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H

Héctor H. Valdivia

University of Wisconsin-Madison School of Medicine and Public Health

57H指数
262论文数
9.7K被引数
收录论文 113
发表时间
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Single-Residue Substitution of Opicalcin1 Enhances Cellular Uptake but Reduces Ca2+-Release ActivityOpicalcin1的单氨基酸替换增强了细胞摄取但降低了Ca2+-释放活性
errChemBioChem
IF2.8
err2026-09-21
err0
PREAI
errShumin Wang; Xiaoyu Hua; Xiaofen Ma; Lianbo Wang; Jianguo Wang; Hao Liu; Fei Nie; Yangfei Zhao; Qiuming Zhou; Héctor H. Valdivia; Liang Xiao; Jinming Wang
err分享
err收藏
Cryo-electron microscopy reveals sequential binding and activation of Ryanodine Receptors by statin triplets冷冻电子显微镜揭示了Statins三聚体对Ryanodine受体的顺序结合与激活
errNature Communications
IF15.7
err2025-11-20
err0
errOAAI
errSteven Molinarolo; Carmen R. Valdivia; Héctor H. Valdivia; Filip Van Petegem
err分享
err收藏
OpiCa1 Modulates Cardiomyocyte Viability Through PI3K/Akt Inhibition with Minimal Systemic Impact Beyond RyR TargetingOpiCa1通过抑制PI3K/Akt通路调节心肌细胞活力，且在靶向RyR之外具有极小的全身影响
errToxins 2025, Vol. 17, Page 550
IF4
err2025-11-04
err0
errOAAI
errXiaofen Ma; Xiaoyu Hua; Xiao Peng; Zhixiao Yang; Yi Wang; Qian Zhang; Lianbo Wang; Shumin Wang; Héctor H. Valdivia; Liang Xiao; Mei Wang
err分享
err收藏
Preventing the phosphorylation of RyR2 at canonical sites reduces Ca2+ leak and promotes arrhythmia by reactivating the INa current通过抑制RyR2在经典位点的磷酸化，能够减少Ca2+泄漏并通过重新激活INa电流来促进心律失常。
errcardiovascular research
IF10.8
err2025-08-12
err0
errOAAI
errJingjing Zheng; Daniela Ponce-Balbuena; Erick B. Ríos Pérez; Li Xiao; Holly C. Dooge; Héctor H. Valdivia; Francisco J. Alvarado
err分享
err收藏
OpiCa1 reduces inflammation and ROS levels counteracting heat stress-induced cardiac injuryOpiCa1可减轻炎症和ROS水平，对抗热应激诱导的心脏损伤
errEUROPEAN JOURNAL OF PHARMACOLOGY
IF4.7
err2025-07-01
err0
PREAI
errYang, Zhixiao; Hua, Xiaoyu; Wang, Fei; Wang, Yi; Hou, Xiaochuan; Yang, Fengling; Chen, Xiaoxiao; Liu, Tianwen; Ma, Xiaofen; Valdivia, Hector H.; Xiao, Liang; Li, Baojing
err分享
err收藏
Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals sub-conductance that is abolished by PKA phosphorylation
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errHaji-Ghassemi, Omid; Van Petegem, Filip; Valdivia, Hector; Chen, Seby; Woll, Kellie; Gurrola, Giorgina; Valdivia, Carmen; Cai, Wenxuan; Li, Songhua
err分享
err收藏
Comparison of the structure-function of five newly members of the calcin family
errINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
IF8.5
err2024-03-01
err1
PREAI
errHua, Xiaoyu; Yao, Jinchi; Liu, Xinyan; Liu, Qing; Deng, Yuchen; Li, Songhua; Valdivia, Carmen R.; Wang, Fei; Pozzolini, Marina; Shou, Zhaoyong; Valdivia, Hector H.; Xiao, Liang
err分享
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Phosphorylation of RyR2 simultaneously expands the dyad and rearranges the tetramers
errJOURNAL OF GENERAL PHYSIOLOGY
IF2.9
err2024-02-22
err3
errOAAI
errAsghari, Parisa; Scriven, David R. L.; Shahrasebi, Saba; Valdivia, Hector H.; Alsina, Katherina M.; Valdivia, Carmen R.; Navarro-Garcia, J. Alberto; Wehrens, Xander H. T.; Moore, Edwin D. W.
err分享
err收藏
Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2023-07-13
err7
errOAAI
errTito, Claudia; Genovese, Ilaria; Giamogante, Flavia; Benedetti, Anna; Miglietta, Selenia; Barazzuol, Lucia; Cristiano, Loredana; Iaiza, Alessia; Carolini, Sabatino; De Angelis, Luciana; Masciarelli, Silvia; Nottola, Stefania Annarita; Familiari, Giuseppe; Petrozza, Vincenzo; Lauriola, Mattia; Tamagnone, Luca; Ilari, Andrea; Cali, Tito; Valdivia, Hector H.; Valdivia, Carmen R.; Colotti, Gianni; Fazi, Francesco
err分享
err收藏
Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation
errSCIENCE ADVANCES
IF12.5
err2023-05-26
err8
errOAAI
errHaji-Ghassemi, Omid; Chen, Yu Seby; Woll, Kellie; Gurrola, Georgina B.; Valdivia, Carmen R.; Cai, Wenxuan; Li, Songhua; Valdivia, Hector H.; Van Petegem, Filip
err分享
err收藏
Preserved cardiac performance and adrenergic response in a rabbit model with decreased ryanodine receptor 2 expression
errJOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
IF4.7
err2022-12-01
err0
PREAI
