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李卫华 封面图

李卫华 (Weihua Li)

school of medicine

53H指数
322论文数
1.5W被引数
收录论文 169
发表时间
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Early post-infarct fibroblast activation protein-targeted PET/CT with 68Ga-FAPI-46 identifies STEMI patients with preserved LVEF at higher risk for adverse remodeling and cardiovascular events急性心梗早期FAPI-46靶向成纤维细胞活化蛋白PET/CT显像可识别左室射血分数保留的STEMI患者中不良重塑和心血管事件的高风险患者
errEuropean Journal of Nuclear Medicine and Molecular Imaging
IF7.6
err2026-07-21
err0
PREAI
errLing Liang; Lingyu Yu; Dan Ruan; Weiling Xu; Qiang Xie; Weihua Li; Xiaodong Huang; Jiangmu Deng; Yiquan Huang; Wuyang Zheng; Haojun Chen
err分享
err收藏
Study on NGS-based molecular profiling of malignant pleural effusion supernatant cfDNA in guiding targeted therapy for non-small cell lung cancer基于NGS的恶性胸腔积液上清液cfDNA分子分型在指导非小细胞肺癌靶向治疗中的研究
errLung Cancer
IF4.4
err2026-05-19
err0
errOAAI
errYuan Wang; Shuo Liang; Jia-Meng Zhang; Zi-Han Sun; Wei-Hua Li; Yue Sun; Cong Wang; Xin-Xiang Chang; Lin-Lin Zhao; Huan Zhao; Hui-Qin Guo; Zhi-Hui Zhang
err分享
err收藏
ULCYP: A Multitask Model for Predicting P450 Inducers Based on Positive-Unlabeled LearningULCYP：一种基于正负样本学习预测P450诱导物的多任务模型
errJournal of Chemical Information and Modeling
IF5.3
err2026-05-12
err0
PREAI
errChangda Gong; Jiaojiao Fang; Guixia Liu; Yun Tang; Weihua Li
err分享
err收藏
CypGEM: A Geometry-Aware and Edge-Enhanced Graph Transformer Model for Predicting Sites of Metabolism Mediated by Cytochromes P450CypGEM：一种几何感知和边缘增强的图Transformer模型，用于预测细胞色素P450介导的代谢位点
errJournal of Chemical Information and Modeling
IF5.3
err2026-05-04
err0
PREAI
errYuxin Zhang; Yingjie Yang; Meiling Zhan; Guixia Liu; Yun Tang; Weihua Li
err分享
err收藏
EviCYP: In Silico Prediction of Cytochrome P450 Substrates Based on Vector Quantization and Evidential Deep LearningEviCYP：基于向量量化与证据深度学习的细胞色素P450底物体外预测
errJournal of Chemical Information and Modeling
IF5.3
err2026-03-17
err0
PREAI
errYingjie Yang; Yuxin Zhang; Wenxiang Song; Keyun Zhu; Xinmin Li; Mengyu Tong; Guixia Liu; Weihua Li; Yun Tang
err分享
err收藏
KG-CNNDTI: a knowledge graph-enhanced prediction model for drug-target interactions and application in virtual screening of natural products against Alzheimer’s diseaseKG-CNNDTI：一种基于知识图谱增强的药物-靶点相互作用预测模型及其在针对阿尔茨海默病的天然产物虚拟筛选中的应用
errChinese Journal of Natural Medicines
IF4.9
err2025-11-17
err0
PREAI
errChengyuan Yue; Baiyu Chen; Long Chen; Le Xiong; Changda Gong; Ze Wang; Guixia Liu; Weihua Li; Rui Wang; Yun Tang
err分享
err收藏
Fluor-tools: an integrated platform for dye property prediction and structure optimizationFluor-tools：一个用于染料性质预测和结构优化的集成平台
errDigital Discovery
IF5.6
err2025-11-10
err0
errOAAI
errWenxiang Song; Yuyang Zhang; Le Xiong; Xinmin Li; Jingwei Zhang; Guixia Liu; Weihua Li; Youjun Yang; Yun Tang
err分享
err收藏
Computational Insights into the Regioselective Hydroxylation of Nirmatrelvir Metabolized by Cytochrome P450 3A4
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-11-01
err0
PREAI
errTang, Yan; Fang, Jiaojiao; Liu, Guixia; Tang, Yun; Li, Weihua
err分享
err收藏
Cocrystal Network-Based Recommendation: A Multi-Objective Random Walk-Based Network Model for Virtual Screening of Drug-Drug Cocrystals
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-10-01
err0
PREAI
errSong, Wenxiang; Wu, Juan; Zhou, Changda; Huang, Shengwen; She, Baigen; Liu, Guixia; Li, Weihua; Ren, Guobin; Zhu, Bin; Tang, Yun
err分享
err收藏
CKDTA: A chemical knowledge-enhanced framework for drug–target affinity predictionCKDTA: 一种基于化学知识增强的药物-靶点亲和力预测框架
errJournal of Computational Science
IF3.7
err2025-09-15
err0
PREAI
errXingran Zhao; Yanbu Guo; Bingyi Wang; Weihua Li
err分享
err收藏
Optimization design and experiment of ginger rhizome separation device based on EDEM-RecurDyn software基于EDEM-RecurDyn软件的姜块分离装置优化设计与试验
errSmart Agricultural Technology
IF5.7
err2025-08-27
err0
errOAAI
errWei Li; Weihua Li; Jin Cheng; Rui Hou; Jialin Hou; Yuhua Li
err分享
err收藏
MMPK: A Multimodal Deep Learning Framework to Predict Human Oral Pharmacokinetic ParametersMMPK：一种用于预测人类口服药代动力学参数的多模态深度学习框架
errJournal of Medicinal Chemistry
IF6.8
err2025-07-31
err0
PREAI
errXiang Li; Meiling Zhan; Jiaojiao Fang; Guixia Liu; Yun Tang; Weihua Li
err分享
err收藏
CLaSP: A Contrastive Learning-Guided Latent Scoring Platform for Comprehensive Drug-Likeness EvaluationCLaSP：一种基于对比学习引导的潜在评分平台，用于全面的药物相似性评估
errJournal of Medicinal Chemistry
IF6.8
err2025-07-27
err0
PREAI
errXinmin Li; Long Chen; Hongbo Yu; Le Xiong; Wenxiang Song; Xiang Li; Guixia Liu; Weihua Li; Yun Tang
err分享
err收藏
ERRα-Predictor: A Framework of Ensemble Models for Prediction of ERRα Binders; Antagonists; and Agonists Using Artificial IntelligenceERRα-Predictor：基于人工智能的集成模型框架，用于预测ERRα结合物、拮抗剂和激动剂；
errJournal of Chemical Information and Modeling
IF5.3
err2025-07-01
err0
PREAI
errLe Xiong; Jiahao Xu; Hongbo Yu; Weihua Li; Xinmin Li; Wenxiang Song; Jingwei Zhang; Yun Tang; Guixia Liu
err分享
err收藏
ClaDREB14 enhances the salt tolerance of watermelon by positively regulating the expression of ClaPOD6元, G.; 何, Y.; 孙, D.; 石, M.; 李, W.; 张, J.; 朱, Y. ClaDREB14 通过正向调控 ClaPOD6 的表达来增强西瓜的盐胁迫耐受性。Hortic. Plant J. 2025. [Google Scholar] [CrossRef]
errHorticultural Plant Journal
IF6.2
err2025-05-15
err0
errOAAI
errGaopeng Yuan; Ying He; Dexi Sun; Mingkun Shi; Weihua Li; Jingyu Zhang; Yingchun Zhu
err分享
err收藏
TCnet: A Novel Strategy to Predict Target Combination of Alzheimer's Disease via Network-Based MethodsTCnet: 一种基于网络方法预测阿尔茨海默病靶点组合的新策略
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-04-02
err0
PREAI
errYue, Chengyuan; Chen, Baiyu; Pan, Fei; Wang, Ze; Yu, Hongbo; Liu, Guixia; Li, Weihua; Wang, Rui; Tang, Yun
err分享
err收藏
Cocry-pred: A Dynamic Resource Propagation Method for Cocrystal Prediction
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-03-01
err0
PREAI
errSong, Wenxiang; Peng, Ren; Yu, Hongbo; Zhan, Meiling; Liu, Guixia; Li, Weihua; Ren, Guobin; Zhu, Bin; Tang, Yun
err分享
err收藏
Fluor-Predictor: An Interpretable Tool for Multiproperty Prediction and Retrieval of Fluorescent Dyes
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-03-01
err0
PREAI
errSong, Wenxiang; Xiong, Le; Li, Xinmin; Zhang, Yuyang; Wang, Binya; Liu, Guixia; Li, Weihua; Yang, Youjun; Tang, Yun
err分享
err收藏
Computational Insights into the Interactions of Farnesoid X Receptor with Fargesone A, a Natural Product from Magnolia fargesii
errCHEMICAL RESEARCH IN CHINESE UNIVERSITIES
IF3
err2025-01-03
err0
PREAI
errZhang, Li; Chen, Yaqiong; Li, Weihua
err分享
err收藏
Prediction of Cytochrome P450 Substrates Using the Explainable Multitask Deep Learning Models
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2024-08-28
err1
PREAI
errFang, Jiaojiao; Tang, Yan; Gong, Changda; Huang, Zejun; Feng, Yanjun; Liu, Guixia; Tang, Yun; Li, Weihua
err分享
err收藏

