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Impaired GABAergic regulation and developmental immaturity in interneurons derived from the medial ganglionic eminence in the tuberous sclerosis complex Scheper, Mirte; Sorensen, Frederik N. F.; Ruffolo, Gabriele; Gaeta, Alessandro; Lissner, Lilian J.; Anink, Jasper J.; Korshunova, Irina; Jansen, Floor E.; Riney, Kate; van Hecke, Wim; Muehlebner, Angelika; Khodosevich, Konstantin; Schubert, Dirk; Palma, Eleonora; Mills, James D.; Aronica, Eleonora 分享 收藏
A human in vitro neuronal model for studying homeostatic plasticity at the network level Yuan, Xiuming; Puvogel, Sofia; van Rhijn, Jon-Ruben; Ciptasari, Ummi; Esteve-Codina, Anna; Meijer, Mandy; Rouschop, Simon; Hugte, Eline J. H. van; Oudakker, Astrid; Schoenmaker, Chantal; Frega, Monica; Schubert, Dirk; Franke, Barbara; Kasri, Nael Nadif 分享 收藏
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SCN1A-deficient excitatory neuronal networks display mutation-specific phenotypes van Hugte, Eline J. H.; Lewerissa, Elly, I; Wu, Ka Man; Scheefhals, Nicky; Parodi, Giulia; van Voorst, Torben W.; Puvogel, Sofia; Kogo, Naoki; Keller, Jason M.; Frega, Monica; Schubert, Dirk; Schelhaas, Helenius J.; Verhoeven, Judith; Majoie, Marian; van Bokhoven, Hans; Nadif Kasri, Nael 分享 收藏
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Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway 精神分裂症风险基因SETD1A的功能丧失变体通过cAMP/PKA途径改变人类神经元的神经元网络活性 Wang, Shan; van Rhijn, Jon-Ruben; Akkouh, Ibrahim; Kogo, Naoki; Maas, Nadine; Bleeck, Anna; Ortiz, Irene Santisteban; Lewerissa, Elly; Wu, Ka Man; Schoenmaker, Chantal; Djurovic, Srdjan; van Bokhoven, Hans; Kleefstra, Tjitske; Kasri, Nael Nadif; Schubert, Dirk 分享 收藏
Brunner syndrome associated MAOA mutations result in NMDAR hyperfunction and increased network activity in human dopaminergic neurons Van Rhijn, Jon-Ruben; Shi, Yan; Bormann, Maren; Mossink, Britt; Frega, Monica; Recaioglu, Hatice; Hakobjan, Marina; Gunnewiek, Teun Klein; Schoenmaker, Chantal; Palmer, Elizabeth; Faivre, Laurence; Kittel-Schneider, Sarah; Schubert, Dirk; Brunner, Han; Franke, Barbara; Kasri, Nael Nadif 分享 收藏
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Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro Mossink, Britt; Verboven, Anouk H. A.; van Hugte, Eline J. H.; Gunnewiek, Teun M. Klein; Parodi, Giulia; Linda, Katrin; Schoenmaker, Chantal; Kleefstra, Tjitske; Kozicz, Tamas; van Bokhoven, Hans; Schubert, Dirk; Kasri, Nael Nadif; Frega, Monica 分享 收藏
Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders 不平衡的自噬在神经发育障碍的人类模型中引起突触缺陷 Linda, Katrin; Lewerissa, Elly I.; Verboven, Anouk H. A.; Gabriele, Michele; Frega, Monica; Klein Gunnewiek, Teun M.; Devilee, Lynn; Ulferts, Edda; Hommersom, Marina; Oudakker, Astrid; Schoenmaker, Chantal; van Bokhoven, Hans; Schubert, Dirk; Testa, Giuseppe; Koolen, David A.; de Vries, Bert B. A.; Nadif Kasri, Nael 分享 收藏
Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks Mossink, Britt; Van Rhijn, Jon-Ruben; Wang, Shan; Linda, Katrin; Vitale, Maria R.; Zoller, Johanna E. M.; van Hugte, Eline J. H.; Bak, Jitske; Verboven, Anouk H. A.; Selten, Martijn; Negwer, Moritz; Latour, Brooke L.; van der Werf, Ilse; Keller, Jason M.; Gunnewiek, Teun M. Klein; Schoenmaker, Chantal; Oudakker, Astrid; Anania, Alessia; Jansen, Sophie; Lesch, Klaus-Peter; Frega, Monica; van Bokhoven, Hans; Schubert, Dirk; Kasri, Nael Nadif 分享 收藏
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Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome 人类和果蝇中SETD1A单倍功能不全的表征定义了一种新的神经发育综合征 Kummeling, Joost; Stremmelaar, Diante E.; Raun, Nicholas; Reijnders, Margot R. F.; Willemsen, Marjolein H.; Ruiterkamp-Versteeg, Martina; Schepens, Marga; Man, Calvin C. O.; Gilissen, Christian; Cho, Megan T.; McWalter, Kirsty; Sinnema, Margje; Wheless, James W.; Simon, Marleen E. H.; Genetti, Casie A.; Casey, Alicia M.; Terhal, Paulien A.; van Der Smagt, Jasper J.; van Gassen, Koen L., I; Joset, Pascal; Bahr, Angela; Steindl, Katharina; Rauch, Anita; Keller, Elmar; Raas-Rothschild, Annick; Koolen, David A.; Agrawal, Pankaj B.; Hoffman, Trevor L.; Powell-Hamilton, Nina N.; Thiffault, Isabelle; Engleman, Kendra; Zhou, Dihong; Bodamer, Olaf; Hoefele, Julia; Riedhammer, Korbinian M.; Schwaibold, Eva M. C.; Tasic, Velibor; Schubert, Dirk; Top, Deniz; Pfundt, Rolph; Higgs, Martin R.; Kramer, Jamie M.; Kleefstra, Tjitske 分享 收藏
m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity Gunnewiek, Teun M. Klein; Van Hugte, Eline J. H.; Frega, Monica; Guardia, Gemma Sole; Foreman, Katharina; Panneman, Daan; Mossink, Britt; Linda, Katrin; Keller, Jason M.; Schubert, Dirk; Cassiman, David; Rodenburg, Richard; Folch, Noemi Vidal; Oglesbee, Devin; Perales-Clemente, Ester; Nelson, Timothy J.; Morava, Eva; Kasri, Nael Nadif; Kozicz, Tamas 分享 收藏
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