errZheng, Jingjing; Dooge, Holly; Perez-Hernandez, Marta; Zhao, Yan-Ting; Chen, Xi; Valdivia, Carmen; Palomeque, Julieta; Rothenberg, Eli; Delmar, Mario; Valdivia, Hector; Alvarado, Francisco
err分享
err收藏
Molecular and functional characterization of a novel mutation in the cardiac ryanodine receptor (RyR2) associated with long QT syndrome
errJOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
IF4.7
err2022-12-01
err0
PREAI
errValdivia, Carmen; Cai, Wenxuan; Li, Songhua; Alvarado, Francisco; Zheng, Jingjing; Booher, Talia; Villareal-Molina, Teresa; Iturralde, Pedro; Medeiros-Domingo, Argelia; Valdivia, Hector
err分享
err收藏
Preserved cardiac performance and adrenergic response in a rabbit model with decreased ryanodine receptor 2 expression
errJOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
IF4.7
err2022-06-01
err9
errOAAI
errZheng, Jingjing; Dooge, Holly C.; Perez-Hernandez, Marta; Zhao, Yan-Ting; Chen, Xi; Hernandez, Jonathan J.; Valdivia, Carmen R.; Palomeque, Julieta; Rothenberg, Eli; Delmar, Mario; Valdivia, Hector H.; Alvarado, Francisco J.
err分享
err收藏
Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT MutationCPVT突变中与Junctophilin-2的结合受损和纳米结构改变
errCIRCULATION RESEARCH
IF16.2
err2021-07-23
err20
errOAAI
errYin, Liheng; Zahradnikova, Alexandra, Jr.; Rizzetto, Riccardo; Boncompagni, Simona; de Meritens, Camille Rabesahala; Zhang, Yadan; Joanne, Pierre; Marques-Sule, Elena; Aguilar-Sanchez, Yuriana; Fernandez-Tenorio, Miguel; Villejoubert, Olivier; Li, Linwei; Wang, Yue Yi; Mateo, Philippe; Nicolas, Valerie; Gerbaud, Pascale; Lai, F. Anthony; Perrier, Romain; Alvarez, Julio L.; Niggli, Ernst; Valdivia, Hector H.; Valdivia, Carmen R.; Ramos-Franco, Josefina; Zorio, Esther; Zissimopoulos, Spyros; Protasi, Feliciano; Benitah, Jean-Pierre; Gomez, Ana M.
err分享
err收藏
The Ca2+-binding protein sorcin stimulates transcriptional activity of the unfolded protein response mediator ATF6Ca2结合蛋白sorcin刺激未折叠蛋白反应介体ATF6的转录活性
errFEBS LETTERS
IF3
err2021-05-24
err4
errOAAI
errParks, Steven Z.; Gao, Tian; Awuapura, Natalia Jimenez; Ayathamattam, Joseph; Chabosseau, Pauline L.; Kalvakolanu, Dhananjaya, V; Valdivia, Hector H.; Rutter, Guy A.; Leclerc, Isabelle; Nakatogawa, Hitoshi
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err收藏
Imperacalcin-Induced Reduction of Sarcoplasmic Reticulum Ca2+in Intact Mouse Heart
errFASEB JOURNAL
IF4.2
err2021-05-14
err1
PREAI
errHammam, Noor; Valdivia, Hector; Mejia-Alvarez, Rafael
err分享
err收藏
Autonomous activation of CaMKII exacerbates diastolic calcium leak during beta-adrenergic stimulation in cardiomyocytes of metabolic syndrome rats
errCELL CALCIUM
IF4
err2020-11-01
err6
errOAAI
errRomero-Garcia, Tatiana; Landa-Galvan, Huguet, V; Pavon, Natalia; Mercado-Morales, Martha; Valdivia, Hector H.; Rueda, Angelica
err分享
err收藏
Tetrodotoxin-Sensitive Neuronal-Type Na+ Channels: A Novel and Druggable Target for Prevention of Atrial Fibrillation
errJOURNAL OF THE AMERICAN HEART ASSOCIATION
IF5.3
err2020-06-02
err15
errOAAI
errMunger, Mark A.; Olgar, Yusuf; Koleske, Megan L.; Struckman, Heather L.; Mandrioli, Jessica; Lou, Qing; Bonila, Ingrid; Kim, Kibum; Mondragon, Roberto Ramos; Priori, Silvia G.; Volpe, Pompeo; Valdivia, Hector H.; Biskupiak, Joseph; Carnes, Cynthia A.; Veeraraghavan, Rengasayee; Gyorke, Sandor; Radwanski, Przemyslaw B.
err分享
err收藏
Desmosome-Dyad Crosstalk: An Arrhythmogenic Axis in Arrhythmogenic Right Ventricular Cardiomyopathy
errCIRCULATION
IF38.6
err2020-05-05
err6
errOAAI
errDelmar, Mario; Alvarado, Francisco J.; Valdivia, Hector H.
err分享
err收藏
Disruption of Ca2+i Homeostasis and Connexin 43 Hemichannel Function in the Right Ventricle Precedes Overt Arrhythmogenic Cardiomyopathy in Plakophilin-2-Deficient Mice
errCIRCULATION
IF38.6
err2019-09-17
err89
errOAAI
errKim, Joon-Chul; Perez-Hernandez, Marta; Alvarado, Francisco J.; Maurya, Svetlana R.; Montnach, Jerome; Yin, Yandong; Zhang, Mingliang; Lin, Xianming; Vasquez, Carolina; Heguy, Adriana; Liang, Feng-Xia; Woo, Sun-Hee; Morley, Gregory E.; Rothenberg, Eli; Lundby, Alicia; Valdivia, Hector H.; Cerrone, Marina; Delmar, Mario
err分享
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