Burgy, Olivier; Mayr, Christoph H.; Schenesse, Deborah; Papakonstantinou, Efthymios Fousekis; Ballester, Beatriz; Sengupta, Arunima; She, Yixin; Hu, Qianjiang; Melo-Narvaez, Maria Camila; Jain, Eshita; Pestoni, Jeanine C.; Mozurak, Molly; Estrada-Bernal, Adriana; Onwuka, Ugochi; Coughlan, Christina; Parimon, Tanyalak; Chen, Peter; Heimerl, Thomas; Bange, Gert; Schmeck, Bernd T.; Lindner, Michael; Hilgendorff, Anne; Ruppert, Clemens; Guenther, Andreas; Mann, Matthias; Yildirim, Ali Oender; Eickelberg, Oliver; Jung, Anna Lena; Schiller, Herbert B.; Lehmann, Mareike; Burgstaller, Gerald; Koenigshoff, Melanie

COPD basal cells are primed towards secretory to multiciliated cell imbalance driving increased resilience to environmental stressors

THORAX

IF7.7

2024-01-291

OAAI

Stoleriu, Mircea Gabriel; Ansari, Meshal; Strunz, Maximilian; Schamberger, Andrea; Heydarian, Motaharehsadat; Ding, Yaobo; Voss, Carola; Schneider, Juliane Josephine; Gerckens, Michael; Burgstaller, Gerald; Castelblanco, Alejandra; Kauke, Teresa; Fertmann, Jan; Schneider, Christian; Behr, Juergen; Lindner, Michael; Stacher-Priehse, Elvira; Irmler, Martin; Beckers, Johannes; Eickelberg, Oliver; Schubert, Benjamin; Hauck, Stefanie M.; Schmid, Otmar; Hatz, Rudolf A.; Stoeger, Tobias; Schiller, Herbert; Hilgendorff, Anne

Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-01-1117

OAAI

Mayr, Christoph H.; Sengupta, Arunima; Asgharpour, Sara; Ansari, Meshal; Pestoni, Jeanine C.; Ogar, Paulina; Angelidis, Ilias; Liontos, Andreas; Rodriguez-Castillo, Jose Alberto; Lang, Niklas J.; Strunz, Maximilian; Porras-Gonzalez, Diana; Gerckens, Michael; De Sadeleer, Laurens J.; Oehrle, Bettina; Viteri-Alvarez, Valeria; Fernandez, Isis E.; Tallquist, Michelle; Irmler, Martin; Beckers, Johannes; Eickelberg, Oliver; Stoleriu, Gabriel Mircea; Behr, Juergen; Kneidinger, Nikolaus; Wuyts, Wim A.; Wasnick, Roxana Maria; Yildirim, Ali Oender; Ahlbrecht, Katrin; Morty, Rory E.; Samakovlis, Christos; Theis, Fabian J.; Burgstaller, Gerald; Schiller, Herbert B.

Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-12-0619

Lang, Niklas J.; Gote-Schniering, Janine; Porras-Gonzalez, Diana; Yang, Lin; De Sadeleer, Laurens J.; Jentzsch, R. Christoph; Shitov, Vladimir A.; Zhou, Shuhong; Ansari, Meshal; Agami, Ahmed; Mayr, Christoph H.; Hooshiar Kashani, Baharak; Chen, Yuexin; Heumos, Lukas; Pestoni, Jeanine C.; Molnar, Eszter Sarolta; Geeraerts, Emiel; Anquetil, Vincent; Saniere, Laurent; Woegrath, Melanie; Gerckens, Michael; Lehmann, Mareike; Yildirim, Ali Onder; Hatz, Rudolf; Kneidinger, Nikolaus; Behr, Juergen; Wuyts, Wim A.; Stoleriu, Mircea-Gabriel; Luecken, Malte D.; Theis, Fabian J.; Burgstaller, Gerald; Schiller, Herbert B.

