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周

周如鸿 (Ruhong Zhou)

cancer center

86H指数
642论文数
3.2W被引数
收录论文 282
发表时间
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Targeted degradation of P-TEFb via MDM2 substrate substitution collapses oncogenic transcriptional programs in MDM2-amplified cancers通过MDM2底物替代靶向降解P-TEFb可破坏MDM2扩增癌中的致癌转录程序
errCell Death & Disease
IF9.6
err2026-08-01
err0
errOAAI
errYe Chen; Long Xie; Xian Guan; Xingze Huang; Jiangyu Liu; Zhipeng Zhu; Yuanfang Wu; Hanjun Guo; Lin Ma; Ying Zhang; Jiawei Zhou; Suya Zheng; Ruhong Zhou; Xin Han; Liang Xu
err分享
err收藏
Artificial Avidity Optimization of T-cell Receptors by Integrating Deep Learning Model and Mammalian Cell Surface Display通过整合深度学习模型和哺乳动物细胞表面展示优化T细胞受体的人工亲合力
errPhenomics
IF6.2
err2026-06-17
err0
PREAI
errMengmeng Wei; Shengzuo Bai; Wenfan Chen; Jingcheng Wu; Yi Pan; Wenyi Zhao; Wenhui Qian; Ji Cao; Gang Pan; Xueli Bai; Ruhong Zhou; Wenbin Zhao; Shuqing Chen; Zhan Zhou
err分享
err收藏
Bile Canalicular Bitter Taste Receptors Inhibit β-Adrenergic Receptor-Induced Lipolysis in Steatotic Hepatocytes胆小管苦味受体抑制β-肾上腺素受体诱导的脂肪变性肝细胞的脂肪分解
errInternational Journal of Molecular Sciences
IF4.9
err2026-04-03
err0
errOAAI
errYan-Bo Xue; Shi-Meng Gong; Yuan-Yuan Peng; Defu Yu; Ruhong Zhou; Liquan Huang
err分享
err收藏
Correction to “Nitroimidazole Containing [68Ga]Ga-IPM-N001 as a New CAIX-Targeting Radionuclide Tracer”对“含有[68Ga]Ga-IPM-N001的硝基咪唑作为新型CAIX靶向放射性核素示踪剂”的更正
errJournal of Medicinal Chemistry
IF6.8
err2026-03-29
err0
PREAI
errXiaoke Niu; Sixuan Cheng; Shengping Zhang; Hui Zhang; Kang Chen; Guanqiao Zhang; Yaqi Fu; Yichen Xu; Jiang-Jiang Tang; Wenhai Huang; Xiaowu Dong; Peichen Pan; Lu Wan; Bo Wang; Ruhong Zhou; Dawei Jiang; Peng Teng
err分享
err收藏
Binding Mode of Dimeric Kindlin-2 to F-Actin: An Integrated Computational and Experimental Study二聚体Kindlin-2与F-肌动蛋白结合模式：一项整合计算与实验的研究
errThe Journal of Physical Chemistry B
IF2.9
err2026-03-04
err0
PREAI
errXiuxiu Wang; Nan Yang; Jie Niu; Chenchen Wu; Shengtang Liu; Feng Wu; Lei Chang; Ruhong Zhou; Xuanyu Meng
err分享
err收藏
PSMA-Targeting Chimeras for Cell-Type-Specific Degradation of Surface Immune Checkpoint Protein PD-L1PSMA靶向嵌合体用于细胞类型特异性降解表面免疫检查点蛋白PD-L1
errJACS Au
IF8.7
err2026-01-09
err0
errOAAI
errYuqing Luo; Xiaoxiao Gong; Keren Peng; Yanqing Yang; Meng Chen; Yu Guo; Kang Chen; Jinming Gao; Xing Su; Jinxin Che; Xiaowu Dong; Jiang-Jiang Tang; Xiaolei Zhang; Peng Teng; Ruhong Zhou
err分享
err收藏
In Silico Optimization of GAD65114-122 Autoantigen for Potential Type 1 Diabetes Antigen-Specific Immunotherapy计算机模拟优化GAD65114-122自身抗原，用于潜在1型糖尿病抗原特异性免疫疗法
errJOURNAL OF PHYSICAL CHEMISTRY B
IF2.9
err2025-12-01
err0
PREAI
errFu, Lei; Chan, Kevin Chun; Zhong, Qinglu; Buratto, Damiano; Wu, Song; Zhou, Ruhong
err分享
err收藏
ANUBI: A Platform for Affinity Optimization of Proteins and Peptides in Drug Design
errJOURNAL OF CHEMICAL THEORY AND COMPUTATION
IF5.5
err2025-12-01
err0
PREAI
errBuratto, Damiano; Wang, Wanding; Zhang, Xinyi; Zhu, Qiujie; Meng, Jia; Rigden, Daniel J.; Zhou, Ruhong; Zonta, Francesco
err分享
err收藏
A skin-permeable polymer for non-invasive transdermal insulin delivery一种用于无创透皮胰岛素递送的皮肤渗透性聚合物
errNature
IF48.5
err2025-11-19
err0
errOAAI
errQiuyu Wei; Zhi He; Zifan Li; Zhuxian Zhou; Ying Piao; Jianxiang Huang; Yu Geng; Runnan Zhang; Yaqi Fu; Jiayi Ye; Yue Yuan; Haoru Zhu; Jiaheng Zeng; Yan Zhang; Quan Zhou; Mingyu Xu; Shiqun Shao; Jianbin Tang; Jiajia Xiang; Rongjun Chen; Ruhong Zhou; Youqing Shen
err分享
err收藏
Hydrophilic metformin and hydrophobic biguanides inhibit mitochondrial complex I by distinct mechanisms亲水性二甲双胍和疏水性双胍类通过不同机制抑制线粒体复合物I
errNature Structural & Molecular Biology
IF10.1
