Adrian J. Harwood - Publications, H-index & Citations

Adrian J. Harwood

cardiff university

42H指数

158论文数

6.3K被引数

收录论文 54

发表时间

CACNA1C genetic variants differentially affect neuronal networks through divergent pathways CACNA1C基因变异通过不同途径差异性影响神经元网络

Biological Psychiatry: Global Open Science

IF3.7

2026-07-22

OAAI

Gemma Wilkinson; Jamie Wood; Nuppu Roivainen; Josephine E. Haddon; Jack F.G. Underwood; Jeremy Hall; Adrian J. Harwood

Effects of acute fluctuations of extracellular Zinc on network activity of human iPSC-derived neurons; impact of NMDA Receptor and L-Type Calcium Channel Activation 急性细胞外锌波动对人类iPSC来源神经元网络活动的影响；NMDA受体和L型钙通道激活的作用

Neuropharmacology

IF4.6

2026-05-23

OAAI

Alsaqati, Mouhamed; Haddon, Josephine E.; Hall, Jeremy; Harwood, Adrian J.; Wilkinson, Lawrence S.

Human induced pluripotent stem cell-derived microglia with 1q21.1 deletion and duplication exhibit aberrant inflammatory response 人诱导多能干细胞来源的小胶质细胞，携带1q21.1缺失和重复，表现出异常的炎症反应

Genes & Diseases

IF9.4

2025-11-06

OAAI

Tanya Singh; Kubra Trabzonlu; Aleksandra Spasova; Phil Stephens; David E.J. Linden; Marianne B.M. van den Bree; Michael J. Owen; Jeremy Hall; Ujjwal Neogi; Adrian J. Harwood; Yasir Ahmed Syed

Loss of tuberous sclerosis complex 2 confers inflammation via dysregulation of nuclear factor kappa-light-chain-enhancer of activated B cells 结节性硬化复合物2的丢失通过核因子κB（nuclear factor kappa-light-chain-enhancer of activated B cells）的失调引发炎症。

Journal of Inflammation

IF10.1

2025-10-03

OAAI

Darius K. McPhail; Mohammad A.M. Alzahrani; Katie R. Martin; Brian L. Calver; Adrian J. Harwood; Jeffrey P. MacKeigan; David M. Davies; Andrew R. Tee

MINDDS-connect: a federated data platform integrating biobanks for meta cohort building and analysis MINDDS-connect：一个集成生物样本库的联邦数据平台，用于构建和分析元队列

European Journal of Human Genetics

IF4.6

2025-08-20

OAAI

Benjamin Huremagic; Nishkala Sattanathan; Mathilde Geysens; Janet Harwood; Jente Verbesselt; Senne Meynants; Ann Swillen; Kris Van Den Bogaert; Danijela Drakulic; Goran Cuturilo; Thérèse van Amelsvoort; David Linden; Natália Oliva-Teles; Paula Jorge; Marianne B. M. van den Bree; Jessica H. Hall; Haleh Chizari; Amin Ardeshirdavani; Adrian J. Harwood; Geert Vandeweyer; Yves Moreau; Joris Robert Vermeesch

MINDDS-CONNECT - FEDERATED DATA SHARING PLATFORM FOR NEURODEVELOPMENTAL DISORDERS AND RARE GENETIC MUTATIONS

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2023-10-01

PREAI

Mihaljevic, Marina; Huremagic, Benjamin; Harwood, Janet; Jorge, Paola; Teles, Natalia; Novakowska, Beata; Vandeweyer, Geert; Drakulic, Danijela; van Amelsvoort, Therese; Linden, David; Straccia, Marco; Vermeersch, Joris; Harwood, Adrian

NRSF/REST lies at the intersection between epigenetic regulation, miRNA-mediated gene control and neurodevelopmental pathways associated with Intellectual disability (ID) and Schizophrenia

TRANSLATIONAL PSYCHIATRY

IF6.2

2022-10-10

OAAI

Alsaqati, Mouhamed; Davis, Brittany A.; Wood, Jamie; Jones, Megan M.; Jones, Lora; Westwood, Aishah; Petter, Olena; Isles, Anthony R.; Linden, David; Van den Bree, Marianne; Owen, Michael; Hall, Jeremy; Harwood, Adrian J.

The association of neurodevelopmental abnormalities, congenital heart and renal defects in a tuberous sclerosis complex patient cohort

BMC MEDICINE

IF8.3

2022-04-20

OAAI

Robinson, Jessica; Uzun, Orhan; Loh, Ne Ron; Harris, Isabelle Rose; Woolley, Thomas E.; Harwood, Adrian J.; Gardner, Jennifer Frances; Syed, Yasir Ahmed

The genetic architecture underlying prey-dependent performance in a microbial predator

NATURE COMMUNICATIONS

IF15.7

2022-01-14

OAAI

Stewart, Balint; Gruenheit, Nicole; Baldwin, Amy; Chisholm, Rex; Rozen, Daniel; Harwood, Adrian; Wolf, Jason B.; Thompson, Christopher R. L.

Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants

NATURE COMMUNICATIONS

IF15.7

2022-01-14

OAAI

Sanders, Bret; D'Andrea, Daniel; Collins, Mark O.; Rees, Elliott; Steward, Tom G. J.; Zhu, Ying; Chapman, Gareth; Legge, Sophie E.; Pardinas, Antonio F.; Harwood, Adrian J.; Gray, William P.; O'Donovan, Michael C.; Owen, Michael J.; Errington, Adam C.; Blake, Derek J.; Whitcomb, Daniel J.; Pocklington, Andrew J.; Shin, Eunju

Using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion and duplication syndrome

MOLECULAR PSYCHIATRY

IF10.1

2021-06-10

OAAI

Chapman, Gareth; Alsaqati, Mouhamed; Lunn, Sharna; Singh, Tanya; Linden, Stefanie C.; Linden, David E. J.; van den Bree, Marianne B. M.; Ziller, Mike; Owen, Michael J.; Hall, Jeremy; Harwood, Adrian J.; Syed, Yasir Ahmed

Pharmacological intervention to restore connectivity deficits of neuronal networks derived from ASD patient iPSC with a TSC2 mutation

MOLECULAR AUTISM

IF5.5

2020-10-19

OAAI

Alsaqati, Mouhamed; Heine, Vivi M.; Harwood, Adrian J.

Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD

MOLECULAR AUTISM

IF5.5

2020-06-01

OAAI

Drakulic, Danijela; Djurovic, Srdjan; Syed, Yasir Ahmed; Trattaro, Sebastiano; Caporale, Nicolo; Falk, Anna; Ofir, Rivka; Heine, Vivi M.; Chawner, Samuel J. R. A.; Rodriguez-Moreno, Antonio; van den Bree, Marianne B. M.; Testa, Giuseppe; Petrakis, Spyros; Harwood, Adrian J.

A new mechanism for cannabidiol in regulating the one-carbon cycle and methionine levels in Dictyostelium and in mammalian epilepsy models

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2020-01-03

OAAI

Perry, Christopher J.; Finch, Paul; Muller-Taubenberger, Annette; Leung, Kit-Yi; Warren, Eleanor C.; Damstra-Oddy, Joseph; Sharma, Devdutt; Patra, Pabitra H.; Glyn, Sarah; Boberska, Joanna; Stewart, Balint; Baldwin, Amy; Piscitelli, Fabiana; Harvey, Robert J.; Harwood, Adrian; Thompson, Christopher; Claus, Sandrine P.; Greene, Nicholas D. E.; McNeish, Alister J.; Williams, Claire M.; Whalley, Benjamin J.; Williams, Robin S. B.

L-type voltage-gated calcium channel regulation of in vitro human cortical neuronal networks

SCIENTIFIC REPORTS

IF3.9

2019-09-25

OAAI

Plumbly, William; Brandon, Nick; Deeb, Tarek Z.; Hall, Jeremy; Harwood, Adrian J.

Nucleosome dynamics of human iPSC during neural differentiation 神经分化过程中人iPSC的核小体动力学

EMBO REPORTS

IF6.2

2019-04-29

OAAI

Harwood, Janet C.; Kent, Nicholas A.; Allen, Nicholas D.; Harwood, Adrian J.

Neuron-Glia Interactions Increase Neuronal Phenotypes in Tuberous Sclerosis Complex Patient iPSC-Derived Models

STEM CELL REPORTS

IF5.1

2019-01-01

OAAI

Nadadhur, Aishwarya G.; Alsaqati, Mouhamed; Gasparotto, Lisa; Cornelissen-Steijger, Paulien; van Hugte, Eline; Dooves, Stephanie; Harwood, Adrian J.; Heine, Vivi M.

Curcumin and derivatives function through protein phosphatase 2A and presenilin orthologues in Dictyostelium discoideum

DISEASE MODELS & MECHANISMS

IF3.3

2018-01-29

OAAI

Cocorocchio, Marco; Baldwin, Amy J.; Stewart, Balint; Kim, Lou; Harwood, Adrian J.; Thompson, Christopher R. L.; Andrews, Paul L. R.; Williams, Robin S. B.

Regulation of nucleosome positioning by a CHD Type III chromatin remodeler and its relationship to developmental gene expression in Dictyostelium

GENOME RESEARCH

IF5.5

2017-03-22

OAAI

Platt, James L.; Kent, Nicholas A.; Kimmel, Alan R.; Harwood, Adrian J.

Modeling psychiatric disorders: from genomic findings to cellular phenotypes (vol 21, pg 1167, 2016)

MOLECULAR PSYCHIATRY

IF10.1

2016-06-21

OAAI

Falk, A.; Heine, V. M.; Harwood, A. J.; Sullivan, P. F.; Peitz, M.; Brustle, O.; Shen, S.; Sun, Y-M; Glover, J. C.; Posthuma, D.; Djurovic, S.

研究方向