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Ben Shen

University of Florida

69H指数
420论文数
2.2W被引数
收录论文 198
发表时间
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DVD-IgG1 antibody–drug conjugates: Expanding the landscape of targeted cancer therapyDVD-IgG1抗体药物偶联物：拓展靶向癌症治疗领域
errCurrent Opinion in Chemical Biology
IF6.1
err2026-02-23
err0
PREAI
errAlexander F. Kiefer; Andrew D. Steele; Christoph Rader; Ben Shen
err分享
err收藏
Chemical Tagging of N-Alkylamine-Containing Natural Products and Pharmaceuticals through C(sp3)–H Functionalization通过C(sp3)–H官能化对含N-烷基胺结构的天然产物和药物进行化学标记
errJournal of the American Chemical Society
IF15.6
err2025-11-14
err0
PREAI
errYuankai Wang; Cunyuan Zhao; Tenghui Wang; Andrew Steele; Manas Joshi; Soichiro Mori; Abhishek Chatterjee; Ben Shen; Matthew D. Disney; Masayuki Wasa
err分享
err收藏
Discovery of 5-Chlorotryptophan-Containing Antibiotics through Metabologenomics-Assisted High-Throughput Screening
errJACS AU
IF8.7
err2025-11-01
err0
PREAI
errBader, Chantal D.; Masuda, Isao; Nichols, Angela; Kalkreuter, Edward; Yang, Dong; Christian, Thomas; Nakano, Yuko; Hou, Ya-Ming; Shen, Ben
err分享
err收藏
Coenzyme A Tethering Mediates Dehydratase Substrate Promiscuity and Reaction Specificity in Platensimycin; Platencin; and Platensilin Biosynthesis辅酶A连接介导了 Platensimycin、Platencin 和 Platensilin 生物合成中脱氢酶的底物不专一性和反应特异性。
errBiochemistry
IF3
err2025-07-16
err0
PREAI
errLucas L. Fluegel; Andrew D. Steele; Edward Kalkreuter; Chun Gui; Dong Yang; Ben Shen
err分享
err收藏
Second Generation Tiancimycin-Based Antibody–Drug Conjugates Enabled by Highly Efficient Semi-synthetic Approach Specifically Targeting B-Cell Malignancies第二代天西霉素基抗体-药物偶联物，通过高效半合成方法实现，专门靶向B细胞恶性肿瘤
errJACS Au
IF8.7
err2025-07-01
err0
errOAAI
errAlexander F. Kiefer; Pankajavalli Thirugnanasambantham; Yuan Jin; Andrew D. Steele; Dobeen Hwang; Yanlong Jiang; Ajeeth Adhikari; Dong Yang; Jing Chang; Rakeb Tafesse; Christoph Rader; Natarajan Muthusamy; Ben Shen
err分享
err收藏
Bacterial diterpene synthases: New opportunities for mechanistic enzymology and engineered biosynthesis (vol 16, pg 132, 2012)细菌二萜合酶：机制酶学和新陈代谢工程合成的新机遇（vol 16, pg 132, 2012）
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2025-06-01
err0
PREAI
errSmanski, Michael J.; Peterson, Ryan M.; Huang, Sheng-Xiong; Shen, Ben
err分享
err收藏
Thoughts for the future对未来的思考
errNATURE CHEMICAL BIOLOGY
IF13.7
err2024-12-24
err0
PREAI
errAlkhalaf, Lona M.; Arrowsmith, Cheryl; Balskus, Emily P.; Bergamini, Giovanna; Bhandari, Rashna; Chang, Christopher J.; Chen, Peng; Chen, Xing; Ciulli, Alessio; Cricco, Julia A.; Davis, Benjamin G.; Delbianco, Martina; Dudareva, Natalia; Dueber, Erin; Ferguson, Fleur; de Giuseppe, Priscila Oliveira; Hamachi, Itaru; Hammond, Ming Chen; Hatzios, Stavroula K.; Do Heo, Won; Janet, Jon Paul; Kamat, Siddhesh S.; Knapp, Stefan; Krishnan, Yamuna; Lang, Kathrin; Laraia, Luca; Leveson-Gower, Reuben B.; Li, Xiang David; Liu, David R.; Liu, Mo-Fang; London, Nir; Mahanta, Nilkamal; Mayor-Ruiz, Cristina; Muir, Tom; Murakami, Mario Tyago; Rhee, Hyun-Woo; Robers, Matt; Satz, Alex; Schulman, Brenda A.; Shen, Ben; Shoichet, Brian; Strauss, Erick; Suzuki, Tsutomu; Tiwary, Pratyush; Waldmann, Herbert; Ward, Thomas R.; Weeks, Amy; Weerapana, Eranthie; Winter, Georg
err分享
err收藏
Structural Insights into the Mechanism of a Polyketide Synthase Thiocysteine Lyase Domain
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-11-15
err0
PREAI
errSteele, Andrew D.; Meng, Song; Li, Gengnan; Kalkreuter, Edward; Chang, Changsoo; Shen, Ben
err分享
err收藏
Enediyne natural product biosynthesis unified by a diiodotetrayne intermediate
errNATURE CHEMICAL BIOLOGY
IF13.7
err2024-06-03
err3
PREAI
