logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
C

Charlotte M. Deane

university of oxford

63H指数
508论文数
1.7W被引数
收录论文 143
发表时间
logo
Structural T-Cell Receptor Analysis in the Age of Machine Learning机器学习时代的结构T细胞受体分析
errImmunological Reviews
IF8.3
err2026-09-06
err0
errOAAI
errNele P. Quast; Matthew I. J. Raybould; Charlotte M. Deane
err分享
err收藏
iNOS modulates inflammatory responses in an NO-independent manner through direct interaction with IRG1 in mitochondria一氧化氮合酶（iNOS）通过直接与线粒体中的干扰素调节基因1（IRG1）相互作用，以非一氧化氮依赖的方式调节炎症反应
errNature Metabolism
IF20.8
err2026-04-10
err0
errOAAI
errMarina Diotallevi; Carlos Outeiral; Priyanka Patel; Gareth S. D. Purvis; Surawee Chuaiphichai; Thomas Nicol; Faseeha Ayaz; Daniel A. Nissley; Ganna O. Krasnoselska; Svenja Hester; John H. McVey; Roman Fischer; Benedikt Kessler; Charlotte M. Deane; Raymond J. Owens; Keith M. Channon; Mark J. Crabtree
err分享
err收藏
Ginkgo Datapoints Antibody Developability Competition outcomes: limited model performance and a call for data standardization银杏数据点抗体可开发性竞赛结果：有限模型性能及对数据标准化的呼吁
errmAbs
IF7.3
err2026-02-22
err0
errOAAI
errLood van Niekerk; Joshua Moller; Seth Ritter; Porfirio Quintero-Cadena; Rich Cohen; Georgia Channing; Michael Chungyuon; Laura Rand; Alexander Smith; Aanal Bhatt; Yolaine Pierre; Blake Harris; Xiang Ao; Lucia Grippo; Maximilian Schwenk; Adam Rosenbaum; Olga Allen; Nimra Asi; Jiang Zhu; Aviral Singh; Daksh Sammi; Rushikesh Jadhav; Antonín Dušek; Shyam Chandra; Valentin Badea; Nels Thorsteinson; Nathaniel Blalock; Jeonghyeon Kim; Oliver M. Turnbull; Ameya Kulkarni; Vivek Kohar; Netsanet Gebremedhin; Charlotte M. Deane; Peter M. Tessier; Ammar Arsiwala
err分享
err收藏
LICHEN enables light-chain immunoglobulin sequence generation conditioned on the heavy chain and experimental needsLICHEN能够在重链和实验需求的基础上生成轻链免疫球蛋白序列。
errCommunications Biology
IF5.1
err2026-02-21
err0
errOAAI
errHenriette L. Capel; Isaac Ellmen; Chris J. Murray; Giulia Mignone; Megan Black; Brendan Clarke; Conor Breen; Sean Tierney; Patrick Dougan; Richard J. Buick; Alexander Greenshields-Watson; Charlotte M. Deane
err分享
err收藏
Characterising nanobody developability to improve therapeutic design using the Therapeutic Nanobody Profiler
errCommunications Biology
IF5.1
err2026-01-31
err0
errOAAI
errGemma L. Gordon; João Gervasio; Colby Souders; Charlotte M. Deane
err分享
err收藏
Assessing the Chemical Intelligence of Large Language Models评估大型语言模型的化学智能
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-12-01
err0
PREAI
errRuncie, Nicholas T.; Deane, Charlotte M.; Imrie, Fergus
err分享
err收藏
Inferring residue level hydrogen deuterium exchange with ReX使用ReX推断残基水平的氢-氘交换
errCommunications Chemistry
IF6.2
err2025-11-10
err0
errOAAI
errOliver M. Crook; Nathan Gittens; Chun-wa Chung; Charlotte M. Deane
err分享
err收藏
Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells正交IMiD-降解基序对诱导细胞中特异性的蛋白质降解
errACS Chemical Biology
IF3.8
err2025-11-02
err0
errOAAI
errPatrick J. Brennan; Rebecca E. Saunders; Mary Spanou; Sarah E. Singleton; Marta Serafini; Liang Sun; Guillaume P. Heger; Agnieszka Konopacka; Ryan D. Beveridge; C. Cameron Taylor; Peter DePaola IV; Laurie Gordon; Shenaz B. Bunally; Aurore Saudemont; Andrew B. Benowitz; Carlos Martinez-Fleites; Danielle L. Schmitt; Robert Damoiseaux; Markus A. Queisser; Heeseon An; Charlotte M. Deane; Michael M. Hann; Lewis L. Brayshaw; Stuart J. Conway
err分享
err收藏
HeavyBuilder: Analysis of High-Throughput of Antibody Heavy Chain Repertoires in the Structural SpaceHeavyBuilder: 抗体重链库在结构空间中的高通量分析
errJournal of Molecular Biology
IF4.5
err2025-10-24
err0
errOAAI
errJoao D. Gervasio; Alexander Greenshields-Watson; Nele Quast; Brennan Abanades; Liza F. Felicori; Charlotte M. Deane
err分享
err收藏
