Hon‐Kan Yip - Publications, H-index & Citations

Hon‐Kan Yip

department of internal medicine

58H指数

517论文数

1.3W被引数

收录论文 224

发表时间

Mitofusin-2 overexpression in adipose tissue-derived mesenchymal stem cells protects the testis against testicular torsion-induced ischemia–reperfusion injury through preservation of mitochondrial homeostasis associated with AMPK activation 脂肪组织来源的间充质干细胞中过表达线粒体融合蛋白2通过维持与AMPK激活相关的线粒体稳态来保护睾丸免受睾丸扭转诱导的缺血-再灌注损伤

Stem Cell Research & Therapy

IF7.3

2026-08-04

OAAI

Yen-Ta Chen; Jui-Po Yeh; Yei-Tsung Chen; Yi-Ling Chen; Yi-Ting Wang; Chi-Ruei Huang; Pei-Lin Shao; Chih-Chao Yang; Hon‐Kan Yip

Early Dapagliflozin and Melatonin Treatment Ameliorated LV Fibrosis via Suppressing TGF-β1/Smads and Activating Nrf2-ARE Signaling in MI Rodent 早期达格列净和褪黑素治疗通过抑制TGF-β1/Smads并激活Nrf2-ARE信号通路改善了心室纤维化，在心肌梗死啮齿动物模型中。

The Kaohsiung Journal of Medical Sciences

IF0

2026-04-02

OAAI

Jiunn-Jye Sheu; Jui-Ning Yeh; Han-Tan Chai; John Y. Chiang; Chi-Ruei Huang; Jun Guo; Hon-Kan Yip

Double gene overexpression of ZNF746 and cellular prion protein in rat adipose-derived mesenchymal stromal cell therapy protects the liver against ischemia‒reperfusion injury ZNF746和细胞朊蛋白的双重基因过表达在来源于大鼠脂肪组织的间充质基质细胞疗法中保护肝脏免受缺血-再灌注损伤

Cell Transplantation

IF3.2

2025-10-17

OAAI

Sheung-Fat Ko; Chi-Ruei Huang; John Y. Chiang; Yi-Ling Chen; Hon-Kan Yip

Combined Deletion of Mitofusin 2 in Adipose-Mesenchymal Derived Stem Cells and Melatonin Offers Additional Benefits on Protecting the Brain Against Acute Ischemic Stroke in Rat 联合删除脂肪间充质来源干细胞中的线粒体融合蛋白2与褪黑素，可为大鼠急性缺血性脑卒中提供额外的脑保护益处。

Antioxidants & Redox Signaling

IF6.1

2025-08-14

PREAI

Chien-Hui Yang; Hung-Sheng Lin; Han-Tan Chai; Yi-Ling Chen; Hon-Kan Yip; Kuan-Hung Chen

Adipose-derived mesenchymal stem cell-supported ciprofloxacin therapy effectively protects the kidney parenchyma and functional integrity against acute pyelonephritis damage in rodents 脂肪来源间充质干细胞支持的环丙沙星疗法可有效保护啮齿动物肾实质和功能完整性，免受急性肾盂肾炎损伤。

Cell Transplantation

IF3.2

2025-06-24

OAAI

Chih-Chao Yang; Ya Yue; Pei-Lin Shao; Ben-Chung Cheng; Tsuen-Wei Hsu; Yi-Ling Chen; Sheung-Fat Ko; Hon-Kan Yip; Mel S. Lee

Febuxostat therapy improved the outcomes of cardiorenal syndrome rodent through alleviating xanthine oxidase-induced oxidative stress and mitochondrial dysfunction Febuxostat疗法通过缓解黄嘌呤氧化酶诱导的氧化应激和线粒体功能障碍，改善了心肾综合征啮齿动物模型的结局。

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES

IF10

2025-02-10

OAAI

Yang, Chih-Chao; Yue, Ya; Chen, Yi-Ling; Chiang, John Y.; Wang, Yi-Ting; Huang, Chi-Ruei; Cheng, Ben-Chung; Hsu, Tsuen-Wei; Yip, Hon-Kan

Shock wave-pretreated ADMSCs of cell-sheet scaffold (CSS) patched on the left ventricular wall (LVW) inhibited LVW remodeling in mini-pig MI: role of CSS on counteracting Laplace's Law of LVW stress - experimental study

INTERNATIONAL JOURNAL OF SURGERY

IF10.1

2024-12-01

OAAI

Sheu, Jiunn-Jye; Yeh, Jui-Ning; Chen, Yin-Chia; Chiang, John Y.; Sung, Pei-Hsun; Huang, Chi-Ruei; Li, Yi-Chen; Yip, Hon-Kan

Long term outcomes of intracarotid arterial transfusion of circulatory-derived autologous CD34+cells for acute ischemic stroke patients-A randomized, open-label, controlled phase II clinical trial

STEM CELL RESEARCH & THERAPY

IF7.3

2024-11-20

OAAI

Lin, Hung-Sheng; Sung, Pei-Hsun; Huang, Shu-Hua; Lin, Wei-Che; Chiang, John Y.; Ma, Ming-Chun; Chen, Yi-Ling; Chen, Kuan-Hung; Lee, Fan-Yen; Ko, Sheung-Fat; Yip, Hon-Kan

Synergic effect of combined xenogeneic mesenchymal stem cells and ceftriaxone on acute septic arthritis

STEM CELLS TRANSLATIONAL MEDICINE

IF4.9

2024-06-03

OAAI

Sung, Pei-Hsun; Yin, Tsung-Cheng; Chiang, John Y.; Chen, Chih-Hung; Huang, Chi-Ruei; Lee, Mel S.; Yip, Hon-Kan

