David Wheeler - Publications, H-index & Citations

David Wheeler

national institutes of health

32H指数

168论文数

2.0W被引数

收录论文 34

发表时间

Spliceosomal proteins direct RNA methylation to modulate gene expression and silence retrotransposons 剪接体蛋白指导RNA甲基化以调控基因表达并沉默反转座子

Nature Communications

IF15.7

2026-07-08

OAAI

Drisya Vijayakumari; Xander Gottfried; Brent Groubert; Jothy Dhakshnamoorthy; Shweta Jain; Martin Zofall; Hernan Diego Folco; Hua Xiao; Anupa T Anil; Thorkell Andresson; David Wheeler; Shiv I. S. Grewal

Stress controls heterochromatin inheritance via histone H3 ubiquitylation 应激通过组蛋白H3泛素化控制异染色质遗传

Nature

IF48.5

2026-01-07

OAAI

Bharat Bhatt; Yi Wei; Ashis Kumar Pradhan; Jothy Dhakshnamoorthy; Martin Zofall; Hua Xiao; Drisya Vijayakumari; Shweta Jain; Hernan Diego Folco; Hongyun Qi; David A. Ball; Tatiana S. Karpova; David Wheeler; Jiemin Wong; Shiv I. S. Grewal

Nucleosome remodeler exclusion by histone deacetylation enforces heterochromatic silencing and epigenetic inheritance 通过组蛋白脱乙酰作用排除核小体重塑剂会增强异色沉默和表观遗传

MOLECULAR CELL

IF16.6

2024-09-01

PREAI

Sahu, Rakesh Kumar; Dhakshnamoorthy, Jothy; Jain, Shweta; Folco, Hernan Diego; Wheeler, David; Grewal, Shiv I. S.

Specialized replication of heterochromatin domains ensures self- templated chromatin assembly and epigenetic inheritance 异染色质结构域的特化复制可确保染色质自模板化组装和表观遗传

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-01-29

OAAI

Nathanailidou, Patroula; Dhakshnamoorthy, Jothy; Xiao, Hua; Zofall, Martin; Holla, Sahana; O'Neill, Maura; Andresson, Thorkell; Wheeler, David; Grewal, Shiv I. S.

The cysteine-rich domain in CENP-A chaperone Scm3HJURP ensures centromere targeting and kinetochore integrity Cenp-a伴侣Scm3HJURP中富含半胱氨酸的结构域可确保着丝粒靶向和动粒完整性

NUCLEIC ACIDS RESEARCH

IF13.1

2023-12-12

OAAI

Folco, H. Diego; Xiao, Hua; Wheeler, David; Feng, Hanqiao; Bai, Yawen; Grewal, Shiv I. S.

Dynamic de novo heterochromatin assembly and disassembly at replication forks ensures fork stability

NATURE CELL BIOLOGY

IF19.1

2023-07-06

OAAI

Gaggioli, Vincent; Lo, Calvin S. Y.; Reveron-Gomez, Nazaret; Jasencakova, Zuzana; Domenech, Heura; Nguyen, Hong; Sidoli, Simone; Tvardovskiy, Andrey; Uruci, Sidrit; Slotman, Johan A.; Chai, Yi; Goncalves, Joao G. S. C. Souto; Manolika, Eleni Maria; Jensen, Ole N.; Wheeler, David; Sridharan, Sriram; Chakrabarty, Sanjiban; Demmers, Jeroen; Kanaar, Roland; Groth, Anja; Taneja, Nitika

Structural mechanism of LIN28B nucleosome by OCT4

MOLECULAR CELL

IF16.6

2023-06-01

OAAI

Guan, Ruifang; Lian, Tengfei; Zhou, Bing-Rui; Wheeler, David; Bai, Yawen

Histone deacetylation primes self-propagation of heterochromatin domains to promote epigenetic inheritance 组蛋白去乙酰化引发异染色质结构域的自我繁殖，以促进表观遗传

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2022-09-05

OAAI

Zofall, Martin; Sandhu, Rima; Holla, Sahana; Wheeler, David; Grewal, Shiv I. S.

Turning coldspots into hotspots: targeted recruitment of axis protein Hop1 stimulates meiotic recombination in Saccharomyces cerevisiae

GENETICS

IF5.1

2022-07-25

OAAI

Shodhan, Anura; Xaver, Martin; Wheeler, David; Lichten, Michael

Repeated strand invasion and extensive branch migration are hallmarks of meiotic recombination

MOLECULAR CELL

IF16.6

2021-10-01

OAAI

Ahuja, Jasvinder S.; Harvey, Catherine S.; Wheeler, David L.; Lichten, Michael

RNAi and Ino80 complex control rate limiting translocation step that moves rDNA to eroding telomeres

NUCLEIC ACIDS RESEARCH

IF13.1

2021-07-09

OAAI

Apte, Manasi S.; Masuda, Hirohisa; Wheeler, David Lee; Cooper, Julia Promisel

Spreading and epigenetic inheritance of heterochromatin require a critical density of histone H3 lysine 9 tri-methylation 异染色质的扩散和表观遗传需要组蛋白H3赖氨酸9三甲基化的临界密度

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-05-25

OAAI

DiPiazza, Amber R. Cutter; Taneja, Nitika; Dhakshnamoorthy, Jothy; Wheeler, David; Holla, Sahana; Grewal, Shiv I. S.

