok; Lee, Hyun-Shik; Ryoo, Zae Young
err分享
err收藏

研究方向

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