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G

Gregory R. Bowman

University of Pennsylvania

58H指数
211论文数
1.2W被引数
收录论文 89
发表时间
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Different Substitutions at the Same β-Myosin Residue Underlie Divergent Molecular Phenotypes and Distinct Cardiomyopathies同一β-肌球蛋白残基上的不同取代导致分子表型差异和不同类型的心肌病
errJournal of Biological Chemistry
IF3.9
err2026-09-23
err0
errOAAI
errSarah J. Lehman; Artur Meller; Shahlo O. Solieva; Jeffrey M. Lotthammer; Lina Greenberg; Stephen J. Langer; Michael J. Greenberg; Jil C. Tardiff; Gregory R. Bowman; Leslie Leinwand
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err收藏
SGLT2 inhibitors activate pantothenate kinase in the human heartSGLT2抑制剂在人类心脏中激活泛酸激酶
errScience
IF45.8
err2026-08-27
err0
PREAI
errNicholas Forelli; Trace Thome; Deborah M. Eaton; Kollin Schultz; Jiten Patel; Caitlyn E. Bowman; Ryo Kawakami; Jae Woo Jung; Ivan A. Kuznetsov; Kristina Li; Jialiu A. Liang; Kirsten Branch; Claire Brady; Kenneth C. Bedi; Yijun Yang; Kaustubh Koya; Nesrine Bouhrira; Emily Megill; Daniel S. Kantner; Louis G. Smith; Cristin F. MacIntosh; Kushol Gupta; Gregory R. Bowman; Nathaniel W. Snyder; Jonathan Edwards; Kenneth B. Margulies; Zoltan Arany
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How Well Can AI and Physics-Based Simulations Predict the Probability a Cryptic Pocket Is Open?AI和基于物理的模拟能多好地预测隐匿口袋打开的概率？
errJournal of Chemical Theory and Computation
IF5.5
err2026-04-07
err0
PREAI
errSi Zhang; Justin J. Miller; Gregory R. Bowman
err分享
err收藏
Reduced catalytic activity of KPC β-lactamase can increase ceftazidime resistanceKPC β-内酰胺酶催化活性降低可增加ceftazidime耐药性
errCommunications Biology
IF5.1
err2026-04-07
err0
errOAAI
errAndré Birgy; Dignite Fabrice Ngango; Murugesan Palaniappan; Shahlo O. Solieva; Devin G. Kelly; Zhizeng Sun; Gregory Bowman; Timothy Palzkill
err分享
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Introduction to Markov State Modeling of Conformational Dynamics构象动力学马尔可夫状态建模导论
errJournal of Chemical Theory and Computation
IF5.5
err2026-03-24
err0
PREAI
errBowman, Gregory R.; Clementi, Cecilia; Huang, Xuhui
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Decrypting cryptic pockets with physics-based simulations and artificial intelligence使用基于物理的模拟和人工智能解密神秘口袋
errCurrent Opinion in Structural Biology
IF7
err2026-01-27
err0
errOAAI
errSi Zhang; Gregory R. Bowman
err分享
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The Yeh pilus adhesin is equipped with an α-helical flap motif, which contributes to pectin adherence耶氏菌菌毛黏附素配备有α螺旋翼状基序，有助于果胶黏附
errScience Advances
IF12.5
err2026-01-07
err0
PREAI
errTamadonfar, Kevin O.; Klein, Roger D.; Lopatto, Edward D. B.; Zimmerman, Maxwell I.; Azimzadeh, Philippe N.; Sanick, Denise A.; Porter, Justin R.; Villicana, Jesus Bazan; Pinkner, Jerome S.; Chiang, Bo Huey; Gualberto, Nathaniel C.; Dodson, Karen W.; Patnode, Michael L.; Birchenough, George M. H.; Bowman, Gregory R.; Hultgren, Scott J.
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Pathogenic BRCA1 Mutations Disrupt Allosteric Control by BARD1致病性BRCA1突变破坏了BARD1的别构调控
errThe Journal of Physical Chemistry B
IF0
err2025-07-29
err0
PREAI
errAyan Bhattacharjee; Gregory R. Bowman
err分享
err收藏
The G Protein Inhibitor YM-254890 is an Allosteric GlueG蛋白抑制剂YM-254890是一种别构胶水
errJournal of Molecular Biology
IF4.5
err2025-03-13
err0
errOAAI
errTony Trent; Justin J. Miller; Kendall J. Blumer; Gregory R. Bowman
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Regulating IL-2 Immune Signaling Function Via A Core Allosteric Structural Network通过一个核心别构结构网络调控IL-2免疫信号功能
errJOURNAL OF MOLECULAR BIOLOGY
IF4.5
err2025-01-01
err0
errOAAI
errWoodward, Claire H.; Solieva, Shahlo O.; Hwang, Daniel; Paula, Viviane S. De; Fabilane, Charina S.; Young, Michael C.; Trent, Tony; Teeley, Ella C.; Majumdar, Ananya; Spangler, Jamie B.; Bowman, Gregory R.; Sgourakis, Nikolaos G.
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Accounting for Fast vs Slow Exchange in Single Molecule FRET Experiments Reveals Hidden Conformational States单分子FRET实验中快速与慢速交换的解释揭示了隐藏的构象状态
errJOURNAL OF CHEMICAL THEORY AND COMPUTATION
IF5.5
err2024-11-26
err0
errOAAI
errMiller, Justin J.; Mallimadugula, Upasana L.; Zimmerman, Maxwell I.; Stuchell-Brereton, Melissa D.; Soranno, Andrea; Bowman, Gregory R.
