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J

José de León

Eastern State Hospital

78H指数
628论文数
2.2W被引数
收录论文 236
发表时间
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Reply to “Beyond Hypersalivation: Protecting Older Clozapine Users through Better Recognition of Swallowing Vulnerability”回复“超越流涎：通过更好地识别吞咽易损性来保护老年氯氮平使用者”
errAmerican Journal of Geriatric Psychiatry
IF3.8
err2026-08-13
err0
PREAI
errJose de Leon; Emilio J. Sanz; Carlos De las Cuevas
err分享
err收藏
A critical review of the early clozapine trials published in German and a discussion of the many unresolved issues left by these trials对发表在德语的早期氯氮平试验的批判性综述以及对这些试验留下的许多悬而未决问题的讨论
errNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
IF3.1
err2026-08-01
err0
errOAAI
errStefano Ferrea; Jose de Leon; Pierre Baumann; Otto Benkert; Hanfried Helmchen; Christoph U. Correll; Georgios Schoretsanitis
err分享
err收藏
VigiBase suggests that the number of deaths by suicide in adolescents with schizophrenia as a result of not taking clozapine may be much higher than the number of deaths from agranulocytosis after taking clozapineVigiBase表明，未使用氯氮平治疗的青少年精神分裂症患者自杀死亡人数可能远高于使用氯氮平后发生粒细胞缺乏症导致的死亡人数
errEUROPEAN CHILD & ADOLESCENT PSYCHIATRY
IF4.9
err2026-07-29
err0
PREAI
errSara Jiménez-Fernández; Carlos De Las Cuevas; Emilio J. Sanz; Carmen Moreno; Celso Arango; Jose de Leon
err分享
err收藏
Are the 8 Finnish Deaths Explained by Agranulocytosis More Important than the Thousands of Suicide Deaths Associated with the Lack of Use of Clozapine? Reflections on Clozaphobia芬兰因粒细胞缺乏症导致的8例死亡是否比因未使用氯氮平而导致的数千例自杀死亡更为重要？对“氯氮平恐惧症”的思考
errJournal of Clinical Psychopharmacology
IF2.8
err2026-07-06
err0
PREAI
errde Leon, Jose MD
err分享
err收藏
Reply to beyond fatality signals: reconsidering clozapine safety through severe gastrointestinal hypomotility and real-world clinical complexity超越致死信号：通过严重胃肠道低动力和真实世界临床复杂性重新审视氯氮平的安全性
errAsian Journal of Psychiatry
IF4.5
err2026-06-18
err0
PREAI
errJose de Leon; Emilio J. Sanz; Carlos De las Cuevas
err分享
err收藏
Multidisciplinary consensus on prevention; screening and monitoring of clozapine-associated myocarditis and clozapine rechallenge after myocarditis: commentary; de Leon多学科共识：预防、筛查和监测氯氮平相关性心肌炎及心肌炎后氯氮平再挑战：评论；de Leon
errThe British Journal of Psychiatry
IF0
err2026-03-18
err0
PREAI
errJose de Leon
err分享
err收藏
Using Pharmacological Knowledge to Provide Safety Suggestions During Involuntary Clozapine Treatment利用药理学知识为氯氮平强制治疗期间提供安全建议
errActa Psychiatrica Scandinavica
IF5
err2026-03-09
err0
PREAI
errJose de Leon
err分享
err收藏
An update on the pharmacokinetic and pharmacodynamic interactions between antidepressants and antiseizure medications抗抑郁药与抗癫痫药物之间的药代动力学和药效动力学相互作用研究进展
errExpert Opinion on Drug Metabolism & Toxicology
IF3.4
err2026-03-01
err0
PREAI
errSpina, Edoardo; Barbieri, Maria Antonietta; Alborghetti, Marika; Nicoletti, Ferdinando; de Leon, Jose
err分享
err收藏
Prescribing clozapine to 10% of patients with schizophrenia may save 320,000 lives and cost 2400 deaths from agranulocytosis为10%的精神分裂症患者开具氯氮平处方可能挽救32万条生命，并导致2,400例由粒细胞缺乏症引起的死亡。
errEuropean Neuropsychopharmacology
IF6.7
err2025-12-23
err0
PREAI
errJose de Leon
err分享
err收藏
Clozapine and Suicide in VigiBase: Most Important Fatal Outcome in Young Males and Differences Between Attempted and Completed Suicide氯氮平与自杀在VigiBase中：年轻男性中最主要的致命结局以及尝试自杀与完成自杀之间的差异
errJournal of Clinical Psychopharmacology
IF2.8
err2025-12-01
err0
PREAI
