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Bente Frølund

university of copenhagen

33H指数
200论文数
3.9K被引数
收录论文 97
发表时间
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Exploring the DS2 Scaffold for GABAA Receptor Modulation: Progress toward the Development of a GABAA δ-Subunit Preferring Negative Allosteric Modulator探索用于GABAA受体调节的DS2支架: GABAA δ 亚基偏好负变构调节剂的开发进展
errJournal of Medicinal Chemistry
IF6.8
err2026-02-02
err0
PREAI
errNicoline N. Jensen; Kristine S. Wilhelmsen; Malene Hall Jensen; Sandrine Mentgen; Francesco Bavo; Uffe Kristiansen; Petrine Wellendorph; Bente Frølund
err分享
err收藏
Structural basis for selective inhibition of human GABA transporter GAT3选择性抑制人GABA转运蛋白GAT3的结构基础
errNature Communications
IF15.7
err2026-01-29
err0
errOAAI
errJonas Sigurd Mortensen; Francesco Bavo; Malene Hall Jensen; Alexander Peder Smiszek Pedersen; Julian Philipp Storm; Tillmann Pape; Bente Frølund; Petrine Wellendorph; Azadeh Shahsavar
err分享
err收藏
2-Benzyl-6-carboxy-5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidin-1-ium 2,2,2-trifluoroacetate
errMOLBANK
IF0.4
err2025-10-20
err0
errOAAI
errBavo, Francesco; Avgerinos, Christos; Martino, Elena; Frolund, Bente
err分享
err收藏
Fluorescent Isostere (Fluostere) of the Carboxylate: Design of hDHODH Fluorescent Inhibitors as Proof of Concept羧酸根的荧光同系物(荧光同位体)：作为概念验证的人DHODH荧光抑制剂的研制
errJournal of Medicinal Chemistry
IF6.8
err2025-06-18
err0
errOAAI
errStefano Sainas; Elena Martino; Claudio Garino; Paola Circosta; Anna Luganini; Marta Giorgis; Francesco Bavo; Marco Piccinini; Cristina Ramondetti; Marta Alberti; Riccardo Miggiano; Giorgio Gribaudo; Donatella Boschi; Bente Frølund; Marco Lucio Lolli
err分享
err收藏
International Union of Basic and Clinical Pharmacology. CXX. γ-Hydroxybutyrate protein targets in the mammalian brain—beyond classic receptors国际基础和临床药理学联合会。CXX. 哺乳动物大脑中γ-羟基丁酸的蛋白质靶点——超越经典受体
errPharmacological Reviews
IF17.3
err2025-05-05
err0
PREAI
errPetrine Wellendorph; Stine Juul Gauger; Jens Velde Andersen; Birgitte Rahbek Kornum; Sara M.O. Solbak; Bente Frølund
err分享
err收藏
Structural Determinants of Oxantel Analogs Reveal Modulatory Selectivity of α3β2 and α4β2 Neuronal Nicotinic Acetylcholine Receptors
errACS OMEGA
IF4.3
err2025-02-12
err0
errOAAI
errBavo, Francesco; Chechik, Lucy; Huynh, Khoa; Kolanowski, Anna; Richardson, Avery; Tardrew, Sydney; Basrur, Nipun; Levandoski, Mark M.; Frolund, Bente
err分享
err收藏
Muscimol inhibits plasma membrane rupture and ninjurin-1(NINJ1) oligomerization during pyroptosis (vol 6, 1010, 2023)
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-03-11
err0
errOAAI
errden Hartigh, Andreas B.; Loomis, Wendy P.; Anderson, Marisa J.; Frolund, Bente; Fink, Susan L.
err分享
err收藏
Muscimol inhibits plasma membrane rupture and ninjurin-1 oligomerization during pyroptosis
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-10-05
err11
errOAAI
errden Hartigh, Andreas B.; Loomis, Wendy P.; Anderson, Marisa J.; Frolund, Bente; Fink, Susan L.
err分享
err收藏
Pregnenolone sulfate analogues differentially modulate GABAA receptor closed/desensitised states
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2023-06-02
err3
errOAAI
errMortensen, Martin; Xu, Yue; Shehata, Mohamed A.; Krall, Jacob; Ernst, Margot; Frolund, Bente; Smart, Trevor G.
err分享
err收藏
The CaMKIIα hub ligand Ph-HTBA promotes neuroprotection after focal ischemic stroke by a distinct molecular interaction
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2022-12-01
err6
PREAI
errGriem-Krey, Nane; Gauger, Stine J.; Gowing, Emma K.; Thiesen, Louise; Frolund, Bente; Clarkson, Andrew N.; Wellendorph, Petrine
err分享
err收藏
Exploring the NCS-382 Scaffold for CaMKIIα Modulation: Synthesis, Biochemical Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant Stabilizer of the CaMKIIα Hub Domain
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-11-08
err5
PREAI
errTian, Yongsong; Shehata, Mohamed A.; Gauger, Stine Juul; Veronesi, Carolina; Hamborg, Louise; Thiesen, Louise; Bruus-Jensen, Jesper; Royssen, Johanne Schlieper; Leurs, Ulrike; Larsen, Anne Sofie G.; Krall, Jacob; Solbak, Sara M. O.; Wellendorph, Petrine; Frolund, Bente
err分享
err收藏
