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G

Gregory L. Challis

monash university

58H指数
216论文数
2.0W被引数
收录论文 103
发表时间
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A bacterial metabolite rewires fungal metabolism, triggering the hyphae-to-yeast transition细菌代谢物重编程真菌代谢，引发菌丝到酵母的转换
errCurrent Biology
IF7.5
err2026-08-19
err0
errOAAI
errManasa Bharathwaj; Vinzenz Hofferek; Angavai Swaminathan; Rachael Turner; Françios A.B. Olivier; Maalavikha Prabhakaran; Yu Zhang; Malcolm J. McConville; Gregory L. Challis; Traude H. Beilharz; Ana Traven
err分享
err收藏
Molecular basis for depsipeptide HDAC inhibitor combinatorial biosynthesisdepsipeptide HDAC 抑制剂组合生物合成的分子基础
errNature Communications
IF15.7
err2026-07-01
err0
errOAAI
errMunro Passmore; Xinyun Jian; Xinyi Zhao; Emmanuel L. C. de los Santos; Douglas M. Roberts; Józef R. Lewandowski; Matthew Jenner; Lona M. Alkhalaf; Gregory L. Challis
err分享
err收藏
Substrate Scope and Catalytic Mechanism of α; β-Epoxyketone Synthase EpnF Illuminated by In Situ Esterase-Mediated Deprotection底物范围和α;β-环氧酮合成酶EpnF的催化机制由原位酯酶介导的去保护作用阐明
errACS Catalysis
IF13.1
err2026-06-25
err0
errOAAI
errCallum J. Bullock; Marlene L. Rothe; Joshua W. Cartwright; Munro Passmore; Alex J. Mullins; Fabrizio Alberti; Józef R. Lewandowski; Lona M. Alkhalaf; Gregory L. Challis
err分享
err收藏
PARAS: High-Accuracy Machine Learning of Substrate Specificities in Nonribosomal Peptide SynthetasesPARAS：非核糖体肽合成酶底物特异性的高精度机器学习
errJACS Au
IF8.7
err2026-04-10
err0
errOAAI
errBarbara R. Terlouw; Chuan Huang; David Meijer; José D. D. Cediel-Becerra; Ruolin He; Marlene L. Rothe; Matthew Jenner; Shanshan Zhou; Yu Zhang; Christopher D. Fage; Yuta Tsunematsu; Gilles P. van Wezel; Serina L. Robinson; Fabrizio Alberti; Lona M. Alkhalaf; Marc G. Chevrette; Gregory L. Challis; Marnix H. Medema
err分享
err收藏
Total Synthesis of iso-Gladiolin Methyl Ester (Lagriene Methyl Ester) via Catalytic Asymmetric C–C Coupling of Alcohols通过醇的不对称c-c偶联催化合成异-Gladiolin甲酯 (Lagriene甲酯)
errJournal of the American Chemical Society
IF15.6
err2026-02-18
err0
PREAI
errKatherine L. Verboom; Yoon Cho; James A. Duncan; Yu Zhang; Lona M. Alkhalaf; Gregory L. Challis; Michael J. Krische
err分享
err收藏
Trifunctional flavoenzyme-catalyzed asymmetric 4-alkyl-butenolide assembly in avenolide biosynthesisavenolide生物合成中的三功能黄素酶催化的不对称4-烷基-丁烯内酯组装
errNature Communications
IF15.7
err2026-02-07
err0
errOAAI
errWenrui Li; Jinlian Zhao; Weibo Zeng; Ruifei Zhang; Lei Yan; Yuting Fan; Jiaxin Liu; Wenzhao Wang; Gregory L. Challis; Shanshan Zhou
err分享
err收藏
Discovery of Late Intermediates in Methylenomycin Biosynthesis Active against Drug-Resistant Gram-Positive Bacterial Pathogens在甲烯基霉素生物合成中发现针对耐药革兰氏阳性细菌病原体的晚期中间体
errJournal of the American Chemical Society
IF15.6
err2025-10-27
err0
errOAAI
errChristophe Corre; Gideon A. Idowu; Lijiang Song; Melanie E. Whitehead; Lona M. Alkhalaf; Gregory L. Challis
err分享
err收藏
Phosphine-Mediated (3 + 2) Cycloaddition of Electron-Poor Terminal Alkynes: A Concise Route to Premethylenomycin C Lactone膦促进的缺电子端基炔(3+2)环加成反应：合成普甲烯霉素C内酯的一种简洁路线
errThe Journal of Organic Chemistry
IF0
err2025-07-29
err0
PREAI
errAlexander I. Wright; Chenxi Zhang; Jing Cao; Yuji Nakano; Lucia Sánchez-Jiménez; Julia DeBono; Sankeert Kapatkar; Gregory L. Challis; David W. Lupton
err分享
err收藏
Teicoplanin Nonribosomal Peptide Synthetase Is Unable to Incorporate Alpha-Ketoacid Building Blocks替考拉宁非核糖体肽合成酶无法整合α-酮酸砌块
errBIOCHEMISTRY
IF3
err2025-04-11
err0
PREAI
errRatnayake, Minuri S.; Jian, Xinyun; Tailhades, Julien; Challis, Gregory L.; Hansen, Mathias H.; Lewandowski, Jozef R.; Cryle, Max J.
err分享
err收藏
Mode of Action and Mechanisms of Resistance to the Unusual Polyglycosylated Thiopeptide Antibiotic Persiathiacin A
errACS INFECTIOUS DISEASES
IF3.8
err2024-12-09
err0
PREAI
errWoodgate, Jason; Sumang, Felaine A.; Salliss, Mary E.; Belousoff, Matthew; Ward, Alan C.; Challis, Gregory L.; Zenkin, Nikolay; Errington, Jeff; Dashti, Yousef