ITRI Biofilm Prevented Thoracic Adhesion in Pigs That Received Myocardial Ischemic Induction Treated by Myocardial Implantation of EPCs and ECSW Treatment

CELL TRANSPLANTATION

IF3.2

2024-05-26

OAAI

Sheu, Jiunn-Jye; Yeh, Jui-Ning; Sung, Pei-Hsun; Chiang, John Y.; Chen, Yi-Ling; Wang, Yi-Ting; Yip, Hon-Kan; Guo, Jun

Repeated administration of adipose-derived mesenchymal stem cells added on beneficial effects of empagliflozin on protecting renal function in diabetic kidney disease rat 脂肪间充质干细胞添加恩格列净对糖尿病肾病大鼠肾功能的保护作用

BIOMEDICAL JOURNAL

IF4.4

2024-04-01

OAAI

Yang, Chih-Chao; Chen, Yi-Ling; Sung, Pei-Hsun; Chiang, John Y.; Chen, Chih-Hung; Li, Yi-Chen; Yip, Hon-Kan

Engineered extracellular vesicles carrying let-7a-5p for alleviating inflammation in acute lung injury

JOURNAL OF BIOMEDICAL SCIENCE

IF12.1

2024-03-19

OAAI

Chen, Sin-Yu; Chen, Yi-Ling; Li, Po-Chen; Cheng, Tai-Shan; Chu, Yeh-Shiu; Shen, Yi-Shan; Chen, Hsin-Tung; Tsai, Wei-Ni; Huang, Chien-Ling; Sieber, Martin; Yeh, Yuan-Chieh; Liu, Hsiao-Sheng; Chiang, Chi-Ling; Chang, Chih-Hung; Lee, Andrew S.; Tseng, Yen-Han; Lee, Ly James; Liao, Hsiu-Jung; Yip, Hon-Kan; Huang, Chi-Ying F.

Prion Protein Overexpression in Adipose-Derived Mesenchymal Stem Cells (ADMSCs) Effectively Protected Rodent Kidney Against Ischemia-Reperfusion Injury Via Enhancing ATP/Mitochondrial Biogenesis-Role of ADMSC Rejuvenation and Proliferation

CELL TRANSPLANTATION

IF3.2

2023-12-11

OAAI

Chen, Yen-Ta; Yang, Chih-Chao; Chiang, John Y.; Sung, Pei-Hsun; Shao, Pei-Lin; Huang, Chi-Ruei; Lee, Mel S.; Yip, Hon-Kan

ZNF746 plays cardinal roles on colorectal cancer (CRC) cell invasion and migration and regulates mitochondrial dynamics and morphological changes of CRC cells-Role of combined melatonin and 5-FU regimen

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2023-12-04

PREAI

Huang, Chi-Ruei; Chu, Yu-Ting; Chang, Chia-Lo; Yip, Hon-Kan; Chen, Hong-Hwa

Early and Dose-Dependent Xenogeneic Mesenchymal Stem Cell Therapy Improved Outcomes in Acute Respiratory Distress Syndrome Rodent Through Ameliorating Inflammation, Oxidative Stress, and Immune Reaction

CELL TRANSPLANTATION

IF3.2

2023-08-17

OAAI

Lin, Kun-Chen; Fang, Wen-Feng; Sung, Pei-Hsun; Huang, Kuo-Tung; Chiang, John Y.; Chen, Yi-Ling; Huang, Chi-Ruei; Li, Yi-Chen; Lee, Mel S.; Yip, Hon-Kan

Oxidized-LDL Deteriorated the Renal Residual Function and Parenchyma in CKD Rat through Upregulating Epithelial Mesenchymal Transition and Extracellular Matrix-Mediated Tubulointerstitial Fibrosis-Pharmacomodulation of Rosuvastatin

ANTIOXIDANTS

IF6.6

2022-12-15

OAAI

Sung, Pei-Hsun; Cheng, Ben-Chung; Hsu, Tsuen-Wei; Chiang, John Y.; Chiang, Hsin-Ju; Chen, Yi-Ling; Yang, Chih-Chao; Yip, Hon-Kan

Synergic Effect of Combined Therapy of Hyperbaric Oxygen and Adipose-Derived Mesenchymal Stem Cells on Improving Locomotor Recovery After Acute Traumatic Spinal Cord Injury in Rat Mainly Through Downregulating Inflammatory and Cell-Stress Signalings

CELL TRANSPLANTATION

IF3.2

2022-11-01

OAAI

Yin, Tsung-Cheng; Shao, Pei-Lin; Chen, Kuan-Hung; Lin, Kun-Chen; Chiang, John Y.; Sung, Pei-Hsun; Wu, Shun-Cheng; Li, Yi-Chen; Yip, Hon-Kan; Lee, Mel S.

Association of Nitric Oxide Synthase Polymorphism and Coagulopathy in Patients with Osteonecrosis of the Femoral Head

JOURNAL OF CLINICAL MEDICINE

IF2.9

2022-08-24

OAAI

Wu, Cheng-Ta; Lin, Rio L. C.; Sung, Pei-Hsun; Kuo, Feng-Chih; Yip, Hon-Kan; Lee, Mel S.

Dose-dependent benefits of iron-magnetic nanoparticle-coated human umbilical-derived mesenchymal stem cell treatment in rat intracranial hemorrhage model

STEM CELL RESEARCH & THERAPY

IF7.3

2022-06-21

OAAI

Chen, Kuan-Hung; Chai, Han-Tan; Lin, Kun-Chen; Chiang, John Y.; Sung, Pei-Hsun; Chen, Chih-Hung; Yip, Hon-Kan