Incorporating targeted protein structure in deep learning methods for molecule generation in computational drug design将靶向蛋白质结构整合到深度学习方法中，用于计算药物设计中的分子生成
errChem. Sci.
IF7.4
err2025-10-20
err0
errOAAI
errLucy Vost; Yael Ziv; Charlotte Mary Deane
err分享
err收藏
Predicting the conformational flexibility of antibody and T cell receptor complementarity-determining regions预测抗体和T细胞受体互补决定区的构象柔性
errNature Machine Intelligence
IF23.9
err2025-10-16
err0
errOAAI
errFabian C. Spoendlin; Monica L. Fernández-Quintero; Sai S. R. Raghavan; Hannah L. Turner; Anant Gharpure; Johannes R. Loeffler; Wing K. Wong; Alexander Bujotzek; Guy Georges; Andrew B. Ward; Charlotte M. Deane
err分享
err收藏
Investigating the volume and diversity of data needed for generalizable antibody–antigen ΔΔG prediction调查可推广的抗体-抗原 Δ Δ g预测所需的数据量和多样性
errNature Computational Science
IF18.3
err2025-07-08
err0
errOAAI
errAlissa M. Hummer; Constantin Schneider; Lewis Chinery; Charlotte M. Deane
err分享
err收藏
Computational design of therapeutic antibodies with improved developability: efficient traversal of binder landscapes and rescue of escape mutations治疗性抗体可开发性的计算设计：结合物景观的高效遍历与逃逸突变的挽救
errmAbs
IF7.3
err2025-06-03
err0
errOAAI
errFrédéric A. Dreyer; Constantin Schneider; Aleksandr Kovaltsuk; Daniel Cutting; Matthew J. Byrne; Daniel A. Nissley; Henry Kenlay; Claire Marks; David Errington; Richard J. Gildea; David Damerell; Pedro Tizei; Wilawan Bunjobpol; John F. Darby; Ieva Drulyte; Daniel L. Hurdiss; Sachin Surade; Newton Wahome; Douglas E.V. Pires; Charlotte M. Deane
err分享
err收藏
T-cell receptor structures and predictive models reveal comparable alpha and beta chain structural diversity despite differing genetic complexity尽管遗传复杂性不同，但T细胞受体结构和预测模型揭示了可比的 α 和 β 链结构多样性
errCOMMUNICATIONS BIOLOGY
IF5.1
err2025-03-04
err0
errOAAI
errQuast, Nele P.; Abanades, Brennan; Guloglu, Bora; Karuppiah, Vijaykumar; Harper, Stephen; Raybould, Matthew I. J.; Deane, Charlotte M.
err分享
err收藏
Narrowing the gap between machine learning scoring functions and free energy perturbation using augmented data使用增强数据缩小机器学习评分函数和自由能扰动之间的差距
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2025-02-08
err0
errOAAI
errValsson, Isak; Warren, Matthew T.; Deane, Charlotte M.; Magarkar, Aniket; Morris, Garrett M.; Biggin, Philip C.
err分享
err收藏
Challenges and compromises: Predicting unbound antibody structures with deep learning
errCURRENT OPINION IN STRUCTURAL BIOLOGY
IF7
err2025-02-01
err0
errOAAI
errGreenshields-Watson, Alexander; Vavourakis, Odysseas; Spoendlin, Fabian C.; Cagiada, Matteo; Deane, Charlotte M.
err分享
err收藏
Fragmenstein: predicting protein-ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding-based methodology
errJOURNAL OF CHEMINFORMATICS
IF5.7
err2025-01-13
err1
errOAAI
errFerla, Matteo P.; Sanchez-Garcia, Ruben; Skyner, Rachael E.; Gahbauer, Stefan; Taylor, Jenny C.; von Delft, Frank; Marsden, Brian D.; Deane, Charlotte M.
err分享
err收藏
The protein universe in 3D
errNATURE CHEMICAL BIOLOGY
IF13.7
err2024-12-24
err0
PREAI
errEllmen, Isaac; Raybould, Matthew I. J.; Deane, Charlotte M.
err分享
err收藏
Quantifying conformational changes in the TCR:pMHC-I binding interface
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-12-02
err1
errOAAI
errMcmaster, Benjamin; Thorpe, Christopher J.; Rossjohn, Jamie; Deane, Charlotte M.; Koohy, Hashem
err分享
err收藏
Humatch - fast, gene-specific joint humanisation of antibody heavy and light chains
errMABS
IF7.3
err2024-11-29
err0
errOAAI
errChinery, Lewis; Jeliazkov, Jeliazko R.; Deane, Charlotte M.
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
C
Carlos Caldas
H 指数: 158 · 论文数: 1.4K
S
Sarah A. Teichmann
H 指数: 141 · 论文数: 677
D
David Eisenberg
H 指数: 139 · 论文数: 744
A
Adrian V. S. Hill
H 指数: 137 · 论文数: 795
C
Carol V. Robinson
H 指数: 132 · 论文数: 818
查看更多