err分享
err收藏
Molecular Basis for Short-Chain Thioester Hydrolysis by Acyl Hydrolases in trans-Acyltransferase Polyketide Synthases
errJACS AU
IF8.7
err2024-11-18
err1
errOAAI
errFage, Christopher D.; Passmore, Munro; Tatman, Ben P.; Smith, Helen G.; Jian, Xinyun; Dissanayake, Upeksha C.; Foran, Mia E.; Cisneros, G. Andres; Challis, Gregory L.; Lewandowski, Jozef R.; Jenner, Matthew
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Gladiolin produced by pathogenic Burkholderia synergizes with amphotericin B through membrane lipid rearrangements
errMBIO
IF4.7
err2024-11-13
err0
errOAAI
errSimm, Claudia; Lee, Tzong-Hsien; Weerasinghe, Harshini; Walsh, Dean; Nakou, Ioanna T.; Shankar, Madhu; Tse, Wai Chung; Zhang, Yu; Inman, Rebecca; Mulder, Roger J.; Harrison, Freya; Aguilar, Marie-Isabel; Challis, Gregory L.; Traven, Ana
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err收藏
Discovery and Biosynthesis of Persiathiacins: Unusual Polyglycosylated Thiopeptides Active Against Multidrug Resistant Tuberculosis
errACS INFECTIOUS DISEASES
IF3.8
err2024-08-27
err1
errOAAI
errDashti, Yousef; Mohammadipanah, Fatemeh; Zhang, Yu; Cerqueira Diaz, Pietra M.; Vocat, Anthony; Zabala, Daniel; Fage, Christopher D.; Romero-Canelon, Isolda; Bunk, Boyke; Sproer, Cathrin; Alkhalaf, Lona M.; Overmann, Joerg; Cole, Stewart T.; Challis, Gregory L.
err分享
err收藏
Discovery and Biosynthesis of Streptolateritic Acids A-D: Acyclic Pentacarboxylic Acids from Streptomyces sp. FXJ1.172 with Promising Activity against Potato Common Scab
errJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
IF6.2
err2024-06-20
err0
PREAI
errWang, Kairui; Liu, Ning; Liu, Minghao; Zhao, Pan; Zhong, Naiqin; Challis, Gregory L.; Huang, Ying
err分享
err收藏
Native ESI-MS and Collision-Induced Unfolding (CIU) of the Complex between Bacterial Elongation Factor-Tu and the Antibiotic Enacyloxin IIa
errJOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
IF2.7
err2024-06-03
err0
errOAAI
errBaines, Cameron; Sargeant, Jacob; Fage, Christopher D.; Pugh, Hannah; Alkhalaf, Lona M.; Challis, Gregory L.; Oldham, Neil J.
err分享
err收藏
Antibiotic Skeletal Diversification via Differential Enoylreductase Recruitment and Module Iteration in trans-Acyltransferase Polyketide Synthases
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-02-23
err2
errOAAI
errJian, Xinyun; Pang, Fang; Hobson, Christian; Jenner, Matthew; Alkhalaf, Lona M.; Challis, Gregory L.
err分享
err收藏
Metagenomic domain substitution for the high-throughput modification of nonribosomal peptides
errNATURE CHEMICAL BIOLOGY
IF13.7
err2023-11-23
err9
errOAAI
errMessenger, Sarah R.; Mcguinniety, Edward M. R.; Stevenson, Luke J.; Owen, Jeremy G.; Challis, Gregory L.; Ackerley, David F.; Calcott, Mark J.
err分享
err收藏
Parallelized gene cluster editing illuminates mechanisms of epoxyketone proteasome inhibitor biosynthesis
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-01-31
err5
errOAAI
errHuang, Chuan; Zabala, Daniel; de los Santos, Emmanuel L. C.; Song, Lijiang; Corre, Christophe; Alkhalaf, Lona M.; Challis, Gregory L.
err分享
err收藏
Diene incorporation by a dehydratase domain variant in modular polyketide synthases
errNATURE CHEMICAL BIOLOGY
IF13.7
err2022-09-15
err2
errOAAI
errHobson, Christian; Jenner, Matthew; Jian, Xinyun; Griffiths, Daniel; Roberts, Douglas M.; Rey-Carrizo, Matias; Challis, Gregory L.
err分享
err收藏
Cloning and expression of Burkholderia polyyne biosynthetic gene clusters in Paraburkholderia hosts provides a strategy for biopesticide development
errMICROBIAL BIOTECHNOLOGY
IF5.2
err2022-07-13
err10
errOAAI
errPetrova, Yoana D.; Zhao, Jinlian; Webster, Gordon; Mullins, Alex J.; Williams, Katherine; Alswat, Amal S.; Challis, Gregory L.; Bailey, Andy M.; Mahenthiralingam, Eshwar
err分享
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研究方向

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