研究方向

蛋白质/酶的计算模拟和药物设计人工智能方法在药物发现和设计中的应用人工智能药物设计蛋白质/酶计算模拟药物代谢化合物ADMET性质预测核受体药物发现作为项目骨干参与国家重点研发计划课题和新药创制重大专项课题【近期主要论文】药物内在清除率预测分子指纹与图表示学习框架多任务模型P450诱导剂预测正-无标签学习CypGEM图变换模型预测细胞色素P450介导的代谢位点药代动力学参数预测多保真深度学习框架UDP-葡萄糖醛酸转移酶介导的药物代谢预测Multimodal deep learning frameworkPrediction of oral pharmacokinetic parameters子图增强扩散模型基于结构的三维分子生成CYP3A4配体结合位点分子动力学模拟溶剂探针细胞色素P450底物预测可解释多任务深度学习模型CYP3A4底物代谢位点预测分子对接Machine learningcytochrome P450 inhibitorscytochrome P450 substrates肝脏微粒体稳定性预测机器学习预测CYP2C8抑制CYP2C9 structural modelssite of metabolism prediction咪达唑仑代谢的同源协同作用细胞色素P450 3A4计算研究细胞色素P450 2B4结构塑性与动力学法尼醇X受体变构激活机制计算化学更多论文
合作学者
合作期刊
M
Michael Karin
H 指数: 254 · 论文数: 904
刘泓 封面图
刘泓 (Hong Liu)
H 指数: 135 · 论文数: 2.8K
X
Xuetao Cao
H 指数: 118 · 论文数: 849
李
李兰娟 (Lanjuan Li)
H 指数: 118 · 论文数: 1.2K
王
王锐 (Rui Wang)
H 指数: 117 · 论文数: 2.1K
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