errGui, Chun; Kalkreuter, Edward; Lauterbach, Lukas; Yang, Dong; Shen, Ben
err分享
err收藏
Biochemical and Structural Studies of the Carminomycin 4-O-Methyltransferase DnrK
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2024-02-27
err0
PREAI
errJalali, Elnaz; Wang, Fengbin; Overbay, Brooke R.; Miller, Mitchell D.; Shaaban, Khaled A.; Ponomareva, Larissa V.; Ye, Qing; Saghaeiannejad-Esfahani, Hoda; Bhardwaj, Minakshi; Steele, Andrew D.; Teijaro, Christiana N.; Shen, Ben; Van Lanen, Steven G.; She, Qing-Bai; Voss, S. Randal; Phillips Jr, George N.; Thorson, Jon S.
err分享
err收藏
Development of platensimycin, platencin, and platensilin overproducers by biosynthetic pathway engineering and fermentation medium optimization
errJOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
IF3.2
err2024-01-23
err0
errOAAI
errFluegel, Lucas L.; Deng, Ming-Rong; Su, Ping; Kalkreuter, Edward; Yang, Dong; Rudolf, Jeffrey D.; Dong, Liao-Bin; Shen, Ben
err分享
err收藏
Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis
errNATURE CHEMICAL BIOLOGY
IF13.7
err2023-11-09
err6
PREAI
errGui, Chun; Kalkreuter, Edward; Liu, Yu-Chen; Li, Gengnan; Steele, Andrew D.; Yang, Dong; Chang, Changsoo; Shen, Ben
err分享
err收藏
Transcriptional control of carbohydrate catabolism by the CcpA protein in the ruminal bacterium Streptococcus bovis瘤胃细菌牛链球菌中CcpA蛋白对碳水化合物分解代谢的转录控制
errAPPLIED AND ENVIRONMENTAL MICROBIOLOGY
IF3.7
err2023-10-31
err1
errOAAI
errZhao, Xiujuan; Zhang, Ying; He, Banglin; Han, Yu; Shen, Ben; Zang, Yu; Wang, Hongrong
err分享
err收藏
Discovery and biosynthetic pathway analysis of cyclopentane-β-lactone globilactone A
errNATURE SYNTHESIS
IF20
err2023-10-23
err3
PREAI
errXu, Zi Fei; Zhou, Ye Lei; Bo, Sheng Tao; Zhang, Shou Qi; Shi, Jing; Xiang, Lang; Xi, Meng Yu; Zhang, Bo; Xu, Zheng Ren; Yang, Dong; Shen, Ben; Tan, Ren Xiang; Ge, Hui Ming
err分享
err收藏
The many facets of sulfur incorporation in natural product biosynthesis
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2023-10-01
err6
errOAAI
errSteele, Andrew D.; Kiefer, Alexander F.; Shen, Ben
err分享
err收藏
Interplay of emerging and established technologies drives innovation in natural product antibiotic discovery
errCURRENT OPINION IN MICROBIOLOGY
IF7.5
err2023-10-01
err4
PREAI
errBader, Chantal D.; Nichols, Angela L.; Yang, Dong; Shen, Ben
err分享
err收藏
A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-02-21
err9
errOAAI
errBhardwaj, Minakshi; Cui, Zheng; Hankore, Erome Daniel; Moonschi, Faruk H.; Esfahani, Hoda Saghaeiannejad; Kalkreuter, Edward; Gui, Chun; Yang, Dong; Phillips Jr, George N.; Thorson, Jon S.; Shen, Ben; Van Lanena, Steven G.
err分享
err收藏
Neogrisemycin, a Trisulfide-Bridged Angucycline, Produced upon Expressing the Thioangucycline Biosynthetic Gene Cluster in Streptomyces albus J1074
errORGANIC LETTERS
IF5
err2023-02-03
err5
errOAAI
errCao, Mingming; Yang, Dong; Adhikari, Ajeeth; Ye, Fei; Zheng, Chengjian; Yan, Wei; Meng, Song; Su, Ping; Shen, Ben
err分享
err收藏
Application of a Biocatalytic Strategy for the Preparation of Tiancimycin-Based Antibody-Drug Conjugates Revealing Key Insights into Structure-Activity Relationships
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-01-04
err3
PREAI
errSteele, Andrew D.; Kiefer, Alexander F.; Hwang, Dobeen; Yang, Dong; Teijaro, Christiana N.; Adhikari, Ajeeth; Rader, Christoph; Shen, Ben
err分享
err收藏
Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2022-10-24
err12
errOAAI
errGui, Chun; Kalkreuter, Edward; Liu, Yu-Chen; Adhikari, Ajeeth; Teijaro, Christiana N.; Yang, Dong; Chang, Changsoo; Shen, Ben
err分享
err收藏

研究方向

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合作学者
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