? Discovery and Optimization of 5-Hydroxy-Diclofenac toward a New Class of Ligands with Nanomolar Affinity for the CaMKII? Hub Domain
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-05-02
err5
PREAI
errTian, Yongsong; Shehata, Mohamed A.; Gauger, Stine Juul; Ng, Clarissa K. L.; Solbak, Sara; Thiesen, Louise; Bruus-Jensen, Jesper; Krall, Jacob; Bundgaard, Christoffer; Gibson, K. Michael; Wellendorph, Petrine; Frolund, Bente
err分享
err收藏
Structure-Activity Studies of 3,9-Diazaspiro[5.5]undecane-Based γ-Aminobutyric Acid Type A Receptor Antagonists with Immunomodulatory Effect
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-12-15
err3
errOAAI
errBavo, Francesco; De-Jong, Heleen; Petersen, Jonas; Falk-Petersen, Christina Birkedahl; Loeffler, Rebekka; Sparrow, Emma; Rostrup, Frederik; Eliasen, Jannik Nicklas; Wilhelmsen, Kristine S.; Barslund, Kasper; Bundgaard, Christoffer; Nielsen, Birgitte; Kristiansen, Uffe; Wellendorph, Petrine; Bogdanov, Yury; Frolund, Bente
err分享
err收藏
Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1
errFRONTIERS IN CHEMISTRY
IF4.2
err2021-09-14
err6
errOAAI
errKickinger, Stefanie; Lie, Maria E. K.; Suemasa, Akihiro; Al-Khawaja, Anas; Fujiwara, Koichi; Watanabe, Mizuki; Wilhelmsen, Kristine S.; Falk-Petersen, Christina B.; Frolund, Bente; Shuto, Satoshi; Ecker, Gerhard F.; Wellendorph, Petrine
err分享
err收藏
GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2021-07-30
err32
errOAAI
errLeurs, Ulrike; Klein, Anders B.; McSpadden, Ethan D.; Griem-Krey, Nane; Solbak, Sara M. O.; Houlton, Josh; Villumsen, Inge S.; Vogensen, Stine B.; Hamborg, Louise; Gauger, Stine J.; Palmelund, Line B.; Larsen, Anne Sofie G.; Shehata, Mohamed A.; Kelstrup, Christian D.; Olsen, Jesper, V; Bach, Anders; Burnie, Robert O.; Kerr, D. Steven; Gowing, Emma K.; Teurlings, Selina M. W.; Chi, Chris C.; Gee, Christine L.; Frolund, Bente; Kornum, Birgitte R.; van Woerden, Geeske M.; Clausen, Rasmus P.; Kuriyan, John; Clarkson, Andrew N.; Wellendorph, Petrine
err分享
err收藏
Molecular Determinants Underlying Delta Selective Compound 2 Activity at δ-Containing GABAA Receptors
errMOLECULAR PHARMACOLOGY
IF3
err2021-07-01
err3
errOAAI
errFalk-Petersen, Christina B.; Rostrup, Frederik; Loffler, Rebekka; Buchleithner, Stine; Harpsoe, Kasper; Gloriam, David E.; Frolund, Bente; Wellendorph, Petrine
err分享
err收藏
Structural Determinants for the Mode of Action of Imidazopyridine DS2 at δ-Containing γ-Aminobutyric Acid Type A Receptors
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-04-13
err7
PREAI
errRostrup, Frederik; Falk-Petersen, Christina B.; Harpsoe, Kasper; Buchleithner, Stine; Conforti, Irene; Jung, Sascha; Gloriam, David E.; Schirmeister, Tanja; Wellendorph, Petrine; Frolund, Bente
err分享
err收藏
Exploring the molecular determinants for subtype-selectivity of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate-inhibitors
errSCIENTIFIC REPORTS
IF3.9
err2020-08-03
err5
errOAAI
errKickinger, Stefanie; Al-Khawaja, Anas; Haugaard, Anne Staehr; Lie, Maria E. K.; Bavo, Francesco; Loeffler, Rebekka; Damgaard, Maria; Ecker, Gerhard F.; Frolund, Bente; Wellendorph, Petrine
err分享
err收藏
Silencing of spontaneous activity at α4β1/3δ GABAAreceptors in hippocampal granule cells reveals different ligand pharmacology
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2020-07-15
err8
errOAAI
errDalby, Nils Ole; Falk-Petersen, Christina Birkedahl; Leurs, Ulrike; Scholze, Petra; Krall, Jacob; Frolund, Bente; Wellendorph, Petrine
err分享
err收藏
Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABAA receptors
errSCIENTIFIC REPORTS
IF3.9
err2020-06-22
err11
errOAAI
errFalk-Petersen, Christina Birkedahl; Tsonkov, Tsonko M.; Nielsen, Malene Sofie; Harpsoe, Kasper; Bundgaard, Christoffer; Frolund, Bente; Kristiansen, Uffe; Gloriam, David E.; Wellendorph, Petrine
err分享
err收藏

研究方向

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合作学者
合作期刊
J
John F. Cryan
H 指数: 162 · 论文数: 1.3K
J
J. Andrew McCammon
H 指数: 134 · 论文数: 1.1K
J
John Kuriyan
H 指数: 110 · 论文数: 407
J
Jesper V. Olsen
H 指数: 103 · 论文数: 658
A
Arne Schousboe
H 指数: 102 · 论文数: 704
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