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Stabilization of interdomain closure by a G protein inhibitor
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-08-28
err0
errOAAI
errTodd, Tyson D.; Vithani, Neha; Singh, Sukrit; Bowman, Gregory R.; Blumer, Kendall J.; Soranno, Andrea
err分享
err收藏
Annual Review of Biomedical Data Science AlphaFold and Protein Folding : Not Dead Yet! The Frontier Is Conformational Ensembles
errANNUAL REVIEW OF BIOMEDICAL DATA SCIENCE
IF6
err2024-08-23
err4
PREAI
errBowman, Gregory R.
err分享
err收藏
Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conferenceAPOE和痴呆症研究的进展: 2023 AAIC进展的亮点: APOE会议
errALZHEIMERS & DEMENTIA
IF11.1
err2024-07-19
err1
errOAAI
errKloske, Courtney M.; Belloy, Michael E.; Blue, Elizabeth E.; Bowman, Gregory R.; Carrillo, Maria C.; Chen, Xiaoying; Chiba-Falek, Ornit; Davis, Albert A.; Di Paolo, Gilbert; Garretti, Francesca; Gate, David; Golden, Lesley R.; Heinecke, Jay W.; Herz, Joachim; Huang, Yadong; Iadecola, Costantino; Johnson, Lance A.; Kanekiyo, Takahisa; Karch, Celeste M.; Khvorova, Anastasia; Koppes-den Hertog, Sascha J.; Lamb, Bruce T.; Lawler, Paige E.; Guen, Yann Le; Litvinchuk, Alexandra; Liu, Chia-Chen; Mahinrad, Simin; Marcora, Edoardo; Marino, Claudia; Michaelson, Danny M.; Miller, Justin J.; Morganti, Josh M.; Narayan, Priyanka S.; Naslavsky, Michel S.; Oosthoek, Marlies; Ramachandran, Kapil V.; Ramakrishnan, Abhirami; Raulin, Ana-Caroline; Robert, Aiko; Saleh, Rasha N. M.; Sexton, Claire; Shah, Nilomi; Shue, Francis; Sible, Isabel J.; Soranno, Andrea; Strickland, Michael R.; Julia, T. C. W.; Thierry, Manon; Tsai, Li-Huei; Tuckey, Ryan A.; Ulrich, Jason D.; van der Kant, Rik; Wang, Na; Wellington, Cheryl L.; Weninger, Stacie C.; Yassine, Hussein N.; Zhao, Na; Bu, Guojun; Goate, Alison M.; Holtzman, David M.
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Homologous mutations in human β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-02-20
err1
errOAAI
errLiu, Chao; Karabina, Anastasia; Meller, Artur; Bhattacharjee, Ayan; Agostino, Colby J.; Bowman, Greg R.; Ruppel, Kathleen M.; Spudich, James A.; Leinwand, Leslie A.
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PopShift: A Thermodynamically Sound Approach to Estimate Binding Free Energies by Accounting for Ligand-Induced Population Shifts from a Ligand-Free Markov State Model
errJOURNAL OF CHEMICAL THEORY AND COMPUTATION
IF5.5
err2024-01-31
err3
errOAAI
errSmith, Louis G.; Novak, Borna; Osato, Meghan; Mobley, David L.; Bowman, Gregory R.
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Folding@home: Achievements from over 20 years of citizen science herald the exascale era
errBIOPHYSICAL JOURNAL
IF3.1
err2023-07-01
err24
errOAAI
errVoelz, Vincent A.; Pande, Vijay S.; Bowman, Gregory R.
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Remembering the Work of Phillip L. Geissler: A Coda to His Scientific Trajectory
errANNUAL REVIEW OF PHYSICAL CHEMISTRY
IF11.7
err2023-04-24
err0
errOAAI
errBowman, Gregory R.; Cox, Stephen J.; Dellago, Christoph; Dubay, Kateri H.; Eaves, Joel D.; Fletcher, Daniel A.; Frechette, Layne B.; Grunwald, Michael; Klymko, Katherine; Ku, JiYeon; Omar, Ahmad K.; Rabani, Eran; Reichman, David R.; Rogers, Julia R.; Rosnik, Andreana M.; Rotskoff, Grant M.; Schneider, Anna R.; Schwierz, Nadine; Sivak, David A.; Vaikuntanathan, Suriyanarayanan; Whitelam, Stephen; Widmer-Cooper, Asaph
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Discovery of a cryptic pocket in the AI-predicted structure of PPM1D phosphatase explains the binding site and potency of its allosteric inhibitors
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2023-04-18
err6
errOAAI
errMeller, Artur; De Oliveira, Saulo; Davtyan, Aram; Abramyan, Tigran; Bowman, Gregory R.; van den Bedem, Henry
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What if all your favorite proteins are druggable
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errBowman, Gregory R.
err分享
err收藏

研究方向

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合作学者
合作期刊
D
David M. Holtzman
H 指数: 204 · 论文数: 1.0K
A
Alison Goate
H 指数: 155 · 论文数: 1.2K
W
Warren J. Leonard
H 指数: 128 · 论文数: 544
C
Costantino Iadecola
H 指数: 127 · 论文数: 629
L
Leonidas Guibas
H 指数: 120 · 论文数: 886
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