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H

Hung‐wen Liu

University of Texas at Austin

59H指数
344论文数
1.2W被引数
收录论文 172
发表时间
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A Novel Amidation Reaction Couples Siderophore Bait with the SB-217452 Warhead to Complete the Biosynthesis of the Trojan-Horse Antibiotic Albomycin δ2一种新型酰胺化反应将铁载体诱饵与SB-217452 warhead偶联，以完成木马马抗生素Albomycin δ2的生物合成
errJournal of the American Chemical Society
IF15.6
err2026-05-20
err0
PREAI
errHouyuan Zhao; Hung-wen Liu
err分享
err收藏
Transfer RNA deacylases as beacons for non-canonical amino acid biosynthesis转移RNA去酰化酶作为非规范氨基酸生物合成中的信标
errNature Chemistry
IF20.2
err2026-05-01
err0
PREAI
errLee, Yu-Hsuan; Liu, Hung-wen
err分享
err收藏
Fluorogenic Aptamer Optimization on a Massively Parallel Sequencing Platform基于大规模并行测序平台的荧光探针优化
errACS Sensors
IF9.1
err2026-05-01
err0
PREAI
errKuo, Yu-An; Chen, Yuan-, I; Siraj, Naseem; He, Yujie; Yang, Zhenglin; Wang, Yanxing; Batchelder-Schwab, Emile J.; Korkmaz, Zeynep; Yonas, Siem; Nguyen, Trung D.; Hong, Soonwoo; Nguyen, Anh-Thu; Kim, Sohyun; Seifi, Saeed; Fan, Po-Hsun; Wu, Yuting; Liu, Hung-Wen; Lu, Yi; Ren, Pengyu; Mao, Chengde; Yeh, Hsin-Chih
err分享
err收藏
The Radical SAM Enzyme BlsE Can Operate as a Dehydratase; Dehydrogenase; or Epimerase upon Mutation of a Single Active Site Serine ResidueRadical SAM酶BlsE在单个活性位点丝氨酸残基突变后，可作为脱氢酶、脱氢酶或差向异构酶发挥作用。
errJournal of the American Chemical Society
IF15.6
err2026-02-10
err0
PREAI
errYu-Hsuan Lee; Ziyang Zheng; Baixu Ma; Daan Ren; Mark W. Ruszczycky; Lizhi Tao; Hung-wen Liu
err分享
err收藏
Refining the Substrate-Cofactor Disposition Model of Hyoscyamine 6β-Hydroxylase Catalysis Using Hyoscyamine Analogs利用莨菪碱类似物优化莨菪碱6β-羟化酶催化的底物-辅因子排布模型
errJournal of the American Chemical Society
IF15.6
err2025-12-02
err0
PREAI
errRichiro Ushimaru; Ridao Chen; Po-Hsun Fan; Xiao Liu; Mark W. Ruszczycky; Hung-wen Liu
err分享
err收藏
Pyrazofurin Biosynthesis Involves Nonenzymatic Ring Contraction of a Pyridazine Intermediate Triggered by a Rieske Enzyme-Catalyzed Oxygenation吡唑呋喃素生物合成涉及由Rieske酶催化的氧化作用触发的吡嗪中间体的非酶促环收缩。
errJournal of the American Chemical Society
IF15.6
err2025-10-29
err0
PREAI
errZiyang Zheng; Yu-Hsuan Lee; Daan Ren; Hung-wen Liu
err分享
err收藏
A Selenium-for-Oxygen Swapping Reaction Catalyzed by the Radical S-Adenosyl Methionine Enzyme AbmM一种由自由基S-腺苷甲硫氨酸酶AbmM催化的硒代-氧交换反应
errJournal of the American Chemical Society
IF15.6
err2025-10-29
err0
PREAI
errZiyang Zheng; Yu-Hsuan Lee; Hung-wen Liu
err分享
err收藏
Characterization of C3’ Epimerization of the Thioheptose Core in the Biosynthesis of Albomycin δ2 Catalyzed by the Radical S-Adenosylmethionine Enzyme AbmJC3’位差向异构化在Albomycin δ2生物合成中硫庚糖核心的表征，由自由基S-腺苷甲硫氨酸酶AbmJ催化
errACS Catalysis
IF13.1
err2025-10-17
err0
PREAI
errHouyuan Zhao; Zhang Chen; Joseph L. Franklin; Hung-Wen Liu
err分享
err收藏
Structure-Guided Mechanistic Investigation of Stereochemical Inversion during the Octose Formation Catalyzed by an Atypical Transaldolase AprG in the Biosynthesis of Apramycin结构指导的机制研究：在阿普霉素生物合成中，由非典型转醛醇酶AprG催化的辛酮糖形成过程中的立体化学反转
errACS Catalysis
IF13.1
err2025-07-25
err0
PREAI
errWantae Kim; Po-Hsun Fan; Junling Bu; Hung-wen Liu; Y. Jessie Zhang
err分享
err收藏
Radical S-adenosyl-l-methionine FeS cluster implicated as the sulfur donor during albomycin biosynthesis自由基S-腺苷-l-蛋氨酸FeS簇在阿比霉素生物合成过程中被认为是硫供体
errNature Catalysis
IF44.6
err2025-07-15
err0
PREAI