SMARCAD1-mediated active replication fork stability maintains genome integrity SMARCAD1-mediated活性复制叉稳定性维持基因组完整性

SCIENCE ADVANCES

IF12.5

2021-05-07

OAAI

Lo, Calvin Shun Yu; van Toorn, Marvin; Gaggioli, Vincent; Dias, Mariana Paes; Zhu, Yifan; Manolika, Eleni Maria; Zhao, Wei; van der Does, Marit; Mukherjee, Chirantani; Goncalves, Joao G. S. C. Souto; van Royen, Martin E.; French, Pim J.; Demmers, Jeroen; Smal, Ihor; Lans, Hannes; Wheeler, David; Jonkers, Jos; Chaudhuri, Arnab Ray; Marteijn, Jurgen A.; Taneja, Nitika

TOR targets an RNA processing network to regulate facultative heterochromatin, developmental gene expression and cell proliferation TOR靶向RNA加工网络来调节兼性异染色质，发育基因表达和细胞增殖

NATURE CELL BIOLOGY

IF19.1

2021-02-11

OAAI

Wei, Yi; Lee, Nathan N.; Pan, Lixia; Dhakshnamoorthy, Jothy; Sun, Ling-Ling; Zofall, Martin; Wheeler, David; Grewal, Shiv I. S.

Conserved protein Pir2ARS2 mediates gene repression through cryptic introns in lncRNAs 保守蛋白Pir2ARS2通过lncRNAs中的隐性内含子介导基因抑制

NATURE COMMUNICATIONS

IF15.7

2020-05-15

OAAI

Thillainadesan, Gobi; Xiao, Hua; Holla, Sahana; Dhakshnamoorthy, Jothy; Jenkins, Lisa M. Miller; Wheeler, David; Grewal, Shiv I. S.

CPF Recruitment to Non-canonical Transcription Termination Sites Triggers Heterochromatin Assembly and Gene Silencing CPF募集到非经典转录终止位点触发异染色质组装和基因沉默

CELL REPORTS

IF6.9

2019-07-01

OAAI

Vo, Tommy V.; Dhakshnamoorthy, Jothy; Larkin, Madeline; Zofall, Martin; Thillainadesan, Gobi; Balachandran, Vanivilasini; Holla, Sahana; Wheeler, David; Grewal, Shiv I. S.

Genomic Heterogeneity Within Individual Prostate Cancer Foci Impacts Predictive Biomarkers of Targeted Therapy

EUROPEAN UROLOGY FOCUS

IF5.6

2019-05-01

OAAI

VanderWeele, David J.; Finney, Richard; Katayama, Kotoe; Gillard, Marc; Paner, Gladell; Imoto, Seiya; Yamaguchi, Rui; Wheeler, David; Lack, Justin; Cam, Maggie; Pontier, Andrea; Yen Thi Minh Nguyen; Maejima, Kazuhiro; Sasaki-Oku, Aya; Nakano, Kaoru; Tanaka, Hiroko; Vander Griend, Donald; Kubo, Michiaki; Ratain, Mark J.; Miyano, Satoru; Nakagawa, Hidewaki

Multi-Locus Next-Generation Sequence Typing of DNA Extracted From Pooled Colonies Detects Multiple Unrelated Candida albicans Strains in a Significant Proportion of Patient Samples

FRONTIERS IN MICROBIOLOGY

IF4.5

2018-06-05

OAAI

Zhang, Ningxin; Wheeler, David; Truglio, Mauro; Lazzarini, Cristina; Upritchard, Jenine; McKinney, Wendy; Rogers, Karen; Prigitano, Anna; Tortorano, Anna M.; Cannon, Richard D.; Broadbent, Roland S.; Roberts, Sally; Schmid, Jan

Iron homeostasis regulates facultative heterochromatin assembly in adaptive genome control 铁稳态在适应性基因组控制中调节兼性异染色质组装

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2018-04-23

OAAI

Gallagher, Pamela S.; Larkin, Madeline; Thillainadesan, Gobi; Dhakshnamoorthy, Jothy; Balachandran, Vanivilasini; Xiao, Hua; Wellman, Christopher; Chatterjee, Raghunath; Wheeler, David; Grewal, Shiv I. S.

Targeted deep sequencing of colorectal tumor tissues to study associations of tumor subtypes with germline genetic, lifestyle, and environmental risk factors

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Zaidi, Syed H.; Sun, Wei; Huyghe, Jeroen; Grasso, Catherine S.; Quang Trinh; Connolly, Charles; French, Amy; Mu, Jasmine; Giannakis, Marios; Shinbrot, Eve; Borozan, Ivan; Quist, Michael J.; Brenner, Hermann; Buchanan, Daniel; Campbell, Peter; Chan, Andrew; Chang-Claude, Jenny; Ferretti, Vincent; Fuchs, Charles; Gsur, Andrea; Gunter, Marc; Harrison, Tabitha; Hoffmeister, Michael; Huang, Wen-Yi; Krzyzanowski, Paul; Lee, Stephen; Lemire, Mathieu; Miller, Jessica; Pasternack, Danielle; Teney, Cherie; Mardis, Elaine; Newcomb, Polly; Stein, Lincoln; Timms, Lee; Wheeler, David; Yung, Christina; Zubair, Niha; Garraway, Levi; Ogino, Shuji; Hsu, Li; Gallinger, Steven; Thibodeau, Stephen; Hudson, Thomas; Peters, Ulrike

研究方向