Machine-learning based BAL cytology of lung transplant patients

EUROPEAN RESPIRATORY JOURNAL

IF21

2023-10-270

PRE

Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multi-lineage cell circuit dynamics in human lung fibrogenesis

EUROPEAN RESPIRATORY JOURNAL

IF21

2023-10-271

Lang, Niklas Jonathan; Gote-Schniering, Janine; Porras-Gonzalez, Diana; Yang, Lin; De Sadeleer, Laurens J.; Jentzsch, R. Christoph; Shitov, Vladimir A.; Zhou, Shuhong; Ansari, Meshal; Agami, Ahmed; Mayr, Christoph H.; Kashani, Baharak Hooshiar; Chen, Yuexin; Heumos, Lukas; Pestoni, Jeanine C.; Geeraerts, Emil; Anquetil, Vincent; Saniere, Laurent; Woegrath, Melanie; Gerckens, Michael; Hatz, Rudolf; Kneidinger, Nikolaus; Behr, Juergen; Wuyts, Wim A.; Stoleriu, Mircea-Gabriel; Luecken, Malte D.; Theis, Fabian J.; Burgstaller, Gerald; Schiller, Herbert. B.

Functional profiling of primary human fibroblasts derived from healthy and diseased lung tissue

EUROPEAN RESPIRATORY JOURNAL

IF21

2023-10-270

PRE

Cytokine signaling converging on IL11 in ILD fibroblasts provokes aberrant epithelial differentiation signatures

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-05-177

OAAI

The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD

NATURE COMMUNICATIONS

IF15.7

2022-03-1453

OAAI

Guensel, Gizem Guenes; Conlon, Thomas M.; Jeridi, Aicha; Kim, Rinho; Ertuez, Zeynep; Lang, Niklas J.; Ansari, Meshal; Novikova, Mariia; Jiang, Dongsheng; Strunz, Maximilian; Gaianova, Mariia; Hollauer, Christine; Gabriel, Christina; Angelidis, Ilias; Doll, Sebastian; Pestoni, Jeanine C.; Edelmann, Stephanie L.; Kohlhepp, Marlene Sophia; Guillot, Adrien; Bassler, Kevin; Van Eeckhoutte, Hannelore P.; Kayalar, Oezgecan; Konyalilar, Nur; Kanashova, Tamara; Rodius, Sophie; Ballester-Lopez, Carolina; Robles, Carlos M. Genes; Smirnova, Natalia; Rehberg, Markus; Agarwal, Charu; Krikki, Ioanna; Piavaux, Benoit; Verleden, Stijn E.; Vanaudenaerde, Bart; Koenigshoff, Melanie; Dittmar, Gunnar; Bracke, Ken R.; Schultze, Joachim L.; Watz, Henrik; Eickelberg, Oliver; Stoeger, Tobias; Burgstaller, Gerald; Tacke, Frank; Heissmeyer, Vigo; Rinkevich, Yuval; Bayram, Hasan; Schiller, Herbert B.; Conrad, Marcus; Schneider, Robert; Yildirim, Ali Oender

Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics

SCIENCE ADVANCES

IF12.5

2021-12-2412

OAAI

Gerckens, Michael; Schorpp, Kenji; Pelizza, Francesco; Woegrath, Melanie; Reichau, Kora; Ma, Huilong; Dworsky, Armando-Marco; Sengupta, Arunima; Stoleriu, Mircea Gabriel; Heinzelmann, Katharina; Merl-Pham, Juliane; Irmler, Martin; Alsafadi, Hani N.; Trenkenschuh, Eduard; Sarnova, Lenka; Jirouskova, Marketa; Friess, Wolfgang; Hauck, Stefanie M.; Beckers, Johannes; Kneidinger, Nikolaus; Behr, Juergen; Hilgendorff, Anne; Hadian, Kamyar; Lindner, Michael; Koenigshoff, Melanie; Eickelberg, Oliver; Gregor, Martin; Plettenburg, Oliver; Yildirim, Ali Oender; Burgstaller, Gerald

Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread

NUCLEIC ACIDS RESEARCH

IF13.1

2021-12-2044

OAAI

Epigenetic regulation via PRMT7 controls monocyte migration and COPD pathogenesis

EUROPEAN RESPIRATORY JOURNAL

IF21

2021-11-250

PRE

Transcriptomic landscape of radiation-induced murine thyroid proliferative lesions

辐射诱导的鼠甲状腺增生性病变的转录组景观