errRichiro Ushimaru; Ziyang Zheng; Jin Xiong; Takahiro Mori; Ikuro Abe; Yisong Guo; Hung-wen Liu
err分享
err收藏
A [2.1.0]-Fused Bicyclic Intermediate Is Produced during the Biosynthesis of Oxetane Nucleosides在氧杂环丁烷核苷的生物合成过程中会产生一个[2.1.0]-稠合的双环中间体
errJournal of the American Chemical Society
IF15.6
err2025-07-11
err0
PREAI
errYu-Hsuan Lee; Po-Hsun Fan; Yu-Cheng Yeh; Mark W. Ruszczycky; Yujie Geng; Aoshu Zhong; Hung-wen Liu
err分享
err收藏
Blasticidin S Biosynthesis Involves a Unique Interplay between a Radical SAM Dehydratase, a Transaminase and an ATP-Grasp Ligase in Order to Avoid a Futile CycleBlasticidin S的生物合成涉及一种独特的相互作用，包括一个自由基SAM脱水酶、一个转氨酶和一个ATP-Grasp连接酶，以避免无效循环。
errACS CATALYSIS
IF13.1
err2025-01-30
err0
PREAI
errLee, YH; Ren, D; Chen, RD; Liu, X; Engstrom, A; Liu, HW
err分享
err收藏
Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S-Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase (vol 144, pg 9910, 2022)双氧环己烷桥在棘霉素生物合成中的形成涉及一种跳变自由基S-腺苷甲硫氨酸脱氢酶，该酶可能由一种表异构酶进化而来（卷144，页9910，2022）
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2025-01-10
err0
PREAI
errZhang, Jiawei; Hou, Xueli; Chen, Zhang; Ko, Yeonjin; Ruszczycky, Mark W.; Chen, Yutian; Zhou, Jiahai; Liu, Hung-wen
err分享
err收藏
In Vitro Characterization of Kitasetaline Biosynthesis Reveals a Bifunctional P450 Decarboxylase and a Vinyl β-Carboline Intermediate Susceptible to Nonenzymatic Thiol Addition
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-10-03
err0
PREAI
errZheng, Ziyang; Choi, Heewon; Liu, Hung-wen
err分享
err收藏
Biosynthesis of the Unusual Epoxy Isonitrile-Containing Antibiotics Aerocyanidin and Amycomicin
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-07-23
err1
errOAAI
errZheng, Ziyang; Clardy, Jon; Liu, Hung-wen
err分享
err收藏
Mechanistic Insights from the Crystal Structure and Computational Analysis of the Radical SAM Deaminase DesII自由基SAM脱氨酶DesII的晶体结构和计算分析的机理见解
errADVANCED SCIENCE
IF14.1
err2024-06-28
err0
errOAAI
errHou, Xueli; Feng, Jianqiang; Franklin, Joseph Livy; Russo, Ryan; Guo, Zhiyong; Zhou, Jiahai; Gao, Jin-Ming; Liu, Hung-wen; Wang, Binju
err分享
err收藏
Complete In Vitro Reconstitution of the Apramycin Biosynthetic Pathway Demonstrates the Unusual Incorporation of a β-d-Sugar Nucleotide in the Final Glycosylation Step
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-03-28
err1
errOAAI
errSato, Shusuke; Fan, Po-Hsun; Yeh, Yu-Cheng; Liu, Hung-wen
err分享
err收藏
Complete in vitro reconstitution of the apramycin biosynthetic pathway demonstrates incorporation of a β-D-sugar nucleotide
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errSato, Shusuke; Fan, Po-Hsun; Yeh, Yu-Cheng; Liu, Hung-wen
err分享
err收藏
Mechanistic studies of the radical SAM enzyme OxsB in oxentanocin A biosynthesis氧戊辛A生物合成中自由基SAM酶OxsB的机理研究
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errLiu, Hung-Wen
err分享
err收藏
Biosynthetic Origin of the Octose Core and Its Mechanism of Assembly during Apramycin Biosynthesis
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2023-09-21
err3
errOAAI
errFan, Po-Hsun; Sato, Shusuke; Yeh, Yu-Cheng; Liu, Hung-wen
err分享
err收藏

研究方向

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合作学者
合作期刊
仉华 封面图
仉华 (Hua Zhang)
H 指数: 205 · 论文数: 2.7K
K
K. N. Houk
H 指数: 157 · 论文数: 2.6K
J
Jon Clardy
H 指数: 137 · 论文数: 1.4K
L
Lawrence Que
H 指数: 116 · 论文数: 823
张
张立欣 (Lixin Zhang)
H 指数: 104 · 论文数: 1.2K
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