errde Leon, Jose MD; de Leon, Victoria C. MD, MSc; Sanz, Emilio J. MD, PhD; De las Cuevas, Carlos MD
err分享
err收藏
Fatal Outcomes in Use of Clozapine: A VigiBase Study of 6402 Women and 11,222 Men氯氮平使用中的死亡结局：一项基于VigiBase的研究，涉及6402名女性和11,222名男性
errJournal of Clinical Psychopharmacology
IF2.8
err2025-10-15
err0
PREAI
errDe Las Cuevas, Carlos PhD, MD; Sanz, Emilio J. MD, PhD; de Leon, Jose MD
err分享
err收藏
Establishing a Cardiac Implantable Electronic Device Lead Extraction Program in a Resource-Limited Setting在资源有限环境下建立心脏植入式电子设备导线移除程序
errJOURNAL OF ARRHYTHMIA
IF1.7
err2025-10-01
err1
errOAAI
errGervacio, Giselle G.; De Leon, Jhobeleen D.; Agbayani, Michael Joseph C.; Cheng-Bromeo, Paula Victoria; Aya-ay, Tam Adrian P.; Rangiris, Jonaiha G.; Nicolas, Richard S.; Punzalan, Felix Eduardo R.; Anonuevo, John C.
err分享
err收藏
Benzodiazepines and clozapine co-prescription in clinical practice: a systematic review and expert recommendations苯二氮䓬类药物与氯氮平联合处方在临床实践中的应用：系统评价与专家建议
errExpert Opinion on Drug Metabolism & Toxicology
IF3.4
err2025-08-20
err0
PREAI
errClélia Quiles; Jose de Leon; Hélène Verdoux
err分享
err收藏
Clozapine for older adults with severe mental illness: a systematic review and expert recommendations for clinical practice氯氮平用于严重精神疾病老年患者：一项系统综述及临床实践专家建议
errExpert Review of Clinical Pharmacology
IF3
err2025-07-10
err0
PREAI
errHélène Verdoux; Alexis Lepetit; Jose de Leon
err分享
err收藏
The clozapine package inserts need to reflect lower doses for Asians氯氮平的药品说明书需要反映亚洲人较低的剂量。
errAsian Journal of Psychiatry
IF4.5
err2025-07-08
err0
PREAI
errJose de Leon; Rajiv Tandon
err分享
err收藏
Interindividual variability in olanzapine steady-state concentrations in Chinese: exploring single nucleotide polymorphisms of metabolic enzymes中国人群中奥氮平稳态浓度的个体间差异：探讨代谢酶的单核苷酸多态性
errBritish Journal of Clinical Pharmacology
IF3
err2025-07-08
err0
PREAI
errZhou Wan; Yan-Nan Zang; Fei Jia; Qi Yang; Wen-Wei Chen; Chen-Geng Liu; Xin-Gang Li; Jose de Leon; Can-Jun Ruan
err分享
err收藏
Clozapine-treated patients and myocardial infarction in adults: a pharmacovigilance study in VigiBase interpreted in the context of the literature氯氮平治疗患者与成人心肌梗死：一项在VigiBase中进行的药物警戒研究，并结合文献进行解读
errExpert Opinion on Drug Safety
IF3.1
err2025-06-13
err0
PREAI
errCarlos De las Cuevas; Emilio J. Sanz; Jose de Leon
err分享
err收藏
The Relevance of Pharmacokinetic Biomarkers in Response to Methadone Treatment: A Systematic Review美沙酮治疗反应中药物动力学生物标志物的相关性：一项系统综述
errPHARMACEUTICALS
IF4.8
err2025-04-25
err0
errOAAI
errRecarey-Rama, Sheila; Gomez-Trigo, Jesus; Gil-Rodriguez, Almudena; Dominguez, Eduardo; Sanchez-Martinez, Ines; Riveiro-Recimil, Angela; Barral-Rana, Alba; de Leon, Jose; Rodriguez-Viyuela, Ana; Arrojo, Manuel; Carracedo, Angel; Maronas, Olalla
err分享
err收藏
Evaluating the adverse drug reactions to clozapine in populations of children and adolescents: insights from VigiBase data评估儿童和青少年人群对氯氮平的药物不良反应: 来自VigiBase数据的见解
errEUROPEAN CHILD & ADOLESCENT PSYCHIATRY
IF4.9
err2024-12-02
err0
PREAI
errde las Cuevas, Carlos; Sanz, Emilio J.; Jimenez-Fernandez, Sara; Schoretsanitis, Georgios; Ruan, Can-Jun; de Leon, Jose
err分享
err收藏
Clozapine for persons with neurodevelopmental disorders: a systematic review and expert recommendations for clinical practice
errEXPERT REVIEW OF CLINICAL PHARMACOLOGY
IF3
err2024-10-03
err2
PREAI
errVerdoux, Helene; Quiles, Clelia; de Leon, Jose
err分享
err收藏

研究方向

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合作学者
合作期刊
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