Preclinical Investigation of a Lipoglycopeptide Dry Powder Inhalation Therapy for the Treatment of Pulmonary MRSA InfectionPHARMACEUTICSIF5.52023-08-310OAAI
Effect of Inhalation Profile on Delivery of Treprostinil Palmitil Inhalation PowderPHARMACEUTICSIF5.52023-03-142OAAI
Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial HypertensionJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICSIF3.82022-10-013OAAI
Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertensionEUROPEAN JOURNAL OF PHARMACOLOGYIF4.72022-02-016OAAI
Treprostinil palmitil, an inhaled long-acting pulmonary vasodilator, does not show tachyphylaxis with daily dosing in ratsPULMONARY PHARMACOLOGY & THERAPEUTICSIF2.82021-02-013OAAI
Comparison of Treprostinil Palmitil Inhalation Suspension (TPIS) or Oral Sildenafil (Sild) in a Sugen/Hypoxia Rat Model of PAHEUROPEAN RESPIRATORY JOURNALIF212020-10-280PRE
No evidence of desensitization to repeat dosing with treprostinil palmitil inhalation suspension (TPIS) for 32-consecutive days in hypoxia-challenged telemetered ratsEUROPEAN RESPIRATORY JOURNALIF212020-10-280PRE
Cough and airway irritation with inhaled treprostinil does not involve activation of laryngeal reflexes.EUROPEAN RESPIRATORY JOURNALIF212018-11-192PRE
Inhaled hexadecyl-treprostinil provides pulmonary vasodilator activity at significantly lower plasma concentrations than infused treprostinilPULMONARY PHARMACOLOGY & THERAPEUTICSIF2.82018-04-0118OAAI
Inhalation of dry powder INS1009 (DP-INS1009) does not activate the cough reflex in guinea pigs: a comparison with nebulized treprostinilEUROPEAN RESPIRATORY JOURNALIF212017-12-061PRE
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