err2025-11-10
err0
PREAI
errZhaoxiang He; Fei Teng; Yanqing Yang; Ruiyang Guo; Mengchen Wu; Fangzhu Han; Hongtao Tian; Jiawei Wang; Yiqi Hu; Yangwei Jiang; Leili Zhang; Chenyang Xu; Fan Yang; Jiancang Zhou; Shan Zhang; James A. Letts; Ruhong Zhou; Long Zhou
err分享
err收藏
Deciphering the molecular mechanism of the bacterial division motor TolQRA解析细菌分裂马达TolQRA的分子机制
errCell Discovery
IF12.5
err2025-11-04
err0
errOAAI
errChongrong Shen; Teng Xie; Yongbo Luo; Fangyuan Zhao; Xin Wang; Zhibo Zhang; Jie Pang; Jierou Zhang; Xintan Dong; Shenghai Chang; Bi-Sen Ding; Binwu Ying; Wei Chi; Zhaoming Su; Ruhong Zhou; Xiaodi Tang; Haohao Dong
err分享
err收藏
Assessing Computational Strategies for the Evaluation of Antibody Binding Affinities
errJOURNAL OF CHEMICAL THEORY AND COMPUTATION
IF5.5
err2025-10-01
err1
PREAI
errAutiero, Ida; Buratto, Damiano; Guo, Fengyi; Wang, Wanding; Biswal, Malay Ranjan; Chan, Kevin C.; Zhou, Ruhong; Zonta, Francesco
err分享
err收藏
Targeting spermine metabolism to overcome immunotherapy resistance in pancreatic cancer靶向精胺代谢以克服胰腺癌免疫治疗耐药性
errNature Communications
IF15.7
err2025-08-22
err0
errOAAI
errHanshen Yang; Xiaozhen Zhang; Sirui Zhang; Yanqing Yang; Yan Chen; Yangwei Jiang; Qingsong Lu; Lingyue Liu; Mengyi Lao; Weiran Du; Kang Sun; Lihong He; Jiatao Shi; Xinyuan Liu; Jinyuan Song; Na Lu; Junming Huang; Jinyan Huang; Ruhong Zhou; Xiongbin Lu; Tingbo Liang; Xueli Bai
err分享
err收藏
Natural killer cell-derived granzyme B as a therapeutic target for alleviating graft injury during liver transplantation自然杀伤细胞衍生的颗粒酶B作为减轻肝移植期间移植物损伤的治疗靶点
errActa Pharmaceutica Sinica B
IF14.6
err2025-08-05
err0
errOAAI
errKai Wang; Zhoucheng Wang; Xin Shao; Lijun Meng; Chuanjun Liu; Nasha Qiu; Wenwen Ge; Yutong Chen; Xiao Tang; Xiaodong Wang; Zhengxing Lian; Ruhong Zhou; Shusen Zheng; Xiaohui Fan; Xiao Xu
err分享
err收藏
In Silico Design of High-Affinity gp100 Antigenic Mimotopes for Targeting Melanoma计算机辅助设计高亲和力gp100抗原模拟物用于靶向黑色素瘤
errThe Journal of Physical Chemistry B
IF0
err2025-07-22
err0
PREAI
errRui Ye; Yuxuan Yang; Kevin C. Chan; Dong Zhang; Ruhong Zhou
err分享
err收藏
Overcoming Radiotherapy Resistance in Chordoma through the Synergistic Action of Selenium-Containing Nanoparticles and THZ1通过含硒纳米颗粒与THZ1的协同作用克服脊索瘤的放射治疗抵抗
errACS Nano
IF16
err2025-07-17
err0
PREAI
errLianxue Zhang; Yun Teng; Hai Yang; Jianxiang Huang; Zhaoqi Shi; Cenhao Wu; Zaixing Yang; Liquan Huang; Jun Zou; Ruhong Zhou
err分享
err收藏
A free energy perturbation-assisted machine learning strategy for mimotope screening in neoantigen-based vaccine design
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2025-07-01
err1
PREAI
errZhong, Qinglu; Chan, Kevin C.; Fu, Lei; Zhou, Ruhong
err分享
err收藏
Recent advances in antibody optimization based on deep learning methods基于深度学习方法的抗体优化研究进展
errJournal of Zhejiang University-SCIENCE B
IF4.9
err2025-06-04
err0
PREAI
errRuofan Jin; Ruhong Zhou; Dong Zhang
err分享
err收藏
Integrating AI for next-generation cancer vaccine design集成AI用于下一代癌症疫苗设计
errScience Bulletin
IF21.1
err2025-04-21
err0
PREAI
errGuanqiao Zhang; Ruhong Zhou
err分享
err收藏
Modulation of Bacterial Iron Homeostasis to Enhance Cuproptosis-like Death for the Treatment of Infected Diabetic Wound通过调控细菌铁稳态增强类铜死亡以治疗感染性糖尿病伤口
errACS NANO
IF16
err2025-04-19
err0
PREAI
errFang, G; Dong, QR; Shen, XM; Ye, R; Chang, YC; Pu, KF; Tao, YJ; Gao, XF; Zhou, RH; Ge, CC
err分享
err收藏

研究方向

计算生物学 · 生物物理学 · 人工智能+
合作学者
合作期刊
D
David Baltimore
H 指数: 209 · 论文数: 1.1K
O
Omar K. Farha
H 指数: 169 · 论文数: 1.2K
B
Bruce D. Walker
H 指数: 160 · 论文数: 946
樊春海 封面图
樊春海 (Chunhai Fan)
H 指数: 148 · 论文数: 1.2K
Y
Yuliang Zhao
H 指数: 143 · 论文数: 766
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